-
Question 1
Correct
-
Transportation of proteins from the cell body to axonal terminals is known as:
Your Answer: Axoplasmic flow
Explanation:Transportation of proteins from the cell body to axonal terminals is known as axoplasmic, axonal flow or Axonal transport.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 2
Correct
-
The cavernous sinus is?
Your Answer: Lateral to the body of the sphenoid
Explanation:It is a venous sinus which creates a cavity called the lateral sellar compartment bordered by the temporal bone and the sphenoid bone. There are 2 on either side. It is about 1cm wide and extends from the posterior aspect of the orbit to the petrous part of the temporal bone. They sit on either side or lateral to the sphenoid bone.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 3
Correct
-
The following is true about the carotid arterial supply to the brain:
Your Answer: Following carotid occlusion, precapillary anastomoses are unable to prevent infarction
Explanation:The brain has two sources of blood supply; the internal carotid arteries which are the anterior segment or the main artery that supplies the anterior portion of the brain, and the vertebral arteries which is the posterior segment which supplies the posterior portion of the brain. The internal carotid arteries branch and form two major arteries anterior and middle cerebral arteries. The right and left vertebral arteries fuse together at the level of the pons on the anterior surface of the brainstem to form the midline basilar artery. The basilar artery joins the blood supply from the internal carotids in an arterial ring at the base of the brain called the circle of Willis. The anterior and posterior communicating arteries conjoin the two major sources of cerebral vascular supply via the circle of Willis improving the chances of any region of the brain continuing to receive blood if one of the major arteries becomes occluded.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 4
Correct
-
The motor speech area (Brocas Area) is:
Your Answer: Brodmann area 44
Explanation:A Brodmann area in the brain is defined by cytoarchitecture, histology and organization of cells:Primary Sensory 3,1,2Primary Motor 4Premotor 6Primary Visual 17Primary Auditory 41Brocas 44
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 5
Correct
-
Activation of the cool receptor (CMR-1), causes:
Your Answer: Influx of Ca++ & Na+
Explanation:Cold and Menthol receptor 1 (CMR1) is a protein that in humans is encoded by TRPM8 gene. It is an ion channel which upon activation causes the influx of Na+ and Ca++ ions into the cell that leads to the depolarization and generation of an action potential.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 6
Correct
-
Visceral afferent fibers are found in the following areas except the…?
Your Answer: Trigeminal nerve
Explanation:The general visceral afferent (GVA) fibers carry impulses from viscera to the central nervous system. The cranial nerves that contain GVA fibers include the facial nerve, the glossopharyngeal nerve and the vagus nerve
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 7
Correct
-
The hippocampus is involved in the memory of:
Your Answer: Facts
Explanation:The hippocampus plays an important role in forming new memories about experienced events. Some researchers say that hippocampus plays a major role in declarative memory for example memory of facts.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 8
Incorrect
-
The thalamic main input from the cortex is via which tracts?
Your Answer: Thalamospinal pathway
Correct Answer: Thalamocortical pathway
Explanation:The thalamus is connected to cerebral cortex via the thalamocortical radiation.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 9
Correct
-
Neurogenesis occurs throughout life in the following two areas:
Your Answer: Hippocampus and striatum
Explanation:In humans, neurogenesis or new neurons are continually born during adulthood in two regions of the brain: The subgranular zone (SGZ), part of the dentate gyrus of the hippocampus and the striatum. In other species of mammals, adult-born neurons also appear in the olfactory bulb. In humans, however, few if any olfactory bulb neurons are generated after birth.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 10
Correct
-
Which receptor type is associated with the inhibition of pancreatic endocrine secretion?
Your Answer: Α2
Explanation:The activation of alpha 2-adrenergic receptors in pancreatic beta-cells works by inhibiting the secretion of insulin.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 11
Correct
-
Which of the following do not pass through the cavernous sinus?
Your Answer: CN 2
Explanation:Oculomotor nerve (N3), trochlear nerve (N4), ophthalmic and mandibular divisions of the trigeminal nerve (N5) pass along its lateral border. The abducent nerve (N6) passes through it along with the internal carotid artery.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 12
Correct
-
Concerning the sleep-wake cycle, Melatonin is secreted by which structure in the brain following which environmental conditions?
Your Answer: Pineal gland, darkness
Explanation:Melatonin is secreted by the pineal gland located in the midline attached to the posterior roof of the third ventricle in the brain. Melatonin affects circadian rhythm in the body or the sleep wake cycle. The precursor to melatonin is serotonin and the rate limiting enzyme that converts serotonin to melatonin is low during the day time and reaches its peak during the night.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 13
Incorrect
-
The small opening in the cochlea through which the upper scala vestibuli and lower scala tympani communicates is called the:
Your Answer: Oval window
Correct Answer: Helicotrema
Explanation:The helicotrema is the part of cochlear labyrinth where the scala tympani and the scala vestibuli meet.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 14
Incorrect
-
Sequence of events in formation of speech are:
Your Answer: Insula---Wernicke's area---arcuate fasciculus---broca’s area---motor cortex ---speech
Correct Answer: Wernicke’s area---arcuate fasciculus---broca’s area---insula---motor cortex---speech
Explanation:Wernicke’s area is located in the categorical hemisphere or left hemisphere in about 95% of right handed individuals and 60% of left handed individuals. It is involved in the comprehension or understanding of written and spoken language. In contrast Broca’s area is involved in production of language. Firstly, the language is accessed in the Wernicke’s area and these words are sent via the arcuate fasciculus to the Broca’s area, where instructions for articulation is generated. This is then sent from Broca’s are to the motor cortex for the articulation.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 15
Incorrect
-
Glucose transport in the brain is mediated by:
Your Answer: All of the above
Correct Answer: GLUT 1
Explanation:The facilitative glucose transporter mediates the transport of glucose from blood into neurons and glia in the brain. The primary isoforms in the brain are GLUT1 detected at high concentrations.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 16
Incorrect
-
The brainstem reticular formation, consists of which important control system responsible for consciousness and sleep?
Your Answer: RES reticular encephalic system
Correct Answer: RAS reticular activating system
Explanation:The reticular formation is a set of interconnected nuclei that are located along the brainstem. Reticular activating system (RAS) is a set of connected nuclei in the brain that is responsible for regulating wakefulness and sleep wake transitions and is the most influential component in the reticular formation.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 17
Incorrect
-
Cold receptors are likely to be active at the following temperatures except?
Your Answer: 10 °C
Correct Answer: 39 °C
Explanation:Cold and Menthol receptor 1 (CMR1) is a protein that in humans is encoded by TRPM8 gene. It is primarily responsible for the detection of temperatures ranging from 8-28 C. It is an ion channel which upon activation causes the influx of Na+ and Ca+ ions into the cell that leads to the depolarization and generation of an action potential.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 18
Incorrect
-
The primary sensory cortex is:
Your Answer: Brodmann area 4
Correct Answer: Brodmann area 3,1,2
Explanation:A Brodmann area in the brain is defined by cytoarchitecture, histology and organization of cells:Primary somatosensory cortex is areas 3,1, and 2Primary Motor 4Premotor 6Primary Visual 17Primary Auditory 41Brocas 44
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 19
Incorrect
-
The neurotransmitter utilised by the Purkinje cells is:
Your Answer: Glycine
Correct Answer: GABA
Explanation:The cerebellar cortex consist of 3 layers: the molecular layer, the granular cell layer and the Purkinje cell layer. Purkinje cells play a fundamental role in controlling motor movement. They release a neurotransmitter called GABA (gamma-aminobutyric acid) which exerts inhibitory actions thereby reducing transmission of impulses. These inhibitory functions enable purkinje cells to regulate and coordinate motor movements.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 20
Correct
-
Endolymph in the inner ear is rich in:
Your Answer: K
Explanation:Cochlear fluids namely endolymph and perilymph have different compositions. Perilymph is a typical extracellular fluid, with ionic composition comparable to plasma or cerebrospinal fluid. The main cation is sodium. Endolymph is a totally unique extracellular fluid, with an ion composition unlike that which is found anywhere else in the body. The major cation in the endolymph is potassium and there is virtually no sodium.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 21
Incorrect
-
Which one of the following nerve fibers is involved in proprioception?
Your Answer: A β fiber
Correct Answer: An α fiber
Explanation:Proprioception, also known as kinaesthesia, is the sense through which humans perceive their own position and movements. α nerve fibers are specifically involved in transmitting proprioception stimuli.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 22
Correct
-
The midbrain, medulla and pons, contain the following cranial nerve nuclei?
Your Answer: CN 3 - 12
Explanation:The cranial nerves (with the exception of I and II) originate in the brainstem, which includes the midbrain, the pons, and the medulla.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 23
Incorrect
-
The premotor cortex is:
Your Answer: Brodmann area 8
Correct Answer: Brodmann area 6
Explanation:A Brodmann area in the brain is defined by cytoarchitecture, histology and organization of cells:Primary Sensory 3,1,2Primary Motor 4Premotor 6Primary Visual 17Primary Auditory 41Brocas 44
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 24
Incorrect
-
Which part of the cerebellum is primarily responsible for equilibrium and eye movements?
Your Answer: Medial hemispheric portions
Correct Answer: Vestibulocerebellum
Explanation:The vestibulocerebellum develops at the same time as the vestibular apparatus in the inner ear. Its regulates balance between agonist and antagonist muscle contractions of the spine, hips, and shoulders during rapid movements.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 25
Incorrect
-
Corticospinal tracts are located in the ___ of the white matter.
Your Answer: Anterior and posterior funiculi
Correct Answer: Anterior and lateral funiculi
Explanation:The corticospinal tract is a descending or a motor tract which projects nerve fibers from the cortex of the cerebrum down to different levels of the spinal cord. The descending corticospinal tract descends from the origin, through the corona radiata, posterior half of the lateral ventricle, and enters the midbrain through the cerebral peduncle. In the medulla they form the medullary pyramids on either side of midline as lateral and anterior fibers.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 26
Incorrect
-
The nucleus ambiguus:
Your Answer: Provides parasympathetic control of the parotid gland
Correct Answer: Regulates swallowing, phonation and parasympathetic supply to the heart via CN IX, X and XI
Explanation:Nucleus Ambiguus is a group of large motor neurons found deep in the medullary reticular formation. It contains cell bodies of nerves that are responsible for the innervation of muscles of speech and swallowing which are located in the soft palate, pharynx and larynx. Additionally, it contains cholinergic preganglionic parasympathetic neurons of the heart via CN X, IX and XI
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 27
Correct
-
Question 28
Incorrect
-
Which of the following tracts are involved in the control of vital functions?
Your Answer: Tectospinal
Correct Answer: Reticulospinal
Explanation:Reticulospinal tract pass down from the reticular formation of the mid brain, pons and medulla. It descends in the lateral white column. Both sets of fibers enter the anterior grey column and may facilitate or inhibit the gamma and alpha neurons. By this means the reticulospinal tract controls voluntary and reflex activities. It also contains the descending autonomic fiber, thus providing a pathway for the hypothalamus to control the sympathetic and parasympathetic pathways.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 29
Incorrect
-
In Argyll Robertson pupils…
Your Answer: It may occur in CNS syphilis
Correct Answer: All of the options given
Explanation:Argyll Robertson pupils are bilaterally small pupils that accommodate or reduce in size near an object but do not react to light. They do not constrict when exposed to bright light. They are a highly specific sign of neurosyphilis but may be seen in diabetic neuropathy as well.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 30
Incorrect
00
Correct
00
Incorrect
00
:
00
:
00
Session Time
00
:
00
Average Question Time (
Secs)