00
Correct
00
Incorrect
00 : 00 : 0 00
Session Time
00 : 00
Average Question Time ( Secs)
Retry this test Dashboard

  • Question 1 - Where is fetal DHEA produced? ...

    Correct

    • Where is fetal DHEA produced?

      Your Answer: Adrenals

      Explanation:

      DHEA is formed in the mother’s adrenal gland as well as the fetal adrenal glands. These weak androgens are transported by the blood to the placenta and are converted into oestradiol, estrone and estriol in the trophoblast.

    • This question is part of the following fields:

      • Endocrinology
      13.3
      Seconds

  • Question 2 - Which major hormone of pregnancy is produced by the placenta from 16-hydroxydehydroepiandrosterone sulphate...

    Correct

    • Which major hormone of pregnancy is produced by the placenta from 16-hydroxydehydroepiandrosterone sulphate (16-OH DHEAS)?

      Your Answer: Estriol

      Explanation:

      The placenta produces Estriol from 16-OH DHEAS. Estriol is the major oestrogen (oestrogen) of pregnancy and the placenta is the primary site of production. Pregnenolone is synthesised by the placenta from cholesterol and this is converted to dehydroepiandrosterone (DHEA) in the fetal adrenal gland

    • This question is part of the following fields:

      • Endocrinology
      23.4
      Seconds

  • Question 3 - The ovaries produce androgen and progesterone. What is the common precursor for both...

    Correct

    • The ovaries produce androgen and progesterone. What is the common precursor for both of these hormones?

      Your Answer: Cholesterol

      Explanation:

      Cholesterol is the common precursor for progesterone and androgen production.

    • This question is part of the following fields:

      • Endocrinology
      76.8
      Seconds

  • Question 4 - Where is fetal DHEA produced? ...

    Correct

    • Where is fetal DHEA produced?

      Your Answer: Adrenals

      Explanation:

      Dehydroepiandrosterone (DHEA) is a steroid hormone synthesised from cholesterol (via Pregnenolone) by the adrenal glands. The foetus manufactures DHEA, which stimulates the placenta to form oestrogen, thus keeping a pregnancy going. Production of DHEA stops at birth, then begins again around age seven and peaks when a person is in their mid-20s

    • This question is part of the following fields:

      • Endocrinology
      3.5
      Seconds

  • Question 5 - Adult Polycystic Kidney Disease (PKD) typically follows which pattern of inheritance ...

    Correct

    • Adult Polycystic Kidney Disease (PKD) typically follows which pattern of inheritance

      Your Answer: Autosomal Dominant

      Explanation:

      PKD can follow either Autosomal dominant or recessive inheritance. Autosomal dominant is however the most common inheritance pattern and is seen in adult PKD. Infantile PKD is recessive

    • This question is part of the following fields:

      • Endocrinology
      6.6
      Seconds

  • Question 6 - The ovaries produce androgen and progesterone. What is the common precursor for both...

    Correct

    • The ovaries produce androgen and progesterone. What is the common precursor for both of these hormones?

      Your Answer: Cholesterol

      Explanation:

      Both the female hormones, namely progesterone and oestrogen as well as the male hormones or androgens are lipid soluble. The common precursor of these is cholesterol.

    • This question is part of the following fields:

      • Endocrinology
      2.5
      Seconds

  • Question 7 - What is the most common cause of premature menopause in the UK? ...

    Correct

    • What is the most common cause of premature menopause in the UK?

      Your Answer: Idiopathic

      Explanation:

      Premature menopause is most commonly idiopathic.

    • This question is part of the following fields:

      • Endocrinology
      4
      Seconds

  • Question 8 - The following hormones are secreted from the anterior pituitary gland, EXCEPT: ...

    Correct

    • The following hormones are secreted from the anterior pituitary gland, EXCEPT:

      Your Answer: HCG

      Explanation:

      The following hormones are excreted from the anterior pituitary gland: TSH, GN, ACTH, LH, FSH, MSH, PRL.
      Human chorionic gonadotropin (hCG, or human chorionic gonadotrophin) is a placental hormone secreted by syncitiotrophoblasts during the second week of gestation.

    • This question is part of the following fields:

      • Endocrinology
      5.2
      Seconds

  • Question 9 - Beta and Delta Thalassemia are associated with abnormalities to which chromosome ...

    Correct

    • Beta and Delta Thalassemia are associated with abnormalities to which chromosome

      Your Answer: Chromosome 11

      Explanation:

      Fetal haemoglobin (HBF) is the main haemoglobin type in the foetus and persists after birth for around 6 months. Fetal haemoglobin is composed of two alpha and two gamma subunits The alpha globulin chain is coded for by genes on Chromosome 16. Alpha Thalassemia are therefore associated with Chromosome16 defects The beta and delta globulin chains are coded for by genes on Chromosome 11. Beta and Delta Thalassemia are therefore associated with Chromosome 11 Defects

    • This question is part of the following fields:

      • Endocrinology
      4.5
      Seconds

  • Question 10 - Adult Polycystic Kidney Disease (PKD) typically follows which pattern of inheritance ...

    Correct

    • Adult Polycystic Kidney Disease (PKD) typically follows which pattern of inheritance

      Your Answer: Autosomal Dominant

      Explanation:

      Polycystic kidney disease (PKD) can either be autosomal dominant or recessive. The autosomal dominant variant is more common in adult PKD however, the recessive pattern is more common in infantile PKD.

    • This question is part of the following fields:

      • Endocrinology
      4.3
      Seconds

  • Question 11 - Where are ADH (vasopressin) and Oxytocin synthesised? ...

    Correct

    • Where are ADH (vasopressin) and Oxytocin synthesised?

      Your Answer: Hypothalamus

      Explanation:

      ADH and vasopressin are synthesized in the supraoptic and periventricular nuclei of the hypothalamus, they are eventually transported to the posterior pituitary where they are stored to be released later.

    • This question is part of the following fields:

      • Endocrinology
      5.5
      Seconds

  • Question 12 - What percentage of children does delayed puberty occur in? ...

    Correct

    • What percentage of children does delayed puberty occur in?

      Your Answer: 3%

      Explanation:

      Delayed puberty is defined as the absence of breast development in girls beyond the age of 13, and the absence of testicular development in boys beyond the age of 14. The incidence of delayed puberty is 3%, with the condition being more common in boys.

    • This question is part of the following fields:

      • Endocrinology
      5.5
      Seconds

  • Question 13 - Which of the following inhibit Glucagon? ...

    Incorrect

    • Which of the following inhibit Glucagon?

      Your Answer: Cholecystokinin

      Correct Answer: Uraemia

      Explanation:

      Glucagon release is inhibited by increased blood glucose, ketones, free fatty
      acids, insulin, raised urea levels and somatostatin. Glucagon is produced by alpha cells of the pancreas and increases the plasma glucose level by stimulating glycogenolysis and gluconeogenesis.

    • This question is part of the following fields:

      • Endocrinology
      23.7
      Seconds

  • Question 14 - What is the role of DHEA produced by the fetal adrenal glands? ...

    Incorrect

    • What is the role of DHEA produced by the fetal adrenal glands?

      Your Answer: Stimulate gonadal development of the foetus

      Correct Answer: Stimulate placenta to form oestrogen

      Explanation:

      Dehydroepiandrosterone (DHEA) is a steroid hormone synthesised from cholesterol (via Pregnenolone) by the adrenal glands. The foetus manufactures DHEA, which stimulates the placenta to form oestrogen, thus keeping a pregnancy going. Production of DHEA stops at birth, then begins again around age seven and peaks when a person is in their mid-20s

    • This question is part of the following fields:

      • Endocrinology
      10.4
      Seconds

  • Question 15 - High levels of alpha feto protein are found in all, EXCEPT? ...

    Incorrect

    • High levels of alpha feto protein are found in all, EXCEPT?

      Your Answer: Intrauterine fetal distress

      Correct Answer: Trisomy 21

      Explanation:

      Pregnant maternal serum AFP levels elevated: Neural tube defects (e.g., spina bifida, anencephaly); Omphalocele; Gastroschisis.

      Pregnant maternal serum AFP low levels: Down syndrome

    • This question is part of the following fields:

      • Endocrinology
      25
      Seconds

  • Question 16 - All of the following are autosomal recessive conditions EXCEPT which one? ...

    Incorrect

    • All of the following are autosomal recessive conditions EXCEPT which one?

      Your Answer: Sickle Cell

      Correct Answer: Osteogenesis Imperfecta

      Explanation:

      Osteogenesis imperfect is an autosomal dominant condition. All the rest of the options are autosomal recessive conditions.

    • This question is part of the following fields:

      • Endocrinology
      14.4
      Seconds

  • Question 17 - Delayed puberty in girls is defined as? ...

    Incorrect

    • Delayed puberty in girls is defined as?

      Your Answer: Primary amenorrhoea at age 14

      Correct Answer: Absence of breast development in girls beyond 13 years old

      Explanation:

      Breast development occurs from the age of 9-13 at the onset of puberty. Delayed puberty is defined as the absence of breast development after the age of 13.

    • This question is part of the following fields:

      • Endocrinology
      16.8
      Seconds

  • Question 18 - All of the following organs are involved in oestrogen production except: ...

    Incorrect

    • All of the following organs are involved in oestrogen production except:

      Your Answer: Adrenal glands

      Correct Answer: Anterior pituitary

      Explanation:

      Oestrogen can be produced by variety of organs including the corpus leuteum, placenta, adrenal glands and testes. However it is not produced by the anterior pituitary. The anterior pituitary produces LH and FSH which in turn causes oestrogen secretion.

    • This question is part of the following fields:

      • Endocrinology
      13.4
      Seconds

  • Question 19 - What is the definition of premature menopause? ...

    Correct

    • What is the definition of premature menopause?

      Your Answer: Menopause at or before 40 years of age

      Explanation:

      Menopause is defined as the cessation of menstruation for a period of 12 months. Premature menopause is defined as cessation of menstruation before the age of 40.

    • This question is part of the following fields:

      • Endocrinology
      8.2
      Seconds

  • Question 20 - Which of the following changes would you expect in pregnancy? ...

    Incorrect

    • Which of the following changes would you expect in pregnancy?

      Your Answer: Increased TSH, Increased Total T3 and T4

      Correct Answer: Decreased TSH Increased Total T3 and T4

      Explanation:

      Human chorionic gonadotrophin (hCG) has thyrotrophic activity owing to subunit homology with thyroid-stimulating hormone (TSH) and maternal TSH production is suppressed during the first trimester of pregnancy, when hCG levels are highest. The TSH response to thyrotrophin-releasing hormone (TRH) is reduced during the first trimester but returns to normal after this. Thyroid binding globulin increases in the first 2 weeks of pregnancy and reaches a plateau by 20 weeks. This leads to increased production of total T3 (tri-iodothyronine) and T4 (thyroxine).

    • This question is part of the following fields:

      • Endocrinology
      17.6
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Endocrinology (13/20) 65%
Passmed
Retry this test Dashboard