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  • Question 1 - Which of the following features do mast cells and basophils have in common:...

    Correct

    • Which of the following features do mast cells and basophils have in common:

      Your Answer: Are essential for immediate type-hypersensitivity reactions

      Explanation:

      Anaphylaxis is a severe immediate allergic reaction of rapid onset affecting many body systems. It is due to the release of inflammatory mediators and cytokines from mast cells and basophils. Basophils are the least common of the granulocytes, representing about 0.5 to 1% of circulating white blood cells. However, they are the largest type of granulocyte. They are responsible for inflammatory reactions during immune response, as well as in the formation of acute and chronic allergic diseases, including anaphylaxis, asthma, atopic dermatitis and hay fever. They can perform phagocytosis (cell eating), produce histamine and serotonin that induce inflammation, and heparin that prevents blood clotting. Mast cells are similar in appearance and function. Both cell types store histamine, a chemical that is secreted by the cells when stimulated.

    • This question is part of the following fields:

      • Immunology
      • Medicine
      13.1
      Seconds

  • Question 2 - Which is the primary lymphoid organ? ...

    Correct

    • Which is the primary lymphoid organ?

      Your Answer: Thymus

      Explanation:

      Lymphoid organs consist of lymph nodes, the thymus, spleen and tonsils. The thymus is the primary lymphoid organ as it is the organ in which the T cells mature.

    • This question is part of the following fields:

      • Immunology
      • Medicine
      1.8
      Seconds

  • Question 3 - Which cells are considered the source of IL-3? ...

    Correct

    • Which cells are considered the source of IL-3?

      Your Answer: T lymphocytes

      Explanation:

      IL-3 stimulates haematopoiesis and is secreted mainly from the T lymphocytes.

    • This question is part of the following fields:

      • Immunology
      • Medicine
      11.5
      Seconds

  • Question 4 - Amongst the following cells, which is responsible for the secretion of defensins? ...

    Correct

    • Amongst the following cells, which is responsible for the secretion of defensins?

      Your Answer: Neutrophils

      Explanation:

      Eosinophils are phagocytic and they are directed against helminths. Basophils are involved in allergic reactions and contain histamine and vasoactive granules in their cytoplasm. Mast cells are similar to basophils. Monocytes differentiate into macrophages in the tissue, secret interleukins and are phagocytic. Neutrophils are phagocytic but are also responsible for secreting defensins.

    • This question is part of the following fields:

      • Immunology
      • Medicine
      4.2
      Seconds

  • Question 5 - Humoral immunity is a major defence against: ...

    Correct

    • Humoral immunity is a major defence against:

      Your Answer: Viral infections

      Explanation:

      Humoral immunity is provided by the neutralizing and non-neutralizing antibodies that are formed from the B lymphocytes. This form of immunity is most important in viral infection. Non-neutralizing antibodies increases phagocytosis of the infected cell and inhibit the ability of the virus to replicate.

    • This question is part of the following fields:

      • Immunology
      • Medicine
      4.9
      Seconds

  • Question 6 - Cell mediating innate immunity include: ...

    Correct

    • Cell mediating innate immunity include:

      Your Answer: Natural killer cells

      Explanation:

      Antigen receptors recognize the shape of the antigen. They identify specific epitopes and are found on T cells.

    • This question is part of the following fields:

      • Immunology
      • Medicine
      4.7
      Seconds

  • Question 7 - Which immunological cells are predominant in the lymph node (almost 98 % residence)?...

    Correct

    • Which immunological cells are predominant in the lymph node (almost 98 % residence)?

      Your Answer: Lymphocytes

      Explanation:

      Lymph nodes are a lymphoid organ mostly consisting of lymphocytes: B cells in the cortex from where they mature and proliferate and T cells in the paracortex. The medulla is also composed of lymphocytes and macrophages.

    • This question is part of the following fields:

      • Immunology
      • Medicine
      5.8
      Seconds

  • Question 8 - The predominant site in the lymph node where B lymphocytes are found is:...

    Correct

    • The predominant site in the lymph node where B lymphocytes are found is:

      Your Answer: Cortex

      Explanation:

      The cortex of the lymph node consists of the lymphoid nodules and sinusoids and posses a germinal centre from which B cells proliferate. The cortex of the lymph node predominately consists of B cells.

    • This question is part of the following fields:

      • Immunology
      • Medicine
      7
      Seconds

  • Question 9 - The collection of genes that are termed the major histocompatibility complex (MHC) are...

    Correct

    • The collection of genes that are termed the major histocompatibility complex (MHC) are found on:

      Your Answer: Short arm of chromosome 6

      Explanation:

      Histocompatibility, or tissue compatibility, is the property of having the same, or sufficiently similar, alleles of a set of genes called human leukocyte antigens (HLA). HLA is the human form of the major histocompatibility complex (MHC) genes found in all vertebrates. On a population level there is a great number of different alleles at each HLA locus on the short arm of chromosome 6

    • This question is part of the following fields:

      • Immunology
      • Medicine
      3.6
      Seconds

  • Question 10 - The cytoplasmic form of superoxide dismutase [SOD] contains: ...

    Correct

    • The cytoplasmic form of superoxide dismutase [SOD] contains:

      Your Answer: Zn and Cu

      Explanation:

      The cytoplasmic form of superoxide dismutase [SOD] contains zinc and copper

    • This question is part of the following fields:

      • Immunology
      • Medicine
      1.9
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Immunology (10/10) 100%
Medicine (10/10) 100%
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