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  • Question 1 - Rhesus D immunoglobin treatment utilises what class of antibody? ...

    Incorrect

    • Rhesus D immunoglobin treatment utilises what class of antibody?

      Your Answer: IgE

      Correct Answer: IgG

      Explanation:

      It utilizes the IgG class of the antibody.

    • This question is part of the following fields:

      • Immunology
      7.2
      Seconds

  • Question 2 - Which Immunoglobulin (or antibody) is secreted in large amounts in breast milk? ...

    Incorrect

    • Which Immunoglobulin (or antibody) is secreted in large amounts in breast milk?

      Your Answer: IgD

      Correct Answer: IgA

      Explanation:

      The major constituents of breast milk are lactose, protein, fat and water. However, the composition of breast milk is not constant; early lactation differs from late lactation, one feed differs from the next, and the composition can even change
      during a feed. Artificial infant formulas cannot therefore be identical to breast milk. In addition to IgA, breast milk contains small amounts of IgM and IgG and other factors such as lactoferrin, macrophages, complement and lysozymes

    • This question is part of the following fields:

      • Immunology
      1
      Seconds

  • Question 3 - The Mantoux test utilises what type of hypersensitivity reaction? ...

    Incorrect

    • The Mantoux test utilises what type of hypersensitivity reaction?

      Your Answer: Type II

      Correct Answer: Type IV

      Explanation:

      The Mantoux test is based on type IV hypersensitivity reaction.

    • This question is part of the following fields:

      • Immunology
      6.5
      Seconds

  • Question 4 - To avoid potential haemolysis, Anti D immunoglobulin should be administered to which of...

    Correct

    • To avoid potential haemolysis, Anti D immunoglobulin should be administered to which of the following?

      Your Answer: Rhesus negative mother, non-sensitised, fetal cord blood Rh positive

      Explanation:

      The Rhesus status of a mother is important in pregnancy and even abortion. The exposure of an Rh-negative mother exposed to Rh antigens from a positive foetus, will influence the development of anti-Rh antibodies. This may cause problems in subsequent pregnancies leading to haemolysis in the newborn. Rh Anti RhD- globulin is therefore given to non-sensitised Rh-negative mothers who give birth to Rh-positive children to prevent the formation of anti-Rh antibodies. Anti RhD globulin is not useful for already sensitized, or RhD positive mothers; its administration could result in maternal blood being bound and taken out of circulation.

    • This question is part of the following fields:

      • Immunology
      64.3
      Seconds

  • Question 5 - You see a patient in antenatal clinic who is concerned that she has...

    Correct

    • You see a patient in antenatal clinic who is concerned that she has never had chicken pox and may catch it during pregnancy. You check her Varicella status and she is non-immune. She asks you about vaccination. What type of vaccine is the varicella vaccine?

      Your Answer: Attenuated

      Explanation:

      Varicella is a live vaccine. The recent RCOG green top guidelines suggest vaccine can be considered postpartum or pre pregnancy but NOT whilst pregnant. In the non-immune pregnant woman they should be advised to avoid contact with people with chickenpox or shingles and to contact a healthcare professional promptly if exposed. If they have a significant exposure VZIG should be offered as soon as possible.

    • This question is part of the following fields:

      • Immunology
      19.3
      Seconds

  • Question 6 - Fetal immunoglobulin production begins at what gestation? ...

    Correct

    • Fetal immunoglobulin production begins at what gestation?

      Your Answer: Week 10

      Explanation:

      Fetal production of immunoglobulin begins early on, at about 10 weeks gestation with the production of IgM antibodies. Maternal IgG, which is a key component of fetal immunity, is passed on to the foetus through the placenta from 12 weeks of gestation. Secretory IgA is not produced until after birth.

    • This question is part of the following fields:

      • Immunology
      27.4
      Seconds

  • Question 7 - Which immunoglobulin is the first to be synthesised by the neonate? ...

    Correct

    • Which immunoglobulin is the first to be synthesised by the neonate?

      Your Answer: IgM

      Explanation:

      Fetal production of immunoglobulin begins early on at about 10 weeks gestation with the production of IgM antibodies. Maternal IgG, which is a key component of fetal immunity is passed on to the foetus through the placenta from 12 weeks of gestation. Secretory IgA is not produced until after birth, through breast milk.

    • This question is part of the following fields:

      • Immunology
      12.2
      Seconds

  • Question 8 - Which of the following will require Anti-D administration post partum? ...

    Correct

    • Which of the following will require Anti-D administration post partum?

      Your Answer: Rhesus negative mother, non-sensitised, fetal cord blood Rh positive

      Explanation:

      Rhesus positive mothers should not get anti-D. They have Rhesus antigens and the anti-D would result in maternal blood being bound and removed from her circulation. The danger is to children born to mothers who are rhesus negative. As the mother may develop antibodies against Rhesus positive fetal blood. Therefore if the baby is Rhesus negative then there is no risk of alloimmunisation (sensitisation)

    • This question is part of the following fields:

      • Immunology
      37.5
      Seconds

  • Question 9 - You have just clerked in a patient on the labour ward who has...

    Incorrect

    • You have just clerked in a patient on the labour ward who has SLE. What type of hypersensitivity reaction is SLE an example of?

      Your Answer: Type IV

      Correct Answer: Type III

      Explanation:

      SLE is a type III hypersensitivity reaction

    • This question is part of the following fields:

      • Immunology
      29.8
      Seconds

  • Question 10 - Macrophages are derived from what type of white blood cell? ...

    Correct

    • Macrophages are derived from what type of white blood cell?

      Your Answer: Monocytes

      Explanation:

      Macrophages are derived from monocytes. When monocytes come across a pathogen they differentiate into macrophages for phagocytosis to occur.

    • This question is part of the following fields:

      • Immunology
      3.8
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Immunology (8/10) 80%
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