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  • Question 1 - If a catheter is placed in the main pulmonary artery of a healthy...

    Incorrect

    • If a catheter is placed in the main pulmonary artery of a healthy 30-year-old woman, which of the following will be its mean pulmonary arterial pressure?

      Your Answer: 10 mmHg

      Correct Answer: 15 mmHg

      Explanation:

      The pulmonary artery pressure (PA pressure) is a measure of the blood pressure found in the main pulmonary artery. The hydrostatic pressure of the pulmonary circulation refers to the actual pressure inside pulmonary vessels relative to atmospheric pressure. Hydrostatic (blood pressure) in the pulmonary vascular bed is low compared with that of similar systemic vessels. The mean pulmonary arterial pressure is about 15 mmHg (ranging from about 13 to 19 mmHg) and is much lower than the average systemic arterial pressure of 90 mmHg.

    • This question is part of the following fields:

      • Physiology
      • Respiratory
      11.6
      Seconds
  • Question 2 - What is the percentage of bone calcium that is freely exchangeable with the...

    Correct

    • What is the percentage of bone calcium that is freely exchangeable with the extracellular fluid that is available for buffering changes in the calcium ion balance?

      Your Answer: 1%

      Explanation:

      Around 1% of calcium in the body is available for buffering changes in calcium ion balance. These are mainly derived from the bone that are freely exchangeable with extracellular fluid.

    • This question is part of the following fields:

      • Fluids & Electrolytes
      • Pathology
      8.5
      Seconds
  • Question 3 - A 14 year-old girl is found to have haemophilia B. What pathological problem...

    Correct

    • A 14 year-old girl is found to have haemophilia B. What pathological problem does she have?

      Your Answer: Deficiency of factor IX

      Explanation:

      Haemophilia B (also known as Christmas disease) is due to a deficiency in factor IX. Haemophilia A is due to a deficiency in factor VIII.

    • This question is part of the following fields:

      • Haematology
      • Pathology
      4.6
      Seconds
  • Question 4 - Regarding the posterior compartment of the leg, which is correct? ...

    Correct

    • Regarding the posterior compartment of the leg, which is correct?

      Your Answer: The muscles plantarflex the foot and are innervated by the tibial nerve

      Explanation:

      The muscles of the back of the leg are subdivided into two groups: superficial and deep. Superficial muscles include gastrocnemius, soleus and plantaris. Deep muscles include tibialis posterior, flexor hallucis longus, flexor digitorum longus and popliteus. The superficial ( calf muscles) which are responsible for plantarflexion of the foot are supplied by the tibial nerve as follows: the gastrocnemius and soleus muscles are supplied by the first and second sacral nerves and the plantaris by the fourth and fifth lumbar and first sacral nerve (the tibial nerve).

    • This question is part of the following fields:

      • Anatomy
      • Lower Limb
      9.4
      Seconds
  • Question 5 - During pregnancy the uterus enlarges however after delivery it regresses to its original...

    Correct

    • During pregnancy the uterus enlarges however after delivery it regresses to its original size. Which of the following organelles is responsible for this regression?

      Your Answer: Lysosomes

      Explanation:

      Lysosomes are formed by budding of the Golgi apparatus and contain enzymes which digest macromolecules. They are found in both plants and animals and are active in autophagic cell death, digestion after phagocytosis and for the cells own recycling process. They fuse with the molecules and release their content resulting in digestion.

    • This question is part of the following fields:

      • General
      • Physiology
      4.4
      Seconds
  • Question 6 - An episiotomy is indicated for a woman during a difficult vaginal delivery. Whilst...

    Correct

    • An episiotomy is indicated for a woman during a difficult vaginal delivery. Whilst the registrar was performing this procedure she made a median cut too far through the perineal body cutting the structure immediately posterior. Which structure is this?

      Your Answer: External anal sphincter

      Explanation:

      An episiotomy is an incision that is made whenever there is a risk of a tear during vaginal deliver. A posterolateral incision, as opposed to a median incision is preferred. Of the options given, the external anal sphincter lies right posterior to the perineal body. The sacrospinous and the sacrotuberous ligaments are deep in the perineum that they should not be involved in this.

    • This question is part of the following fields:

      • Anatomy
      • Pelvis
      8.8
      Seconds
  • Question 7 - Which cells are most commonly seen in a granulomatous lesion that suggests an...

    Correct

    • Which cells are most commonly seen in a granulomatous lesion that suggests an underlying chronic inflammation?

      Your Answer: Lymphocytes

      Explanation:

      Lymphocytes and monocytes are commonly and characteristically recognised in a case of chronic inflammation.

      Eosinophils and neutrophils are seen with acute inflammation.

      Mast cells release histamine in early inflammation.

      Basophils are seen with allergies.

      Plasma cells are seen with viral infection.

      Platelets are not characteristic of any type of inflammation.

    • This question is part of the following fields:

      • Inflammation & Immunology
      • Pathology
      4.9
      Seconds
  • Question 8 - A 60-year old man with a left-sided indirect inguinal hernia underwent emergency surgery...

    Correct

    • A 60-year old man with a left-sided indirect inguinal hernia underwent emergency surgery to relieve large bowel obstruction resulting from a segment of the bowel being strangulated in the hernial sac. The most likely intestinal segment involved is:

      Your Answer: Sigmoid colon

      Explanation:

      The sigmoid colon is the most likely segment involved as it is mobile due to the presence of the sigmoid mesocolon. The descending colon, although on the left side, is a bit superior and is also retroperitoneal. The ascending colon and caecum are on the right side of the abdomen. The rectum is too inferior to enter the deep inguinal ring and the transverse colon is too superior to be involved.

    • This question is part of the following fields:

      • Abdomen
      • Anatomy
      20.2
      Seconds
  • Question 9 - After severe injury of the upper limb following an accident. The humerus is...

    Correct

    • After severe injury of the upper limb following an accident. The humerus is injured as well as the nerve which innervates the muscles of the anterior compartment of the arm. Which nerve is injured?

      Your Answer: Musculocutaneous

      Explanation:

      The musculoskeletal nerve supplies the muscles of the anterior compartment of the arm including the coracobrachialis, biceps brachii and the greater part of the brachialis. This nerve derives its fibres from the fifth, sixth and seventh cervical nerves and arises from the lateral cord of the brachial plexus. It also provides a branch to the elbow joint.

    • This question is part of the following fields:

      • Anatomy
      • Upper Limb
      13.7
      Seconds
  • Question 10 - Which of the following is a fact worth noting about the development of...

    Correct

    • Which of the following is a fact worth noting about the development of the spleen?

      Your Answer: It develops in the dorsal mesogastrium

      Explanation:

      The spleen in the human embryo arises in week 5 of intrauterine life. It appears as a proliferating mesenchyme above the pancreas. The spleen is one the organs that develops in the dorsal mesogastrium. When the stomach changes its position during development, the spleen is made to move behind the stomach and stays in contact with the left kidney. The spleen is found within the peritoneum of the abdominal cavity thus it is an intraperitoneal organ.

    • This question is part of the following fields:

      • Abdomen
      • Anatomy
      6.9
      Seconds
  • Question 11 - Regarding abduction of the digits of the hand, which of the following is...

    Correct

    • Regarding abduction of the digits of the hand, which of the following is correct?

      Your Answer: All of the adductors of the digits take at least part of their attachments from metacarpal bones

      Explanation:

      Lying on the palmer surfaces of the metacarpal bones are four palmar interossei which are smaller than the dorsal interossei. Arising from the entire length of the metacarpal bone of one finger, is a palmar interosseous, which is inserted into the side of the base of the first phalanx and the aponeurotic expansion of the extensor digitorum communis tendon to the same finger. All the interossei are innervated by the eighth cervical nerve, through the deep palmar branch of the ulnar nerve. The palmar interossei adducts the fingers to an imaginary line drawn longitudinally through the centre of the middle finger.

    • This question is part of the following fields:

      • Anatomy
      • Upper Limb
      22.4
      Seconds
  • Question 12 - What is the most likely cause of prolonged bleeding time in a 40...

    Incorrect

    • What is the most likely cause of prolonged bleeding time in a 40 year old women admitted for a laparoscopic cholecystectomy?

      Your Answer: Haemophilia

      Correct Answer: Thrombocytopaenia

      Explanation:

      Bleeding time is related to platelet function, thus a decrease in platelet function, as seen in thrombocytopenia, DIC and von Willebrand disease in which platelet aggregation is defective, leads to an increase in bleeding time. It is not affected by a decrease or deficiency of any other clotting factors. Aspirin and other COX inhibitors prolong bleeding time along with warfarin and heparin.

    • This question is part of the following fields:

      • General
      • Physiology
      18.1
      Seconds
  • Question 13 - A lady presents to the out patient clinic with a painful boil on...

    Incorrect

    • A lady presents to the out patient clinic with a painful boil on the skin of her mons pubis. Which nerve supplies the skin of the mons pubis?

      Your Answer: Ilioinguinal

      Correct Answer: Anterior labial

      Explanation:

      Anterior labial branch is the terminal branch of the ilioinguinal nerve that innervates the skin of the mons pubis in women and the skin of the anterior scrotum in men.

      The femoral branch of genitofemoral nerve innervates the upper medial thigh.

      The iliohypogastric innervates muscles of the abdominal wall.

      The subcostal nerve innervates muscles of the abdominal wall and the skin of the lower abdominal wall.

    • This question is part of the following fields:

      • Abdomen
      • Anatomy
      14.3
      Seconds
  • Question 14 - A CT scan of 65 year old male patient at an outpatient clinic...

    Correct

    • A CT scan of 65 year old male patient at an outpatient clinic suggested a bone tumour at the stylomastoid foramen. Which of the following cranial nerves is likely to be affected with this tumour?

      Your Answer: VII

      Explanation:

      Cranial nerve VII, the facial nerve, is found in the internal acoustic canal and runs through this canal into the facial canal before exiting through the stylomastoid foramen. In the case of a bone tumour at the stylomastoid process, the facial nerve is the nerve that will most likely be affected.

    • This question is part of the following fields:

      • Anatomy
      • Head & Neck
      16.9
      Seconds
  • Question 15 - The superior pancreaticoduodenal artery, the artery that supplies blood to the pancreas and...

    Incorrect

    • The superior pancreaticoduodenal artery, the artery that supplies blood to the pancreas and the duodenum, is a branch of the:

      Your Answer: Coeliac artery

      Correct Answer: Gastroduodenal artery

      Explanation:

      The superior pancreaticoduodenal artery together with the right gastroepiploic artery form the two branches of the gastroduodenal artery which divides at the lower border of the duodenum.

    • This question is part of the following fields:

      • Abdomen
      • Anatomy
      20.7
      Seconds
  • Question 16 - A 60 year-old patient being treated for hypertension presents to the ED with...

    Correct

    • A 60 year-old patient being treated for hypertension presents to the ED with swelling of the left upper limb due to poor venous return. On examination, it is found that an aneurysm of the ascending aorta is impinging on a large vein lying immediately anterosuperior to it. Which vein is it likely to be?

      Your Answer: Left brachiocephalic

      Explanation:

      Among the veins listed, only the left brachiocephalic vein is anterosuperior to the ascending aorta. The right brachiocephalic vein being on the right side would not be affected by the aortic aneurysm.

      The azygos vein lies deep in the chest on the right side.

      The internal thoracic vein lies interior to the anterior wall of the chest.

      The left superior intercostal vein is close to the aortic arch, crossing it laterally. This vein drains the 2nd to 4th interspaces on the left side.

      The Right internal jugular vein joins the right brachiocephalic vein which would not be affected by the aneurysm.

    • This question is part of the following fields:

      • Anatomy
      • Thorax
      21.4
      Seconds
  • Question 17 - During gastrectomy, the operating surgeon ligates the short gastric arteries along the greater...

    Correct

    • During gastrectomy, the operating surgeon ligates the short gastric arteries along the greater curvature of the stomach. Where do the short gastric arteries branch from?

      Your Answer: Splenic artery

      Explanation:

      Short gastric arteries arise from the splenic artery at the end or from its terminal divisions. They are about 5 or 7 in number, passing from the left to the right in between the layers of the gastrosplenic ligament to be distributed along the greater curvature of the stomach.

    • This question is part of the following fields:

      • Abdomen
      • Anatomy
      6.5
      Seconds
  • Question 18 - Carbachol is a cholinergic agonist. In which of these cases should carbachol be...

    Correct

    • Carbachol is a cholinergic agonist. In which of these cases should carbachol be administered?

      Your Answer: Cataract surgery

      Explanation:

      Carbachol (carbamylcholine) is a cholinergic agent, a choline ester and a positively charged quaternary ammonium compound. It is primarily used for various ophthalmic purposes, such as for treating glaucoma, or for use during ophthalmic surgery. It is usually administered topically to the eye or through intraocular injection. It is not well absorbed in the gastro-intestinal tract and does not cross the blood–brain barrier.

    • This question is part of the following fields:

      • Pathology
      • Pharmacology
      28.9
      Seconds
  • Question 19 - A lesion involving the lateral geniculate nucleus of the thalamus is likely to...

    Correct

    • A lesion involving the lateral geniculate nucleus of the thalamus is likely to affect:

      Your Answer: Vision

      Explanation:

      The lateral geniculate nucleus (LGN) of the thalamus is the primary processor of visual information in the central nervous system. The LGN receives information directly from the retina and sends projections directly to the primary visual cortex. The LGN likely helps the visual system focus its attention on the most important information.

    • This question is part of the following fields:

      • Neurology
      • Physiology
      5.1
      Seconds
  • Question 20 - A patient who following 20 years of working in the asbestos industry develops...

    Correct

    • A patient who following 20 years of working in the asbestos industry develops malignant mesothelioma and is scheduled for pleuropneumonectomy to remove the entire pleura and lung on the affected side. Which layer would provide a natural cleavage plane for surgical separation of the costal pleura from the thoracic wall?

      Your Answer: Endothoracic fascia

      Explanation:

      The endothoracic fascia is connective tissue that is between the costal parietal pleura and the inner aspect of the chest wall. Removing this layer of connective tissue would make it easy to separate the costal pleura from the thoracic wall.

      Deep fascia: is not found around the lungs. It is a layer of connective tissue that invests a muscle or a group of muscles.

      Parietal pleura: part of the pleura that lines the inner surface of the chest/thoracic cavity.

      Visceral pleura: is the serous membrane that lines the surface of the lungs.

      Transversus thoracis muscle fascia is associated only with the muscle transversus thoracis.

      Peritracheal fascia: a layer of connective tissue that invests the trachea. It is not associated with the thoracic wall or the costal pleura.

    • This question is part of the following fields:

      • Anatomy
      • Thorax
      8
      Seconds
  • Question 21 - Purkinje fibres in the heart conduct action potentials at the rate of: ...

    Incorrect

    • Purkinje fibres in the heart conduct action potentials at the rate of:

      Your Answer: 5.0–8.5 m/s

      Correct Answer: 1.5–4.0 m/s

      Explanation:

      Purkinje fibres control the heart rate along with the sinoatrial node (SA node) and the atrioventricular node (AV node). The QRS complex is associated with the impulse passing through the Purkinje fibres. These fibres conduct action potential about six times faster than the velocity in normal cardiac muscle.

    • This question is part of the following fields:

      • Cardiovascular
      • Physiology
      7.9
      Seconds
  • Question 22 - Chronic obstructive pulmonary disease (COPD) is likely to result in: ...

    Correct

    • Chronic obstructive pulmonary disease (COPD) is likely to result in:

      Your Answer: Respiratory acidosis

      Explanation:

      COPD leads to respiratory acidosis (chronic). This occurs due to hypoventilation which involves multiple causes, such as poor responsiveness to hypoxia and hypercapnia, increased ventilation/perfusion mismatch leading to increased dead space ventilation and decreased diaphragm function.

    • This question is part of the following fields:

      • Physiology
      • Respiratory
      6.9
      Seconds
  • Question 23 - Where would you insert the needle when drawing blood from a patient's median...

    Correct

    • Where would you insert the needle when drawing blood from a patient's median cubital vein?

      Your Answer: Anterior aspect of the elbow

      Explanation:

      The correct answer is to insert it into the anterior aspect of the elbow. If you look at the venous drainage of the upper limb, you will find that there are two main veins, the basilic and the cephalic vein; the connecting branch between these two veins is the median cubital vein. and this vein passes via the cubital fossa which is on the anterior aspect of the forearm.

    • This question is part of the following fields:

      • Anatomy
      • Upper Limb
      19.5
      Seconds
  • Question 24 - Which of the following organelles have the capacity to regenerate and spontaneously replicate?...

    Correct

    • Which of the following organelles have the capacity to regenerate and spontaneously replicate?

      Your Answer: Mitochondrion

      Explanation:

      A mitochondria is a membrane bound organelle found in eukaryotic cells. They are called the powerhouse of the cell and are the place where ATP is formed from energy generated through metabolism. They are capable of replication as well as repair and regeneration.

    • This question is part of the following fields:

      • General
      • Physiology
      3.5
      Seconds
  • Question 25 - A 44-year old man, who was euthyroid underwent thyroidectomy following neoplastic cells found...

    Incorrect

    • A 44-year old man, who was euthyroid underwent thyroidectomy following neoplastic cells found on fine-needle aspiration. Frozen section of multiple thyroid masses showed malignant neoplasm of polygonal cells in nests. The neoplasm also showed presence of amyloid which was positive with Congo-red staining. Immunoperoxidase staining for calcitonin was also positive. Chest X-ray revealed no abnormality. However, his blood pressure was found to be raised, and his serum ionised calcium was high. What is the likely diagnosis?

      Your Answer: Multiple endocrine neoplasia type IIB

      Correct Answer: Multiple endocrine neoplasia type IIA

      Explanation:

      MEN (Multiple Endocrine Neoplasia) syndromes are a group of three separate familial disease which consists of adenomatous hyperplasia and neoplasia in several endocrine glands. All three conditions are inherited as an autosomal dominant trait, with a single gene producing multiple effects. MEN IIA is characterized by medullary carcinoma of the thyroid, pheochromocytoma and hyperparathyroidism. It should be suspected in patients with bilateral pheochromocytoma, a familial history of MEN, or at least two characteristic endocrine manifestations. Genetic testing is used to confirm the diagnosis. Early diagnosis is crucial to aid in complete excision of the localized tumour. Pheochromocytomas can be detected by plasma free metanephrines and fractionated urinary catecholamines, particularly adrenaline (epinephrine).

      Imaging studies such as computed tomography or magnetic resonance imaging might also prove useful. Hyperparathyroidism is diagnosed by the standard finding of hypercalcaemia, hypophosphatemia and an increased parathyroid hormone level. Once MEN IIA syndrome is identified in any patient, it is recommended that his or her first-degree relatives and any other symptomatic also undergo genetic testing. Relatives should be subjected to annual screening for hyperparathyroidism and pheochromocytoma beginning in early childhood and continue indefinitely. Serum calcium levels help in screening for hyperparathyroidism. Similarly, screening for pheochromocytoma is by history, measurement of the blood pressure and laboratory testing.

    • This question is part of the following fields:

      • Endocrine
      • Pathology
      105.7
      Seconds
  • Question 26 - Which of the following key features will be seen in an organ undergoing...

    Correct

    • Which of the following key features will be seen in an organ undergoing atrophy?

      Your Answer: A greater number of autophagic vacuoles

      Explanation:

      Atrophy is characterised by the breakdown of intracellular components along with organelles and packing them into vacuoles known as autophagic vacuoles. This is an adaptive response that separates the damaged cellular structures from the rest of the cells.

    • This question is part of the following fields:

      • Cell Injury & Wound Healing
      • Pathology
      1.3
      Seconds
  • Question 27 - Skin infiltration by neoplastic T lymphocytes is seen in: ...

    Correct

    • Skin infiltration by neoplastic T lymphocytes is seen in:

      Your Answer: Mycosis fungoides

      Explanation:

      Mycosis fungoides is a chronic T-cell lymphoma that involves the skin and less commonly, the internal organs such as nodes, liver, spleen and lungs. It is usually diagnosed in patients above 50 years and the average life expectancy is 7-10 years. It is insidious in onset and presents as a chronic, itchy rash, eventually spreading to involve most of the skin. Lesions are commonly plaque-like, but can be nodular or ulcerated. Symptoms include fever, night sweats and weight loss. Skin biopsy is diagnostic. However, early cases may pose a challenge due to fewer lymphoma cells. The malignant cells are mature T cells (T4+, T11+, T12+). The epidermis shows presence of characteristic Pautrier’s micro abscesses are present in the epidermis.

    • This question is part of the following fields:

      • Haematology
      • Pathology
      2.5
      Seconds
  • Question 28 - A 42 year old women presents with end stage renal failure and is...

    Correct

    • A 42 year old women presents with end stage renal failure and is prepared to receive a kidney from her husband. HLA testing showed that they are not a 100% match and she is given immunosuppressant therapy for this. Three months later when her renal function tests were performed she showed signs of deteriorating renal function, with decreased renal output, proteinuria of +++ and RBCs in the urine. She was given antilymphocyte globulins and her condition reversed. What type of graft did this patient receive?

      Your Answer: Allograft

      Explanation:

      Allograft describes a graft between two of the same species. As the donor and the recipients are history-incompatible, rejection of the graft is common and is controlled by immunosuppressive drug therapy. Isograft and syngraft are synonymous and referred to a graft transferred between genetically identical individuals e.g. identical twins. In this case rejection is rare as they are history-compatible.

      Autograft refers to transfer of one part of the body to another location.

      Xenograft is transfer of tissue from another species e.g. pig to human in valve replacement surgeries and rejection is very high.

    • This question is part of the following fields:

      • Inflammation & Immunology; Renal
      • Pathology
      20.1
      Seconds
  • Question 29 - Which tumour site is more commonly involved in adults than in children? ...

    Correct

    • Which tumour site is more commonly involved in adults than in children?

      Your Answer: Lung

      Explanation:

      In adults, the most common primary site of tumour is in the lungs, compared to children wherein the most common primary site is the blood.

    • This question is part of the following fields:

      • Neoplasia
      • Pathology
      13
      Seconds
  • Question 30 - During an operation to repair an aortic coarctation in a neonate, a surgeon...

    Incorrect

    • During an operation to repair an aortic coarctation in a neonate, a surgeon accidentally cuts the first aortic intercostal arteries as he mobilised the descending aorta. Which one of the following structure might be deprived of its primary source of blood supply following this injury?

      Your Answer: First posterior intercostal space

      Correct Answer: Right bronchus

      Explanation:

      The right bronchus is supplied by one right bronchial artery that may branch from one of the left bronchial arteries or from the right 3rd posterior intercostal artery (this is the first intercostal artery that arises from the aorta). Damage to this artery might stop blood supply to the main bronchus. Intercostal arteries that go to the first and the second interspaces originate from the highest intercostal artery such that blood supply to either of these spaces would not be interfered with.

      The left bronchus receives blood from 2 left bronchial arteries which are direct branches from the descending aorta.

      Fibrous pericardium is the sac that contains the heart. Its blood supply is not a major concern.

      Visceral pericardium receives its blood supply from the coronary vessels.

    • This question is part of the following fields:

      • Anatomy
      • Thorax
      16.2
      Seconds
  • Question 31 - What will the destruction of endoplasmic reticulum stop? ...

    Correct

    • What will the destruction of endoplasmic reticulum stop?

      Your Answer: Synthesis of proteins

      Explanation:

      The rough endoplasmic reticulum is the factory for the manufacturing of proteins. It contains ribosomes attached to it and transports proteins that are destined for membranes and secretions. The rough ER is connected to the nuclear envelope and to the cisternae of the Golgi apparatus by vesicles that shuttle between the two compartments.

    • This question is part of the following fields:

      • General
      • Physiology
      4.9
      Seconds
  • Question 32 - All the following statements are FALSE regarding the ophthalmic division of the trigeminal...

    Incorrect

    • All the following statements are FALSE regarding the ophthalmic division of the trigeminal nerve, except:

      Your Answer: It passes through the inferior orbital fissure

      Correct Answer: The ophthalmic nerve is the smallest branch of the trigeminal nerve

      Explanation:

      The ophthalmic nerve is the smallest of the three trigeminal divisions. The cutaneous branches of the ophthalmic nerve supply the conjunctiva, the skin over the forehead, the upper eyelid, and much of the external surface of the nose.

    • This question is part of the following fields:

      • Anatomy
      • Head & Neck
      22
      Seconds
  • Question 33 - A previously healthy 40-year-old housewife suddenly complains of a headache and loses consciousness....

    Correct

    • A previously healthy 40-year-old housewife suddenly complains of a headache and loses consciousness. A CT scan reveals subarachnoid haemorrhage. Which of the following is the most probable cause?

      Your Answer: Ruptured berry aneurysm

      Explanation:

      Saccular aneurysms, also known as berry aneurysms, appear as a round outpouching and are the most common form of cerebral aneurysm. They are a congenital intracranial defect, and haemorrhage can occur at any age, but is most common between the ages of 40-65 years. A second rupture (rebleeding) sometimes occurs, most often within about 7 days of the first bleed.

    • This question is part of the following fields:

      • Neurology
      • Pathology
      7.4
      Seconds
  • Question 34 - In which of the following conditions will the oxygen-haemoglobin dissociation curve shift to...

    Correct

    • In which of the following conditions will the oxygen-haemoglobin dissociation curve shift to the right?

      Your Answer: Exercise

      Explanation:

      The oxygen-haemoglobin dissociation curve plots saturated haemoglobin against the oxygen tension and is usually a sigmoid plot. Each molecule of haemoglobin can bind to four molecules of oxygen reversibly. Factors that can influence the binding include: pH, concentration of 2,3-diphosphoglycerate (2,3-DPG), temperature, type of haemoglobin molecules, and presence of toxins, especially carbon monoxide. Shape of the curve is due to interaction of bound oxygen molecules with the incoming molecules. The binding of first molecule is difficult, with easier binding of the second and third molecule and increase in difficulty with the fourth molecule – partly as a result of crowding and partly as a natural tendency of oxygen to dissociate.

      Left shift of curve indicates haemoglobin’s increased affinity for oxygen (seen at lungs). Right shift indicates decreased affinity and is seen with an increase in body temperature, hydrogen ions, 2,3-diphosphoglycerate (DPG), carbon dioxide concentration and exercise. Under normal resting conditions in a healthy individual, the normal position of the curve is at a pH of 7.4. A shift in the position of the curve with a change in pH is called the Bohr effect. Left shift occurs in acute alkalosis, decrease in p(CO2), decrease in temperature and decrease in 2,3-DPG. The fetal haemoglobin curve is to the left of the adult haemoglobin to allow for oxygen diffusion across the placenta. The curve for myoglobin is even further to the left. Carbon monoxide has a much higher affinity for haemoglobin than oxygen does. Thus, carbon monoxide poisoning leads to hypoxia.

    • This question is part of the following fields:

      • Physiology
      • Respiratory
      3.5
      Seconds
  • Question 35 - Which lymph nodes are most likely to enlarge due to the spread of...

    Correct

    • Which lymph nodes are most likely to enlarge due to the spread of infection through the lymphatic channels in a patient with a boil on his scrotum?

      Your Answer: Superficial inguinal nodes

      Explanation:

      The superficial inguinal nodes drain the perineum and the external genitalia which include the scrotum and the labia majora. The testes, however, drain to the lumbar nodes.

    • This question is part of the following fields:

      • Anatomy
      • Pelvis
      4
      Seconds
  • Question 36 - The majority of gallstones are mainly composed of: ...

    Correct

    • The majority of gallstones are mainly composed of:

      Your Answer: Cholesterol

      Explanation:

      Bile salts are formed out of cholesterol in the liver cells. Occasionally, precipitation of cholesterol occurs resulting into cholesterol stones developing in the gall bladder.

      These cholesterol gallstones are the most common type and account for 80% of all gallstones. Another type, accounting for 20% gallstones is pigment stones which are composed of bilirubin and calcium salts. Occasionally, stones of mixed origin are also seen.

    • This question is part of the following fields:

      • Gastroenterology
      • Physiology
      2
      Seconds
  • Question 37 - Whilst snorkelling, a 30-year old gentleman has the respiratory rate of 10/min, tidal...

    Incorrect

    • Whilst snorkelling, a 30-year old gentleman has the respiratory rate of 10/min, tidal volume of 550 ml and an effective anatomical dead space of 250 ml. Which of the following will bring about a maximum increase in his alveolar ventilation?

      Your Answer: A 4x increase in tidal volume

      Correct Answer: A 2x increase in tidal volume and a shorter snorkel

      Explanation:

      Alveolar ventilation = respiratory rate × (tidal volume − anatomical dead space volume). Increase in respiratory rate simply causes movement of air in the anatomical dead space, with no contribution to the alveolar ventilation. By use of a shorter snorkel, the effective anatomical dead space will decrease and will cause a maximum rise in alveolar ventilation along with doubling of tidal volume.

    • This question is part of the following fields:

      • Physiology
      • Respiratory
      27.9
      Seconds
  • Question 38 - Which of the following is likely to result in hematocolpos in a 12-year...

    Correct

    • Which of the following is likely to result in hematocolpos in a 12-year old girl?

      Your Answer: Imperforate hymen

      Explanation:

      Hematocolpos means accumulation of blood in vagina and hematometra is accumulation of blood in the uterus. These are most likely seen with an imperforate hymen; which is seen I 1 in 2000 females. If spontaneous resolution does not occur, treatment involves making a hole in the hymen to allow discharge of menstrual blood.

    • This question is part of the following fields:

      • Pathology
      • Women's Health
      6.5
      Seconds
  • Question 39 - A terrorist running away from the police was shot in the back. The...

    Incorrect

    • A terrorist running away from the police was shot in the back. The bullet hit his left lung halfway between its apex and the diaphragmatic surface. Which part of the lung was most likely to be injured?

      Your Answer: Lingula

      Correct Answer: Inferior lobe

      Explanation:

      The oblique fissure of the left lung is so sharp that the posterior surface of the left lung is mostly composed of the inferior lobe so that the point halfway between the apex and the diaphragmatic surface of the lung would result in injury to the inferior lobe.

      The hilum is the point on the medial surface of the lung where the structures that form the root of the lung enter and leave the lung.

      The lingual on the other hand is part of the superior lobe of the left lung and it is part of the anterior and superior sides of the lung.

      The middle lobe is only found on the right lung.

    • This question is part of the following fields:

      • Anatomy
      • Thorax
      6.4
      Seconds
  • Question 40 - An infant, 5 weeks and 6 days old born with a large sub-aortic...

    Incorrect

    • An infant, 5 weeks and 6 days old born with a large sub-aortic ventricular septal defect, is prepared for pulmonary artery banding through a left thoracotomy (the child is not fit for a surgical closure). The surgeon initially passes his index finger immediately behind two great arteries in the pericardial sac to mobilise the great arteries in order to pass the tape around the pulmonary artery. Into which space is the surgeon's finger inserted?

      Your Answer: Oblique pericardial sinus

      Correct Answer: Transverse pericardial sinus

      Explanation:

      Cardiac notch: is an indentation on the left lung of the heart.

      Coronary sinus: a venous sinus on the surface of the heart (the posterior aspect) that receives blood from the smaller veins that drain the heart.

      Coronary sulcus: a groove on the heart between the atria and ventricles.

      Transverse pericardial sinus: located behind the aorta and pulmonary trunk and anterior to the superior vena cava.

      Oblique pericardial sinus: located behind the left atrium. Accessed from the inferior side (or the apex) of the heart upwards.

      Horizontal pericardial sinus: this is a made-up term.

    • This question is part of the following fields:

      • Anatomy
      • Thorax
      21.4
      Seconds
  • Question 41 - Action potentials are used extensively by the nervous system to communicate between neurones...

    Correct

    • Action potentials are used extensively by the nervous system to communicate between neurones and muscles or glands. What happens during the activation of a nerve cell membrane?

      Your Answer: Sodium ions flow inward

      Explanation:

      During the generation of an action potential, the membrane gets depolarized which cause the voltage gated sodium channels to open and sodium diffuses inside the neuron, resulting in the membrane potential moving towards a positive value. This positive potential will then open the voltage gated potassium channels and cause more K+ to move out decreasing the membrane potential and restoring the membrane potential to its resting value.

    • This question is part of the following fields:

      • General
      • Physiology
      9.1
      Seconds
  • Question 42 - A 60-year old gentleman visited his general practitioner complaining of high grade fever...

    Correct

    • A 60-year old gentleman visited his general practitioner complaining of high grade fever for 7 days and a dull, aching pain in his left lumbar region. On enquiry, he admitted to having a burning sensation while passing urine. His blood results showed an elevated white blood cell count with a left shift. In his condition, which is the most characteristic finding on urine examination?

      Your Answer: White blood cell casts

      Explanation:

      Tubulointerstitial nephritis is the term given to primary injury to renal tubules and the renal interstitium, which ultimately results in a decline in renal function. Acute tubulointerstitial nephritis (acute pyelonephritis) is often seen as a result of infection or drug reactions. The most characteristic feature of this condition on urine analysis is the presence of white blood cell casts.

    • This question is part of the following fields:

      • Pathology
      • Renal
      16.6
      Seconds
  • Question 43 - Gastrocnemius, semimembranosus and semitendinosus together with which other muscle form the boundaries of...

    Correct

    • Gastrocnemius, semimembranosus and semitendinosus together with which other muscle form the boundaries of the popliteal fossa?

      Your Answer: Biceps femoris

      Explanation:

      The popliteal fossa is located at the back of the knee. It is bounded laterally by the biceps femoris above and the plantaris and lateral head of the gastrocnemius below and medially by the semitendinosus and semimembranosus above and by the medial head of the gastrocnemius below.

    • This question is part of the following fields:

      • Anatomy
      • Lower Limb
      3.2
      Seconds
  • Question 44 - Which foramen contains the vertebral artery? ...

    Correct

    • Which foramen contains the vertebral artery?

      Your Answer: Foramen magnum

      Explanation:

      The foramen magnum is found in the most inferior part of the posterior cranial fossa. It is traversed by vital structures including the medulla oblongata. Its contents include the following: medulla oblongata, meninges, spinal root of the accessory nerve, vertebral arteries, anterior and posterior spinal arteries, tectorial membrane and alar ligaments.

    • This question is part of the following fields:

      • Anatomy
      • Head & Neck
      6.6
      Seconds
  • Question 45 - Which of the cranial nerves is responsible for touch sensation on the skin...

    Correct

    • Which of the cranial nerves is responsible for touch sensation on the skin over the maxilla region and the mandible?

      Your Answer: Trigeminal

      Explanation:

      The sensation of the face is provided by the trigeminal nerve which is cranial nerve V. It is also responsible for other motor functions such as biting and chewing. The trigeminal nerve has three branches; the ophthalmic nerve (V1), the maxillary nerve((V2) and the mandibular nerve (V3). These three branches exit the skull through separate foramina, namely; the superior orbital fissure, the foramen rotundum and the foramen ovale respectively. The mnemonic for this is ‘Standing room only’. The sensory fibres of the maxillary nerve are distributed to the lower eyelid and cheek, the nares and upper lip, the upper teeth and gums, the nasal mucosa, the palate and roof of the pharynx, the maxillary, ethmoid and sphenoid sinuses, and parts of the meninges. The sensory fibres of the mandibular nerve are distributed to the lower lip, the lower teeth and gums, the floor of the mouth, the anterior two-thirds of the tongue, the chin and jaw (except the angle of the jaw, which is supplied by C2–C3), parts of the external ear, and parts of the meninges. The mandibular nerve carries touch/ position and pain/temperature sensation from the mouth. The sensory fibres of the ophthalmic nerve are distributed to the scalp and forehead, the upper eyelid, the conjunctiva and cornea of the eye, the nose (including the tip of the nose), the nasal mucosa, the frontal sinuses and parts of the meninges (the dura and blood vessels). The sensory fibres of the maxillary nerve are distributed to the lower eyelid and cheek, the nares and upper lip, the upper teeth and gums, the nasal mucosa, the palate and roof of the pharynx, the maxillary, ethmoid and sphenoid sinuses, and parts of the meninges.

    • This question is part of the following fields:

      • Anatomy
      • Head & Neck
      4.3
      Seconds
  • Question 46 - The following structures DO NOT lie between the layers of the mesosalpinx except...

    Correct

    • The following structures DO NOT lie between the layers of the mesosalpinx except for the?

      Your Answer: Fallopian tube

      Explanation:

      Mesosalpinx is the portion of the broad ligament that stretches from the fallopian tube to the ovary and contains the uterine tubes between it’s layers.

    • This question is part of the following fields:

      • Anatomy
      • Pelvis
      42.7
      Seconds
  • Question 47 - The circle of Willis is one of the cerebrovascular safeguards comprised of the...

    Correct

    • The circle of Willis is one of the cerebrovascular safeguards comprised of the left and the right posterior communicating artery. Which of the following arteries in the brain is connected to the posterior cerebral artery by these posterior communicating arteries?

      Your Answer: Internal carotid artery

      Explanation:

      The Circle of Willis is an anastomosis of cerebral arteries that are located at the base of the brain. The Circle of Willis is one of the important safeguards that ensure back up of blood supply to parts of the brain in case of any cerebrovascular accident. The Circle of Willis is made up of an anterior portion of arteries including; the anterior cerebral arteries. The anterior cerebral arteries are connected to the posterior portion of the circle of Willis by the anterior communicating artery. The posterior portion is made up of the posterior cerebral artery which branch off from the basilar artery. The posterior cerebral artery are connected to the anterior portion of the circle of Willis by the posterior communicating artery. The posterior communicating artery connects the posterior cerebral artery to the internal carotid artery. The circle of Willis receives blood supply from the left and right internal carotid arteries that continues as the middle cerebral artery and posteriorly from the two vertebral arteries that join to form the basilar artery.

    • This question is part of the following fields:

      • Anatomy
      • Head & Neck
      4.6
      Seconds
  • Question 48 - Which of the following statements regarding aqueous humour is correct? ...

    Incorrect

    • Which of the following statements regarding aqueous humour is correct?

      Your Answer: It only fills the anterior chamber of the eye

      Correct Answer: Is the only source of nutrients for the lens of the eye

      Explanation:

      The aqueous humour is a transparent, watery fluid similar to plasma, but containing low protein concentrations. It is secreted from the ciliary epithelium and fills both the anterior and the posterior chambers of the eye. It maintains the intraocular pressure and inflates the globe of the eye. It is this hydrostatic pressure which keeps the eyeball in a roughly spherical shape and keeps the walls of the eyeball taut. It provides nutrition (e.g. amino acids and glucose) for the avascular ocular tissues; posterior cornea, trabecular meshwork, lens, and anterior vitreous. It may serve to transport ascorbate into the anterior segment to act as an antioxidant agent. The presence of immunoglobulins indicate its role in immune response to defend against pathogens.

    • This question is part of the following fields:

      • Anatomy
      • Head & Neck
      11.3
      Seconds
  • Question 49 - A victim of assault in a domestic violence is stabbed in the left...

    Correct

    • A victim of assault in a domestic violence is stabbed in the left chest. The tip of the pen knife entered the pleural space just above the cardiac notch. Luckily the lung was spared as it would only occupy this space during deep inspiration. Which of these structures was pierced by the knife?

      Your Answer: Costomediastinal recess

      Explanation:

      The costomediastinal recess is located immediately next to the cardiac notch. The medial aspect of the superior lobe of the left lung, when fully inflated expands to this place. The lung wouldn’t enter the anterior or the posterior mediastinum which are found between the two pleural cavities.

      The costodiaphragmatic recess is the lowest extent of the pleural cavity where the inferior lobes of the lungs would expand into in deep inhalation.

      The cupola, is the part of the pleural cavity that extends above the first rib into the root of the neck. The superior most part of the superior lobe of the lung might extend into this part.

      Pulmonary ligament: pleural fold that is located below the root of the lung where the visceral pleura and the mediastinal pleura are in continuity.

    • This question is part of the following fields:

      • Anatomy
      • Thorax
      15.9
      Seconds
  • Question 50 - During a car accident, the side mirror shattered and a broken piece of...

    Incorrect

    • During a car accident, the side mirror shattered and a broken piece of glass severed the posterolateral aspect of the driver's neck. A physical examination reveals that the driver is unable to elevate the tip of his shoulder on the side that was injured. Which nerve was injured?

      Your Answer:

      Correct Answer: Accessory

      Explanation:

      The tip of the shoulder is formed by the acromion of the scapula. This part is moved by the trapezius muscle which is innervated by the accessory nerve. Damage to this nerve therefore will prevent the patient from lifting the tip of the shoulder.

    • This question is part of the following fields:

      • Anatomy
      • Head & Neck
      0
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Physiology (8/12) 67%
Respiratory (2/4) 50%
Fluids & Electrolytes (1/1) 100%
Pathology (11/12) 92%
Haematology (2/2) 100%
Anatomy (18/25) 72%
Lower Limb (2/2) 100%
General (4/5) 80%
Pelvis (3/3) 100%
Inflammation & Immunology (1/1) 100%
Abdomen (3/5) 60%
Upper Limb (3/3) 100%
Head & Neck (4/6) 67%
Thorax (3/6) 50%
Pharmacology (1/1) 100%
Neurology (2/2) 100%
Cardiovascular (0/1) 0%
Endocrine (0/1) 0%
Cell Injury & Wound Healing (1/1) 100%
Inflammation & Immunology; Renal (1/1) 100%
Neoplasia (1/1) 100%
Gastroenterology (1/1) 100%
Women's Health (1/1) 100%
Renal (1/1) 100%
Passmed