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  • Question 1 - During the inflammatory phase of wound healing what is the predominant cell type...

    Correct

    • During the inflammatory phase of wound healing what is the predominant cell type found in the wound during days 3-4?

      Your Answer: Macrophages

      Explanation:

      PMNs phagocytise debris and kill bacteria via free radicals (AKA respiratory burst). They also break down damaged tissue. PMNs typically undergo apoptosis after 48 hours. They are then engulfed and degraded by macrophages. Macrophages therefore become the predominant cell type in the wound on days 3-4.

    • This question is part of the following fields:

      • Physiology
      17.8
      Seconds
  • Question 2 - The maternal blood volume in normal pregnancy: ...

    Incorrect

    • The maternal blood volume in normal pregnancy:

      Your Answer: Increases 10%

      Correct Answer: Increases up to 40%

      Explanation:

      Changes in the cardiovascular system in pregnancy are profound and begin early in pregnancy, such that by eight weeks’ gestation, the cardiac output has already increased by 20%. The primary event is probably peripheral vasodilatation. This is mediated by endothelium-dependent factors, including nitric oxide synthesis, upregulated by oestradiol and possibly vasodilatory prostaglandins (PGI2). Peripheral vasodilation leads to a 25–30% fall in systemic vascular resistance, and to compensate for this, cardiac output increases by around 40% during pregnancy. 

    • This question is part of the following fields:

      • Physiology
      7
      Seconds
  • Question 3 - Regarding electronic fetal monitoring, which one of the following statements is true? ...

    Incorrect

    • Regarding electronic fetal monitoring, which one of the following statements is true?

      Your Answer: Has high specificity & sensitivity

      Correct Answer: Has low specificity but high sensitivity

      Explanation:

      There are different ways of monitoring fetal heart rate during pregnancy. It can be done by just auscultation or by electronic fetal heart rate monitoring which is done with the help of an ultrasound machine and has a low specificity but high sensitivity.

    • This question is part of the following fields:

      • Physiology
      11.3
      Seconds
  • Question 4 - What percentage of haemoglobin is HbF by 6 months of age? ...

    Incorrect

    • What percentage of haemoglobin is HbF by 6 months of age?

      Your Answer: 50%

      Correct Answer:

      Explanation:

      HB gower 1 is the predominant embryonic haemoglobin when the foetus is 6 week old and is replaced by adult haemoglobin by the age of 5 months post natally. Only 2% of the haemoglobin is HbF.

      Embryonic Haemoglobin:
      Haemoglobin Gower 1 (HbE Gower-1)
      Haemoglobin Gower 2 (HbE Gower-2)
      Haemoglobin Portland I (HbE Portland-1)
      Haemoglobin Portland II (HbE Portland-2)

      Fetal Haemoglobin (haemoglobin F, HbF)

    • This question is part of the following fields:

      • Physiology
      51.5
      Seconds
  • Question 5 - A 29-year-old gravida 6, para 5 woman at 36 weeks of gestation arrives...

    Incorrect

    • A 29-year-old gravida 6, para 5 woman at 36 weeks of gestation arrives in the ED via ambulance and precipitously delivers a male child. The child coughs and has a strong cry. He is very active. Acrocyanosis is noted. Heart rate is 98 bpm and breathing is strong. What is this child’s Apgar score?

      Your Answer: 8

      Correct Answer: 5

      Explanation:

      The Apgar test scores appearance, pulse, grimace, activity, and respiration and is generally done at 1 and 5 minutes after birth but may be repeated if the child continues to score low (Table). This child’s score is as follows: Appearance, 1; Pulse, 1; Grimace, 2; Activity, 2; Respiration, 2 (APGAR score = 8). A score of 3 or less is generally regarded as critically low, 4 to 6 is fairly low, and 7 to 10 is generally normal. Contrary to common belief, the Apgar score is not used to decide if a neonate requires resuscitation. Decisions about resuscitation are based on emergency assessment of airway, breathing, and circulation.5,6

    • This question is part of the following fields:

      • Physiology
      51.1
      Seconds
  • Question 6 - Which of the following increases during pregnancy? ...

    Incorrect

    • Which of the following increases during pregnancy?

      Your Answer: Expiratory Reserve Volume

      Correct Answer: Tidal Volume

      Explanation:

      Ventilation begins to increase significantly at around 8 weeks of gestation, most likely in response to progesterone-related sensitization of the respiratory centre to carbon dioxide and the increased metabolic rate. Significant alterations occur in the mechanical aspects of ventilation during pregnancy. Minute ventilation (or the amount of air moved in and out of the lungs in 1 minute) is the product of tidal volume and respiratory rate and increases by approximately 30–50 per cent with pregnancy. The increase is primarily a result of tidal volume, which increases by 40 per cent (from 500 to 700 mL), because the respiratory rate remains unchanged. The increase in minute ventilation is perceived by the pregnant woman as shortness of breath, which affects 60–70 per cent of women. This physiological dyspnoea is usually mild and affects 50 per cent of women before 20 weeks gestation, but resolves immediately postpartum.

    • This question is part of the following fields:

      • Physiology
      14.4
      Seconds
  • Question 7 - Immediate delivery of the foetus is recommended at which fetal scalp pH? ...

    Correct

    • Immediate delivery of the foetus is recommended at which fetal scalp pH?

      Your Answer: 7.18

      Explanation:

      A pH value below than 7.18 indicates acidosis which can result in hypoxic brain injury. In order to prevent brain injury, immediate delivery of the foetus should be planned. The normal range for a term baby is pH: 7.18 – 7.38, preterm pH: 7.14 – 7.4.

    • This question is part of the following fields:

      • Physiology
      30
      Seconds
  • Question 8 - Which one of the following factors will most likely increase the chances of...

    Incorrect

    • Which one of the following factors will most likely increase the chances of ovulation in female?

      Your Answer: Thermogenic shift in basal body temperature

      Correct Answer: LH surge

      Explanation:

      Different changes can occur during the menstrual cycle including an increased body temperature at the time of ovulation, thinning of the cervical mucus and few other changes, but it is the LH surge which is the most important factor necessary for ovulation.
      Mittelschmerz is characterised by recurrent midcycle pain which occurs around the time of ovulation.

    • This question is part of the following fields:

      • Physiology
      9.5
      Seconds
  • Question 9 - In the earliest phase of wound healing platelets are held together by what?...

    Incorrect

    • In the earliest phase of wound healing platelets are held together by what?

      Your Answer: Fibroblasts

      Correct Answer: Fibrin

      Explanation:

      The 1st stage of wound healing is haemostasis. Even in incised wounds a small haematoma forms. Here the clotting cascade is activated by tissue factor and endothelial cells resulting in activation of platelets. This results in platelet aggregation and the laying down of a fibrin mesh that is cross linked and holds the platelets in place.
      Wound healing is typically divided into phases:
      1. Haemostasis Phase
      2. Inflammatory phase
      3. Proliferation phase
      4. Remodelling phase

    • This question is part of the following fields:

      • Physiology
      10.1
      Seconds
  • Question 10 - What percentage of patients with breast cancer have hypercalcaemia ...

    Incorrect

    • What percentage of patients with breast cancer have hypercalcaemia

      Your Answer: 2-3%

      Correct Answer: 20%

      Explanation:

      20% of the patients with breast cancer will have hypercalcemia.

    • This question is part of the following fields:

      • Physiology
      19.6
      Seconds
  • Question 11 - After birth, all of the following vessels constrict, EXCEPT the: ...

    Correct

    • After birth, all of the following vessels constrict, EXCEPT the:

      Your Answer: Hepatic portal vein

      Explanation:

      Immediately after birth the liver is deprived of the large flow of blood supplied during foetal development via the umbilical vein and portal sinus. Simultaneously the blood pressure in the portal sinus, previously as high as in the umbilical vein, falls.

    • This question is part of the following fields:

      • Physiology
      6.8
      Seconds
  • Question 12 - During normal pregnancy, a weight gain is anticipated. The average weight gain is...

    Incorrect

    • During normal pregnancy, a weight gain is anticipated. The average weight gain is approximately:

      Your Answer: 30-40 kg

      Correct Answer: 10-15 kg

      Explanation:

      Institute of Medicine Weight Gain Recommendations for Pregnancy: Recommends a gestational weight gain of 16.8–24.5 kg (37–54 lb) for women of normal weight, 14.1–22.7 kg (31–50 lb) for overweight women, and 11.3–19.1 kg (25–42 lb) for obese women.

    • This question is part of the following fields:

      • Physiology
      18.3
      Seconds
  • Question 13 - What is the typical volume increase of a non-pregnant uterus to term uterus?...

    Incorrect

    • What is the typical volume increase of a non-pregnant uterus to term uterus?

      Your Answer: 10ml to 1000ml

      Correct Answer: 10ml to 5000ml

      Explanation:

      Uterine blood flow increases 40-fold to approximately 700 mL/min at term. The uterus is 50–60 g with a volume of approximately 10ml prior to pregnancy and 1000 – 1200 g with a volume of 5000ml by term.

    • This question is part of the following fields:

      • Physiology
      13.9
      Seconds
  • Question 14 - Spinnbarkheit is a term which means: ...

    Incorrect

    • Spinnbarkheit is a term which means:

      Your Answer: Crystallization of the cervical mucous

      Correct Answer: Threading of the cervical mucous

      Explanation:

      Spinnability (or Spinnbarkeit), which measures the capacity of fluids to be drawn into threads, represents an indirect measurement of the adhesive and elastic properties of mucus.

    • This question is part of the following fields:

      • Physiology
      10.8
      Seconds
  • Question 15 - Which one of the following statements regarding fetal blood pH is correct? ...

    Correct

    • Which one of the following statements regarding fetal blood pH is correct?

      Your Answer: Can be measured during labour

      Explanation:

      A sample for fetal blood pH can be taken during the labour. The mother should be lying in a left lateral position.

    • This question is part of the following fields:

      • Physiology
      11.2
      Seconds
  • Question 16 - Which of the following lung function values is unchanged in pregnancy? ...

    Incorrect

    • Which of the following lung function values is unchanged in pregnancy?

      Your Answer: ERV

      Correct Answer: FEV1

      Explanation:

      FEV1 and FVC are unchanged. FEV1/FVC ratio remains the same in pregnancy

    • This question is part of the following fields:

      • Physiology
      12.7
      Seconds
  • Question 17 - Which of the following would normally be expected to increase during pregnancy: ...

    Incorrect

    • Which of the following would normally be expected to increase during pregnancy:

      Your Answer: Hair growth

      Correct Answer: Thyroxin-binding globulin

      Explanation:

      Thyroid function in pregnancy is altered in two ways; the circulating levels of the thyroid binding proteins are increased, resulting in an increase in the total circulating levels of thyroid hormones (but a slight fall in the free component).

    • This question is part of the following fields:

      • Physiology
      25.4
      Seconds
  • Question 18 - In normal physiological changes in pregnancy, all of the following are increased, EXCEPT:...

    Correct

    • In normal physiological changes in pregnancy, all of the following are increased, EXCEPT:

      Your Answer: Peripheral resistance

      Explanation:

      The heart adapts to the increased cardiac demand that occurs during pregnancy in many ways:
      Cardiac output increases throughout early pregnancy, and peaks in the third trimester, usually to 30-50% above baseline.
      Oestrogen mediates this rise in cardiac output by increasing the pre-load and stroke volume, mainly via a higher overall blood volume (which increases by 40–50%).
      The heart rate increases, but generally not above 100 beats/ minute.
      Total systematic vascular resistance decreases by 20% secondary to the vasodilatory effect of progesterone. Overall, the systolic and diastolic blood pressure drops 10–15 mm Hg in the first trimester and then returns to the baseline in the second half of pregnancy.
      All of these cardiovascular adaptations can lead to common complaints, such as palpitations, decreased exercise tolerance, and dizziness

      A pregnant woman may experience an increase in the size of the kidneys and ureter due to the increased blood volume and vasculature.
      Later in pregnancy, the woman might develop physiological hydronephrosis and hydroureteronephrosis, which are normal.
      There is an increase in glomerular filtration rate associated with an increase in creatinine clearance, protein, albumin excretion, and urinary glucose excretion.
      There is also an increase in sodium retention from the renal tube so oedema and water retention is a common sign in pregnant women

    • This question is part of the following fields:

      • Physiology
      18.4
      Seconds
  • Question 19 - During wound healing the clotting cascade is activated. Which of the following activates...

    Incorrect

    • During wound healing the clotting cascade is activated. Which of the following activates the extrinsic pathway?

      Your Answer: Fibrin

      Correct Answer: Tissue Factor

      Explanation:

      The extrinsic pathway is activated by the tissue factor, which converts factor VII to VIIa which later on converts factors X and II to their activated form finally leading to the conversion of fibrinogen to fibrin fibres.

    • This question is part of the following fields:

      • Physiology
      20
      Seconds
  • Question 20 - If a sample of cervical mucus is taken on the 12th day of...

    Incorrect

    • If a sample of cervical mucus is taken on the 12th day of the menstrual cycle and examined under the microscope, what kind of findings would be observed?

      Your Answer: Clear fields, devoid of bacteria Cell

      Correct Answer: A fern pattern characteristic of oestrogen

      Explanation:

      Fern test looks for a specific fern like pattern of cervical mucus when observed under light microscope after the sample is dried. It occurs due to the presence of sodium chloride under oestrogen influence whereas progesterone opposes it.

    • This question is part of the following fields:

      • Physiology
      45.7
      Seconds
  • Question 21 - Physiological changes in the reproductive system include: ...

    Incorrect

    • Physiological changes in the reproductive system include:

      Your Answer: There is no change in the cervix

      Correct Answer: The uterus 1st enlarges by hyperplasia then by hypertrophy

      Explanation:

      Although uterine growth during the first few weeks of pregnancy is accomplished by increased numbers of smooth muscle cells (i.e. hyperplasia) and a smaller contribution from increased cell size (i.e. hypertrophy), the predominant growth of the uterus during pregnancy is by way of stretch‐induced myometrial hypertrophy. This ongoing process of stretch‐induced tissue remodelling and smooth muscle hypertrophy is accompanied by the lack of uterine contractions during most of gestation to accommodate the developing foetus (phase 0 of parturition). Phase 1 of parturition represents myometrial activation. The final stages of pregnancy are characterized by increases in spontaneous low‐amplitude contractions that gradually increase in frequency, rhythmicity and strength, normally culminating in labour and delivery of the foetus at term (phase 2 of parturition).

    • This question is part of the following fields:

      • Physiology
      35.7
      Seconds
  • Question 22 - Which one of the following statements regarding oestrogen is correct? ...

    Incorrect

    • Which one of the following statements regarding oestrogen is correct?

      Your Answer: Can not be detected in the blood of postmenopausal women

      Correct Answer: It is produced in the corpus luteum

      Explanation:

      Oestrogen is secreted by the corpus luteum and is responsible for the proliferation of the endometrium to prepare it for the implantation of the zygote.

    • This question is part of the following fields:

      • Physiology
      6.6
      Seconds
  • Question 23 - Maternal mortality rate is lowest in which age group? ...

    Incorrect

    • Maternal mortality rate is lowest in which age group?

      Your Answer: 30 - 40

      Correct Answer: 20 - 30

      Explanation:

      The maternal mortality rate starts low and raises steeply after the age of 30 years. The lowest mortality rate recorded among women is between 19-30 years of age group.

    • This question is part of the following fields:

      • Physiology
      10.4
      Seconds
  • Question 24 - The second stage of labour involves: ...

    Incorrect

    • The second stage of labour involves:

      Your Answer: Separation of the placenta

      Correct Answer: Expulsion of the foetus

      Explanation:

      First stage: The latent phase is generally defined as beginning at the point at which the woman perceives regular uterine contractions. A definition of active labour is having contractions more frequent than every 5 minutes, in addition to either a cervical dilation of 3 cm or more or a cervical effacement of 80% or more.

      Second stage: fetal expulsion begins when the cervix is fully dilated, and ends when the baby is born.

      Third stage: placenta delivery – The period from just after the foetus is expelled until just after the placenta is expelled is called the third stage of labour or the involution stage.

    • This question is part of the following fields:

      • Physiology
      6.3
      Seconds
  • Question 25 - What is the primary form of haemoglobin in a 6 week old foetus?...

    Incorrect

    • What is the primary form of haemoglobin in a 6 week old foetus?

      Your Answer: Hb Portland 1

      Correct Answer: Hb Gower 1

      Explanation:

      HB gower 1 is the predominant embryonic haemoglobin when the foetus is 6 weeks old and is replaced by adult haemoglobin by the age of 5 months post natally.

    • This question is part of the following fields:

      • Physiology
      15
      Seconds
  • Question 26 - Skin changes during pregnancy should include: ...

    Incorrect

    • Skin changes during pregnancy should include:

      Your Answer: Palmar erythema

      Correct Answer: All of the options given

      Explanation:

      Skin signs during pregnancy may include: dark spots on the breasts, nipples and inner thighs, melasma (chloasma), linea nigra, stretch marks, acne, spider telangiectasis and varicose veins.

    • This question is part of the following fields:

      • Physiology
      10.7
      Seconds
  • Question 27 - When does ovulation occur? ...

    Incorrect

    • When does ovulation occur?

      Your Answer: 6-8 hours after LH surge

      Correct Answer: 36 hours after LH surge

      Explanation:

      Ovulation occurs in the mid stage of the menstrual cycle, usually 36 hours after the LH surge. It is this LH surge which is necessary for the ovulation to occur.

    • This question is part of the following fields:

      • Physiology
      28.2
      Seconds
  • Question 28 - Changes in the urinary tract system in pregnancy include: ...

    Correct

    • Changes in the urinary tract system in pregnancy include:

      Your Answer: Increase in the glomerular filtration rate (GFR)

      Explanation:

      Pregnancy involves remarkable orchestration of physiologic changes. The kidneys are central players in the evolving hormonal milieu of pregnancy, responding and contributing to the changes in the environment for the pregnant woman and foetus. The functional impact of pregnancy on kidney physiology is widespread, involving practically all aspects of kidney function. The glomerular filtration rate increases 50% with subsequent decrease in serum creatinine, urea, and uric acid values. 

    • This question is part of the following fields:

      • Physiology
      11.5
      Seconds
  • Question 29 - Regarding heart rate in pregnancy which of the following statements is true? ...

    Incorrect

    • Regarding heart rate in pregnancy which of the following statements is true?

      Your Answer: Heart rate remains constant

      Correct Answer: Heart rate increases by 15 beats per minute

      Explanation:

      The following cardiovascular changes occur during pregnancy:
      – Blood volume slowly increases by 40-50%
      – Heart rate rises by 15 beats/min above baseline
      – Stroke volume increases by 25-30%
      – Cardiac output increases by approximately 30-50%
      – Systemic vascular resistance (SVR) decreases by 20-30%
      – Diastolic blood pressure consequently decreases between 12 and 26 weeks but increases again to pre-pregnancy levels by 36 weeks.
      As most of the changes occur in the first 12 weeks of gestation cardiac problems are likely to present in early pregnancy

    • This question is part of the following fields:

      • Physiology
      25.4
      Seconds
  • Question 30 - All of the following factors are associated with umbilical cord prolapse, except? ...

    Incorrect

    • All of the following factors are associated with umbilical cord prolapse, except?

      Your Answer: Footing breech presentation

      Correct Answer: Anencephaly

      Explanation:

      Anencephaly means the missing of a particular portion of the scalp and brain tissue. The other factors listed are associated with umbilical cord prolapse like multiparity, twin birth, polyhydramnios, premature delivery, long umbilical cord or breech presentation.

    • This question is part of the following fields:

      • Physiology
      12.6
      Seconds
  • Question 31 - Excessive increased level of β-HCG is expected in: ...

    Incorrect

    • Excessive increased level of β-HCG is expected in:

      Your Answer: Ectopic pregnancy

      Correct Answer: Twin pregnancy

      Explanation:

      Human chorionic gonadotropin levels dynamically increase during early gestation and the levels are significantly greater in viable pregnancies than in ectopic gestation, biochemical pregnancy, or spontaneous abortions. Similarly, the hCG concentrations are significantly higher in multiple pregnancy as compared with singleton.

    • This question is part of the following fields:

      • Physiology
      10.8
      Seconds
  • Question 32 - Regarding cardiac output in pregnancy which of the following statements is TRUE? ...

    Incorrect

    • Regarding cardiac output in pregnancy which of the following statements is TRUE?

      Your Answer: None of the above

      Correct Answer: Cardiac output increases by approximately 40-50% during pregnancy

      Explanation:

      In a non pregnant adult female the cardiac output is 4.5L/min, by the 20 week of pregnancy the cardiac output increases by 40% to 6.3L/min. During early stages of labour it increases further still by 17% to 7.3L/min.

    • This question is part of the following fields:

      • Physiology
      28.8
      Seconds
  • Question 33 - Regarding cardiac examination during pregnancy which of the following findings should be considered...

    Correct

    • Regarding cardiac examination during pregnancy which of the following findings should be considered pathological

      Your Answer: Diastolic murmur

      Explanation:

      Diastolic murmurs should be considered pathological until proven otherwise. The following are common and typically benign findings in pregnancy: A third heart sound after mid-pregnancy. Systolic flow murmurs are common. Left axis deviation on ECG is common, Sagging ST segments and inversion or flattening of the T wave in lead III may also occur

    • This question is part of the following fields:

      • Physiology
      23.7
      Seconds
  • Question 34 - The test used to diagnose ovulation on day 21 in a 28 days...

    Incorrect

    • The test used to diagnose ovulation on day 21 in a 28 days menstrual cycle is:

      Your Answer: Oestrogen

      Correct Answer: Progesterone

      Explanation:

      After ovulation, the dominant follicle turns into a corpus luteum and begins to secrete progesterone. To confirm ovulation, serum progesterone or its metabolite in urine, can be measured. A single serum progesterone level >3 ng/ml in mid‐luteal phase has been used to retrospectively detect ovulation.

    • This question is part of the following fields:

      • Physiology
      24.2
      Seconds
  • Question 35 - Ovulation may be indicated by all the following, EXCEPT: ...

    Incorrect

    • Ovulation may be indicated by all the following, EXCEPT:

      Your Answer: Changing of cervical mucous to thick and scanty

      Correct Answer: Mid-cycle elevation in prolactin

      Explanation:

      An elevation in serum PRL is associated with a variety of reproductive disorders, including amenorrhea, oligomenorrhea, anovulation and/or luteal phase defects with subsequent infertility.

    • This question is part of the following fields:

      • Physiology
      15.8
      Seconds
  • Question 36 - Which of the following causes of polyhydramnios is more common? ...

    Incorrect

    • Which of the following causes of polyhydramnios is more common?

      Your Answer: Twin pregnancy

      Correct Answer: Idiopathic

      Explanation:

      Maternal disorders, such as diabetes, in-utero infections, drug usage, placental abnormalities and fetal conditions as congenital and chromosomal abnormalities, Rh iso-immunization, and multiple gestations, are generally associated with polyhydramnios. Congenital abnormalities such as duodenal, oesophageal, or intestinal atresia of the foetus are the most common malformations that typically cause gastro-intestinal obstruction and interfere with fetal swallowing and/or absorption resulting with polyhydramnios. However, in about 70% of cases, none of the aforementioned aetiologies are causes of polyhydramnios, and it is referred to as idiopathic or isolated.

    • This question is part of the following fields:

      • Physiology
      27.7
      Seconds
  • Question 37 - Which of the following is probably responsible for physiologic hyperventilation during pregnancy? ...

    Incorrect

    • Which of the following is probably responsible for physiologic hyperventilation during pregnancy?

      Your Answer: Large fluctuations in plasma bicarbonate

      Correct Answer: Increased progesterone production

      Explanation:

      Progesterone gradually increases during the course of pregnancy, from 25 ng⋅mL−1 at 6 weeks’ to 150 ng⋅mL−1 at 37 weeks’ gestation. Progesterone acts as trigger of the primary respiratory centre by increasing the sensitivity of the respiratory centre to carbon dioxide, as indicated by the steeper slope of the ventilation curve in response to alveolar carbon dioxide changes. Progesterone alters the smooth muscle tone of the airways resulting in a bronchodilator effect. It also mediates hyperaemia and oedema of mucosal surfaces, causing nasal congestion.

    • This question is part of the following fields:

      • Physiology
      10.2
      Seconds
  • Question 38 - At term, what is the rate of uterine blood flow per minute? ...

    Incorrect

    • At term, what is the rate of uterine blood flow per minute?

      Your Answer: 100 to 150 ml/min

      Correct Answer: 500 to 750 ml/min

      Explanation:

      The average volume of uterine blood flow at term is 500-750 ml/min.

    • This question is part of the following fields:

      • Physiology
      7.5
      Seconds
  • Question 39 - In pregnancy, the following lung function value remains unchanged: ...

    Incorrect

    • In pregnancy, the following lung function value remains unchanged:

      Your Answer: ERV

      Correct Answer: FEV1

      Explanation:

      The biochemical and mechanical effects of progesterone and the enlarging uterus are responsible for some changes in lung function during pregnancy.

      Progesterone increases the sensitivity of the respiratory centre to arterial carbon dioxide while also causing hyperaemia in the airway leading to nasal obstruction. As a result, minute ventilation and tidal volume increase by 50% to allow greater arterial oxygen saturation.

      The enlarging uterus displaces the diaphragm upwards, and also limits the movement of the thoracic cage, thereby decreasing the functional residual capacity (FRC) and the expiratory reserve volume (ERV) by 20%.

      Functional Expiratory Volume in 1 second (FEV1) and Forced Vital Capacity (FVC) remain unchanged in pregnancy.

    • This question is part of the following fields:

      • Physiology
      43.1
      Seconds
  • Question 40 - All of the following statements regarding human chorionic gonadotrophin are true except:: ...

    Incorrect

    • All of the following statements regarding human chorionic gonadotrophin are true except::

      Your Answer: Forms the main tumour marker for trophoblastic neoplastic diseases

      Correct Answer: It's level doubles every 48 hours in ectopic pregnancy

      Explanation:

      In normal pregnancy the levels of hCG doubles after every 48-72 hours but in case of ectopic pregnancy the levels of hCG are lower than the normal. It is produced by the placenta and its main role is nourishment of the egg after implantation. Its levels reached a peak at 8-10 weeks of pregnancy and after that the levels decreases for the remainder of pregnancy. In hydatiform mole and trophoblastic diseases its the main hormone for diagnosis of the disease because the levels are highly elevated.

    • This question is part of the following fields:

      • Physiology
      319.9
      Seconds
  • Question 41 - If a hyalinised mass is formed from an involuted corpus leuteum, it is...

    Incorrect

    • If a hyalinised mass is formed from an involuted corpus leuteum, it is known as:

      Your Answer: Corpus atrectica

      Correct Answer: Corpus albicans

      Explanation:

      Corpus albicans is the regressed form of the corpus leuteum. It is formed when the corpus leuteum is engulfed by macrophages and a scar or fibrous tissue is formed, called the corpus albicans.

    • This question is part of the following fields:

      • Physiology
      305.9
      Seconds
  • Question 42 - A 25 year old primigravida with a regular cycle had her last menstrual...

    Incorrect

    • A 25 year old primigravida with a regular cycle had her last menstrual period on June 30th. Therefore the expected date of delivery (EDD) is approximately when the following year:

      Your Answer: 28-Mar

      Correct Answer: 7-Apr

      Explanation:

      Expected date of delivery (EDD) is a calculated from the first day of the woman’s last menstrual period. If her periods are regular i.e., 28-day menstrual cycle, Naegele’s rule may be used. Naegele’s rule involves a simple calculation: add seven days to the first day of your LMP and then subtract three months. e.g. 30 June + 7 days = 7 July, minus 3 months = 7 April.

    • This question is part of the following fields:

      • Physiology
      32.1
      Seconds
  • Question 43 - Lowered haemoglobin during normal pregnancy is a physiological finding which is mainly due...

    Incorrect

    • Lowered haemoglobin during normal pregnancy is a physiological finding which is mainly due to:

      Your Answer: Decreased reticulocytosis

      Correct Answer: Increased plasma volume

      Explanation:

      During pregnancy, anaemia increases more than fourfold from the first to third trimester. It is a well established fact that there is a physiological drop in haemoglobin (Hb) in the mid trimester. This physiological drop is attributed to increase of plasma volume and hence decrease of blood viscosity lead to better circulation in placenta.

    • This question is part of the following fields:

      • Physiology
      88.4
      Seconds
  • Question 44 - In the foetus, the most well oxygenated blood flows into which part of...

    Incorrect

    • In the foetus, the most well oxygenated blood flows into which part of the heart:

      Your Answer: Ductus arteriosus

      Correct Answer: Right atrium

      Explanation:

      The placenta accepts the blue, unoxygenated blood from the foetus through blood vessels that leave the foetus through the umbilical cord (umbilical arteries, there are two of them). When blood goes through the placenta it picks up oxygen and becomes red. The red blood then returns to the foetus via the third vessel in the umbilical cord, the umbilical vein. The red blood that enters the foetus passes through the fetal liver and enters the right side of the heart.

    • This question is part of the following fields:

      • Physiology
      87.6
      Seconds
  • Question 45 - Fetal blood is returned to the umbilical arteries & the placenta via the:...

    Incorrect

    • Fetal blood is returned to the umbilical arteries & the placenta via the:

      Your Answer: Foramen ovale

      Correct Answer: Hypogastric arteries

      Explanation:

      In the foetus, the hypogastric artery ascends along the side of the bladder, and runs upward on the back of the anterior wall of the abdomen to the umbilicus, converging toward its fellow of the opposite side. Having passed through the umbilical opening, the two arteries, now termed umbilical, enter the umbilical cord, where they are coiled around the umbilical vein, and ultimately ramify in the placenta.

    • This question is part of the following fields:

      • Physiology
      76.3
      Seconds
  • Question 46 - Which of the following statements is true regarding heart rate in pregnancy? ...

    Correct

    • Which of the following statements is true regarding heart rate in pregnancy?

      Your Answer: Heart rate increases by 15 beats per minute

      Explanation:

      During the first 12 weeks of pregnancy, cardiac output increases by about 30-50%. To maintain this increase, systemic vascular resistance decreases by 20-30%, while stroke volume and the heart rate increase by 25-30% and 15 beats per minute respectively.

    • This question is part of the following fields:

      • Physiology
      11.5
      Seconds
  • Question 47 - What is the typical weight of a term uterus? ...

    Incorrect

    • What is the typical weight of a term uterus?

      Your Answer: 800g

      Correct Answer: 1200g

      Explanation:

      Uterine blood flow increases 40-fold to approximately 700 mL/min at term, with 80 per cent of the blood distributed to the intervillous spaces of the placentae, and 20 per cent to the uterine myometrium. Weight of the uterus increases from 50–60 g prior to pregnancy to 1000 g by term.

    • This question is part of the following fields:

      • Physiology
      33.4
      Seconds
  • Question 48 - Besides infertility, the most common symptoms of a luteal phase defect is: ...

    Incorrect

    • Besides infertility, the most common symptoms of a luteal phase defect is:

      Your Answer: Breast tenderness

      Correct Answer: Early abortion

      Explanation:

      Luteal phase defect is an ovulatory disorder of considerable clinical importance that is implicated in infertility and recurrent spontaneous abortion. 

    • This question is part of the following fields:

      • Physiology
      20.7
      Seconds
  • Question 49 - CTG showing early decelerations is : ...

    Incorrect

    • CTG showing early decelerations is :

      Your Answer: A decrease in the fetal heart beat that peaks after the peak of uterine contraction

      Correct Answer: From increased vagal tone secondary to head compression

      Explanation:

      Early decelerations: a result of increased vagal tone due to compression of the fetal head during contractions. Monitoring usually shows a symmetrical, gradual decrease and return to baseline of FHR, which is associated with a uterine contraction.

    • This question is part of the following fields:

      • Physiology
      142.4
      Seconds
  • Question 50 - Which one of the following features best describes the role of prostaglandins? ...

    Incorrect

    • Which one of the following features best describes the role of prostaglandins?

      Your Answer:

      Correct Answer: Are involved in the onset of labour

      Explanation:

      Prostaglandins are involved in the uterine contraction and cervical dilatation during labour. Higher prostaglandin concentrations can also lead to severe menstrual cramps.

    • This question is part of the following fields:

      • Physiology
      0
      Seconds

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