00
Correct
00
Incorrect
00 : 00 : 00
Session Time
00 : 00
Average Question Time ( Mins)
Retry this test Dashboard

  • Question 1 - Which of the following will require Anti-D administration post partum? ...

    Correct

    • Which of the following will require Anti-D administration post partum?

      Your Answer: Rhesus negative mother, non-sensitised, fetal cord blood Rh positive

      Explanation:

      Rhesus positive mothers should not get anti-D. They have Rhesus antigens and the anti-D would result in maternal blood being bound and removed from her circulation. The danger is to children born to mothers who are rhesus negative. As the mother may develop antibodies against Rhesus positive fetal blood. Therefore if the baby is Rhesus negative then there is no risk of alloimmunisation (sensitisation)

    • This question is part of the following fields:

      • Immunology
      36.2
      Seconds

  • Question 2 - You see a patient in antenatal clinic who is concerned that she has...

    Correct

    • You see a patient in antenatal clinic who is concerned that she has never had chicken pox and may catch it during pregnancy. You check her Varicella status and she is non-immune. She asks you about vaccination. What type of vaccine is the varicella vaccine?

      Your Answer: Attenuated

      Explanation:

      Varicella is a live vaccine. The recent RCOG green top guidelines suggest vaccine can be considered postpartum or pre pregnancy but NOT whilst pregnant. In the non-immune pregnant woman they should be advised to avoid contact with people with chickenpox or shingles and to contact a healthcare professional promptly if exposed. If they have a significant exposure VZIG should be offered as soon as possible.

    • This question is part of the following fields:

      • Immunology
      214.2
      Seconds

  • Question 3 - You have just clerked in a patient on the labour ward who has...

    Correct

    • You have just clerked in a patient on the labour ward who has SLE. What type of hypersensitivity reaction is SLE an example of?

      Your Answer: Type III

      Explanation:

      SLE is a type III hypersensitivity reaction

    • This question is part of the following fields:

      • Immunology
      14.5
      Seconds

  • Question 4 - Which Immunoglobulin (or antibody) is secreted in large amounts in breast milk? ...

    Correct

    • Which Immunoglobulin (or antibody) is secreted in large amounts in breast milk?

      Your Answer: IgA

      Explanation:

      When considering immunoglobulins in neonates. There are only a few key points you are likely to be tested on. 1. IgA is resistant to stomach acid and found in large amounts in breast milk. 2. IgG is the only Ig that can cross the placenta so is key for passive neonatal immunity 3. When the neonate starts synthesising its own Ig it is IgM that is produced first.

    • This question is part of the following fields:

      • Immunology
      8.3
      Seconds

  • Question 5 - Fetal immunoglobulin production begins at what gestation? ...

    Incorrect

    • Fetal immunoglobulin production begins at what gestation?

      Your Answer: Week 32

      Correct Answer: Week 10

      Explanation:

      Fetal production of immunoglobulin begins early on, at about 10 weeks gestation with the production of IgM antibodies. Maternal IgG, which is a key component of fetal immunity, is passed on to the foetus through the placenta from 12 weeks of gestation. Secretory IgA is not produced until after birth.

    • This question is part of the following fields:

      • Immunology
      17.1
      Seconds

  • Question 6 - Which immunoglobulin provides passive immunity to the neonate? ...

    Correct

    • Which immunoglobulin provides passive immunity to the neonate?

      Your Answer: IgG

      Explanation:

      Passive immunity to the neonate is provided by immunoglobulin G (IgG) since it can be transferred through the placenta from mother to the foetus.
      IgA is transferred from mothers to offspring through breast milk.
      IgM molecular structure is too big to be filtered through the placental vasculature to the foetus. IgM is the first Ig to be synthesised by the neonate

    • This question is part of the following fields:

      • Immunology
      3.3
      Seconds

  • Question 7 - Which of the following is a tumour marker for ovarian cancer? ...

    Correct

    • Which of the following is a tumour marker for ovarian cancer?

      Your Answer: Ca 125

      Explanation:

      CA-125 is the tumour marker specific for ovarian carcinoma.

    • This question is part of the following fields:

      • Immunology
      5.4
      Seconds

  • Question 8 - Which of the following increases in pregnancy? ...

    Incorrect

    • Which of the following increases in pregnancy?

      Your Answer: IFN-y

      Correct Answer: Th2

      Explanation:

      T-Helper cells type 2 increase during pregnancy. They secret cytokines IL-4,5,9,10 and 13.

    • This question is part of the following fields:

      • Immunology
      17
      Seconds

  • Question 9 - Rhesus D immunoglobin treatment utilises what class of antibody? ...

    Incorrect

    • Rhesus D immunoglobin treatment utilises what class of antibody?

      Your Answer: IgD

      Correct Answer: IgG

      Explanation:

      It utilizes the IgG class of the antibody.

    • This question is part of the following fields:

      • Immunology
      37.7
      Seconds

  • Question 10 - At what stage of gestation does fetal immunoglobulin M production begin? ...

    Correct

    • At what stage of gestation does fetal immunoglobulin M production begin?

      Your Answer: Week 10

      Explanation:

      Maternofetal IgG transfer starts around week 12. Fetal production IgM starts around week 10 to 11.

    • This question is part of the following fields:

      • Immunology
      6.9
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Immunology (7/10) 70%
Passmed
Retry this test Dashboard