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  • Question 1 - The cavernous sinus is? ...

    Correct

    • The cavernous sinus is?

      Your Answer: Lateral to the body of the sphenoid

      Explanation:

      It is a venous sinus which creates a cavity called the lateral sellar compartment bordered by the temporal bone and the sphenoid bone. There are 2 on either side. It is about 1cm wide and extends from the posterior aspect of the orbit to the petrous part of the temporal bone. They sit on either side or lateral to the sphenoid bone.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      16.9
      Seconds

  • Question 2 - The main reason for the prolonged effect of the withdrawal reflex is: ...

    Incorrect

    • The main reason for the prolonged effect of the withdrawal reflex is:

      Your Answer: Fast afferent conduction

      Correct Answer: Multiple connections between afferent and efferent neurons

      Explanation:

      The withdrawal reflex is a spinal reflex that protects the body from harmful stimuli. Spinal reflexes are mostly monosynaptic and are mediated by a simple reflex arc. Withdrawal reflex is mediated by a polysynaptic reflex resulting in stimulation of many motor neurons in order to establish a quick and prolonged response.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      3.9
      Seconds

  • Question 3 - Myelin sheath in the CNS is produced by? ...

    Incorrect

    • Myelin sheath in the CNS is produced by?

      Your Answer: Schwann cells

      Correct Answer: Oligodendrocytes

      Explanation:

      CNS myelin is produced by special cells called oligodendrocytes. PNS myelin is produced by Schwann cells. The two types of myelin are chemically different, but they both perform the same function — to promote efficient transmission of a nerve impulse along the axon.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      7.9
      Seconds

  • Question 4 - The choroid plexus: ...

    Correct

    • The choroid plexus:

      Your Answer: All are true

      Explanation:

      The choroid plexus is a vascular structure found in all cerebral ventricles. The functional unit of the choroid plexus, composed of a capillary, enveloped by a layer of differentiated ependymal epithelium. Unlike the capillaries that form the blood-brain barrier, choroid plexus capillaries are fenestrated and have no tight junctions. The endothelium, therefore, does not form a barrier to the movement of small molecules. Instead, the blood-CSF barrier at the choroid plexus is formed by the epithelial cells and the tight junctions that link them.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      10.8
      Seconds

  • Question 5 - In humans, the rate of CSF production per day is: ...

    Incorrect

    • In humans, the rate of CSF production per day is:

      Your Answer: 100-250 mls

      Correct Answer: 450-600 mls

      Explanation:

      CSF is produced around 20-25 ml per hour or 480-600ml per day.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      7.2
      Seconds

  • Question 6 - The primary sensory cortex is: ...

    Correct

    • The primary sensory cortex is:

      Your Answer: Brodmann area 3,1,2

      Explanation:

      A Brodmann area in the brain is defined by cytoarchitecture, histology and organization of cells:Primary somatosensory cortex is areas 3,1, and 2Primary Motor 4Premotor 6Primary Visual 17Primary Auditory 41Brocas 44

    • This question is part of the following fields:

      • Medicine
      • Neurology
      7.1
      Seconds

  • Question 7 - The basic taste “umami” is mediated by glutamate acting on a metabotropic receptor...

    Incorrect

    • The basic taste “umami” is mediated by glutamate acting on a metabotropic receptor named:

      Your Answer: Gustducin

      Correct Answer: mGluR4

      Explanation:

      Umami taste or savoury taste is one of the five basic tastes described as meaty or brothy. Umami taste receptors typically respond to Glutamate. Biochemical studies have identified the taste receptors responsible for the sense of umami as modified forms of mGluR4, mGluR1 and taste receptor type 1 (T1R1), all of which have been found in all regions of the tongue bearing taste buds.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      9.6
      Seconds

  • Question 8 - In a 60kg adult male with normal mean arterial pressure and oxygen consumption,...

    Incorrect

    • In a 60kg adult male with normal mean arterial pressure and oxygen consumption, what proportion of the cardiac output at rest goes to the brain?

      Your Answer: 20-25%

      Correct Answer: 10-15%

      Explanation:

      The rate of cerebral blood flow in the adult is typically 750 millilitres per minute, which is 10-15% of the cardiac output. On average around 13.9% of cardiac output is distributed to the brain.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      7.9
      Seconds

  • Question 9 - Activation of the cool receptor (CMR-1), causes: ...

    Incorrect

    • Activation of the cool receptor (CMR-1), causes:

      Your Answer: Efflux of Ca++

      Correct Answer: Influx of Ca++ & Na+

      Explanation:

      Cold and Menthol receptor 1 (CMR1) is a protein that in humans is encoded by TRPM8 gene. It is an ion channel which upon activation causes the influx of Na+ and Ca++ ions into the cell that leads to the depolarization and generation of an action potential.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      19.6
      Seconds

  • Question 10 - Sequence of events in formation of speech are: ...

    Incorrect

    • Sequence of events in formation of speech are:

      Your Answer: Insula---arcuate fasciculus---Wernicke's area---broca’s area---motor cortex---speech

      Correct Answer: Wernicke’s area---arcuate fasciculus---broca’s area---insula---motor cortex---speech

      Explanation:

      Wernicke’s area is located in the categorical hemisphere or left hemisphere in about 95% of right handed individuals and 60% of left handed individuals. It is involved in the comprehension or understanding of written and spoken language. In contrast Broca’s area is involved in production of language. Firstly, the language is accessed in the Wernicke’s area and these words are sent via the arcuate fasciculus to the Broca’s area, where instructions for articulation is generated. This is then sent from Broca’s are to the motor cortex for the articulation.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      9.8
      Seconds

  • Question 11 - The spinal cord receive its blood supply from the following arteries except: ...

    Incorrect

    • The spinal cord receive its blood supply from the following arteries except:

      Your Answer: 2 posterior spinal arteries

      Correct Answer: Lateral spinal artery

      Explanation:

      The spinal cord (SC) is supplied by the single anterior spinal artery which supplies the anterior two thirds of the SC and paired posterior spinal arteries supplying the posterior one third. Anastomoses between the spinal arteries supply the lateral column. These arteries originate near the cervico-occipital junction and therefore have a smaller calibre and often discontinue. Thus, they require reinforcement by segmental/radicular arteries which are branches of the ascending cervical artery, deep cervical artery, intercostal arteries, lumbar arteries and lateral sacral arteries

    • This question is part of the following fields:

      • Medicine
      • Neurology
      5.3
      Seconds

  • Question 12 - The pathway responsible for the discriminative aspect of pain, is called the: ...

    Incorrect

    • The pathway responsible for the discriminative aspect of pain, is called the:

      Your Answer: Spinoreticular tract

      Correct Answer: Neospinothalamic tract

      Explanation:

      The spinothalamic tract is an ascending or a sensory tract, responsible for transmission of pain and temperature. The neospinothalamic tract is responsible for fast pain or discriminative pain whereas the palaeospinothalamic tract is responsible for transmission of slow pain.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      12.1
      Seconds

  • Question 13 - Which part of the neuron has the highest concentration of sodium channels per...

    Incorrect

    • Which part of the neuron has the highest concentration of sodium channels per square millimetre of the cell membrane?

      Your Answer: Initial segment 350-500

      Correct Answer: Nodes of Ranvier

      Explanation:

      The nodes of Ranvier contain Na+/K+ ATPases, Na+/Ca2+ exchangers and a high density of Na+ channels. The estimated concentration of sodium channels in the node is of ∼1500/μm2.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      6.8
      Seconds

  • Question 14 - Which one of the following neurotransmitters is considered a monoamine? ...

    Incorrect

    • Which one of the following neurotransmitters is considered a monoamine?

      Your Answer: Acetylcholine

      Correct Answer: Dopamine

      Explanation:

      Monoamines are a class of neurotransmitters that include:

      1. Dopamine: A neurotransmitter involved in reward, motivation, and motor control.
      2. Norepinephrine: A neurotransmitter involved in arousal, attention, and stress responses.
      3. Serotonin: Although not listed in the options, it is another key monoamine involved in mood regulation.

      The other neurotransmitters listed are not monoamines:

      • Acetylcholine: This is a different type of neurotransmitter involved in muscle activation and various brain functions.
      • GABA (gamma-aminobutyric acid): This is the main inhibitory neurotransmitter in the central nervous system.
      • Glutamate: This is the main excitatory neurotransmitter in the central nervous system.
      • Glycine: An inhibitory neurotransmitter in the central nervous system.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      15.5
      Seconds

  • Question 15 - Afferent A δ fibers from nociceptors terminate primarily on neurons in which lamina:...

    Incorrect

    • Afferent A δ fibers from nociceptors terminate primarily on neurons in which lamina:

      Your Answer: III, IV, V, VI

      Correct Answer: I and V

      Explanation:

      Nociceptors are receptors of pain sensation. There are 2 primary afferent/sensory pain fibers which transmit impulses from the receptor to the CNS, specifically to the dorsal horn of the spinal cord. The two fibers are A δ and C fibers. The dorsal horn of the spinal cord is the relay centre for sensory information converging from the periphery. Grey matter of the dorsal horn is subdivided in to laminae based on cytoarchitecture. C fibers terminate in lamina II the substantia gelatinosa. A δ fibers terminate primarily in lamina I but some project more deeply to terminate in lamina V.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      4.5
      Seconds

  • Question 16 - Cold receptors are likely to be active at the following temperatures except? ...

    Correct

    • Cold receptors are likely to be active at the following temperatures except?

      Your Answer: 39 °C

      Explanation:

      Cold and Menthol receptor 1 (CMR1) is a protein that in humans is encoded by TRPM8 gene. It is primarily responsible for the detection of temperatures ranging from 8-28 C. It is an ion channel which upon activation causes the influx of Na+ and Ca+ ions into the cell that leads to the depolarization and generation of an action potential.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      8.4
      Seconds

  • Question 17 - Where is the M1 receptor mainly found? ...

    Incorrect

    • Where is the M1 receptor mainly found?

      Your Answer: Cardiac muscle

      Correct Answer: Sympathetic postganglionic neurons

      Explanation:

      M1 receptors are found in the sympathetic postganglionic neurons.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      5.9
      Seconds

  • Question 18 - Which of the following forms the language areas of the cerebral cortex? ...

    Incorrect

    • Which of the following forms the language areas of the cerebral cortex?

      Your Answer: Submarginal sulcus

      Correct Answer: All of the above

      Explanation:

      Broca’s area, Wernicke’s area, the submarginal sulcus and the angular gyrus all form the language areas of the cerebral cortex.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      22.7
      Seconds

  • Question 19 - Choose the correct answer: The cerebrocerebellum… ...

    Incorrect

    • Choose the correct answer: The cerebrocerebellum…

      Your Answer: Receives input via the corticopontocerebellar tracts in the middle cerebellar peduncle

      Correct Answer: All options are correct

      Explanation:

      Cerebrocerebellum is comprised of two lateral regions, the cerebellar hemispheres and communicates with the cerebral cortex. It is principally responsible for controlling coordination of movement. Three fiber bundles carry the input and output of the cerebellum. There are three cerebellar peduncles with different connections and functions. The three are mainly, superior, middle and inferior. The superior cerebellar peduncle is also known as the “Brachium conjunctivum”. It predominantly contains efferent fibers from the cerebellar nuclei, as well as some afferents from the spinocerebellar tract. The efferent pathways include cerebellorubral, dentatothalamic, and fastigioreticular fibers. These are tracts projecting from the deep cerebellar nuclei to the thalamus and red nucleus. The middle cerebellar peduncle connects to the pontine nucleus and the dorsal spinocerebellar tracts run through the superior cerebellar peduncle

    • This question is part of the following fields:

      • Medicine
      • Neurology
      13.4
      Seconds

  • Question 20 - The nucleus ambiguus: ...

    Incorrect

    • The nucleus ambiguus:

      Your Answer: Regulates phonation via somatic motor supply in CN XII

      Correct Answer: Regulates swallowing, phonation and parasympathetic supply to the heart via CN IX, X and XI

      Explanation:

      Nucleus Ambiguus is a group of large motor neurons found deep in the medullary reticular formation. It contains cell bodies of nerves that are responsible for the innervation of muscles of speech and swallowing which are located in the soft palate, pharynx and larynx. Additionally, it contains cholinergic preganglionic parasympathetic neurons of the heart via CN X, IX and XI

    • This question is part of the following fields:

      • Medicine
      • Neurology
      9
      Seconds

  • Question 21 - Dynein proteins transmit polypeptides/proteins in which direction? ...

    Incorrect

    • Dynein proteins transmit polypeptides/proteins in which direction?

      Your Answer: From cell body to axonal terminals (anterograde)

      Correct Answer: From axons terminals to cell body (retrograde)

      Explanation:

      The majority of axonal proteins are synthesised in the cell body and transported along the axons. Microtubules run along the length of the axon and provide tracks for transportation. Kinesin and Dynein are motor proteins that transport proteins and other organelles. Kinesin moves forward or anterograde transport from cell body to axon, whereas Dynein moves retrograde from axon to cell body.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      5.8
      Seconds

  • Question 22 - Which receptor type is associated with the inhibition of pancreatic endocrine secretion? ...

    Incorrect

    • Which receptor type is associated with the inhibition of pancreatic endocrine secretion?

      Your Answer: Α1

      Correct Answer: Α2

      Explanation:

      The activation of alpha 2-adrenergic receptors in pancreatic beta-cells works by inhibiting the secretion of insulin.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      12.1
      Seconds

  • Question 23 - Select the correct pairing regarding the surface of the cerebral hemispheres. ...

    Correct

    • Select the correct pairing regarding the surface of the cerebral hemispheres.

      Your Answer: Parietal lobe : primary somatosensory cortex

      Explanation:

      Parietal lobe: The primary somatosensory cortex is located in the postcentral gyrus of the parietal lobe. It is responsible for processing sensory information from the body.

      Frontal lobe: The primary motor cortex is located in the precentral gyrus of the frontal lobe. The frontal lobe also contains the premotor cortex, which is involved in planning movements. The primary visual cortex is located in the occipital lobe, not the frontal lobe.

      Temporal lobe: The primary auditory cortex is located in the superior temporal gyrus of the temporal lobe. The primary motor and premotor cortices are located in the frontal lobe, not the temporal lobe.

      Occipital lobe: The primary visual cortex is located in the occipital lobe. The primary auditory cortex is located in the temporal lobe, not the occipital lobe.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      5
      Seconds

  • Question 24 - The tectum as part of the Midbrain contains which structure important in visual...

    Incorrect

    • The tectum as part of the Midbrain contains which structure important in visual reflexes.

      Your Answer: Red nucleus

      Correct Answer: Superior colliculus

      Explanation:

      The tectum is a part of the midbrain, specifically, the dorsal part of the midbrain. The tectum consists of the superior and inferior colliculi. The superior colliculus is involved in preliminary visual processing and control of eye movement.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      5.3
      Seconds

  • Question 25 - The small opening in the cochlea through which the upper scala vestibuli and...

    Incorrect

    • The small opening in the cochlea through which the upper scala vestibuli and lower scala tympani communicates is called the:

      Your Answer: Scala media

      Correct Answer: Helicotrema

      Explanation:

      The helicotrema is the part of cochlear labyrinth where the scala tympani and the scala vestibuli meet.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      7.8
      Seconds

  • Question 26 - An exaggerated response to a noxious stimulus is called: ...

    Incorrect

    • An exaggerated response to a noxious stimulus is called:

      Your Answer: Hyperesthesia

      Correct Answer: Hyperalgesia

      Explanation:

      Allodynia is the sensation of pain following non-painful stimulation.

      Hyperalgesia is enhanced intensity of pain sensation.

      Causalgia is a constant burning pain resulting from peripheral nerve injury.

      Hyperesthesia is the abnormal increase in sensitivity to stimuli of sense.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      4.2
      Seconds

  • Question 27 - Where do the meningeal veins lie? ...

    Incorrect

    • Where do the meningeal veins lie?

      Your Answer: Cerebellum

      Correct Answer: Endosteal layer of the dura

      Explanation:

      Meningeal veins lie in the endosteal layer of the dura. The veins lie lateral to the arteries.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      21.9
      Seconds

  • Question 28 - An example of cholinergic autonomic neurons are: ...

    Incorrect

    • An example of cholinergic autonomic neurons are:

      Your Answer: Sympathetic postganglionic neurons that causes relaxation of the detrusor muscle of the bladder.

      Correct Answer: Sympathetic postganglionic neurons that innervate sweat glands.

      Explanation:

      All preganglionic neurons in both the sympathetic and parasympathetic nervous system secrete acetylcholine. The postganglionic neurotransmitter of the parasympathetic nervous system in all neurons is acetylcholine. Postganglionic fibers of the sympathetic nervous system mainly secrete Noradrenalin and Adrenalin but at sweat glands and erector pili muscles the postganglionic neurotransmitter is acetylcholine.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      8.9
      Seconds

  • Question 29 - Which receptor type is associated with bronchial muscle relaxation? ...

    Incorrect

    • Which receptor type is associated with bronchial muscle relaxation?

      Your Answer: M2

      Correct Answer: β2

      Explanation:

      β2-adrenoceptors are widely distributed in the respiratory tract. When they are activated, an intracellular response induces the activation of cyclic AMP; this, in turn, produces airway relaxation through phosphorylation of muscle regulatory proteins and modification of cellular Ca2+concentrations.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      10.1
      Seconds

  • Question 30 - Regarding taste threshold and intensity discrimination: ...

    Incorrect

    • Regarding taste threshold and intensity discrimination:

      Your Answer:

      Correct Answer: 30% change in concentration of substance tasted is necessary before an intensity difference can be detected

      Explanation:

      The ability of humans to differentiate differences in intensity of taste is poor. A 30% change in the concentration of the substance being tasted is required before an intensity difference is perceived.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Medicine (13/29) 45%
Neurology (13/29) 45%
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