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  • Question 1 - When oxygen supply is restored, lactate formed during anaerobic metabolism is converted back...

    Correct

    • When oxygen supply is restored, lactate formed during anaerobic metabolism is converted back to?

      Your Answer: Pyruvate

      Explanation:

      During intense exercise, when the rate of demand for energy is high, glucose is broken down and oxidized to pyruvate, and lactate is then produced from the pyruvate faster than the body can process it, causing lactate concentrations to rise. The resulting lactate can be used in two ways:1. Oxidation back to pyruvate by well-oxygenated muscle cells, heart cells, and brain cells. Pyruvate is then directly used to fuel the Krebs cycle2. Conversion to glucose via gluconeogenesis in the liver and release back into circulation.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      7
      Seconds
  • Question 2 - Which lipoprotein is responsible for lowering of plasma lipids? ...

    Correct

    • Which lipoprotein is responsible for lowering of plasma lipids?

      Your Answer: HDL

      Explanation:

      High-density lipoproteins (HDL) are one of the five major groups of lipoproteins. Lipoproteins are complex particles composed of multiple proteins which transport all fat molecules (lipids) around the body within the water outside cells. Unlike the larger lipoprotein particles which deliver fat molecules to cells, HDL particles remove fat molecules from cells.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      4.5
      Seconds
  • Question 3 - Which of the following refers to the process of decoding messenger RNA into...

    Correct

    • Which of the following refers to the process of decoding messenger RNA into an amino acid sequence?

      Your Answer: Translation

      Explanation:

      Messenger RNA (mRNA) is decoded in a ribosome, outside the nucleus, to produce a specific amino acid chain, or polypeptide. This is known as translation and follows after the process transcription of DNA to RNA in the cell’s nucleus.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      9.1
      Seconds
  • Question 4 - What catalyses the conversion of adenosine to inosine? ...

    Correct

    • What catalyses the conversion of adenosine to inosine?

      Your Answer: Adenosine deaminase

      Explanation:

      Adenosine deaminase (ADA) is an enzyme involved in purine metabolism. It is needed for the breakdown of adenosine from food and for the turnover of nucleic acids in tissues. ADA irreversibly deaminates adenosine, converting it to the related nucleoside inosine by the substitution of the amino group for a keto group.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      11
      Seconds
  • Question 5 - The energy needed for glycogen synthesis comes from which compound? ...

    Incorrect

    • The energy needed for glycogen synthesis comes from which compound?

      Your Answer: ATP

      Correct Answer: UTP

      Explanation:

      Glycogen synthesis is, unlike its breakdown, endergonic—it requires the input of energy. Energy for glycogen synthesis comes from uridine triphosphate (UTP)

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      7.2
      Seconds
  • Question 6 - Which enzyme hydrolyses triglycerides in lipoproteins into free fatty acids for storage in...

    Correct

    • Which enzyme hydrolyses triglycerides in lipoproteins into free fatty acids for storage in fat cells?

      Your Answer: Lipoprotein lipase

      Explanation:

      Lipoprotein lipase is a water-soluble enzyme that hydrolyses triglycerides in lipoproteins, such as those found in chylomicrons and very low-density lipoproteins (VLDL), into two free fatty acids and one monoacylglycerol molecule.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      11.3
      Seconds
  • Question 7 - Which enzyme deficiency can lead to ammonia intoxication? ...

    Correct

    • Which enzyme deficiency can lead to ammonia intoxication?

      Your Answer: Ornithine transcarbamylase

      Explanation:

      Ornithine transcarbamylase deficiency also known as OTC deficiency is the most common urea cycle disorder in humans. Ornithine transcarbamylase, the defective enzyme in this disorder is the final enzyme in the proximal portion of the urea cycle, responsible for converting carbamoyl phosphate and ornithine into citrulline. OTC deficiency is inherited in an X-linked recessive manner, meaning males are more commonly affected than females.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      20.1
      Seconds
  • Question 8 - Which of the following groups are purines? ...

    Correct

    • Which of the following groups are purines?

      Your Answer: Adenine, guanine, hypoxanthine

      Explanation:

      There are many naturally occurring purines. They include the nucleobases, adenine and guanine. Other notable purines are hypoxanthine, xanthine), theobromine, caffeine, uric acid and isoguanine.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      12.1
      Seconds
  • Question 9 - The conversion of fructose to fructose 1-phosphate is catalysed by: ...

    Correct

    • The conversion of fructose to fructose 1-phosphate is catalysed by:

      Your Answer: Fructokinase

      Explanation:

      The first step in the metabolism of fructose is the phosphorylation of fructose to fructose 1-phosphate by fructokinase.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      11
      Seconds
  • Question 10 - Where is the major site of purine synthesis? ...

    Correct

    • Where is the major site of purine synthesis?

      Your Answer: Liver

      Explanation:

      The major site of purine synthesis is in the liver. Purines are biologically synthesized as nucleotides and in particular as ribotides.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      2.2
      Seconds
  • Question 11 - The largest energy reserves among both lean and obese subjects are from? ...

    Correct

    • The largest energy reserves among both lean and obese subjects are from?

      Your Answer: Fatty acids

      Explanation:

      The energy required for sustained exercise is provided by the oxidation of two fuels, glucose stored as glycogen in the liver and muscle, and long-chain fatty acids, stored as adipose tissue triglycerides. The latter provides the largest energy reserve in the body.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      6.3
      Seconds
  • Question 12 - The enzyme that catalyses the final step in glycogen synthesis is: ...

    Correct

    • The enzyme that catalyses the final step in glycogen synthesis is:

      Your Answer: Glycogen synthase

      Explanation:

      Glycogen synthase is a key enzyme in glycogenesis, the conversion of glucose into glycogen. This enzyme combines excess glucose residues one by one into a polymeric chain for storage as glycogen.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      5.3
      Seconds
  • Question 13 - During anaerobic glycolysis, the net production of ATP is: ...

    Correct

    • During anaerobic glycolysis, the net production of ATP is:

      Your Answer: 2

      Explanation:

      Anaerobic glycolysis is the transformation of glucose to lactate when limited amounts of oxygen (O2) are available. Anaerobic glycolysis is only an effective means of energy production during short, intense exercise, providing energy for a period ranging from 10 seconds to 2 minutes. It produces 2 ATP molecules per glucose molecule.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      2.9
      Seconds
  • Question 14 - What does a deficiency of adenosine deaminase lead to? ...

    Correct

    • What does a deficiency of adenosine deaminase lead to?

      Your Answer: SCID

      Explanation:

      Severe combined immunodeficiency, SCID, also known as alymphocytosis, Glanzmann–Riniker syndrome, severe mixed immunodeficiency syndrome, and thymic alymphoplasia,[1] is a rare genetic disorder characterized by the disturbed development of functional T cells and B cells. Most cases of SCID are due to mutations in the gene encoding the common gamma chain (γc), a protein that is shared by the receptors for interleukins. The second most common form of SCID after X-SCID is caused by a defective enzyme, adenosine deaminase (ADA), necessary for the breakdown of purines.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      16.8
      Seconds
  • Question 15 - Which of the following is an example of a ketone body? ...

    Correct

    • Which of the following is an example of a ketone body?

      Your Answer: Acetoacetate

      Explanation:

      Ketone bodies are three water-soluble molecules (acetoacetate, beta-hydroxybutyrate, and their spontaneous breakdown product, acetone) that are produced by the liver from fatty acids during periods of low food intake (fasting), carbohydrate restrictive diets, starvation, prolonged intense exercise, alcoholism or in untreated (or inadequately treated) type 1 diabetes mellitus.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      10.6
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Medicine (14/15) 93%
Metabolism (14/15) 93%
Passmed