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Question 1
Correct
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In addition to its role in digestion and absorption of fats, bile:
Your Answer: Is the major excretory route for lipid-soluble waste products
Explanation:The end product of haem metabolism is bilirubin and jaundice is caused by increased bilirubin levels in the blood. Gallstones are mainly caused by cholesterol and bile pigments. Bile is the main route of excretion for lipid soluble waste products whereas urine is the main route of excretion of water soluble waste products.
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This question is part of the following fields:
- Gastrointestinal
- Medicine
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Question 2
Correct
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The oesophagus is lined by
Your Answer: Stratified squamous epithelium
Explanation:The wall of the oesophagus from the lumen outwards consists of mucosa, submucosa (connective tissue), layers of muscle fibers between layers of fibrous tissue, and an outer layer of connective tissue. The mucosa is a stratified squamous epithelium of around three layers of squamous cells, which contrasts to the single layer of columnar cells of the stomach. The transition between these two types of epithelium is visible as a zig-zag line. Most of the muscle is smooth muscle although striated muscle predominates in its upper two thirds.
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This question is part of the following fields:
- Gastrointestinal
- Medicine
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Question 3
Incorrect
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The end product of trehalase action on oligosaccharides is
Your Answer: Two fructose molecules
Correct Answer: Two glucose molecules
Explanation:Disaccharides are glycoside hydrolases, enzymes that break down certain types of sugars called disaccharides into simpler sugars called monosaccharides.Examples of disaccharides:Lactase (breaks down lactose into glucose and galactose)Maltase (breaks down maltose into 2 glucoses)Sucrase (breaks down sucrose into glucose and fructose)Trehalase (breaks down trehalose into 2 glucoses)
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This question is part of the following fields:
- Gastrointestinal
- Medicine
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Question 4
Correct
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With regard to carbohydrate absorption, which sodium-dependent glucose transporter (SGLT) is responsible for the uptake of dietary glucose from the gut?
Your Answer: SGLT 1
Explanation:SGLT- Sodium-dependent glucose cotransporter or sodium-glucose linked transporter are family of proteins of different types. SGLT1 transporter is found in the intestinal mucosa of the small intestine.
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This question is part of the following fields:
- Gastrointestinal
- Medicine
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Question 5
Correct
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The chief cells of the stomach secrete which of the following?
Your Answer: Pepsinogens
Explanation:A gastric chief cell (or peptic cell, or gastric zymogenic cell) is a type of cell in the stomach that releases pepsinogen and gastric lipase.
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This question is part of the following fields:
- Gastrointestinal
- Medicine
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Question 6
Correct
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What is the function of migrating motor complex
Your Answer: Clears the gut of luminal contents in preparation of the next meal
Explanation:Migrating motor complexes (MMC) are waves of electrical activity that sweep through the intestines in a regular cycle during fasting. These motor complexes trigger peristaltic waves, which facilitate transportation of indigestible substances such as bone, fiber, and foreign bodies from the stomach, through the small intestine, past the ileocecal sphincter, and into the colon. The MMC occurs every 90–120 minutes during the interdigestive phase (between meals), and is responsible for the rumbling experienced when hungry. It also serves to transport bacteria from the small intestine to the large intestine, and to inhibit the migration of colonic bacteria into the terminal ileum.
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This question is part of the following fields:
- Gastrointestinal
- Medicine
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Question 7
Incorrect
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Which of the following forms an important constituent of the brush border on the microvilli of the intestinal epithelium?
Your Answer: Crypts
Correct Answer: Hydrolases
Explanation:There are certain enzymes which are part of the brush border cells including hydrolases also known as the brush border hydrolases. They perform the final step in digestion of certain nutrients.
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This question is part of the following fields:
- Gastrointestinal
- Medicine
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Question 8
Incorrect
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Where does most fat digestion begin?
Your Answer: Ileum
Correct Answer: Duodenum
Explanation:Digestion of some fats can begin in the mouth where lingual lipase breaks down some short chain lipids into diglycerides. However fats are mainly digested in the small intestine (in the duodenum). The presence of fat in the small intestine produces hormones that stimulate the release of pancreatic lipase from the pancreas and bile from the liver which helps in the emulsification of fats for absorption of fatty acids.
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This question is part of the following fields:
- Gastrointestinal
- Medicine
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Question 9
Incorrect
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Interruption of the entero-hepatic circulation causes:
Your Answer: General malabsorption
Correct Answer: The amount of fat in the stool to be increased
Explanation:Enterohepatic circulation refers to the circulation of biliary acids, bilirubin, drugs, or other substances from the liver to the bile, followed by entry into the small intestine, absorption by the enterocyte and transport back to the liver. One of the causes of the interruption of enterohepatic circulation is the resection of the ileum where fat is mainly absorbed. Fat malabsorption results in increased fat in stools. Pale stools and dark urine is caused by obstruction of the biliary ductal system especially the common bile duct where urobilin and stercobilin are formed.
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This question is part of the following fields:
- Gastrointestinal
- Medicine
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Question 10
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