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  • Question 1 - What landmark divides the frontal and parietal lobes? ...

    Incorrect

    • What landmark divides the frontal and parietal lobes?

      Your Answer:

      Correct Answer: Central sulcus

      Explanation:

      The central sulcus divides the frontal lobe from the parietal lobe. It contains the motor cells for the movement function of the body.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 2 - Which one of the following neurotransmitters is considered a monoamine? ...

    Incorrect

    • Which one of the following neurotransmitters is considered a monoamine?

      Your Answer:

      Correct Answer: Acetylcholine

      Explanation:

      Acetylcholine is a major neurotransmitter in the peripheral nervous system. Monoamine neurotransmitters contain only one amino group joined to an aromatic ring. Acetylcholine is produced from acetyl-CoA and choline.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 3 - In which cell would you find a Nissl body? ...

    Incorrect

    • In which cell would you find a Nissl body?

      Your Answer:

      Correct Answer: Bipolar neuron

      Explanation:

      Nissl bodies are the structures of protein synthesis in neurones. They are granular bodies of Rough Endoplasmic Reticulum and ribosomes. Astrocytes, Microglia, Schwann cell, oligodendrocytes are collectively known as glia or supporting cells of the nervous system.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 4 - In humans, the rate of CSF production per day is: ...

    Incorrect

    • In humans, the rate of CSF production per day is:

      Your Answer:

      Correct Answer: 450-600 mls

      Explanation:

      CSF is produced around 20-25 ml per hour or 480-600ml per day.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 5 - Wernicke’s area: ...

    Incorrect

    • Wernicke’s area:

      Your Answer:

      Correct Answer: Is concerned with comprehension of auditory and visual information

      Explanation:

      Wernicke’s area is located in the categorical hemisphere or left hemisphere in about 95% of right handed individuals and 60% of left handed individuals. It is involved in the comprehension or understanding of written and spoken language. In contrast Broca’s area is involved in production of language.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 6 - Select the correct pairing regarding the surface of the cerebral hemispheres. ...

    Incorrect

    • Select the correct pairing regarding the surface of the cerebral hemispheres.

      Your Answer:

      Correct Answer: Parietal lobe : primary somatosensory cortex

      Explanation:

      Right homonymous hemianopia is due to a lesion or pressure on the left optic tract.
      Total blindness of the left eye is due to a complete occlusion of the left optic nerve.
      Bipolar hemianopia is due to a midline chiasmal lesion.
      Left nasal hemianopia due to a lesion involving the left perichiasmal area.
      Right homonymous inferior quadrantanopia is due to involvement of the lower left optic radiations.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 7 - The brainstem reticular formation, consists of which important control system responsible for consciousness...

    Incorrect

    • The brainstem reticular formation, consists of which important control system responsible for consciousness and sleep?

      Your Answer:

      Correct Answer: RAS reticular activating system

      Explanation:

      The reticular formation is a set of interconnected nuclei that are located along the brainstem. Reticular activating system (RAS) is a set of connected nuclei in the brain that is responsible for regulating wakefulness and sleep wake transitions and is the most influential component in the reticular formation.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 8 - The main reason for the prolonged effect of the withdrawal reflex is: ...

    Incorrect

    • The main reason for the prolonged effect of the withdrawal reflex is:

      Your Answer:

      Correct Answer: Multiple connections between afferent and efferent neurons

      Explanation:

      The withdrawal reflex is a spinal reflex that protects the body from harmful stimuli. Spinal reflexes are mostly monosynaptic and are mediated by a simple reflex arc. Withdrawal reflex is mediated by a polysynaptic reflex resulting in stimulation of many motor neurons in order to establish a quick and prolonged response.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 9 - Which of the following correctly describes stages in the formation of CSF? ...

    Incorrect

    • Which of the following correctly describes stages in the formation of CSF?

      Your Answer:

      Correct Answer: All of the above

      Explanation:

      All the above are true for the formation of CSF

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 10 - Which enzyme is responsible for the removal of acetylcholine from the synapse? ...

    Incorrect

    • Which enzyme is responsible for the removal of acetylcholine from the synapse?

      Your Answer:

      Correct Answer: Acetylcholinesterase

      Explanation:

      Acetylcholinesterase is the enzyme that is responsible for breaking down acetylcholine into choline and acetate. Both of these molecules are transported back to the presynaptic neuron to be synthesized again. This enzyme is attached to the collagen fibers of the basement membrane in the synaptic cleft.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 11 - The Afferent neuron that supplies all sensory elements of the muscle spindle is...

    Incorrect

    • The Afferent neuron that supplies all sensory elements of the muscle spindle is what type of sensory neuron?

      Your Answer:

      Correct Answer: Ia

      Explanation:

      Muscle spindle is supplied by both sensory and motor nerves. Sensory supply is Type Ia fibers whereas motor supply is gamma motor neurone.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 12 - Regarding taste threshold and intensity discrimination: ...

    Incorrect

    • Regarding taste threshold and intensity discrimination:

      Your Answer:

      Correct Answer: 30% change in concentration of substance tasted is necessary before an intensity difference can be detected

      Explanation:

      The ability of humans to differentiate differences in intensity of taste is poor. A 30% change in the concentration of the substance being tasted is required before an intensity difference is perceived.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 13 - The ependyma fuse with which of the following to from the choroid plexus?...

    Incorrect

    • The ependyma fuse with which of the following to from the choroid plexus?

      Your Answer:

      Correct Answer: Tela choroidea

      Explanation:

      The choroid plexus produces the cerebrospinal fluid (CSF) in the ventricles of the brain. It consists of modified ependymal cells. Tela choroidea is a region of pia mater of the meninges and underlying ependyma that’s a part of the choroid plexus. It is a very thin layer of the connective tissue of pia mater that overlies and covers the ependyma.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 14 - Transportation of proteins from the cell body to axonal terminals is known as:...

    Incorrect

    • Transportation of proteins from the cell body to axonal terminals is known as:

      Your Answer:

      Correct Answer: Axoplasmic flow

      Explanation:

      Transportation of proteins from the cell body to axonal terminals is known as axoplasmic, axonal flow or Axonal transport.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 15 - Regarding the formation of CSF, which of the following is true? ...

    Incorrect

    • Regarding the formation of CSF, which of the following is true?

      Your Answer:

      Correct Answer: Its composition resembles that of brain ECF

      Explanation:

      In normal adults CSF volume is around 125ml to 150ml. Turnover of entire volume of cerebrospinal fluid a day is about 3 to 4 times a day. Composition of CSF is similar to that of plasma except that CSF is nearly protein-free compared with plasma and has a different electrolyte level. About 80% of CSF is produced by the choroid plexus. It is also produced by a single layer of column shaped ependymal cells. The composition and rate of CSF generation depends on several factors and is influenced by hormones and the content and pressure of blood and CSF.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 16 - The nucleus ambiguus: ...

    Incorrect

    • The nucleus ambiguus:

      Your Answer:

      Correct Answer: Regulates swallowing, phonation and parasympathetic supply to the heart via CN IX, X and XI

      Explanation:

      Nucleus Ambiguus is a group of large motor neurons found deep in the medullary reticular formation. It contains cell bodies of nerves that are responsible for the innervation of muscles of speech and swallowing which are located in the soft palate, pharynx and larynx. Additionally, it contains cholinergic preganglionic parasympathetic neurons of the heart via CN X, IX and XI

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 17 - A lesion that interrupts one optic nerve causes blindness: ...

    Incorrect

    • A lesion that interrupts one optic nerve causes blindness:

      Your Answer:

      Correct Answer: In the eye on the same side as the optic nerve

      Explanation:

      The optic nerve on each side contains medial and lateral fibers originating from the retina. Medial fibers cross at the optic chiasm and become the optic tract ending in the visual cortex of the occipital lobe. If there is a lesion interrupting the “optic nerve” on one side, the same side eye will be completely blind.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 18 - In Argyll Robertson pupils… ...

    Incorrect

    • In Argyll Robertson pupils…

      Your Answer:

      Correct Answer: All of the above

      Explanation:

      Argyll Robertson pupils are bilaterally small pupils that accommodate or reduce in size near an object but do not react to light. They do not constrict when exposed to bright light. They are a highly specific sign of neurosyphilis but may be seen in diabetic neuropathy as well.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 19 - Which part of the neuron has the highest concentration of sodium channels per...

    Incorrect

    • Which part of the neuron has the highest concentration of sodium channels per square millimetre of the cell membrane?

      Your Answer:

      Correct Answer: Nodes of Ranvier

      Explanation:

      The nodes of Ranvier contain Na+/K+ ATPases, Na+/Ca2+ exchangers and a high density of Na+ channels. The estimated concentration of sodium channels in the node is of ∼1500/μm2.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 20 - Choose the correct answer: fibers in the superior cerebellar peduncle: ...

    Incorrect

    • Choose the correct answer: fibers in the superior cerebellar peduncle:

      Your Answer:

      Correct Answer: Are mainly ventral spinocerebellar tracts from the cerebellar nuclei to the thalamus and red nucleus

      Explanation:

      There are three cerebellar peduncles with different connections and functions. The three are mainly, superior, middle and inferior. The superior cerebellar peduncle is also known as the “Brachium conjunctivum”. It predominantly contains efferent fibers from the cerebellar nuclei, as well as some afferents from the spinocerebellar tract. The efferent pathways include cerebellorubral, dentatothalamic, and fastigioreticular fibers. These are tracts projecting from the deep cerebellar nuclei to the thalamus and red nucleus. The middle cerebellar peduncle connects to the pontine nucleus and the dorsal spinocerebellar tracts run through the superior cerebellar peduncle.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 21 - In the olfactory pathway: Mitral cells project to five regions of the olfactory...

    Incorrect

    • In the olfactory pathway: Mitral cells project to five regions of the olfactory cortex. Which one of the following is not one of the five regions?

      Your Answer:

      Correct Answer: Posterior olfactory nucleus

      Explanation:

      The olfactory system contains peripheral and central divisions which are connected by transduction structures. Peripheral division consists mainly of the nostrils, ethmoid bone, nasal cavity, and the olfactory epithelium. Olfactory neurons are receptor cells in the epithelium that detect odour molecules dissolved in the mucus and transmit information about the odour to the brain in a process called sensory transduction. Olfactory nerves and fibers transmit information about odours from the peripheral olfactory system to the central olfactory system of the brain. The main olfactory bulb transmits pulses to both mitral and tufted cells, which help determine odour concentration. These cells also note differences between highly similar odours and use that data to aid in later recognition. The cells are different with the mitral having low firing-rates and being easily inhibited by neighbouring cells, while tufted have high rates of firing and are more difficult to inhibit. The uncus houses the olfactory cortex which includes the piriform cortex, amygdala, olfactory tubercle, and para-hippocampal gyrus. Entorhinal cortex is an area of middle temporal lobe that has connection with the para-hippocampal gyrus.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 22 - Which one of the following cells originates from a monocyte and resembles a...

    Incorrect

    • Which one of the following cells originates from a monocyte and resembles a macrophage?

      Your Answer:

      Correct Answer: Microglia

      Explanation:

      Microglia act as the macrophages of the central nervous system, and they contribute to innate and adaptive immune responses. Studies have shown that microglial cells recognize monocyte antigens, and there are similarities between them that demonstrate that they originate from these monocytes.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 23 - In the basal ganglia, the Lentiform nucleus is formed by which two nuclei?...

    Incorrect

    • In the basal ganglia, the Lentiform nucleus is formed by which two nuclei?

      Your Answer:

      Correct Answer: Putamen and Globus pallidus

      Explanation:

      The Basal Ganglia are composed of the following structures: Caudate, putamen, Globus pallidus, subthalamic nucleus and substantia nigra. The lentiform nucleus comprises of the putamen and the Globus pallidus.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 24 - In a 60kg adult male with normal mean arterial pressure and oxygen consumption,...

    Incorrect

    • In a 60kg adult male with normal mean arterial pressure and oxygen consumption, what proportion of the cardiac output at rest goes to the brain?

      Your Answer:

      Correct Answer: 10-15%

      Explanation:

      The rate of cerebral blood flow in the adult is typically 750 millilitres per minute, which is 10-15% of the cardiac output. On average around 13.9% of cardiac output is distributed to the brain.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 25 - Choose the correct answer: The cerebrocerebellum… ...

    Incorrect

    • Choose the correct answer: The cerebrocerebellum…

      Your Answer:

      Correct Answer: All options are correct

      Explanation:

      Cerebrocerebellum is comprised of two lateral regions, the cerebellar hemispheres and communicates with the cerebral cortex. It is principally responsible for controlling coordination of movement. Three fiber bundles carry the input and output of the cerebellum. There are three cerebellar peduncles with different connections and functions. The three are mainly, superior, middle and inferior. The superior cerebellar peduncle is also known as the “Brachium conjunctivum”. It predominantly contains efferent fibers from the cerebellar nuclei, as well as some afferents from the spinocerebellar tract. The efferent pathways include cerebellorubral, dentatothalamic, and fastigioreticular fibers. These are tracts projecting from the deep cerebellar nuclei to the thalamus and red nucleus. The middle cerebellar peduncle connects to the pontine nucleus and the dorsal spinocerebellar tracts run through the superior cerebellar peduncle

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 26 - The consensual light reflex is co-ordinated mainly in the: ...

    Incorrect

    • The consensual light reflex is co-ordinated mainly in the:

      Your Answer:

      Correct Answer: Edinger-Westphal nucleus

      Explanation:

      The consensual light reflex occurs when an individual’s right eye is shielded and light shines into the left eye, constriction of the right pupil will occur, as well as the left. This is because the afferent signal sent through one optic nerve connects to the Edinger-Westphal nucleus, whose axons run to both the right and the left oculomotor nerves.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 27 - The thalamus is a large collection of neuronal groups within the diencephalons which...

    Incorrect

    • The thalamus is a large collection of neuronal groups within the diencephalons which participates in:

      Your Answer:

      Correct Answer: Sensory, motor and limbic

      Explanation:

      The thalamus has multiple functions. It is the relay station for every sensory system (except olfactory, regulates the sleep-wake cycle and consciousness and also relays motor information.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 28 - What is the most abundant cell type in the central nervous system called?...

    Incorrect

    • What is the most abundant cell type in the central nervous system called?

      Your Answer:

      Correct Answer: Astrocyte

      Explanation:

      Astrocytes are the supporting cells of the central nervous system. There are two types; the fibrous type is found in the white matter and the protoplasmic type in the grey matter. They are the most abundant cell type in the CNS.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 29 - The reticular formation occupies which area of the brain? ...

    Incorrect

    • The reticular formation occupies which area of the brain?

      Your Answer:

      Correct Answer: Medulla and midbrain

      Explanation:

      The reticular formation is a set of interconnected nuclei that are located along the brainstem.

    • This question is part of the following fields:

      • Neuro-anatomy
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  • Question 30 - Which one of the following nerve fibers has the fastest conduction velocity? ...

    Incorrect

    • Which one of the following nerve fibers has the fastest conduction velocity?

      Your Answer:

      Correct Answer: α fiber

      Explanation:

      α nerve fibers are characterized by being highly myelinated, which confers them with fast conduction properties. They innervate extrafusal skeletal muscle fibers, and their conduction velocity is between 80-120 m/s.

    • This question is part of the following fields:

      • Neuro-anatomy
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      Seconds

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