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  • Question 1 - In which cell would you find a Nissl body? ...

    Incorrect

    • In which cell would you find a Nissl body?

      Your Answer: Schwann cell

      Correct Answer: Bipolar neuron

      Explanation:

      Nissl bodies are the structures of protein synthesis in neurones. They are granular bodies of Rough Endoplasmic Reticulum and ribosomes. Astrocytes, Microglia, Schwann cell, oligodendrocytes are collectively known as glia or supporting cells of the nervous system.

    • This question is part of the following fields:

      • Neuro-anatomy
      4.1
      Seconds

  • Question 2 - The primary auditory cortex is: ...

    Incorrect

    • The primary auditory cortex is:

      Your Answer: Brodmann area 44

      Correct Answer: Brodmann area 41

      Explanation:

      A Brodmann area in the brain is defined by cytoarchitecture, histology and organization of cells:
      Primary Sensory 3,1,2
      Primary Motor 4
      Premotor 6
      Primary Visual 17
      Primary Auditory 41
      Brocas 44

    • This question is part of the following fields:

      • Neuro-anatomy
      6.4
      Seconds

  • Question 3 - Activation of the cool receptor (CMR-1), causes: ...

    Incorrect

    • Activation of the cool receptor (CMR-1), causes:

      Your Answer: Efflux of Ca++

      Correct Answer:

      Explanation:

      Cold and Menthol receptor 1 (CMR1) is a protein that in humans is encoded by TRPM8 gene. It is an ion channel which upon activation causes the influx of Na+ and Ca++ ions into the cell that leads to the depolarization and generation of an action potential.

    • This question is part of the following fields:

      • Neuro-anatomy
      6.5
      Seconds

  • Question 4 - The choroid plexus: ...

    Incorrect

    • The choroid plexus:

      Your Answer: Its endothelial cells have no tight junctions

      Correct Answer: All are true

      Explanation:

      The choroid plexus is a vascular structure found in all cerebral ventricles. The functional unit of the choroid plexus, composed of a capillary, enveloped by a layer of differentiated ependymal epithelium. Unlike the capillaries that form the blood-brain barrier, choroid plexus capillaries are fenestrated and have no tight junctions. The endothelium, therefore, does not form a barrier to the movement of small molecules. Instead, the blood-CSF barrier at the choroid plexus is formed by the epithelial cells and the tight junctions that link them.

    • This question is part of the following fields:

      • Neuro-anatomy
      10.8
      Seconds

  • Question 5 - Choose the correct answer: The interposed nuclei… ...

    Incorrect

    • Choose the correct answer: The interposed nuclei…

      Your Answer: All of the above

      Correct Answer: Are the emboliform and globose nuclei in the paravermis

      Explanation:

      The interposed nuclei are a part of deep cerebellar complex and are composed of the globose nucleus and the emboliform nucleus. It receives afferent fibers from the anterior lobe of the cerebellum and sends output via the superior cerebellar peduncle to the red nucleus.

    • This question is part of the following fields:

      • Neuro-anatomy
      14.6
      Seconds

  • Question 6 - The cerebellum consist of which three lobes? ...

    Incorrect

    • The cerebellum consist of which three lobes?

      Your Answer: Anterior, posterior and inferior

      Correct Answer: Anterior, posterior and flocculonodular

      Explanation:

      The cerebellum consists of 3 lobes; Anterior, Posterior and Flocculonodular lobe.

    • This question is part of the following fields:

      • Neuro-anatomy
      6.5
      Seconds

  • Question 7 - Sequence of events in formation of speech are: ...

    Correct

    • Sequence of events in formation of speech are:

      Your Answer: Wernicke’s area---arcuate fasciculus---broca’s area---insula---motor cortex---speech

      Explanation:

      Wernicke’s area is located in the categorical hemisphere or left hemisphere in about 95% of right handed individuals and 60% of left handed individuals. It is involved in the comprehension or understanding of written and spoken language. In contrast Broca’s area is involved in production of language. Firstly, the language is accessed in the Wernicke’s area and these words are sent via the arcuate fasciculus to the Broca’s area, where instructions for articulation is generated. This is then sent from Broca’s are to the motor cortex for the articulation.

    • This question is part of the following fields:

      • Neuro-anatomy
      6.4
      Seconds

  • Question 8 - The thalamic main input from the cortex is via which tracts? ...

    Incorrect

    • The thalamic main input from the cortex is via which tracts?

      Your Answer: Corticostriatal tracts

      Correct Answer: Thalamocortical pathway

      Explanation:

      The thalamus is connected to cerebral cortex via the thalamocortical radiation.

    • This question is part of the following fields:

      • Neuro-anatomy
      12.7
      Seconds

  • Question 9 - In anterograde transport, dynein proteins transmit polypeptides/proteins in which format? ...

    Correct

    • In anterograde transport, dynein proteins transmit polypeptides/proteins in which format?

      Your Answer: In both of the above pathways

      Explanation:

      The majority of axonal proteins are synthesised in the cell body and transported along the axons. Microtubules run along the length of the axon and provide tracks for transportation. Kinesin and Dynein are motor proteins that transport proteins and other organelles. Kinesin moves forward or anterograde transport from cell body to axon, whereas Dynein moves retrograde from axon to cell body.

    • This question is part of the following fields:

      • Neuro-anatomy
      6.2
      Seconds

  • Question 10 - Which one of the following nerve fibers is involved in proprioception? ...

    Incorrect

    • Which one of the following nerve fibers is involved in proprioception?

      Your Answer: A β fiber

      Correct Answer: An α fiber

      Explanation:

      Proprioception, also known as kinaesthesia, is the sense through which humans perceive their own position and movements. α nerve fibers are specifically involved in transmitting proprioception stimuli.

    • This question is part of the following fields:

      • Neuro-anatomy
      3.7
      Seconds

  • Question 11 - On which presynaptic receptor does noradrenalin act to inhibit noradrenalin secretion? ...

    Incorrect

    • On which presynaptic receptor does noradrenalin act to inhibit noradrenalin secretion?

      Your Answer: Β1 receptor

      Correct Answer: Α2 receptor

      Explanation:

      Adregenic receptors are A1, A2, B1, B2, B3. Out of these, the function of the A2 receptor is inhibition of transmitter release including nor adrenalin and acetylcholine of the autonomic nervous system.

    • This question is part of the following fields:

      • Neuro-anatomy
      5.8
      Seconds

  • Question 12 - Which of the following is not innervated by the parasympathetic nerve supply? ...

    Incorrect

    • Which of the following is not innervated by the parasympathetic nerve supply?

      Your Answer: Salivary gland

      Correct Answer: Radial muscle of iris

      Explanation:

      The sphincter pupillae is supplied by the parasympathetic fibers from the Edinger Westphal nucleus of the oculomotor nerve. The dilator pupillae (radial muscle) is supplied by the postganglionic fibers of the superior cervical sympathetic ganglion. The parasympathetic nerve supply to the salivary glands originate in the parasympathetic nucleus of the facial nerve (superior salivatory nucleus) and the glossopharyngeal nerve (inferior salivatory nucleus). The parasympathetic preganglionic fibers originate in the dorsal nucleus of the vagus nerve and descend into the thorax in the vagus nerve. The fibers terminate by synapsing with postganglionic neurons in the cardiac plexuses. Postganglionic fibers terminate on the sinoatrial and atrioventricular nodes and on the coronary arteries Parasympathetic supply to the stomach is via the vagus nerve.

    • This question is part of the following fields:

      • Neuro-anatomy
      15.6
      Seconds

  • Question 13 - Choose the correct answer: The cerebrocerebellum… ...

    Incorrect

    • Choose the correct answer: The cerebrocerebellum…

      Your Answer:

      Correct Answer: All options are correct

      Explanation:

      Cerebrocerebellum is comprised of two lateral regions, the cerebellar hemispheres and communicates with the cerebral cortex. It is principally responsible for controlling coordination of movement. Three fiber bundles carry the input and output of the cerebellum. There are three cerebellar peduncles with different connections and functions. The three are mainly, superior, middle and inferior. The superior cerebellar peduncle is also known as the “Brachium conjunctivum”. It predominantly contains efferent fibers from the cerebellar nuclei, as well as some afferents from the spinocerebellar tract. The efferent pathways include cerebellorubral, dentatothalamic, and fastigioreticular fibers. These are tracts projecting from the deep cerebellar nuclei to the thalamus and red nucleus. The middle cerebellar peduncle connects to the pontine nucleus and the dorsal spinocerebellar tracts run through the superior cerebellar peduncle

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds

  • Question 14 - Which enzyme is responsible for the removal of acetylcholine from the synapse? ...

    Incorrect

    • Which enzyme is responsible for the removal of acetylcholine from the synapse?

      Your Answer:

      Correct Answer: Acetylcholinesterase

      Explanation:

      Acetylcholinesterase is the enzyme that is responsible for breaking down acetylcholine into choline and acetate. Both of these molecules are transported back to the presynaptic neuron to be synthesized again. This enzyme is attached to the collagen fibers of the basement membrane in the synaptic cleft.

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds

  • Question 15 - The axons of which neurons serve as the only output from the cerebellar...

    Incorrect

    • The axons of which neurons serve as the only output from the cerebellar cortex?

      Your Answer:

      Correct Answer: Purkinje

      Explanation:

      The cerebellar cortex consist of 3 layers. The molecular layer, the granule cell layer and the Purkinje cell layer in the middle. The Purkinje cells project into the deep cerebellar nuclei. They are the only output cells of the cerebellar cortex.

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds

  • Question 16 - Functions of the glossopharyngeal nerve include the following except: ...

    Incorrect

    • Functions of the glossopharyngeal nerve include the following except:

      Your Answer:

      Correct Answer: Proprioceptive input from muscles of the tongue and larynx

      Explanation:

      The glossopharyngeal nerve is a mixed nerve consisting of both sensory and motor fibers. It has several branches and five distinct general functions:
      Branchial motor- Special visceral efferent- supplies the Stylopharyngeus muscle and superior constrictor muscle.
      Visceral motor- general visceral efferent- provides parasympathetic innervation of the parotid gland.
      Visceral sensory- general visceral afferent- carries visceral sensory information from the carotid sinus and carotid body.
      General sensory- general somatic afferent- provides general sensory information from the inner surface of the tympanic membrane, upper pharynx and posterior one third of the tongue.
      Visceral afferent- special visceral afferent- provides taste sensation from the posterior one third of the tongue including the circumvallate papillae.

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds

  • Question 17 - The small opening in the cochlea through which the upper scala vestibuli and...

    Incorrect

    • The small opening in the cochlea through which the upper scala vestibuli and lower scala tympani communicates is called the:

      Your Answer:

      Correct Answer: Helicotrema

      Explanation:

      The helicotrema is the part of cochlear labyrinth where the scala tympani and the scala vestibuli meet.

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds

  • Question 18 - Regarding the innervation of the cerebral blood vessels, postganglionic sympathetic neurons have their...

    Incorrect

    • Regarding the innervation of the cerebral blood vessels, postganglionic sympathetic neurons have their cell bodies in the:

      Your Answer:

      Correct Answer: Superior cervical ganglia

      Explanation:

      The superior cervical ganglion (SCG) is a part of autonomic system which plays a major role in maintaining homeostasis of the body. This ganglion innervates structures in the head and neck and is the largest and the most superiorly located ganglion. The SCG provides sympathetic innervation to structures within the head, including the pineal gland, the blood vessels in the cranial muscles and the brain, the choroid plexus, the eyes, the lacrimal glands, the carotid body, the salivary glands, and the thyroid gland. The postganglionic axons of the SCG innervate the internal carotid artery and form the internal carotid plexus. The internal carotid plexus carries the postganglionic axons of the SCG to the eye, lacrimal gland, mucous membranes of the mouth, nose, and pharynx, and numerous blood-vessels in the head.

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds

  • Question 19 - The axons of the POST ganglionic neurons are mostly? ...

    Incorrect

    • The axons of the POST ganglionic neurons are mostly?

      Your Answer:

      Correct Answer: C fibers

      Explanation:

      According to Erlanger- Grasser classification preganglionic fibers are B fibers whereas post ganglionic fibers are C fibers.

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds

  • Question 20 - Which receptor type is associated with uterine contracture in pregnancy? ...

    Incorrect

    • Which receptor type is associated with uterine contracture in pregnancy?

      Your Answer:

      Correct Answer: Α1

      Explanation:

      Alpha-1 adrenergic receptors cause uterine contraction during pregnancy. They are linked to Gq-proteins that activate smooth muscle contraction through the IP3 signal transduction pathway.

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds

  • Question 21 - Glucose transport in the brain is mediated by: ...

    Incorrect

    • Glucose transport in the brain is mediated by:

      Your Answer:

      Correct Answer: GLUT 1

      Explanation:

      The facilitative glucose transporter mediates the transport of glucose from blood into neurons and glia in the brain. The primary isoforms in the brain are GLUT1 detected at high concentrations.

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds

  • Question 22 - Choose the correct answer: fibers in the superior cerebellar peduncle: ...

    Incorrect

    • Choose the correct answer: fibers in the superior cerebellar peduncle:

      Your Answer:

      Correct Answer: Are mainly ventral spinocerebellar tracts from the cerebellar nuclei to the thalamus and red nucleus

      Explanation:

      There are three cerebellar peduncles with different connections and functions. The three are mainly, superior, middle and inferior. The superior cerebellar peduncle is also known as the “Brachium conjunctivum”. It predominantly contains efferent fibers from the cerebellar nuclei, as well as some afferents from the spinocerebellar tract. The efferent pathways include cerebellorubral, dentatothalamic, and fastigioreticular fibers. These are tracts projecting from the deep cerebellar nuclei to the thalamus and red nucleus. The middle cerebellar peduncle connects to the pontine nucleus and the dorsal spinocerebellar tracts run through the superior cerebellar peduncle.

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds

  • Question 23 - Which one of the following neurotransmitters is considered a monoamine? ...

    Incorrect

    • Which one of the following neurotransmitters is considered a monoamine?

      Your Answer:

      Correct Answer: Acetylcholine

      Explanation:

      Acetylcholine is a major neurotransmitter in the peripheral nervous system. Monoamine neurotransmitters contain only one amino group joined to an aromatic ring. Acetylcholine is produced from acetyl-CoA and choline.

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds

  • Question 24 - Which of the following do not pass through the cavernous sinus? ...

    Incorrect

    • Which of the following do not pass through the cavernous sinus?

      Your Answer:

      Correct Answer: CN 2

      Explanation:

      Oculomotor nerve (N3), trochlear nerve (N4), ophthalmic and mandibular divisions of the trigeminal nerve (N5) pass along its lateral border. The abducent nerve (N6) passes through it along with the internal carotid artery.

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds

  • Question 25 - Which of the following is a form of synaptic plasticity? ...

    Incorrect

    • Which of the following is a form of synaptic plasticity?

      Your Answer:

      Correct Answer: Working memory

      Explanation:

      Synaptic plasticity is an important neurochemical foundation of working memory and generation of memory. Synaptic plasticity is the ability of synapses to strengthen or weaken over time in response to increases or decreases in their activity.

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds

  • Question 26 - What happens first during depolarisation of the membrane potential? ...

    Incorrect

    • What happens first during depolarisation of the membrane potential?

      Your Answer:

      Correct Answer: Gated Na channels open allowing the influx of Na

      Explanation:

      Generation of an action potential in response to a stimulus is a result of a previously maintained resting membrane potential (RMP). Generation of resting membrane potential is mediated mainly by potassium ions. Several membrane proteins maintain RMP by transport of ions in and out of cell. Na+/K+ ATPase pump maintains a concentration gradient of Na+ and K+ ions. Na+ concentration in extracellular fluid is higher compared to intracellular fluid and K+ ion concentration is higher intracellularly. Generation of an action potential facilitates opening of Na+ ion channels which allow for Na+ to diffuse inside the cell according to the concentration gradient.

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds

  • Question 27 - Which of the following are exclusively innervated by parasympathetic nerves? ...

    Incorrect

    • Which of the following are exclusively innervated by parasympathetic nerves?

      Your Answer:

      Correct Answer: Circular muscle of iris

      Explanation:

      Circular muscle of iris is exclusively supplied by the parasympathetic nerves.

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds

  • Question 28 - The motor speech area (Brocas Area) is: ...

    Incorrect

    • The motor speech area (Brocas Area) is:

      Your Answer:

      Correct Answer: Brodmann area 44

      Explanation:

      A Brodmann area in the brain is defined by cytoarchitecture, histology and organization of cells:
      Primary Sensory 3,1,2
      Primary Motor 4
      Premotor 6
      Primary Visual 17
      Primary Auditory 41
      Brocas 44

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds

  • Question 29 - Which receptor type is associated with bronchial muscle relaxation? ...

    Incorrect

    • Which receptor type is associated with bronchial muscle relaxation?

      Your Answer:

      Correct Answer: β2

      Explanation:

      β2-adrenoceptors are widely distributed in the respiratory tract. When they are activated, an intracellular response induces the activation of cyclic AMP; this, in turn, produces airway relaxation through phosphorylation of muscle regulatory proteins and modification of cellular Ca2+concentrations.

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds

  • Question 30 - Where are the cell bodies of preganglionic neurons located? ...

    Incorrect

    • Where are the cell bodies of preganglionic neurons located?

      Your Answer:

      Correct Answer: Lateral column

      Explanation:

      The cell bodies of the preganglionic neurons are located in the lateral grey column of the spinal cord and in the motor nuclei of the 3rd, 7th, 9th and 10th cranial nerves.

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds

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