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  • Question 1 - What is the average healing time for a femoral shaft fracture under normal...

    Correct

    • What is the average healing time for a femoral shaft fracture under normal circumstances? Choose ONE answer.

      Your Answer: 12 weeks

      Explanation:

      The process of fracture healing occurs naturally after traumatic bone disruption and begins with haemorrhage, then progresses through Inflammatory, reparative, and remodelling stages

      Average healing times of common fractures are:
      Femoral shaft: 12 weeks
      Tibia: 10 weeks
      Phalanges: 3 weeks
      Metacarpals: 4-6 weeks
      Distal radius: 4-6 weeks
      Humerus: 6-8 weeks

    • This question is part of the following fields:

      • General Pathology
      • Pathology
      10.9
      Seconds
  • Question 2 - Urine flow rate = 2 ml/min
    Urine concentration of creatinine = 18 mg/ml
    Plasma...

    Incorrect

    • Urine flow rate = 2 ml/min
      Urine concentration of creatinine = 18 mg/ml
      Plasma concentration of creatinine = 0.25 mg/ml

      What is the estimated glomerular filtration rate (eGFR)?

      Your Answer: 2.5 ml/min

      Correct Answer: 144 ml/min

      Explanation:

      GFR can be estimated by:
      GFR = UCr x V / PCr
      Where:
      UCr = urine concentration of creatinine
      PCr = plasma concentration of creatinine
      V = rate of urine flow

      In this case GFR = (18 x 2) / 0.25 = 144 ml/min

      Note: Creatinine is used to estimate GFR because it is an organic base naturally produced by muscle breakdown, it is freely filtered at the glomerulus, it is not reabsorbed from the nephron, it is not produced by the kidney, it is not toxic, and it doesn’t alter GFR.

    • This question is part of the following fields:

      • Physiology
      • Renal Physiology
      12
      Seconds
  • Question 3 - A 53 year old women presents to the emergency room with a chronic...

    Incorrect

    • A 53 year old women presents to the emergency room with a chronic cough. The pulmonary receptors likely to be involved in causing her cough are:

      Your Answer: Juxtapulmonary (J) receptors

      Correct Answer: Irritant receptors

      Explanation:

      Throughout the airways, there are irritant receptors which are located between epithelial cells which are made of rapidly adapting afferent myelinated fibres in the vagus nerve. A cough is as a result of receptor stimulation located in the trachea, hyperpnoea is as a result of receptor stimulation in the lower airway. Stimulation may also result in reflex bronchial and laryngeal constriction. Many factors can stimulate irritant receptors. These include irritant gases, smoke and dust, airway deformation, pulmonary congestion, rapid inflation/deflation and inflammation. Deep augmented breaths or sighs seen every 5 – 20 minutes at rest are due to stimulation of these irritant receptors. This reverses the slow lung collapse that occurs in quiet breathing.

    • This question is part of the following fields:

      • Physiology
      • Respiratory
      15.8
      Seconds
  • Question 4 - Regarding myeloma, which of the following statements is CORRECT: ...

    Incorrect

    • Regarding myeloma, which of the following statements is CORRECT:

      Your Answer:

      Correct Answer: Myeloma is associated with marked rouleaux formation on blood film.

      Explanation:

      98% of cases of myeloma occur over the age of 40 years with a peak incidence between 65 and 70 years. The disease is twice as common in black individuals compared to those of white or Asian origin. Laboratory findings include presence of a paraprotein in serum/urine (the paraprotein is IgG in 60% of cases, IgA in 20% and light chain only in almost all the rest) and marked Rouleaux formation on blood film. There is no cure for myeloma. The overall median survival is now 7-10 years and in younger (less than 50 years) patients it can be over 10 years.

    • This question is part of the following fields:

      • Haematology
      • Pathology
      0
      Seconds
  • Question 5 - Which of the following clinical features is a feature of a chronic extravascular...

    Incorrect

    • Which of the following clinical features is a feature of a chronic extravascular haemolytic anaemia:

      Your Answer:

      Correct Answer: Gallstones

      Explanation:

      Clinical features of haemolytic anaemia include:
      Anaemia
      Jaundice (caused by unconjugated bilirubin in plasma, bilirubin is absent from urine)
      Pigment gallstones
      Splenomegaly
      Ankle ulcers
      Expansion of marrow with, in children, bone expansion e.g. frontal bossing in beta-thalassaemia major
      Aplastic crisis caused by parvovirus

    • This question is part of the following fields:

      • Haematology
      • Pathology
      0
      Seconds
  • Question 6 - What is the effect of activated vitamin D on the renal handling of...

    Incorrect

    • What is the effect of activated vitamin D on the renal handling of calcium:

      Your Answer:

      Correct Answer: Increases calcium reabsorption in the distal tubule

      Explanation:

      Activated vitamin D acts to:
      GUT:increase calcium and phosphate absorption in the small intestine (the main action)
      KIDNEYS:increase renal calcium reabsorption (in the distal tubule via activation of a basolateral Ca2+ATPase pump), increase renal phosphate reabsorption, inhibit 1-alpha-hydroxylase activity in the kidneys (negative feedback)
      PARATHYROID GLANDS:inhibit PTH secretion from the parathyroid glands

    • This question is part of the following fields:

      • Endocrine
      • Physiology
      0
      Seconds
  • Question 7 - A 25-year-old footballer develops pain and stiffness in his thigh. A diagnosis of...

    Incorrect

    • A 25-year-old footballer develops pain and stiffness in his thigh. A diagnosis of iliopsoas syndrome is made.
      Iliacus is innervated by which of the following nerves? Select ONE answer only.

      Your Answer:

      Correct Answer: Femoral nerve

      Explanation:

      Iliacus is innervated by the femoral nerve.

    • This question is part of the following fields:

      • Anatomy
      • Lower Limb
      0
      Seconds
  • Question 8 - A patient had a left Colles' fracture, which you were able to repair. It...

    Incorrect

    • A patient had a left Colles' fracture, which you were able to repair. It was their second fragility fracture this year, and you'd like to provide them some tips on how to keep their bones healthy.

      What percentage of the calcium in the body is kept in the bones? Only ONE response is acceptable.

      Your Answer:

      Correct Answer: 99%

      Explanation:

      Calcium is stored in bones for nearly all of the body’s calcium, but it is also found in some cells (most notably muscle cells) and the blood. The average adult diet comprises roughly 25 mmol of calcium per day, of which the body absorbs only about 5 mmol.

    • This question is part of the following fields:

      • Endocrine Physiology
      • Physiology
      0
      Seconds
  • Question 9 - A patient suffers a lower limb fracture that causes damage to the nerve...

    Incorrect

    • A patient suffers a lower limb fracture that causes damage to the nerve that innervates peroneus brevis.
      Peroneus brevis receives its innervation from which of the following nerves? Select ONE answer only.

      Your Answer:

      Correct Answer: Superficial peroneal nerve

      Explanation:

      Peroneus brevis is innervated by the superficial peroneal nerve.
      Peroneus longus is innervated by the superficial peroneal nerve.
      Peroneus tertius is innervated by the deep peroneal nerve.

    • This question is part of the following fields:

      • Anatomy
      • Lower Limb
      0
      Seconds
  • Question 10 - An 18-year-old student presents with a 1-week history of sore throat, low grade...

    Incorrect

    • An 18-year-old student presents with a 1-week history of sore throat, low grade fever, and malaise. Upon history taking, she noted that she had a fine rash over her body a week ago that quickly fades. Further examination and observation was done and the presence of mild splenomegaly was noted. Her test shows positive for heterophile antibody test, suspecting a diagnosis of infectious mononucleosis.

      Which of the following characteristics is mostly associated with the diagnosis of infectious mononucleosis?

      Your Answer:

      Correct Answer: Atypical lymphocytes

      Explanation:

      Epstein-Barr virus causes infectious mononucleosis which is a clinical entity characterized by sore throat, cervical lymph node enlargement, fatigue and fever.

      It is accompanied by atypical large peripheral blood lymphocytes. These atypical lymphocytes, also known as Downey cells, are actually activated CD8 T lymphocytes, most of which are responding to EBV-infected cells.

    • This question is part of the following fields:

      • Microbiology
      • Specific Pathogen Groups
      0
      Seconds
  • Question 11 - You've been summoned to a young man in the resus area who is...

    Incorrect

    • You've been summoned to a young man in the resus area who is experiencing an SVT. You decide to use adenosine after trying several vagal manoeuvres without success.

      Which of the following is the correct adenosine mechanism of action?

      Your Answer:

      Correct Answer: Opens K + channels in the heart

      Explanation:

      The purine nucleoside adenosine is used to diagnose and treat paroxysmal supraventricular tachycardia. Adenosine works by stimulating A1-adenosine receptors and opening potassium channels that are sensitive to acetylcholine. This causes the atrioventricular (AV) node’s cell membrane to become hyperpolarized, slowing conduction by inhibiting calcium channels.
      Patients who have had a heart transplant are extremely sensitive to the effects of adenosine and should start with a lower dose of 3 mg, then 6 mg, and finally 12 mg.

      Dipyridamole potentiates the effects of adenosine, so it should be used with caution in patients who are taking it.

      The use of adenosine is contraindicated in the following situations:
      Asthma
      COPD (chronic obstructive pulmonary disease)
      Decompensated heart failure 
      Long QT syndrome
      AV block in the second or third degree
      Sinusitis is a condition in which the sinuses become (unless pacemaker fitted)
      Hypotension that is severe

    • This question is part of the following fields:

      • Cardiovascular Pharmacology
      • Pharmacology
      0
      Seconds
  • Question 12 - A patient is sent in by her GP with suspected ectopic pregnancy. Tubal...

    Incorrect

    • A patient is sent in by her GP with suspected ectopic pregnancy. Tubal ectopic pregnancies occur most commonly in which part of the uterine tube:

      Your Answer:

      Correct Answer: Ampulla

      Explanation:

      Ectopic pregnancy most commonly occurs in the ampulla (70% of cases).

    • This question is part of the following fields:

      • Abdomen
      • Anatomy
      0
      Seconds
  • Question 13 - A young pregnant woman is in the late stages of her pregnancy. She...

    Incorrect

    • A young pregnant woman is in the late stages of her pregnancy. She is administered a drug that results in her newborn being born with respiratory depression. The baby also suffers from neonatal withdrawal syndrome.

      Out of the following, which drug is most likely responsible for the baby's condition?

      Your Answer:

      Correct Answer: Diazepam

      Explanation:

      Benzodiazepines are used as a first-line treatment in breaking seizures and in status epilepticus as they are rapid-acting.

      Use of benzodiazepines in the late third-trimester or exposure during labour is associated with great risks to the foetus/neonate. Babies can exhibit either floppy infant syndrome, or marked neonatal withdrawal symptoms. Symptoms vary from mild sedation, hypotonia, and reluctance to suck, to apnoeic spells, cyanosis, and impaired metabolic responses to cold stress. These symptoms have been reported to persist for periods from hours to months after birth.

      They also cross into breast milk and should be used with caution in breastfeeding mothers

    • This question is part of the following fields:

      • CNS Pharmacology
      • Pharmacology
      0
      Seconds
  • Question 14 - Regarding folate requirements, which of the following statements is CORRECT: ...

    Incorrect

    • Regarding folate requirements, which of the following statements is CORRECT:

      Your Answer:

      Correct Answer: Dietary folate is found particularly in leafy green vegetables and liver.

      Explanation:

      Megaloblastic anemia results from inhibition of DNA synthesis during red blood cell production. When DNA synthesis is impaired, the cell cycle cannot progress from the growth stage to the mitosis stage. This leads to continuing cell growth without division, which presents as macrocytosis, with an increase in mean corpuscular volume (MCV). The defect in red cell DNA synthesis is most often due to hypovitaminosis, specifically vitamin B12 deficiency or folate deficiency.
      Folate is an essential vitamin found in most foods, especially liver, green vegetables and yeast. The normal daily diet contains 200 – 250 μg, of which about 50% is absorbed. Daily adult requirements are about 100 μg. Absorption of folate is principally from the duodenum and jejunum. Stores of folate are normally only adequate for 4 months and so features of deficiency may be apparent after this time.

    • This question is part of the following fields:

      • Haematology
      • Pathology
      0
      Seconds
  • Question 15 - A 57-year-old male presents to the orthopaedic clinic complaining of pain and swelling...

    Incorrect

    • A 57-year-old male presents to the orthopaedic clinic complaining of pain and swelling in the left knee joint. On examination, the left knee is swollen, tender and erythematous. The patient is booked for joint aspiration, and a diagnosis of pseudogout is made following the aspiration.

      Which types of crystals would be seen in the joint aspirate to lead to this diagnosis?

      Your Answer:

      Correct Answer: Positively birefringent brick-shaped crystals

      Explanation:

      Gout and pseudogout are both characterised by crystal deposition in the affected joints. The deposition of urate crystals causes gout, while calcium pyrophosphate crystals cause pseudogout. The crystals can be distinguished microscopically because urate crystals are negatively birefringent needle-shaped crystals, whilst calcium pyrophosphate crystals are positively birefringent brick-shaped crystals.

    • This question is part of the following fields:

      • General Pathology
      • Pathology
      0
      Seconds
  • Question 16 - A blood culture was performed from a sample taken from a patient. It...

    Incorrect

    • A blood culture was performed from a sample taken from a patient. It was noted that a Gram-negative coccus organism was grown.

      Among the following microorganisms, which is considered an example of a Gram-negative coccus?

      Your Answer:

      Correct Answer: Neisseria menigitidis

      Explanation:

      Staphylococcus aureus = Gram-positive coccus
      Bacillus cereus = Gram-positive bacillus
      Campylobacter jejuni = Gram-negative bacillus
      Escherichia coli = Gram-negative bacillus

      In Gram staining, crystal violet is a purple stain that is used to stain the bacteria first. The stained bacteria are decolorized and then stained with a red stain, which is safranin. Bacteria with thick cell walls keep the purple stain and are called Gram-positive. Thin-walled bacteria are easily decolorized so when safranin, the red stain, is placed on the organisms, they become red or Gram-negative.
      Neisseria species appear as Gram-negative diplococci because they form pairs and their adjacent ends are flattened that is why they are also described to have a coffee-bean or kidney-bean shape.

    • This question is part of the following fields:

      • Microbiology
      • Principles Of Microbiology
      0
      Seconds
  • Question 17 - The lymph drainage of the anal canal above the pectinate line is initially...

    Incorrect

    • The lymph drainage of the anal canal above the pectinate line is initially to the:

      Your Answer:

      Correct Answer: Internal iliac nodes

      Explanation:

      Above the pectinate line, the anal canal drains to the internal iliac lymph nodes which subsequently drain to the lumbar (para-aortic) nodes.

    • This question is part of the following fields:

      • Abdomen
      • Anatomy
      0
      Seconds
  • Question 18 - A young 20-year-old boy is a known case of type I diabetes mellitus....

    Incorrect

    • A young 20-year-old boy is a known case of type I diabetes mellitus. Today, he presents with polyuria, polydipsia, and abdominal pain in the emergency department. His blood sugar is drawn, which is markedly elevated to 7 mmol/L. Quick ABGs are drawn, which show metabolic acidosis. You diagnose the patient to be suffering from diabetic ketoacidosis (DKA) and immediately commence its treatment protocol in which insulin is also administered.

      Out of the following, which parameter is MOST likely to change due to initiating insulin?

      Your Answer:

      Correct Answer: Potassium

      Explanation:

      Diabetes ketoacidosis is an acute complication of diabetes mellitus. Insulin is administered to achieve euglycemia, and crystalloids or colloidal solution is administered to achieve euvolemia and euelectrolytaemia.

      Potassium levels severely fluctuate during the treatment of DKA, hypokalaemia being more common. Insulin promotes the cell to take up potassium from the extracellular space via increased sodium-potassium pump activity.

      It is important to monitor potassium levels during the treatment of DKA regularly. It is widely suggested that the normal saline shall be used for initial resuscitation, and once the potassium level is retrieved, the patient can be started on potassium replacement should the serum potassium level be between 3.3 and 4.5 mmol/L
      If potassium levels fall below 3.3 mmol/l, insulin administration may need to be interrupted to correct the hypokalaemia.

    • This question is part of the following fields:

      • Endocrine Pharmacology
      • Pharmacology
      0
      Seconds
  • Question 19 - A 22-year-old presents with acute severe asthma. He takes a drug prescribed by...

    Incorrect

    • A 22-year-old presents with acute severe asthma. He takes a drug prescribed by her GP but cannot recall the name and is receiving regular salbutamol nebulisers. His current potassium level is 2.8 mmol/l.

      Which drug is least likely to have caused his hypokalaemia?

      Your Answer:

      Correct Answer: Spironolactone

      Explanation:

      Serious hypokalaemia can occur in severe asthma and the effect can be potentiated by concomitant treatment with theophyllines like aminophylline, corticosteroids, thiazide and loop diuretics, and hypoxia. Plasma-potassium concentration should be monitored in severe asthma.

      Spironolactone, a potassium-sparing diuretic, is not likely to have contributed to patients hypokalaemia.

    • This question is part of the following fields:

      • Pharmacology
      • Respiratory Pharmacology
      0
      Seconds
  • Question 20 - Which of the following describes the site of a Meckel's diverticulum: ...

    Incorrect

    • Which of the following describes the site of a Meckel's diverticulum:

      Your Answer:

      Correct Answer: Ileum

      Explanation:

      Meckel’s lies on the antimesenteric surface of the middle-to-distal ileum, approximately 2 feet proximal to the ileocaecal junction. It appears as a blind-ended tubular outpouching of bowel, about 2 inches long, occurring in about 2% of the population, and may contain two types of ectopic tissue (gastric and pancreatic). The rich blood supply to the diverticulum is provided by the superior mesenteric artery.Proximal to the major duodenal papilla the duodenum is supplied by the gastroduodenal artery (branch of the coeliac trunk) and distal to the major duodenal papilla it is supplied by the inferior pancreaticoduodenal artery (branch of superior mesenteric artery). The arterial supply to the jejunoileum is from the superior mesenteric artery.

    • This question is part of the following fields:

      • Abdomen
      • Anatomy
      0
      Seconds
  • Question 21 - A 64-year-old man presents with an acute episode of gout. He has a...

    Incorrect

    • A 64-year-old man presents with an acute episode of gout. He has a history of chronic heart failure and hypertension. His current medications include ramipril and furosemide.
      Which of the following statements regarding the treatment of gout is true? Select ONE answer only.

      Your Answer:

      Correct Answer: Colchicine has a role in prophylactic treatment

      Explanation:

      In the absence of any contra-indications, high-dose NSAIDs are the first-line treatment for acute gout. Naproxen 750 mg as a stat dose followed by 250 mg TDS is a commonly used and effective regime.
      Aspirin should not be used in gout as it reduces the urinary clearance of urate and interferes with the action of uricosuric agents. Naproxen, Diclofenac or Indomethacin are more appropriate choices.
      Allopurinol is used prophylactically, preventing future attacks by reducing serum uric acid levels. It should not be started in the acute phase as it increases the severity and duration of symptoms.
      Colchicine acts on the neutrophils, binding to tubulin to prevent neutrophil migration into the joint. It is as effective as NSAIDs in relieving acute attacks. It also has a role in prophylactic treatment if Allopurinol is not tolerated.
      NSAIDs are contra-indicated in heart failure as they can cause fluid retention and congestive cardiac failure. Colchicine is the preferred treatment in patients with heart failure or those who are intolerant of NSAIDs.

    • This question is part of the following fields:

      • Musculoskeletal Pharmacology
      • Pharmacology
      0
      Seconds
  • Question 22 - Regarding loop diuretics, which of the following statements is INCORRECT: ...

    Incorrect

    • Regarding loop diuretics, which of the following statements is INCORRECT:

      Your Answer:

      Correct Answer: The risk of hypokalaemia is greater with loop diuretics than with an equipotent dose of a thiazide diuretic.

      Explanation:

      Hypokalaemia can occur with both thiazide and loop diuretics. The risk of hypokalaemia depends on the duration of action as well as the potency and is thus greater with thiazides than with an equipotent dose of a loop diuretic. Hypokalaemia is dangerous in severe cardiovascular disease and in patients also being treated with cardiac glycosides. Often the use of potassium-sparing diuretics avoids the need to take potassium supplements. In hepatic failure, hypokalaemia caused by diuretics can precipitate encephalopathy, particularly in alcoholic cirrhosis.

    • This question is part of the following fields:

      • Cardiovascular
      • Pharmacology
      0
      Seconds
  • Question 23 - Regarding postural hypotension, which of the following statements is INCORRECT: ...

    Incorrect

    • Regarding postural hypotension, which of the following statements is INCORRECT:

      Your Answer:

      Correct Answer: Postural hypotension usually causes a reflex bradycardia.

      Explanation:

      On standing from a prone position, gravity causes blood to pool in veins in the legs. Central venous pressure (CVP) falls, causing a fall in stroke volume and cardiac output (due to Starling’s law) and thus a fall in blood pressure. Normally this fall in BP is rapidly corrected by the baroreceptor reflex which causes venoconstriction (partially restoring CVP), and an increase in heart rate and contractility, so restoring cardiac output and blood pressure. Impaired autonomic nervous activity in the elderly accounts for the greater likelihood of postural hypotension. Any symptoms of dizziness, blurred vision or syncope is due to a transient fall in cerebral perfusion that occurs before cardiac output and mean arterial pressure (MAP) can be corrected.

    • This question is part of the following fields:

      • Cardiovascular
      • Physiology
      0
      Seconds
  • Question 24 - Through which of the following anatomical structures does an indirect inguinal hernia pass?...

    Incorrect

    • Through which of the following anatomical structures does an indirect inguinal hernia pass?

      Your Answer:

      Correct Answer: External oblique

      Explanation:

      Inguinal hernias are subdivided into direct and indirect.

      An indirect hernia occurs when abdominal contents protrude through the internal inguinal ring and into the inguinal canal. This occurs lateral to the inferior epigastric vessels. The hernia contents may extend into the scrotum.

      A direct inguinal hernia is protrusion of abdominal contents through the transversalis fascia within Hesselbach’s triangle. The borders of Hesselbach’s triangle are the inferior epigastric vessels superolaterally, the rectus sheath medially, and inguinal ligament inferiorly.

      The deep (internal) inguinal ring is located above and halfway between the pubic tubercle and the anterior superior iliac spine. This serves as the entrance to the inguinal canal. The superficial (external) inguinal ring lies immediately above and medial to the pubic tubercle. This triangular opening is a defect in the external oblique aponeurosis, and forms the exit of the inguinal canal.

    • This question is part of the following fields:

      • Abdomen And Pelvis
      • Anatomy
      0
      Seconds
  • Question 25 - Which of the following is the most common cause of megaloblastic anaemia: ...

    Incorrect

    • Which of the following is the most common cause of megaloblastic anaemia:

      Your Answer:

      Correct Answer: Vitamin B12 deficiency

      Explanation:

      Megaloblastic anemia results from inhibition of DNA synthesis during red blood cell production. When DNA synthesis is impaired, the cell cycle cannot progress from the growth stage to the mitosis stage. This leads to continuing cell growth without division, which presents as macrocytosis, with an increase in mean corpuscular volume (MCV). The defect in red cell DNA synthesis is most often due to hypovitaminosis, specifically vitamin B12 deficiency or folate deficiency.
      Folate is an essential vitamin found in most foods, especially liver, green vegetables and yeast. The normal daily diet contains 200 – 250 μg, of which about 50% is absorbed. Daily adult requirements are about 100 μg. Absorption of folate is principally from the duodenum and jejunum. Stores of folate are normally only adequate for 4 months and so features of deficiency may be apparent after this time.

    • This question is part of the following fields:

      • Haematology
      • Pathology
      0
      Seconds
  • Question 26 - A 37-year-old man presents with breathlessness on exertion and dry cough, fever for...

    Incorrect

    • A 37-year-old man presents with breathlessness on exertion and dry cough, fever for the past 2 days and bilateral pleuritic chest pain.

      He had been diagnosed with HIV and commenced on HAART but due to side effects, his compliance has been poor over the last few months.

      On examination you note scattered crackles and wheeze bilaterally, cervical and inguinal lymphadenopathy, and oral thrush. At rest his oxygen saturation is 97% but this drops to 87% on walking. There is perihilar fluffy shadowing seen on his chest X-ray.

      Which of these organisms is the most likely causative organism?

      Your Answer:

      Correct Answer: Pneumocystis jirovecii

      Explanation:

      All of the organisms listed above can cause pneumonia in immunocompromised individuals but the most likely cause in this patient is Pneumocystis jirovecii.

      It is a leading AIDS-defining infection in HIV-infected individuals and causes opportunistic infection in immunocompromised individuals. HIV patients with a CD4 count less than 200 cells/mm3 are more prone.

      The clinical features of pneumonia caused by Pneumocystis jirovecii are:
      Fever, chest pain, cough (usually non-productive), exertional dyspnoea, tachypnoea, crackles and wheeze.
      Desaturation on exertion is a very sensitive sign of Pneumocystis jirovecii pneumonia.

      Chest X-ray can show perihilar fluffy shadowing (as is seen in this case) but can also be normal.

    • This question is part of the following fields:

      • Microbiology
      • Specific Pathogen Groups
      0
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  • Question 27 - Which of the following is an example of a non-parametric test: ...

    Incorrect

    • Which of the following is an example of a non-parametric test:

      Your Answer:

      Correct Answer: All of the above

      Explanation:

      All of the above answers are non-parametric tests.

    • This question is part of the following fields:

      • Evidence Based Medicine
      • Statistics
      0
      Seconds
  • Question 28 - Which of the following statements is true regarding the extensor pollicis longus? ...

    Incorrect

    • Which of the following statements is true regarding the extensor pollicis longus?

      Your Answer:

      Correct Answer: It is innervated by the posterior interosseous nerve

      Explanation:

      Extensor pollicis longus is part of the deep extensors of the forearm together with extensor pollicis brevis, abductor pollicis longus, extensor indicis and supinator muscles. It is located on the posterior aspect of forearm, extending from the middle third of the ulna, and adjacent interosseous membrane, to the distal phalanx of the thumb.

      Extensor digitorum is innervated by posterior interosseous nerve which is a continuation of a deep branch of radial nerve (root value C7 and C8).

      Extensor pollicis brevis receives its blood supply from the posterior interosseous artery and perforating branches of the anterior interosseous artery.

      The main action of extensor pollicis longus is extension of the thumb at the metacarpophalangeal and interphalangeal joints. Extension at the metacarpophalangeal joint occurs in synergy with extensor pollicis brevis muscle. When the thumb reaches the full extension or abduction, extensor pollicis longus can also assist in adduction of the thumb.

    • This question is part of the following fields:

      • Anatomy
      • Upper Limb
      0
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  • Question 29 - Regarding cellular respiration, which of the following statements is CORRECT: ...

    Incorrect

    • Regarding cellular respiration, which of the following statements is CORRECT:

      Your Answer:

      Correct Answer: When fats are used as the primary energy source, an excess of acetyl-CoA is produced.

      Explanation:

      Cellular respiration is the process by which cells obtain energy in the form of adenosine triphosphate (ATP). ATP transfers chemical energy from the energy rich substances in the cell to the cell’s energy requiring reactions e.g. active transport, DNA replication and muscle contraction.Cellular respiration is essentially a three step process: 1) Glycolysis, 2)The Krebs cycle, 3)The electron transfer system.The main respiratory substrate used by cells is 6-carbon glucose. Fats and proteins can also be used as respiratory substrates. When fats are being used as the primary energy source, in the absence of glucose, an excess amount of acetyl-CoA is produced, and is converted into acetone and ketone bodies. This can occur in starvation, fasting or in diabetic ketoacidosis. Proteins are used as an energy source only if protein intake is very high, or if glucose and fat sources are depleted.

    • This question is part of the following fields:

      • Basic Cellular
      • Physiology
      0
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  • Question 30 - A 17-year-old male patient diagnosed with cystic fibrosis is experiencing shortness of breath,...

    Incorrect

    • A 17-year-old male patient diagnosed with cystic fibrosis is experiencing shortness of breath, coughing, and flu-like symptoms. His X-ray results shows atelectasis, or collapsed lung, specifically in his lower right lung. All of the following statements are true regarding collapsed lungs, except for which one.

      Your Answer:

      Correct Answer: Atelectasis is an example of a perfusion defect

      Explanation:

      Atelectasis is a complete or partial collapse of the lung. It occurs when the alveoli deflate or are filled with alveolar fluid. It is considered a ventilation defect of the alveoli due to cystic fibrosis. It is not a perfusion defect. A perfusion defect will produce pathological dead space in which the lung alveoli are ventilated adequately but are not perfused, and there is no gas exchange. While with atelectasis, the alveoli remain perfused. However, there is impaired oxygen delivery and intrapulmonary shunting of blood will be present in the collapsed area. Since there is no exchange of gas at the capillary-alveolar interface of the collapsed segments, the pulmonary capillary blood will have similar PO2 and PCO2.

    • This question is part of the following fields:

      • Physiology
      • Respiratory Physiology
      0
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

General Pathology (1/1) 100%
Pathology (1/2) 50%
Physiology (1/1) 100%
Respiratory (1/1) 100%
Haematology (0/1) 0%
Passmed