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  • Question 1 - In the olfactory pathway: Mitral cells project to five regions of the olfactory...

    Incorrect

    • In the olfactory pathway: Mitral cells project to five regions of the olfactory cortex. Which one of the following is not one of the five regions?

      Your Answer: Piriform cortex

      Correct Answer: Posterior olfactory nucleus

      Explanation:

      The olfactory system contains peripheral and central divisions which are connected by transduction structures. Peripheral division consists mainly of the nostrils, ethmoid bone, nasal cavity, and the olfactory epithelium. Olfactory neurons are receptor cells in the epithelium that detect odour molecules dissolved in the mucus and transmit information about the odour to the brain in a process called sensory transduction. Olfactory nerves and fibers transmit information about odours from the peripheral olfactory system to the central olfactory system of the brain. The main olfactory bulb transmits pulses to both mitral and tufted cells, which help determine odour concentration. These cells also note differences between highly similar odours and use that data to aid in later recognition. The cells are different with the mitral having low firing-rates and being easily inhibited by neighbouring cells, while tufted have high rates of firing and are more difficult to inhibit. The uncus houses the olfactory cortex which includes the piriform cortex, amygdala, olfactory tubercle, and para-hippocampal gyrus. Entorhinal cortex is an area of middle temporal lobe that has connection with the para-hippocampal gyrus.

    • This question is part of the following fields:

      • Neuro-anatomy
      32.8
      Seconds
  • Question 2 - The superior orbital fissure is the site of entry/exit for which of the...

    Incorrect

    • The superior orbital fissure is the site of entry/exit for which of the following group of nerves?

      Your Answer: CN III, IV, V2, VI

      Correct Answer: CN III, IV, V1, VI

      Explanation:

      The superior and inferior divisions of oculomotor nerve (III), trochlear nerve (IV), lacrimal, frontal and nasociliary branches of ophthalmic V1 and the abducens nerve (VI)

    • This question is part of the following fields:

      • Neuro-anatomy
      17.2
      Seconds
  • Question 3 - In a 60kg adult male with normal mean arterial pressure and oxygen consumption,...

    Incorrect

    • In a 60kg adult male with normal mean arterial pressure and oxygen consumption, what proportion of the cardiac output at rest goes to the brain?

      Your Answer: 20-25%

      Correct Answer: 10-15%

      Explanation:

      The rate of cerebral blood flow in the adult is typically 750 millilitres per minute, which is 10-15% of the cardiac output. On average around 13.9% of cardiac output is distributed to the brain.

    • This question is part of the following fields:

      • Neuro-anatomy
      82.6
      Seconds
  • Question 4 - The thalamic main input from the cortex is via which tracts? ...

    Incorrect

    • The thalamic main input from the cortex is via which tracts?

      Your Answer: Corticostriatal tracts

      Correct Answer: Thalamocortical pathway

      Explanation:

      The thalamus is connected to cerebral cortex via the thalamocortical radiation.

    • This question is part of the following fields:

      • Neuro-anatomy
      37.3
      Seconds
  • Question 5 - Which of the following associations is false? ...

    Correct

    • Which of the following associations is false?

      Your Answer: Mandibular nerve – foramen lacerum

      Explanation:

      – The olfactory nerves pass through the cribriform plate
      – The maxillary division of the trigeminal nerve passes through the foramen rotundum
      – The facial nerve passes through the stylomastoid foramen
      – The mandibular division of the trigeminal nerve pass through the foramen ovale
      – The glossopharyngeal nerve passes through the jugular foramen.

    • This question is part of the following fields:

      • Neuro-anatomy
      17.1
      Seconds
  • Question 6 - The pathway responsible for the discriminative aspect of pain, is called the: ...

    Incorrect

    • The pathway responsible for the discriminative aspect of pain, is called the:

      Your Answer: Spinothalamic tractus

      Correct Answer: Neospinothalamic tract

      Explanation:

      The spinothalamic tract is an ascending or a sensory tract, responsible for transmission of pain and temperature. The neospinothalamic tract is responsible for fast pain or discriminative pain whereas the palaeospinothalamic tract is responsible for transmission of slow pain.

    • This question is part of the following fields:

      • Neuro-anatomy
      30.7
      Seconds
  • Question 7 - Where are the cell bodies of preganglionic neurons located? ...

    Incorrect

    • Where are the cell bodies of preganglionic neurons located?

      Your Answer: Dorsal root

      Correct Answer: Lateral column

      Explanation:

      The cell bodies of the preganglionic neurons are located in the lateral grey column of the spinal cord and in the motor nuclei of the 3rd, 7th, 9th and 10th cranial nerves.

    • This question is part of the following fields:

      • Neuro-anatomy
      11.1
      Seconds
  • Question 8 - In the basal ganglia, the Lentiform nucleus is formed by which two nuclei?...

    Incorrect

    • In the basal ganglia, the Lentiform nucleus is formed by which two nuclei?

      Your Answer: Caudate and putamen

      Correct Answer: Putamen and Globus pallidus

      Explanation:

      The Basal Ganglia are composed of the following structures: Caudate, putamen, Globus pallidus, subthalamic nucleus and substantia nigra. The lentiform nucleus comprises of the putamen and the Globus pallidus.

    • This question is part of the following fields:

      • Neuro-anatomy
      33.6
      Seconds
  • Question 9 - The consensual light reflex is co-ordinated mainly in the: ...

    Incorrect

    • The consensual light reflex is co-ordinated mainly in the:

      Your Answer: Lateral geniculate geniculate nucleus

      Correct Answer: Edinger-Westphal nucleus

      Explanation:

      The consensual light reflex occurs when an individual’s right eye is shielded and light shines into the left eye, constriction of the right pupil will occur, as well as the left. This is because the afferent signal sent through one optic nerve connects to the Edinger-Westphal nucleus, whose axons run to both the right and the left oculomotor nerves.

    • This question is part of the following fields:

      • Neuro-anatomy
      36.5
      Seconds
  • Question 10 - The Afferent neuron that supplies all sensory elements of the muscle spindle is...

    Incorrect

    • The Afferent neuron that supplies all sensory elements of the muscle spindle is what type of sensory neuron?

      Your Answer: IIb

      Correct Answer: Ia

      Explanation:

      Muscle spindle is supplied by both sensory and motor nerves. Sensory supply is Type Ia fibers whereas motor supply is gamma motor neurone.

    • This question is part of the following fields:

      • Neuro-anatomy
      23.1
      Seconds
  • Question 11 - The small opening in the cochlea through which the upper scala vestibuli and...

    Incorrect

    • The small opening in the cochlea through which the upper scala vestibuli and lower scala tympani communicates is called the:

      Your Answer: Round window

      Correct Answer: Helicotrema

      Explanation:

      The helicotrema is the part of cochlear labyrinth where the scala tympani and the scala vestibuli meet.

    • This question is part of the following fields:

      • Neuro-anatomy
      9.6
      Seconds
  • Question 12 - The tectum as part of the Midbrain contains which structure important in visual...

    Incorrect

    • The tectum as part of the Midbrain contains which structure important in visual reflexes.

      Your Answer: Substantia nigra

      Correct Answer: Superior colliculus

      Explanation:

      The tectum is a part of the midbrain, specifically, the dorsal part of the midbrain. The tectum consists of the superior and inferior colliculi. The superior colliculus is involved in preliminary visual processing and control of eye movement.

    • This question is part of the following fields:

      • Neuro-anatomy
      17.5
      Seconds
  • Question 13 - The axons of which neurons serve as the only output from the cerebellar...

    Incorrect

    • The axons of which neurons serve as the only output from the cerebellar cortex?

      Your Answer: Basket

      Correct Answer: Purkinje

      Explanation:

      The cerebellar cortex consist of 3 layers. The molecular layer, the granule cell layer and the Purkinje cell layer in the middle. The Purkinje cells project into the deep cerebellar nuclei. They are the only output cells of the cerebellar cortex.

    • This question is part of the following fields:

      • Neuro-anatomy
      6
      Seconds
  • Question 14 - Regarding CSF: ...

    Incorrect

    • Regarding CSF:

      Your Answer: Blockage of the foramina results in a communicating hydrocephalus

      Correct Answer: Disruption of arachnoid villi function results in a communicating hydrocephalus

      Explanation:

      In normal adults CSF volume is around 125ml to 150ml. Turnover of the entire volume of cerebrospinal fluid is about 3 to 4 times a day. Composition of CSF is similar to that of plasma except that CSF is nearly protein-free compared with plasma and has different electrolyte levels. Blockage of the foramina causes an obstructive or non-communicating hydrocephalus. Communicating hydrocephalus or non-obstructive hydrocephalus is caused by impaired CSF reabsorption in the absence of any CSF flow obstruction.

    • This question is part of the following fields:

      • Neuro-anatomy
      6.6
      Seconds
  • Question 15 - Choose the correct answer: fibers in the superior cerebellar peduncle: ...

    Incorrect

    • Choose the correct answer: fibers in the superior cerebellar peduncle:

      Your Answer: Are mainly lateral spinothalamic tracts

      Correct Answer: Are mainly ventral spinocerebellar tracts from the cerebellar nuclei to the thalamus and red nucleus

      Explanation:

      There are three cerebellar peduncles with different connections and functions. The three are mainly, superior, middle and inferior. The superior cerebellar peduncle is also known as the “Brachium conjunctivum”. It predominantly contains efferent fibers from the cerebellar nuclei, as well as some afferents from the spinocerebellar tract. The efferent pathways include cerebellorubral, dentatothalamic, and fastigioreticular fibers. These are tracts projecting from the deep cerebellar nuclei to the thalamus and red nucleus. The middle cerebellar peduncle connects to the pontine nucleus and the dorsal spinocerebellar tracts run through the superior cerebellar peduncle.

    • This question is part of the following fields:

      • Neuro-anatomy
      17.5
      Seconds
  • Question 16 - The inverse stretch reflex causing muscle relaxation when excessive force is applied to...

    Incorrect

    • The inverse stretch reflex causing muscle relaxation when excessive force is applied to a muscle is mediated by which sensory organ?

      Your Answer: Muscle stretch

      Correct Answer: Golgi tendon organ

      Explanation:

      Both the muscle spindle and Golgi tendon body are proprioceptors. The Golgi tendon reflex is a normal component of the reflex arc of the peripheral nervous system. In a Golgi tendon reflex, skeletal muscle contraction causes the antagonist muscle to simultaneously lengthen and relax. This reflex is also called the inverse myotatic reflex, because it is the inverse of the stretch reflex.

    • This question is part of the following fields:

      • Neuro-anatomy
      32.2
      Seconds
  • Question 17 - The main reason for the prolonged effect of the withdrawal reflex is: ...

    Incorrect

    • The main reason for the prolonged effect of the withdrawal reflex is:

      Your Answer: Slow afferent conduction

      Correct Answer: Multiple connections between afferent and efferent neurons

      Explanation:

      The withdrawal reflex is a spinal reflex that protects the body from harmful stimuli. Spinal reflexes are mostly monosynaptic and are mediated by a simple reflex arc. Withdrawal reflex is mediated by a polysynaptic reflex resulting in stimulation of many motor neurons in order to establish a quick and prolonged response.

    • This question is part of the following fields:

      • Neuro-anatomy
      58.9
      Seconds
  • Question 18 - The midbrain, medulla and pons, contain the following cranial nerve nuclei? ...

    Incorrect

    • The midbrain, medulla and pons, contain the following cranial nerve nuclei?

      Your Answer: CN 1 - 12

      Correct Answer: CN 3 - 12

      Explanation:

      The cranial nerves (with the exception of I and II) originate in the brainstem, which includes the midbrain, the pons, and the medulla.

    • This question is part of the following fields:

      • Neuro-anatomy
      37.4
      Seconds
  • Question 19 - Endolymph in the inner ear is rich in: ...

    Incorrect

    • Endolymph in the inner ear is rich in:

      Your Answer: Na

      Correct Answer: K

      Explanation:

      Cochlear fluids namely endolymph and perilymph have different compositions. Perilymph is a typical extracellular fluid, with ionic composition comparable to plasma or cerebrospinal fluid. The main cation is sodium. Endolymph is a totally unique extracellular fluid, with an ion composition unlike that which is found anywhere else in the body. The major cation in the endolymph is potassium and there is virtually no sodium.

    • This question is part of the following fields:

      • Neuro-anatomy
      28.5
      Seconds
  • Question 20 - In response to tissue injury, which of these cannot sensitize and activate nociceptors?...

    Incorrect

    • In response to tissue injury, which of these cannot sensitize and activate nociceptors?

      Your Answer: Serotonin

      Correct Answer: Calcium

      Explanation:

      Histamine, serotonin, bradykinin and prostaglandin are all chemical mediators of inflammation with different distinct functions however all activate nociceptors. Calcium on the other hand cannot sensitize or activate nociceptors.

    • This question is part of the following fields:

      • Neuro-anatomy
      9.4
      Seconds
  • Question 21 - The hippocampus is involved in the memory of: ...

    Incorrect

    • The hippocampus is involved in the memory of:

      Your Answer: Habituation

      Correct Answer: Facts

      Explanation:

      The hippocampus plays an important role in forming new memories about experienced events. Some researchers say that hippocampus plays a major role in declarative memory for example memory of facts.

    • This question is part of the following fields:

      • Neuro-anatomy
      43.9
      Seconds
  • Question 22 - The parasympathetic function of the facial nerve is: ...

    Incorrect

    • The parasympathetic function of the facial nerve is:

      Your Answer: Stimulation of the pilo-erector apparatus to conserve heat in the facial region

      Correct Answer: Secretion of tears from lacrimal glands, secretion of saliva from the sublingual and submandibular salivary glands.

      Explanation:

      Facial nerve (Cranial Nerve VII) has both sensory and motor components so it is a mixed nerve. It carries axons of:
      General somatic afferent – to skin and the posterior ear
      General visceral efferent – which innervate sublingual, submandibular and lacrimal glands and the mucosa of the nasal cavity.
      General visceral afferent – provide sensation to soft palate and parts of the nasal cavity.
      Special visceral efferent – innervate muscles of facial expression and stapedius, the posterior belly of the digastric and the stylohyoid muscles
      Special visceral afferent – provide taste to the anterior two-thirds of the tongue via chorda tympani.

    • This question is part of the following fields:

      • Neuro-anatomy
      21.8
      Seconds
  • Question 23 - The brainstem contains which of the following structures? ...

    Correct

    • The brainstem contains which of the following structures?

      Your Answer: The midbrain, pons and medulla

      Explanation:

      Brain stem is the base of the brain that connects the brain to the spinal cord. It consists of the mid brain, pons and medulla oblongata.

    • This question is part of the following fields:

      • Neuro-anatomy
      10.3
      Seconds
  • Question 24 - Which substance has the lowest taste threshold concentration, in other words which substance...

    Correct

    • Which substance has the lowest taste threshold concentration, in other words which substance can be present in the lowest concentration before taste buds will respond?

      Your Answer: Strychnine hydrochloride (bitter)

      Explanation:

      The lowest concentration of a gustatory stimulus to which the taste buds respond is considered to be the threshold concentration for that substance. The threshold concentration for strychnine is 0.0001 mm; this is because it allows the body to detect potentially dangerous substances (bitter plant components) at lower concentrations.

    • This question is part of the following fields:

      • Neuro-anatomy
      15.3
      Seconds
  • Question 25 - The primary auditory cortex is: ...

    Incorrect

    • The primary auditory cortex is:

      Your Answer: Brodmann area 44

      Correct Answer: Brodmann area 41

      Explanation:

      A Brodmann area in the brain is defined by cytoarchitecture, histology and organization of cells:
      Primary Sensory 3,1,2
      Primary Motor 4
      Premotor 6
      Primary Visual 17
      Primary Auditory 41
      Brocas 44

    • This question is part of the following fields:

      • Neuro-anatomy
      12.3
      Seconds
  • Question 26 - Concerning the sleep-wake cycle, Melatonin is secreted by which structure in the brain...

    Incorrect

    • Concerning the sleep-wake cycle, Melatonin is secreted by which structure in the brain following which environmental conditions?

      Your Answer:

      Correct Answer: Pineal gland, darkness

      Explanation:

      Melatonin is secreted by the pineal gland located in the midline attached to the posterior roof of the third ventricle in the brain. Melatonin affects circadian rhythm in the body or the sleep wake cycle. The precursor to melatonin is serotonin and the rate limiting enzyme that converts serotonin to melatonin is low during the day time and reaches its peak during the night.

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds
  • Question 27 - What is found in the posterior cavity of the eye? ...

    Incorrect

    • What is found in the posterior cavity of the eye?

      Your Answer:

      Correct Answer: Vitreous humor

      Explanation:

      The eye ball contains an anterior cavity and a posterior cavity. The anterior cavity once again is divided into the anterior chamber and posterior chamber. The anterior cavity is filled with aqueous humor whereas the posterior cavity contains vitreous humor.

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds
  • Question 28 - The basic taste “umami” is mediated by glutamate acting on a metabotropic receptor...

    Incorrect

    • The basic taste “umami” is mediated by glutamate acting on a metabotropic receptor named:

      Your Answer:

      Correct Answer: mGluR4

      Explanation:

      Umami taste or savoury taste is one of the five basic tastes described as meaty or brothy. The basic taste “umami” is mediated by glutamate acting on a metabotropic receptor named mGluR4 (metabotropic glutamate receptor 4). Additionally, umami taste is also mediated by the T1R1/T1R3 heterodimer, which is a combination of two G protein-coupled receptors. These receptors are responsible for detecting the presence of glutamate and other amino acids, contributing to the savory flavor characteristic of umami.

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds
  • Question 29 - Which neurotransmitter is found in the postganglionic parasympathetic synaptic cleft? ...

    Incorrect

    • Which neurotransmitter is found in the postganglionic parasympathetic synaptic cleft?

      Your Answer:

      Correct Answer: Acetylcholine

      Explanation:

      Acetylcholine is the neurotransmitter released from the postganglionic parasympathetic neuron into the synaptic cleft and also by some postganglionic sympathetic neurons as well.

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds
  • Question 30 - Afferent A δ fibers from nociceptors terminate primarily on neurons in which lamina:...

    Incorrect

    • Afferent A δ fibers from nociceptors terminate primarily on neurons in which lamina:

      Your Answer:

      Correct Answer: I and V

      Explanation:

      Nociceptors are receptors of pain sensation. There are 2 primary afferent/sensory pain fibers which transmit impulses from the receptor to the CNS, specifically to the dorsal horn of the spinal cord. The two fibers are A δ and C fibers. The dorsal horn of the spinal cord is the relay centre for sensory information converging from the periphery. Grey matter of the dorsal horn is subdivided in to laminae based on cytoarchitecture. C fibers terminate in lamina II the substantia gelatinosa. A δ fibers terminate primarily in lamina I but some project more deeply to terminate in lamina V.

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds

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