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Question 1
Correct
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Which of the following is NOT a contraindication to the use of diazepam:
Your Answer: Acute alcohol withdrawal
Explanation:Benzodiazepines are used to treat symptoms in patients with acute alcohol withdrawal syndrome.
Benzodiazepines are contraindicated in:
Respiratory depression
Marked neuromuscular respiratory weakness, such as unstable myasthenia gravis
Obstructive sleep apnoea syndrome (symptoms may be aggravated)
Severe hepatic impairment (the elimination half-life of diazepam may be prolonged; increased risk of coma)
Phobic or obsessional states, chronic psychosis or hyperkinesis (paradoxical reactions may occur). -
This question is part of the following fields:
- Anaesthesia
- Pharmacology
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Question 2
Correct
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Glucagon may be used as an antidote for overdose with which of the following:
Your Answer: Beta blockers
Explanation:Glucagon is a peptide hormone that is produced and secreted by alpha cells of the islets of Langerhans, which are located in the endocrine portion of the pancreas. The main physiological role of glucagon is to stimulate hepatic glucose output, thereby leading to increases in glycaemia. It provides the major counter-regulatory mechanism to insulin in maintaining glucose homeostasis.
Hypoglycaemia is the principal stimulus for the secretion of glucagon but may also be used as an antidote in beta-blocker overdose and in anaphylaxis in patients on beta-blockers that fail to respond to adrenaline.
Glucagon then causes:
Glycogenolysis
Gluconeogenesis
Lipolysis in adipose tissue
The secretion of glucagon is also stimulated by:
Adrenaline
Cholecystokinin
Arginine
Alanine
Acetylcholine
The secretion of glucagon is inhibited by:
Insulin
Somatostatin
Increased free fatty acids
Increased urea productionGlycolysis is the metabolic pathway that converts glucose into pyruvate. The free energy released by this process is used to form ATP and NADH. Glycolysis is inhibited by glucagon, and glycolysis and gluconeogenesis are reciprocally regulated so that when one cell pathway is activated, the other is inactive and vice versa.
Glucagon has a minor effect of enhancing lipolysis in adipose tissue. Lipolysis is the breakdown of lipids and involves the hydrolysis of triglycerides into glycerol and free fatty acids. It makes fatty acids available for oxidation.
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This question is part of the following fields:
- Endocrine
- Pharmacology
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Question 3
Incorrect
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The following statements concerning lung compliance is true EXCEPT?
Your Answer: Lung compliance comprises static and dynamic lung compliance
Correct Answer: Lung compliance is described by the equation: C = ∆ P/ ∆V, where C = compliance, P = pressure, and V = volume
Explanation:Lung compliance is the change in volume per unit change in distending pressure.
It is calculated using the equation:
Lung compliance = ΔV / ΔP
Where:
ΔV is the change in volume
ΔP is the change in pleural pressure.Lung compliance is inversely proportional to stiffness and elastance.
It comprises static (no airflow) and dynamic (during continuous breathing) components.
It is the slope of the pressure-volume curve.
Lung compliance describes the distensibility of the lungs and the chest wall.
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This question is part of the following fields:
- Physiology
- Respiratory Physiology
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Question 4
Incorrect
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Digoxin is contraindicated in all of the following EXCEPT for:
Your Answer: Wolff-Parkinson-White syndrome
Correct Answer: Asthma
Explanation:Digoxin is contraindicated in:Supraventricular arrhythmias associated with accessory conduction pathways e.g. Wolff-Parkinson-White syndromeVentricular tachycardia or fibrillationHeart conduction problems e.g. second degree or intermittent complete heart blockHypertrophic cardiomyopathy (unless concomitant atrial fibrillation and heart failure but should be used with caution)
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This question is part of the following fields:
- Cardiovascular
- Pharmacology
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Question 5
Correct
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A 29-year-old female with chronic anaemia secondary to sickle cell disease is being transfused. A few minutes after starting the blood transfusion, she develops widespread itching with urticarial rash, wheezing, nausea and chest pain. Her BP reduces to 60/40 mmHg.
What is the most appropriate treatment?Your Answer: Stop the transfusion and administer adrenaline
Explanation:Anaphylaxis transfusion reaction occurs when an individual has previously been sensitized to an allergen present in the blood and, on re-exposure, releases IgE or IgG antibodies. Patients with anaphylaxis usually develop laryngospasm, bronchospasm, abdominal pain, nausea, vomiting, hypotension, shock, and loss of consciousness. The transfusion should be stopped immediately and the patient should be treated with adrenaline, oxygen, corticosteroids, and antihistamines.
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This question is part of the following fields:
- Haematology
- Pathology
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Question 6
Incorrect
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A 36-year-old man who works in a farm presents with a deep laceration over the palm of his hand. A median nerve block was performed at his wrist to facilitate wound exploration and closure.
Which of the following statements regarding median nerve blocks at the wrist is considered correct?Your Answer: Palmaris longus can always be used to locate the median nerve
Correct Answer: The needle should be inserted approximately 2.5 cm proximal to flexor retinaculum
Explanation:A median nerve block is a simple, safe, and effective method of obtaining anaesthesia to the palmar aspect of the thumb, index finger, middle finger, radial portion of the palm and ring finger. The median nerve lies deep to the flexor retinaculum and about one centimetre under the skin of the volar wrist.
The palmaris longus tendon lies superficial to the retinaculum and is absent in up to 20% of patients.
The median nerve is located slightly lateral (radial) to the palmaris longus tendon and medial (ulnar) to the flexor carpi radialis tendon.The procedure is as follows:
– Check sensation and motor function of the median nerve. Wear gloves and use appropriate barrier precautions.
– Locate the flexor carpi radialis and palmaris longus tendons, which become prominent when the patient flexes the wrist against resistance. The palmaris longus tendon is usually the more prominent of the two tendons.
– Needle-entry site: The needle will be inserted adjacent to the radial (lateral) border of the palmaris longus tendon just proximal to the proximal wrist crease. If the palmaris longus tendon is absent, the needle-entry site is about 1 cm ulnar to the flexor carpi radialis tendon.
– Cleanse the site with antiseptic solution. Place a skin wheal of anaesthetic, if one is being used, at the needle-entry site.
– Insert the needle perpendicularly through the skin and advance it slowly until a slight pop is felt as the needle penetrates the flexor retinaculum. When paraesthesia in the distribution of the median nerve confirms proper needle placement, withdraw the needle 1 to 2 mm.
– Aspirate to exclude intravascular placement and then slowly (i.e., over 30 to 60 seconds) inject about 3 mL of anaesthetic. If the patient does not feel paraesthesia, redirect the needle in an ulnar direction, under the palmaris longus tendon. If paraesthesia is still not felt, slowly inject 3 to 5 mL of anaesthetic in the proximity of the nerve 1 cm deep to the tendon.
– Allow about 5 to 10 minutes for the anaesthetic to take effect. -
This question is part of the following fields:
- Anatomy
- Upper Limb
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Question 7
Correct
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Which of the following is NOT a common effect of etomidate:
Your Answer: Significant hypotension
Explanation:Etomidate causes less hypotension than thiopental sodium and propofol during induction. However, it is associated with a high incidence of extraneous muscle movements, which can be minimised by an opioid analgesic or a short-acting benzodiazepine given prior to induction. Pain on injection is common and there is a high rate of thrombophlebitis in the postoperative period. Postoperative nausea and vomiting commonly occur. Etomidate suppresses adrenocortical function, particularly during continuous administration, and it should not be used for maintenance of anaesthesia. It should be used with caution in patients with underlying adrenal insufficiency, for example, those with sepsis.
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This question is part of the following fields:
- Anaesthesia
- Pharmacology
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Question 8
Incorrect
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A 20-year-old male patient lives in a travelling community and has never received any vaccinations. He presents to you with fever.
Which of these statements concerning indications and contraindications for vaccination is FALSE?
Your Answer:
Correct Answer: Premature infants should have the their immunisation schedule adjusted for gestational age
Explanation:All vaccines are contraindicated in individuals with:
A confirmed anaphylactic reaction to a previous dose of the vaccine or a vaccine containing the same antigens.
A confirmed anaphylactic reaction to a component in the vaccine e.g. neomycinLive attenuated vaccines are contraindicated in pregnancy except in cases where risk of infection is more than the risks of vaccination.
During times of acute febrile illness, vaccination should be avoided.
12 weeks should elapse after a dose of human immunoglobulin before a live vaccine is administered.
The normal times recommended for immunization of full-term babies should also be applied to premature infants and correction for gestational age should NOT be implemented.
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This question is part of the following fields:
- Microbiology
- Principles Of Microbiology
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Question 9
Incorrect
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A 29 year old man presents to ED followed an alleged assault whilst out drinking. He received blunt trauma to his right axilla. He is complaining of difficulty abducting his right arm above the level of his shoulder, and on inspection, the inferior angle of his right scapula protrudes more than that of his left scapula. Which of the following nerves has most likely been affected:
Your Answer:
Correct Answer: Long thoracic nerve
Explanation:Damage to the long thoracic nerve results in weakness/paralysis of the serratus anterior muscle causing difficulty abducting the upper limb above 90 degrees and giving a ‘winged ‘ scapula appearance where the medial border, particularly the inferior angle, of the scapula moves laterally and posteriorly away from the thoracic wall (this becomes more pronounced if the patient presses the upper limb against a wall).
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This question is part of the following fields:
- Anatomy
- Upper Limb
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Question 10
Incorrect
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A patient who is taking ramipril for high blood pressure complains of a dry persistent cough. What is the mechanism of cough in ACE inhibitor therapy:
Your Answer:
Correct Answer: Decreased bradykinin breakdown
Explanation:Blocking ACE also diminishes the breakdown of the potent vasodilator bradykinin which is the cause of the persistent dry cough. Angiotensin-II receptor blockers do not have this effect, therefore they are useful alternative for patients who have to discontinue an ACE inhibitor because of persistent cough.
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This question is part of the following fields:
- Cardiovascular
- Pharmacology
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Question 11
Incorrect
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A patient presents with nausea, anorexia, jaundice and right upper quadrant pain. A diagnosis of acute hepatitis B is suspected.
Which of the following blood results is most suggestive of an acute hepatitis B infection? Select ONE answer only.Your Answer:
Correct Answer: HBsAg positive, IgM anti-HBc positive
Explanation:Hepatitis B surface antigen (HBsAg) is a protein on the surface of the hepatitis B virus, that is the first serologic marker to appear in a new acute infection.It can be detected as early as 1 week and as late as 9 weeks. It can be detected in high levels in serum during acute or chronic hepatitis B virus infection. The presence of HBsAg indicates that the person is infectious. The body normally produces antibodies to HBsAg as part of the normal immune response to infection. HBsAg is the antigen used to make hepatitis B vaccine.
Hepatitis B surface antibody (anti-HBs) indicates recovery and immunity from the hepatitis B virus infection. Anti-HBs also develops in a person who has been successfully vaccinated against hepatitis B.
Total hepatitis B core antibody (anti-HBc): Appears at the onset of symptoms in acute hepatitis B and persists for life. The presence of anti-HBc indicates previous or ongoing infection with hepatitis B virus in an undefined time frame. It is not present following hepatitis B vaccination.
IgM antibody to hepatitis B core antigen (IgM anti-HBc) indicates recent infection with hepatitis B virus (<6 months). Its presence indicates acute infection.
The following table summarises the presence of hepatitis B markers according to each situation:
Susceptible to infection:
HBsAg = Negative
Anti-HBc = Negative
Anti-HBs = NegativeImmune due to natural infection:
HBsAg = Negative
Anti-HBc = Positive
Anti-HBs = PositiveImmune due to vaccination:
HBsAg = Negative
Anti-HBc = Negative
Anti-HBs = PositiveAcute infection:
HBsAg = Positive
Anti-HBc = Positive
Anti-HBs = Negative
IgM anti-HBc = PositiveChronic infection:
HBsAg = Positive
Anti-HBc = Positive
Anti-HBs = Negative
IgM anti-HBc = Negative -
This question is part of the following fields:
- Microbiology
- Specific Pathogen Groups
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Question 12
Incorrect
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Regarding saliva, which of the following statements is CORRECT:
Your Answer:
Correct Answer: Saliva production is decreased by inhibition of the parasympathetic nervous system.
Explanation:At rest, saliva is predominantly produced by the submandibular gland (65%) but when stimulated, the parotid glands produce a higher proportion of the total saliva production (50%) than at rest. Saliva is alkaline and hypotonic to plasma. The predominant digestive enzymes in saliva are alpha-amylase and lingual lipase; lingual lipase is not functionally very important, but alpha-amylase is important for the initiation of starch digestion. Saliva production is decreased by inhibition of the parasympathetic nervous system e.g. by sleep, dehydration, anticholinergic drugs and fear.
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This question is part of the following fields:
- Gastrointestinal
- Physiology
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Question 13
Incorrect
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Regarding antihistamines, which of the following statements is CORRECT:
Your Answer:
Correct Answer: Elderly patients and children are more susceptible to side effects.
Explanation:Elderly patients and children are more susceptible to side effects. Antihistamines are competitive inhibitors at the H1-receptor. The newer antihistamines e.g. cetirizine cause less sedation and psychomotor impairment than the older antihistamines because they are much less lipid soluble and penetrate the blood brain barrier only to a slight extent. Antihistamines are used as a second line adjunct to adrenaline in anaphylaxis.
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This question is part of the following fields:
- Pharmacology
- Respiratory
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Question 14
Incorrect
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Despite taking the oral contraceptive pill, a 29-year-old woman becomes pregnant. During a medication review, you discover that she is epileptic and that her antiepileptic therapy has recently been changed.
Which of the following antiepileptics is most likely to impair the oral contraceptive pill's effectiveness?Your Answer:
Correct Answer: Carbamazepine
Explanation:The metabolism of ethinyl oestradiol and progestogens has been shown to be increased by enzyme-inducing antiepileptics. The oral contraceptive pill (OCP) is less effective in preventing pregnancy as a result of this increased breakdown.
Antiepileptic drugs that induce enzymes include:
Carbamazepine
Phenytoin
Phenobarbital
TopiramateAntiepileptics that do not induce enzymes are unlikely to affect contraception. Non-enzyme-inducing anticonvulsants include the following:
Clonazepam
Gabapentin
Levetiracetam
Piracetam
Sodium valproate is a type of valproate that is used toLamotrigine is an antiepileptic drug that does not cause the production of enzymes. It does, however, require special consideration, unlike other non-enzyme-inducing antiepileptics. The OCP does not appear to affect epilepsy directly, but it does appear to lower lamotrigine levels in the blood. This could result in a loss of seizure control and the occurrence of seizures.
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This question is part of the following fields:
- CNS Pharmacology
- Pharmacology
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Question 15
Incorrect
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A patient is currently taking is glyceryl trinitrate among other chronic medications. Which of the following side effects is he LEAST likely to develop?
Your Answer:
Correct Answer: Syncope
Explanation:Nitrates are used in the treatment of angina pectoris and the prevention of myocardial ischaemia. Commonly used examples of nitrates are glyceryl trinitrate and isosorbide dinitrate. Unwanted effects, however, are common and can limit therapy, particularly when angina is severe or when patients are unusually sensitive to the effects of nitrates.
The following are common or very common side effects of nitrates:
- Arrhythmias
- Asthenia
- Cerebral ischaemia
- Dizziness
- Drowsiness
- Flushing
- Headache
- Hypotension
- Nausea and vomiting
- Diarrhoea, syncope and cyanosis can occur, but these are rare side effects.
Dry eyes, bradycardia and metabolic acidosis have not been reported.
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This question is part of the following fields:
- Cardiovascular Pharmacology
- Pharmacology
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Question 16
Incorrect
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Which of the following is NOT a mineralocorticoid effect of corticosteroids:
Your Answer:
Correct Answer: Hyperglycaemia
Explanation:Mineralocorticoid side effects include:hypertensionsodium retentionwater retention and oedemapotassium losscalcium loss
Glucocorticoid side effects include:weight gainhyperglycaemia and diabetesosteoporosis and osteoporotic fracturesmuscle wasting (proximal myopathy)peptic ulceration and perforationpsychiatric reactions -
This question is part of the following fields:
- Endocrine
- Pharmacology
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Question 17
Incorrect
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Regarding skeletal muscle contraction, which of the following statements is CORRECT:
Your Answer:
Correct Answer: The force of contraction of a muscle can be controlled by increasing recruitment of motor units.
Explanation:Each motor unit contracts in an all or nothing fashion, i.e. if a motor unit is excited, it will stimulate all of its muscle fibres to contract. The force of contraction of a muscle is controlled by varying the motor unit recruitment (spatial summation), and by varying the firing rate of the motor units (temporal summation). During a gradual increase in contraction of a muscle, the first units start to discharge and increase their firing rate, and, as the force needs to increase, new units are recruited and, in turn, also increase their firing rate. For most motor units, the firing rate for a steady contraction is between 5 and 8 Hz. Because the unitary firing rates for each motor unit are different and not synchronised, the overall effect is a smooth force profile from the muscle. Increasing the firing rate of motor units is temporal summation where the tension developed by the first action potential has not completely decayed when the second action potential and twitch is grafted onto the first and so on. If the muscle fibres are stimulated repeatedly at a faster frequency, a sustained contraction results where it is not possible to detect individual twitches. This is called tetanus.
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This question is part of the following fields:
- Basic Cellular
- Physiology
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Question 18
Incorrect
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Urine flow rate = 2 ml/min
Urine concentration of creatinine = 18 mg/ml
Plasma concentration of creatinine = 0.25 mg/ml
What is the estimated glomerular filtration rate (eGFR)?
Your Answer:
Correct Answer: 144 ml/min
Explanation:GFR can be estimated by:
GFR = UCr x V / PCr
Where:
UCr = urine concentration of creatinine
PCr = plasma concentration of creatinine
V = rate of urine flowIn this case GFR = (18 x 2) / 0.25 = 144 ml/min
Note: Creatinine is used to estimate GFR because it is an organic base naturally produced by muscle breakdown, it is freely filtered at the glomerulus, it is not reabsorbed from the nephron, it is not produced by the kidney, it is not toxic, and it doesn’t alter GFR.
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This question is part of the following fields:
- Physiology
- Renal Physiology
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Question 19
Incorrect
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You plan to use plain 1% lidocaine for a ring block on a finger that needs suturing.
Which SINGLE statement regarding the use of 1% lidocaine, in this case, is true?Your Answer:
Correct Answer: Lidocaine works by blocking fast voltage-gated sodium channels
Explanation:Lidocaine is a tertiary amine that is primarily used as a local anaesthetic but can also be used intravenously in the treatment of ventricular dysrhythmias.
Lidocaine works as a local anaesthetic by diffusing in its uncharged base form through neural sheaths and the axonal membrane to the internal surface of the cell membrane sodium channels. Here it alters signal conduction by blocking the fast voltage-gated sodium channels. With sufficient blockage, the membrane of the postsynaptic neuron will not depolarise and will be unable to transmit an action potential, thereby preventing the transmission of pain signals.
Each 1 ml of plain 1% lidocaine solution contains 10 mg of lidocaine hydrochloride. The maximum safe dose of plain lidocaine is 3 mg/kg. When administered with adrenaline 1:200,000, the maximum safe dose is 7 mg/kg. Because of the risk of vasoconstriction and tissue necrosis, lidocaine should not be used in combination with adrenaline in extremities such as fingers, toes, and the nose.
The half-life of lidocaine is 1.5-2 hours. Its onset of action is rapid within a few minutes, and it has a duration of action of 30-60 minutes when used alone. Its duration of action is prolonged by co-administration with adrenaline (about 90 minutes).
Lidocaine tends to cause vasodilatation when used locally. This is believed to be due mainly to the inhibition of action potentials via sodium channel blocking in vasoconstrictor sympathetic nerves. -
This question is part of the following fields:
- Anaesthesia
- Pharmacology
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Question 20
Incorrect
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A patient who has a nerve injury has sparing of the upper half of the orbicularis oculi muscle but not the lower half. Which branch of the facial nerve supplies the lower half of the orbicularis oculi?
Your Answer:
Correct Answer: Zygomatic branch
Explanation:The facial nerve divides into five terminal branches once in the parotid gland.
1. The temporal branch innervates muscles in the temple, forehead and supraorbital areas.
2. The zygomatic branch innervates muscles in the infraorbital area, the lateral nasal area and the upper lip.
3. The buccal branch innervates muscles in the cheek, the upper lip and the corner of the mouth.
4. The marginal mandibular branch innervates muscles of the lower lip and chin.
5. The cervical branch innervates the platysma muscle. -
This question is part of the following fields:
- Anatomy
- Cranial Nerve Lesions
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Question 21
Incorrect
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By the third day of wound healing, which sort of inflammatory cell has predominated:
Your Answer:
Correct Answer: Macrophages
Explanation:The inflammatory phase of healing is sometimes called the lag phase because wound strength does not begin to return immediately. The inflammatory phase is completed within three days except in the presence of infection or other factors associated with impaired wound healing. Mononuclear leukocytes accumulate and are transformed into macrophages. The maturation of blood-derived monocytes into macrophages is heralded by several events, including secretion of vimentin, which is a structural filament protein involved in wound healing.
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This question is part of the following fields:
- Pathology
- Wound Healing
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Question 22
Incorrect
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Renal potassium excretion is promoted by all but which one of the following:
Your Answer:
Correct Answer: Increased intracellular magnesium
Explanation:Aldosterone: A rise in [K+] in the extracellular fluid of the adrenal cortex directly stimulates aldosterone release. Aldosterone promotes the synthesis of Na+/K+ATPases and the insertion of more Na+/K+ATPases into the basolateral membrane, and also stimulates apical sodium and potassium channel activity, overall acting to increase sodium reabsorption and potassium secretion.
pH changes: Potassium secretion is reduced in acute acidosis and increased in acute alkalosis. A higher pH increases the apical K+channel activity and the basolateral Na+/K+ATPase activity – both changes that promote K+secretion.
Flow rates: Increased flow rates in the collecting duct reduce K+concentration in the lumen and therefore enhance K+secretion. Increased flow also activates BK potassium channels, and ENaC channels which promote potassium secretion and sodium reabsorption respectively.
Sodium delivery: Decreased Na+delivery to the collecting ducts results in less Na+reabsorption and hence a reduced gradient for K+secretion.
Magnesium: Intracellular magnesium can bind and block K+channels inhibiting K+secretion into the tubules. Therefore magnesium deficiency reduces this inhibitory effect and so allows more potassium to be secreted into tubules and can cause hypokalaemia. -
This question is part of the following fields:
- Physiology
- Renal
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Question 23
Incorrect
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Which of the following microbes produces exotoxin:
Your Answer:
Correct Answer: Clostridium tetani
Explanation:Clostridium tetani (causing tetanus) produces the exotoxin tetanospasmin which causes its neurotoxic effects.
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This question is part of the following fields:
- Microbiology
- Principles
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Question 24
Incorrect
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A 23-year-old female has been prescribed a medication in the first trimester of pregnancy due to a life-threatening medical problem. After delivery, the foetus is found to have nasal hypoplasia, stippling of his bones and atrophy of bilateral optic discs along with growth retardation.
Which ONE of the following drugs has this woman most likely received?Your Answer:
Correct Answer: Warfarin
Explanation:Warfarin is teratogenic and can cause a host of abnormalities in the growing foetus. These include hypoplasia of the nasal bridge, stippling of the epiphyses, multiple ophthalmic complications, growth retardation, pectus carinatum, atrial septal defect, ventriculomegaly and a patent ductus arteriosus.
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This question is part of the following fields:
- Cardiovascular Pharmacology
- Pharmacology
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Question 25
Incorrect
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Which statement regarding skeletal muscle is true?
Your Answer:
Correct Answer: Myosin is the major constituent of the thick filament
Explanation:Myosin is the major constituent of the thick filament.
Actin is the major constituent of the THIN filament.
Thin filaments consist of actin, tropomyosin and troponin in the ratio 7:1:1.
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This question is part of the following fields:
- Basic Cellular Physiology
- Physiology
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Question 26
Incorrect
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Gastrin release from antral G-cells is inhibited by all but which one of the following:
Your Answer:
Correct Answer: Vagal stimulation
Explanation:Gastrin secretion is inhibited by:
Low gastric pH (negative feedback mechanism)
Somatostatin
Secretin
Gastric inhibitory polypeptide (GIP)
Cholecystokinin -
This question is part of the following fields:
- Gastrointestinal
- Physiology
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Question 27
Incorrect
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Regarding the intervertebral disc, which of the following statements is CORRECT:
Your Answer:
Correct Answer: In L4 - L5 disc herniation, the L5 spinal nerve root is the most commonly affected.
Explanation:A posterolateral herniation of the disc at the L4 – L5 level would be most likely to damage the fifth lumbar nerve root, not the fourth lumbar nerve root, due to more oblique descending of the fifth lumbar nerve root within the subarachnoid space.
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This question is part of the following fields:
- Anatomy
- Head And Neck
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Question 28
Incorrect
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A 66-year-old female presents to the Emergency Department with a nose bleed. She says that she has been having frequent episodes of nose bleeds over the past four months, along with increasing fatigue and some weight loss. On examination, she has a diffuse petechial rash and hypertrophy of the gingiva.
Which one of the following conditions is this patient most likely to have?Your Answer:
Correct Answer: Acute myeloid leukaemia (AML)
Explanation:The history of nosebleeds and fatigue, and gingival hyperplasia presents a typical picture of acute myeloid leukaemia. Leukemic infiltrates within the gingiva cause hypertrophy and distinguish this condition from other types of leukaemia. The fatigue is secondary to anaemia, while the nosebleeds are caused by thrombocytopenia secondary to leukemic infiltration of bone marrow. Patients may also report frequent infections secondary to neutropenia and hepatosplenomegaly.
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This question is part of the following fields:
- Haematology
- Pathology
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Question 29
Incorrect
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The following structures all lie anteriorly to the oesophagus EXCEPT for the:
Your Answer:
Correct Answer: Thoracic duct
Explanation:Posterior to the oesophagus, the thoracic duct is on the right side inferiorly but crosses to the left more superiorly (at T5).
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This question is part of the following fields:
- Anatomy
- Thorax
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Question 30
Incorrect
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A patient suffers a lower limb fracture that causes damage to the nerve that innervates peroneus brevis.
Peroneus brevis receives its innervation from which of the following nerves? Select ONE answer only.Your Answer:
Correct Answer: Superficial peroneal nerve
Explanation:Peroneus brevis is innervated by the superficial peroneal nerve.
Peroneus longus is innervated by the superficial peroneal nerve.
Peroneus tertius is innervated by the deep peroneal nerve. -
This question is part of the following fields:
- Anatomy
- Lower Limb
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SESSION STATS - PERFORMANCE PER SPECIALTY
