00
Correct
00
Incorrect
00 : 00 : 00
Session Time
00 : 00
Average Question Time ( Mins)
  • Question 1 - You're currently treating an infection in a patient and trying to figure out...

    Correct

    • You're currently treating an infection in a patient and trying to figure out which antibiotic would be best.

      Which of the following antimicrobial drugs inhibits the formation of cell walls?

      Your Answer: Cefuroxime

      Explanation:

      Cefuroxime and other cephalosporin antibiotics are bactericidal ß-lactam antibiotics. They work similarly to penicillins in that they prevent cross-linking between the linear peptidoglycan polymer chains that make up the bacterial cell wall. As a result, they prevent the formation of cell walls.
      The following is a summary of the various mechanisms of action of various types of antimicrobial agents:

      1) Inhibition of cell wall synthesis
      Penicillins
      Cephalosporins
      Vancomycin

      2) Disruption of cell membrane function
      Polymyxins
      Nystatin
      Amphotericin B

      3) Inhibition of protein synthesis
      Macrolides
      Aminoglycosides
      Tetracyclines
      Chloramphenicol

      4) Inhibition of nucleic acid synthesis
      Quinolones
      Trimethoprim
      5-nitroimidazoles
      Rifampicin

      5) Anti-metabolic activity
      Sulphonamides
      Isoniazid

    • This question is part of the following fields:

      • Infections
      • Pharmacology
      28.7
      Seconds
  • Question 2 - Regarding aspirin at analgesic doses, which of the following statements is CORRECT: ...

    Incorrect

    • Regarding aspirin at analgesic doses, which of the following statements is CORRECT:

      Your Answer: As an analgesic, it has duration of action about 12 hours.

      Correct Answer: It is contraindicated in patients with severe heart failure.

      Explanation:

      Aspirin (at analgesic doses) is contraindicated in severe heart failure. Aspirin irreversibly inhibits cyclooxygenase (COX) enzymes resulting in decreased production of prostaglandins (which can lead to irritation of the gastric mucosa). The analgesic dose is greater than the antiplatelet dose, and taken orally it has a duration of action of about 4 hours. Clinical features of salicylate toxicity in overdose include hyperventilation, tinnitus, deafness, vasodilatation, and sweating.

    • This question is part of the following fields:

      • Central Nervous System
      • Pharmacology
      45.6
      Seconds
  • Question 3 - The patient is a 61-year-old man with severe central chest pain. An acute...

    Correct

    • The patient is a 61-year-old man with severe central chest pain. An acute myocardial infarction is revealed by his ECG. Clopidogrel is one of the medications he takes as part of his treatment.

      Clopidogrel's direct mechanism of action is which of the following?

      Your Answer: Inhibition of platelet ADP receptors

      Explanation:

      Clopidogrel, a thienopyridine derivative, prevents platelet aggregation and cross-linking by the protein fibrin by inhibiting the ADP receptor on platelet cell membranes (inhibits binding of ADP to its platelet receptor (P2Y12 ADP-receptor).

    • This question is part of the following fields:

      • Cardiovascular Pharmacology
      • Pharmacology
      44
      Seconds
  • Question 4 - Which of the following muscles are primarily involved in passive inspiration: ...

    Correct

    • Which of the following muscles are primarily involved in passive inspiration:

      Your Answer: Diaphragm and external intercostal muscles

      Explanation:

      Passive inspiration is produced by contraction of the diaphragm (depressing the diaphragm) and the external intercostal muscles (elevating the ribs). In inspiration, elevation of the sternal ends of the ribs (‘pump handle’ movement), elevation of the lateral shafts of the ribs (‘bucket handle’ movement) and depression of the diaphragm result in expansion of the thorax in an anteroposterior, transverse and vertical direction respectively. This results in an increased intrathoracic volume and decreased intrathoracic pressure and thus air is drawn into the lungs.

    • This question is part of the following fields:

      • Anatomy
      • Thorax
      1199.6
      Seconds
  • Question 5 - The percentage of patients with hepatitis B that develop chronic infection is about:...

    Correct

    • The percentage of patients with hepatitis B that develop chronic infection is about:

      Your Answer: 10%

      Explanation:

      With hepatitis B, about 90% of people will develop lifelong immunity after clearing the infection. Chronic hepatitis develops in about 10% of patients and this may be complicated by cirrhosis or hepatocellular carcinoma. There is a very high risk of chronic infection and hepatocellular carcinoma when there is congenital infection. The risk of this in healthy adults is only about 5%.

    • This question is part of the following fields:

      • Microbiology
      • Pathogens
      9.8
      Seconds
  • Question 6 - Which among the following antibacterial regimens is considered the most appropriate to prescribe...

    Correct

    • Which among the following antibacterial regimens is considered the most appropriate to prescribe in a patient presenting with clinical signs and symptoms consistent with a diagnosis of pelvic inflammatory disease?

      Your Answer: Ceftriaxone plus doxycycline plus metronidazole

      Explanation:

      The endocervix is the most common site of Neisseria gonorrhoeae infection in women. Symptoms of infection, when present, include dysuria, cervical discharge, and lower abdominal pain. However, 50% of cases in women may be asymptomatic leading to complications such as pelvic inflammatory disease (PID), which may cause sterility, ectopic pregnancy, or perihepatitis.

      PID is also known as Fitz-Hugh-Curtis syndrome is defined as an inflammation of the upper genital tract due to an infection in women. The disease affects the uterus, fallopian tubes, and ovaries. It is typically an ascending infection, spreading from the lower genital tract.

      The recommended intramuscular or oral regimens for PID are as follows:

      Ceftriaxone at 500 mg IM in a single dose (for persons weighing ≥150 kg, administer 1 g of ceftriaxone); plus doxycycline at 100 mg PO BID for 14 days with metronidazole at 500 mg PO BID for 14 days.

    • This question is part of the following fields:

      • Microbiology
      • Specific Pathogen Groups
      17.5
      Seconds
  • Question 7 - Which of the following nerves innervates the gastrocnemius muscle? ...

    Incorrect

    • Which of the following nerves innervates the gastrocnemius muscle?

      Your Answer: Sciatic nerve

      Correct Answer: Tibial nerve

      Explanation:

      The gastrocnemius is innervated by the anterior rami of S1 and S2 spinal nerves, carried by the tibial nerve into the posterior compartment of the leg.

    • This question is part of the following fields:

      • Anatomy
      • Lower Limb
      13.1
      Seconds
  • Question 8 - A 25-year-old guy who has had a knee-high plaster cast on his left...

    Correct

    • A 25-year-old guy who has had a knee-high plaster cast on his left leg for the past 5 weeks arrives at the emergency department complaining of numbness on the dorsum of his left foot and an inability to dorsiflex or evert his foot. You know that his symptoms are due to fibular nerve compression. Where is the fibular nerve located?

      Your Answer: Neck of fibula

      Explanation:

      Dorsiflexion and eversion of the foot are innervated by the deep fibular nerve and the superficial fibular nerve, respectively.

      The common fibular nerve runs obliquely downward along the lateral border of the popliteal fossa (medial to the biceps femoris) before branching at the neck of the fibula.

      Thus, it is prone to being affected during an impact injury or fracture to the bone or leg. Casts that are placed too high can also compress the fibular nerve.

    • This question is part of the following fields:

      • Anatomy
      • Lower Limb
      62.5
      Seconds
  • Question 9 - A 62-year-old woman has reduced urine output, nausea, and confusion. Renal function tests...

    Incorrect

    • A 62-year-old woman has reduced urine output, nausea, and confusion. Renal function tests and other investigations done leads to a diagnosis of acute kidney injury (AKI). Which one of these is consistent with a diagnosis of AKI?

      Your Answer: A 25% increase in serum creatinine within the preceding seven days

      Correct Answer: A rise in serum creatinine of 26 μmol/L within 48 hours

      Explanation:

      AKI is diagnosed based on an acutely rising serum creatinine and/or reduction in urine output.

      • AKI can often be non-oliguric.

      AKI is present if any one or more of the following criteria is met:

      • A rise in serum creatinine of ≥26 micromol/L (≥0.3 mg/dL) within 48 hours

      • A rise in serum creatinine to ≥1.5 times baseline, which is known or presumed to have occurred within the past 7 days (in practice you can use the lowest value from the past 3 months as the baseline for the patient)

      • Urine volume <0.5 ml/kg/hour for at least 6 hours.

       

    • This question is part of the following fields:

      • General Pathology
      • Pathology
      3225.9
      Seconds
  • Question 10 - Which of the following is NOT a function of the commensal intestinal bacterial...

    Correct

    • Which of the following is NOT a function of the commensal intestinal bacterial flora:

      Your Answer: Breakdown of haem into bilirubin

      Explanation:

      Commensal intestinal bacterial flora have a role in:Keeping pathogenic bacteria at bay by competing for space and nutrientConverting conjugated bilirubin to urobilinogen (some of which is reabsorbed and excreted in urine) and stercobilinogen which is excreted in the faecesThe synthesis of vitamins K, B12, thiamine and riboflavinThe breakdown of primary bile acids to secondary bile acidsThe breakdown of cholesterol, some food additives and drugs

    • This question is part of the following fields:

      • Gastrointestinal
      • Physiology
      105.4
      Seconds
  • Question 11 - A thyroid function test is done for a 55-year-old woman with non-specific symptoms,...

    Incorrect

    • A thyroid function test is done for a 55-year-old woman with non-specific symptoms, the results are shown below:
      TSH = 5.2
      Free T4 is normal
      Free T3 is normal

      The most likely diagnosis in this patient is?

      Your Answer: No significant abnormality detected

      Correct Answer: Subclinical hypothyroidism

      Explanation:

      Hypothyroidism is diagnosed using the results of thyroid function tests (TFTs).

      In the early stages of the disease, the earliest biochemical change noticed is a rise in thyroid-stimulating hormone (TSH) levels. Free triiodothyronine (T3) and thyroxine (T4) levels are usually normal.

      In primary hypothyroidism, the serum TSH level is usually greater than 10 mU/L, and free T4 levels are below the reference range.

      Subclinical hypothyroidism is diagnosed when the serum TSH level is above the reference range, and the free T4 levels are within the reference range. The test should, however, be repeated after 3-6 months to exclude transient causes of raised TSH.

      In summary, how to interpret TFTs in cases of suspected hypothyroidism is shown below:

      Subclinical hypothyroidism
      TSH is raised
      Free T4 is normal
      Free T3 is normal

      Primary hypothyroidism
      TSH is raised
      Free T4 is lowered
      Free T3 is lowered or normal

      Secondary hypothyroidism
      TSH is lowered or normal
      Free T4 is lowered
      Free T3 is lowered or normal

    • This question is part of the following fields:

      • Endocrine Physiology
      • Physiology
      52.5
      Seconds
  • Question 12 - Intrinsic factor is secreted by which of the following cell types in the...

    Incorrect

    • Intrinsic factor is secreted by which of the following cell types in the stomach:

      Your Answer: Principal cells

      Correct Answer: Parietal cells

      Explanation:

      Intrinsic factor is essential for the absorption of the small amounts of vitamin B12 normally present in the diet from the terminal ileum. The parietal cells of the stomach produce intrinsic factor, and following a gastrectomy, the absorption of vitamin B12 will be markedly reduced, and a deficiency state will exist.

    • This question is part of the following fields:

      • Gastrointestinal
      • Physiology
      10.8
      Seconds
  • Question 13 - Regarding benzylpenicillin, which of the following statements is CORRECT: ...

    Correct

    • Regarding benzylpenicillin, which of the following statements is CORRECT:

      Your Answer: If meningococcal disease is suspected, benzylpenicillin should be given before transfer to hospital.

      Explanation:

      Benzylpenicillin (although inactivated by bacterial beta-lactamases) is effective for many streptococcal (including pneumococcal), gonococcal, and meningococcal infections and also for anthrax, diphtheria, gas gangrene, leptospirosis, and treatment of Lyme disease. If meningococcal disease (meningitis with non-blanching rash or meningococcal septicaemia) is suspected, benzylpenicillin should be given before transfer to hospital, so long as this does not delay the transfer; benzylpenicillin is no longer the drug of first choice for pneumococcal meningitis. Although benzylpenicillin is effective in the treatment of tetanus, metronidazole is preferred. Benzylpenicillin is inactivated by gastric acid and absorption from the gastrointestinal tract is poor and therefore it must be given by injection.

    • This question is part of the following fields:

      • Infections
      • Pharmacology
      265.2
      Seconds
  • Question 14 - Fibrinoid necrosis is typically seen in which of the following: ...

    Correct

    • Fibrinoid necrosis is typically seen in which of the following:

      Your Answer: Malignant hypertension

      Explanation:

      Fibrinoid necrosis occurs in malignant hypertension where increased arterial pressure results in necrosis of smooth muscle wall. Eosinophilic and fibrinous deposits are seen.

    • This question is part of the following fields:

      • Inflammatory Responses
      • Pathology
      26.8
      Seconds
  • Question 15 - In which part of the gastrointestinal tract is Meckel's diverticulum commonly located? ...

    Incorrect

    • In which part of the gastrointestinal tract is Meckel's diverticulum commonly located?

      Your Answer: Caecum

      Correct Answer: Ileum

      Explanation:

      Meckel’s diverticulum is the most prevalent congenital anomaly of the gastrointestinal tract, affecting approximately 2% of the general population. Meckel’s diverticulum are designated true diverticula because their walls contain all the layers found in normal small intestine. Their location varies among individual patients, but they are usually found in the ileum within 100 cm of the ileocecal valve.

      Approximately 60% of Meckel’s diverticulum contain heterotopic mucosa, of which over 60% consist of gastric mucosa. Pancreatic acini are the next most common; others include Brunner’s glands, pancreatic islets, colonic mucosa, endometriosis, and hepatobiliary tissues.

      A useful, although crude, mnemonic describing Meckel’s diverticulum is the “rule of twos”: 2% prevalence, 2:1 male predominance, location 2 feet proximal to the ileocecal valve in adults, and half of those who are symptomatic are under 2 years of age.

    • This question is part of the following fields:

      • Abdomen And Pelvis
      • Anatomy
      30.8
      Seconds
  • Question 16 - A 59-year-old man is complaining of pain in his perineal area, a recent...

    Incorrect

    • A 59-year-old man is complaining of pain in his perineal area, a recent onset of urinary frequency and urgency, fever, chills, and muscle aches. He has a long history of nocturia and terminal dribbling. On rectal examination you find an exquisitely tender prostate.

      Which of these antibacterial agents would be most appropriate in this case?

      Your Answer: Co-amoxiclav for 28 days

      Correct Answer: Ciprofloxacin for 14 days

      Explanation:

      An acute focal or diffuse suppurative inflammation of the prostate gland is called acute bacterial prostatitis.

      According to the National Institute for Health and Care Excellence (NICE), acute prostatitis should be suspected in a man presenting with:
      A feverish illness of sudden onset which may be associated with rigors, arthralgia, or myalgia; Irritative urinary voiding symptoms; acute urinary retention; perineal or suprapubic pain and an exquisitely tender prostate on rectal examination.

      Treatment of acute prostatitis as recommended by NICE and the BNFare:
      Ciprofloxacin or ofloxacin for 14 days
      Alternatively, trimethoprim can be used. Duration of treatment is still 14 days

    • This question is part of the following fields:

      • Microbiology
      • Specific Pathogen Groups
      115.6
      Seconds
  • Question 17 - A 28-year-old woman with history of blunt thoracic trauma develops hypotension chest pain,...

    Incorrect

    • A 28-year-old woman with history of blunt thoracic trauma develops hypotension chest pain, and breathlessness. A bedside echocardiogram was performed and revealed a large pericardial effusion. Due to this finding, a pericardiocentesis was to be performed.

      Which of the following statements is considered true regarding pericardiocentesis?

      Your Answer: The patient should be lying flat during the procedure

      Correct Answer: The needle should be aimed at the midpoint of the left clavicle

      Explanation:

      Pericardiocentesis is a procedure done to remove fluid build-up in the sac around the heart known as the pericardium. The pericardium can be tapped from almost any reasonable location on the chest wall. However, for the usual blind pericardiocentesis, the subxiphoid approach is preferred. Ideally, 2-D echocardiography is used to guide needle insertion and the subsequent path of the needle/catheter.

      In the subxiphoid approach, the needle is inserted 1 cm inferior to the left xiphocostal angle with an angle of 30 degrees from the patient’s chest with a direction towards the left mid-clavicle.

      The fingers may sense a distinct give when the needle penetrates the parietal pericardium. Successful removal of fluid confirms the needle’s position.

    • This question is part of the following fields:

      • Anatomy
      • Thorax
      2758.2
      Seconds
  • Question 18 - How does an action potential in the motor end plate rapidly spread to...

    Correct

    • How does an action potential in the motor end plate rapidly spread to the central portions of the muscle cells?

      Your Answer: Transverse tubules

      Explanation:

      When the concentration of intracellular Ca2+rises, muscle contraction occurs. The pathway of an action potential is down tube-shaped invaginations of the sarcolemma called T-tubules (transverse tubules). These penetrate throughout the muscle fibre and lie adjacent to the terminal cisternae of the sarcoplasmic reticulum. The voltage changes in the T-tubules result in the opening of sarcoplasmic reticulum Ca2+channels and there is there is release of stored Ca2+into the sarcoplasm. Thus muscle contraction occurs via excitation-contraction coupling (ECC) mechanism.

    • This question is part of the following fields:

      • Basic Cellular
      • Physiology
      13.3
      Seconds
  • Question 19 - What type of pump is the Na+/K+ATPase pump? ...

    Incorrect

    • What type of pump is the Na+/K+ATPase pump?

      Your Answer: A symporter

      Correct Answer: An antiporter

      Explanation:

      In order for primary active transport to pump ions against their electrochemical gradient, chemical energy is used in the form of ATP. This is facilitated by the Na+/K+-ATPase antiporter pump, which uses metabolic energy to move 3 Na+ions out of the cell for every 2 K+ions that come in, against their respective electrochemical gradients. As a result, the cell the maintains a high intracellular concentration of K+ions and a low concentration of Na+ions.

    • This question is part of the following fields:

      • Basic Cellular
      • Physiology
      9.1
      Seconds
  • Question 20 - A tumour compresses the jugular foramen of a 50-year-old patient. Compression of several...

    Incorrect

    • A tumour compresses the jugular foramen of a 50-year-old patient. Compression of several nerves in the jugular foramen will result in which of the following complications?

      Your Answer: Loss of sensation over the face

      Correct Answer: Loss of gag reflex

      Explanation:

      The glossopharyngeal nerve, which is responsible for the afferent pathway of the gag reflex, the vagus nerve, which is responsible for the efferent pathway of the gag reflex, and the spinal accessory nerve all exit the skull through the jugular foramen. These nerves are most frequently affected if the jugular foramen is compressed. As a result, the patient’s gag reflex is impaired.

      The vestibulocochlear nerve is primarily responsible for hearing. The trigeminal nerve provides sensation in the face. The facial nerve innervates the muscles of face expression (including those responsible for closing the eye). Tongue motions are controlled mostly by the hypoglossal nerve.

    • This question is part of the following fields:

      • Anatomy
      • Cranial Nerve Lesions
      19.4
      Seconds
  • Question 21 - A 10-year-old girl presents with polyuria, polydipsia, and stomach pain. She has a...

    Incorrect

    • A 10-year-old girl presents with polyuria, polydipsia, and stomach pain. She has a history of type I diabetes mellitus. On blood gas analysis, she has metabolic acidosis. Diabetic ketoacidosis (DKA) is diagnosed, and therapy is initiated. She becomes increasingly confused when intravenous fluids and insulin are administered.

      Which electrolyte imbalance is the MOST likely reason of the increased confusion

      Your Answer: Hypokalaemia

      Correct Answer: Hyponatraemia

      Explanation:

      Because of the shift of water from the intracellular to the extracellular compartment as a result of hyperglycaemia and increased plasma osmolality, dilutional hyponatraemia is common in diabetic ketoacidosis (DKA).

      If intravenous fluids are not delivered with caution, hyponatraemia might worsen, which can lead to increased degrees of disorientation. Hyponatraemia has also been linked to an increased risk of cerebral oedema, especially if blood glucose levels drop too quickly following treatment.

      Headache, recurrence of vomiting, irritability, Glasgow Coma Scale score, inappropriate heart rate slowing, and rising blood pressure are the most common causes of death in paediatric DKA, and children should be monitored for the symptoms mentioned above. To prevent this from developing,  s low osmolarity normalization, attention to glucose and salt levels, as well as hydration over 48 hours, is necessary. 

    • This question is part of the following fields:

      • Musculoskeletal Pharmacology
      • Pharmacology
      153.7
      Seconds
  • Question 22 - A 20-year-old asthmatic patient's symptoms is deteriorating and patient is moved to the...

    Incorrect

    • A 20-year-old asthmatic patient's symptoms is deteriorating and patient is moved to the resuscitation area of the Emergency Department. A loading dose of IV aminophylline is administered and her symptoms begin to improve. You are asked to check her theophylline levels after an appropriate time period.

      How long should you wait before taking her blood sample be taken?

      Your Answer:

      Correct Answer: 4-6 hours

      Explanation:

      Plasma theophylline concentration is usually measured five days after starting oral treatment and three days after each dose adjustment.

      A blood sample to check theophylline concentration should usually be taken after 4-6 hours if an IV dose of aminophylline was given.

    • This question is part of the following fields:

      • Pharmacology
      • Respiratory Pharmacology
      0
      Seconds
  • Question 23 - Which of the following comprises a negative feedback mechanism? ...

    Incorrect

    • Which of the following comprises a negative feedback mechanism?

      Your Answer:

      Correct Answer: Detectors, comparators, a variable set point and effectors

      Explanation:

      Negative feedback loops, also known as inhibitory loops, play a crucial role in controlling human health. It is a self-regulating mechanism of some sort.

      A negative feedback system is made up of three main components: a detector (often neural receptor cells) that measures the variable in question and provides input to the comparator; a comparator (usually a neural assembly in the central nervous system) that receives input from the detector, compares the variable to the variable set point, and determines whether or not a response is required.

      The comparator activates an effector (typically muscular or glandular tissue) to conduct the appropriate reaction to return the variable to its set point.

    • This question is part of the following fields:

      • Basic Cellular
      • Physiology
      0
      Seconds
  • Question 24 - In patients requiring oxygen, who are at risk of hypercapnic respiratory failure, oxygen...

    Incorrect

    • In patients requiring oxygen, who are at risk of hypercapnic respiratory failure, oxygen saturations should be maintained at:

      Your Answer:

      Correct Answer: 88 - 92%

      Explanation:

      A lower target of 88 – 92% oxygen saturation is indicated for patients at risk of hypercapnic respiratory failure e.g. patients with COPD. Until blood gases can be measured, initial oxygen should be given using a controlled concentration of 28% or less, titrated towards the SpO2 of 88 – 92%. The aim is to provide the patient with enough oxygen to achieve an acceptable arterial oxygen tension without worsening carbon dioxide retention and respiratory acidosis.

    • This question is part of the following fields:

      • Pharmacology
      • Respiratory
      0
      Seconds
  • Question 25 - Antidiuretic hormone (ADH) levels are found to be increased in a young lady with...

    Incorrect

    • Antidiuretic hormone (ADH) levels are found to be increased in a young lady with unexplained hyponatraemia.

      In a healthy patient under normal circumstances, in which of the following conditions would ADH not be released?

      Your Answer:

      Correct Answer: Increased alcohol intake

      Explanation:

      Antidiuretic hormone (ADH) is produced in the hypothalamus’s supraoptic nucleus and then released into the blood via axonal projections from the hypothalamus to the posterior pituitary.

      It is carried down axonal extensions from the hypothalamus (the neurohypophysial capillaries) to the posterior pituitary, where it is kept until it is released, after being synthesized in the hypothalamus.
      The secretion of ADH from the posterior pituitary is regulated by numerous mechanisms:
      Increased plasma osmolality: Osmoreceptors in the hypothalamus detect an increase in osmolality and trigger ADH release.

      Hypovolaemia causes a drop in atrial pressure, which stretch receptors in the atrial walls and big veins detect (cardiopulmonary baroreceptors). ADH release is generally inhibited by atrial receptor firing, but when the atrial receptors are stretched, the firing reduces and ADH release is promoted.

      Hypotension causes baroreceptor firing to diminish, resulting in increased sympathetic activity and ADH release.
      An increase in angiotensin II stimulates angiotensin II receptors in the hypothalamus, causing ADH production to increase.

      Nicotine, Sleep, Fright, and Exercise are some of the other elements that might cause ADH to be released.
      Alcohol (which partly explains the diuretic impact of alcohol) and elevated levels of ANP/BNP limit ADH release.

    • This question is part of the following fields:

      • Physiology
      • Renal Physiology
      0
      Seconds
  • Question 26 - A 17-year-old male patient diagnosed with cystic fibrosis is experiencing shortness of breath,...

    Incorrect

    • A 17-year-old male patient diagnosed with cystic fibrosis is experiencing shortness of breath, coughing, and flu-like symptoms. His X-ray results shows atelectasis, or collapsed lung, specifically in his lower right lung. All of the following statements are true regarding collapsed lungs, except for which one.

      Your Answer:

      Correct Answer: Atelectasis is an example of a perfusion defect

      Explanation:

      Atelectasis is a complete or partial collapse of the lung. It occurs when the alveoli deflate or are filled with alveolar fluid. It is considered a ventilation defect of the alveoli due to cystic fibrosis. It is not a perfusion defect. A perfusion defect will produce pathological dead space in which the lung alveoli are ventilated adequately but are not perfused, and there is no gas exchange. While with atelectasis, the alveoli remain perfused. However, there is impaired oxygen delivery and intrapulmonary shunting of blood will be present in the collapsed area. Since there is no exchange of gas at the capillary-alveolar interface of the collapsed segments, the pulmonary capillary blood will have similar PO2 and PCO2.

    • This question is part of the following fields:

      • Physiology
      • Respiratory Physiology
      0
      Seconds
  • Question 27 - All of the following single clinical risk groups is considered eligible to receive...

    Incorrect

    • All of the following single clinical risk groups is considered eligible to receive the seasonal influenza vaccination, except:

      Your Answer:

      Correct Answer: Patients with hypertension

      Explanation:

      The following is the list of all the health and age factors that are known to increase a person’s risk of getting serious complications from flu:
      – Adults 65 years and older
      – Children younger than 2 years old
      – Asthma
      – Neurological and neurodevelopmental conditions
      – Blood disorders (such as sickle cell disease)
      – Chronic lung disease (such as chronic obstructive pulmonary disease [COPD] and cystic fibrosis)
      – Endocrine disorders (such as diabetes mellitus)
      – Heart disease (such as congenital heart disease, congestive heart failure and coronary artery disease)
      – Kidney diseases
      – Liver disorders
      – Metabolic disorders (such as inherited metabolic disorders and mitochondrial disorders)
      – People who are obese with a body mass index [BMI] of 40 or higher
      – People younger than 19 years old on long-term aspirin- or salicylate-containing medications.
      – People with a weakened immune system due to disease (such as people with HIV or AIDS, or some cancers such as leukaemia) or medications (such as those receiving chemotherapy or radiation treatment for cancer, or persons with chronic conditions requiring chronic corticosteroids or other drugs that suppress the immune system)
      – People who have had a stroke
      – Pregnant people and people up to 2 weeks after the end of pregnancy
      – People who live in nursing homes and other long-term care facilities

    • This question is part of the following fields:

      • Microbiology
      • Principles Of Microbiology
      0
      Seconds
  • Question 28 - A patient suffers an injury to the nerve that innervates piriformis.
    The piriformis muscle...

    Incorrect

    • A patient suffers an injury to the nerve that innervates piriformis.
      The piriformis muscle is innervated by which of the following nerves? Select ONE answer only.

      Your Answer:

      Correct Answer: Nerve to piriformis

      Explanation:

      Piriformis is innervated by the nerve to piriformis, which is a direct branch from the sacral plexus (S1 and S2).

    • This question is part of the following fields:

      • Anatomy
      • Lower Limb
      0
      Seconds
  • Question 29 - Antinuclear antibodies (ANAs) also referred to as anti-nuclear factors (ANFs) are autoantibodies that...

    Incorrect

    • Antinuclear antibodies (ANAs) also referred to as anti-nuclear factors (ANFs) are autoantibodies that bind to contents of the cell nucleus.

      Which ONE of these statements about ANAs is true?

      Your Answer:

      Correct Answer: They can be of any immunoglobulin class

      Explanation:

      Anti-nuclear antibodies(ANAs) also referred to as anti-nuclear factors (ANFs) are autoantibodies that bind to contents of the cell nucleus. They can be of any immunoglobulin class.

      CREST syndrome is usually associated with anti-centromere antibodies.

      ELISA testing is cheaper but not the most accurate means of testing for ANAs. Indirect immunofluorescence testing is the most reliable.

      Nucleolar staining is suggestive of scleroderma, while homogenous staining is suggestive of lupus.

      Anti-dsDNA antibodies are found in 80 – 90% of patients with SLE

    • This question is part of the following fields:

      • General Pathology
      • Pathology
      0
      Seconds
  • Question 30 - You are taking care of a 55-year-old male patient who is a weightlifter....

    Incorrect

    • You are taking care of a 55-year-old male patient who is a weightlifter. He is suspected of having a direct inguinal hernia. Where would this hernia appear?

      Your Answer:

      Correct Answer: Medial to the inferior epigastric artery

      Explanation:

      A direct inguinal hernia is a form of groin hernia that occurs when abdominal viscera protrude through a weakness in the posterior wall of the inguinal canal, notably through Hesselbach’s triangle, medial to the inferior epigastric veins.

    • This question is part of the following fields:

      • Abdomen
      • Anatomy
      0
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Infections (2/2) 100%
Pharmacology (3/5) 60%
Central Nervous System (0/1) 0%
Cardiovascular Pharmacology (1/1) 100%
Anatomy (2/6) 33%
Thorax (1/2) 50%
Microbiology (2/3) 67%
Pathogens (1/1) 100%
Specific Pathogen Groups (1/2) 50%
Lower Limb (1/2) 50%
General Pathology (0/1) 0%
Pathology (1/2) 50%
Gastrointestinal (1/2) 50%
Physiology (2/5) 40%
Endocrine Physiology (0/1) 0%
Inflammatory Responses (1/1) 100%
Abdomen And Pelvis (0/1) 0%
Basic Cellular (1/2) 50%
Cranial Nerve Lesions (0/1) 0%
Musculoskeletal Pharmacology (0/1) 0%
Passmed