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  • Question 1 - In a knockout mouse model the process used to combine the new DNA...

    Incorrect

    • In a knockout mouse model the process used to combine the new DNA sequence and the stem cells is known as:

      Your Answer: Chimerisation

      Correct Answer: Insertion

      Explanation:

      Chimerisation is also known as the formation of recombinant DNA. When a foreign DNA sequence is inserted into a plasmid or other DNA sequence, this process is known as insertion.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      26.5
      Seconds

  • Question 2 - What is the protective hexametric sequence at the ends of chromosomes called? ...

    Correct

    • What is the protective hexametric sequence at the ends of chromosomes called?

      Your Answer: Telomere

      Explanation:

      Telomeres are non coding DNA plus proteins that are found at the end of the linear chromosomes. They maintain the integrity of the chromosomes and prevent their shortening.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      64.7
      Seconds

  • Question 3 - Which of the following is true for P53: ...

    Incorrect

    • Which of the following is true for P53:

      Your Answer: Induction will induce necrosis in cancerous cells

      Correct Answer: It is induced by ‘broken’ DNA

      Explanation:

      P53 gene is activated as a result of damaged DNA and if that cannot be repaired then it activates apoptosis.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      18.5
      Seconds

  • Question 4 - Which of the following with regard to DNA mutations does not fit: ...

    Incorrect

    • Which of the following with regard to DNA mutations does not fit:

      Your Answer: Point mutations are the simplest type of change and may or may not cause a clinical disorder

      Correct Answer: All gene mutations cause clinical disease entities

      Explanation:

      All gene mutations do not cause a clinical manifestation of the disease, some gene mutations are silent mutations. They are present but do not cause any disease.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      24.4
      Seconds

  • Question 5 - Regarding DNA cloning and sequencing, all of the following are true, except: ...

    Incorrect

    • Regarding DNA cloning and sequencing, all of the following are true, except:

      Your Answer: In sequencing dideoxysequencing allows identification of exact nucleotide sequence

      Correct Answer: Yeast artificial chromosomes ( yacs) are vectors

      Explanation:

      Yeast chromosomes cannot be used as a vector. All the rest are true. Vectors can be bacteria, viruses and plasmids. DNA ligase binds the DNA fragment to the host DNA after insertion. Fluorescence can be used to visualize them.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      113.4
      Seconds

  • Question 6 - Consanguinity shows a strong association with which pattern of inheritance? ...

    Incorrect

    • Consanguinity shows a strong association with which pattern of inheritance?

      Your Answer: X linked dominant

      Correct Answer: Autosomal recessive

      Explanation:

      Consanguinity involves being from the same kinship as another person. It is a common feature of an autosomal recessive mode of inheritance

    • This question is part of the following fields:

      • Genetics
      • Medicine
      18.6
      Seconds

  • Question 7 - When during the cell cycle do the centrioles replicate? ...

    Incorrect

    • When during the cell cycle do the centrioles replicate?

      Your Answer: Mitosis

      Correct Answer: G1 phase

      Explanation:

      During G1 phase the cell will prepare for cell division. All the organelles will start to duplicate in this phase and the cell will begin to grow whilst proteins are also synthesized.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      43.6
      Seconds

  • Question 8 - Which of the following statements is true regarding chromosomes? ...

    Incorrect

    • Which of the following statements is true regarding chromosomes?

      Your Answer: The centromere divides the chromosome into the long (q) and short (p) arms

      Correct Answer: All are true

      Explanation:

      All of the above mentioned statements are true regarding chromosomes.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      22.6
      Seconds

  • Question 9 - In which phase do chromosomes in the nucleus become condensed into well-defined chromosomes?...

    Correct

    • In which phase do chromosomes in the nucleus become condensed into well-defined chromosomes?

      Your Answer: Metaphase

      Explanation:

      Prophase begins when the nucleus envelope disintegrates and the chromosomes start to condense. The chromosomes consist of two sister chromatids that are joined at a constriction known as centromere. When the cell reaches the metaphase the chromosomes are completely condensed and ready to align on the equatorial plate

    • This question is part of the following fields:

      • Genetics
      • Medicine
      18
      Seconds

  • Question 10 - During which phase of the cell cycle does transcription of DNA synthesis molecules...

    Correct

    • During which phase of the cell cycle does transcription of DNA synthesis molecules occur?

      Your Answer: S

      Explanation:

      DNA synthesis occurs in the S phase of the cell cycle. In the G1 phase the cell prepares to divide. In G2 the cellular organelles divide and in the M phase mitosis occur. In the G0 phase the cell becomes quiescent and does not divide further.

      Interphase is composed of G1 phase (cell growth), followed by S phase (DNA synthesis), followed by G2 phase (cell growth). At the end of interphase comes the mitotic phase, which is made up of mitosis and cytokinesis and leads to the formation of two daughter cells.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      45.5
      Seconds

  • Question 11 - Which of the following is an incorrect statement regarding the structure of DNA?...

    Correct

    • Which of the following is an incorrect statement regarding the structure of DNA?

      Your Answer: The two strands of DNA are held together by cysteine bonds.

      Explanation:

      The two strands of DNA are held together by hydrogen bonds formed between the nucleotide bases.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      45.7
      Seconds

  • Question 12 - Which of the following is false with regard to the following statement: Proto-...

    Incorrect

    • Which of the following is false with regard to the following statement: Proto- oncogenes can be transformed to oncogenes in the following ways.

      Your Answer: Chromosomal translocation

      Correct Answer: Inhibition of P53

      Explanation:

      Proto oncogenes cannot be transformed into oncogenes due to inhibition of P53 gene. There has to be a mutation in the proto oncogene. All the other options are true.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      49.2
      Seconds

  • Question 13 - Which of the following statements is true about chromosomes? ...

    Incorrect

    • Which of the following statements is true about chromosomes?

      Your Answer: Diploid human cells have 46 chromosomes, 23 inherited from each parent

      Correct Answer: All of the above

      Explanation:

      All of the above mentioned statements are true regarding chromosomes.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      54.1
      Seconds

  • Question 14 - In RFLP (restriction fragment length polymorphism), the DNA fragments are separated by length...

    Correct

    • In RFLP (restriction fragment length polymorphism), the DNA fragments are separated by length through a process known as:

      Your Answer: Agarose gel electrophoresis

      Explanation:

      Samples of DNA from individuals are broken into pieces by restriction enzymes and the fragments are separated according to their lengths via gel electrophoresis. Although now largely obsolete due to the rise of inexpensive DNA sequencing technologies, RFLP analysis was the first DNA profiling technique inexpensive enough to see widespread application.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      154.1
      Seconds

  • Question 15 - During which phase of the cell cycle does DNA synthesis occur? ...

    Correct

    • During which phase of the cell cycle does DNA synthesis occur?

      Your Answer: S

      Explanation:

      DNA synthesis occurs in the S phase of the cell cycle. In the G1 phase the cell prepares to divide. In G2 the cellular organelles divide and in the M phase mitosis occur. In the G0 phase the cell becomes quiescent and does not divide further

    • This question is part of the following fields:

      • Genetics
      • Medicine
      15.2
      Seconds

  • Question 16 - During which stage does the mitotic apparatus dissolute? ...

    Incorrect

    • During which stage does the mitotic apparatus dissolute?

      Your Answer: Metaphase

      Correct Answer: Telophase

      Explanation:

      In telophase the nuclear envelope along with the nucleolus will reappear. The daughter nuclei will enlarge as the chromosome will decondense again. Along with this, cytokinesis will occur. At the end of cytokinesis the daughter centrioles will move from the poles to the intercellular bridge where they will be disassembled and complete the separation of the daughter cells

    • This question is part of the following fields:

      • Genetics
      • Medicine
      12.2
      Seconds

  • Question 17 - Telomeres are best described as: ...

    Incorrect

    • Telomeres are best described as:

      Your Answer: The protein end portion of DNA protecting the DNA from damage

      Correct Answer: A repetitive DNA sequence at the end of a DNA molecule.

      Explanation:

      Telomeres are non-coding DNA consisting of repetitive nucleotide sequences plus proteins that are found at the end of the linear chromosomes. They maintain the integrity of the chromosomes and prevent their shortening.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      8.4
      Seconds

  • Question 18 - The length of DNA is generally measured in terms of the number of:...

    Correct

    • The length of DNA is generally measured in terms of the number of:

      Your Answer: Base pairs

      Explanation:

      As DNA is made up of nucleotides, its length is measured by the number of base pairs in the DNA molecules.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      9.1
      Seconds

  • Question 19 - Which of the following are true with regard to autosomal recessive disorders: ...

    Incorrect

    • Which of the following are true with regard to autosomal recessive disorders:

      Your Answer: The parents of the affected offspring are generally unaffected healthy carriers

      Correct Answer: All are true

      Explanation:

      All are true for autosomal recessive disorders.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      63
      Seconds

  • Question 20 - Male to male transmission is a key factor of which type of inheritance?...

    Incorrect

    • Male to male transmission is a key factor of which type of inheritance?

      Your Answer: X linked dominant

      Correct Answer: Autosomal dominant

      Explanation:

      Autosomal dominant type of inheritance can include both sexes in the same ratio. There is no skipping a generation and father to son transmission is common. The passing of the trait is sex independent.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      38.9
      Seconds

  • Question 21 - Critical shortening of Telomeres result in: ...

    Incorrect

    • Critical shortening of Telomeres result in:

      Your Answer: Inactivation of p53 and prb and cell crisis

      Correct Answer: Activation of p53 and prb and cell crisis

      Explanation:

      Telomeres are repetitive nucleotide sequences at the ends of chromosomes that protect them from deterioration or from fusion with neighboring chromosomes. Each time a cell divides, its telomeres shorten. When they become critically short, they can no longer protect the chromosome ends, triggering a DNA damage response.

      This response leads to the activation of tumor suppressor proteins p53 and pRb (retinoblastoma protein). Activated p53 can induce cell cycle arrest, allowing time for DNA repair or triggering apoptosis if the damage is irreparable. Similarly, pRb helps regulate cell cycle progression and can halt the cell cycle to prevent the proliferation of cells with damaged DNA.

      As a result, the cell enters a state of crisis, characterized by widespread cell death and genomic instability, which ultimately prevents the propagation of cells with critically shortened telomeres.

      Therefore, the correct answer is:

      Activation of p53 and pRb and cell crisis

    • This question is part of the following fields:

      • Genetics
      • Medicine
      90.6
      Seconds

  • Question 22 - During which phase of meiosis does exchange of genetic material occur accounting for...

    Incorrect

    • During which phase of meiosis does exchange of genetic material occur accounting for genetic diversity between individuals:

      Your Answer:

      Correct Answer: Prophase 1

      Explanation:

      Prophase 1 has been divided into five different stages ( laptotene, zygotene, pachytene, diplotene ans diakinesis). In prophase 1 chromosomes are going to condense to become visible, each chromosome will contain two chromatids that are joined at the centromere. the nucleolus and nuclear envelope are going to disintegrate. the homologous chromosomes will form tetrad and crossing over will occur between the chromosomes (random exchange of genes), the point of exchange is known as the chiasmata, this increases genetic diversity.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 23 - Regarding Southern Blotting and DNA probes, which answer is FALSE ...

    Incorrect

    • Regarding Southern Blotting and DNA probes, which answer is FALSE

      Your Answer:

      Correct Answer: RNA fragments are separated by gel electrophoresis and transferred onto membrane sheets in southern blotting

      Explanation:

      Restriction enzymes always cut at different positions. There are different restriction endonucleases for different nucleotide sequences.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 24 - The length of DNA is generally measured in terms of number of: ...

    Incorrect

    • The length of DNA is generally measured in terms of number of:

      Your Answer:

      Correct Answer: Base pairs

      Explanation:

      As DNA is made up of nucleotides, its length is measured by the number of base pairs in the DNA molecules.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 25 - In most somatic cells telomeres progressively shorten as: ...

    Incorrect

    • In most somatic cells telomeres progressively shorten as:

      Your Answer:

      Correct Answer: The cell divides

      Explanation:

      Telomere length shortens with age. Progressive shortening of telomeres leads to senescence, apoptosis, or oncogenic transformation of somatic cells, affecting the health and lifespan of an individual. Telomeres prevent the chromosomes from shortening and prevent the coding portion of the DNA from being lost, thus allowing the cell to replicate indefinitely. During replication telomeres may be lost resulting in cell death.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 26 - In Restriction Fragment Length Polymorphism (RFLP), the DNA fragments are separated by length through...

    Incorrect

    • In Restriction Fragment Length Polymorphism (RFLP), the DNA fragments are separated by length through a process known as:

      Your Answer:

      Correct Answer: Gel electrophoresis

      Explanation:

      Samples of DNA from individuals are broken into pieces by restriction enzymes and the fragments are separated according to their lengths via gel electrophoresis. Although now largely obsolete due to the rise of inexpensive DNA sequencing technologies, RFLP analysis was the first DNA profiling technique inexpensive enough to see widespread application.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 27 - The process by which DNA fragments are separated by gel and transferred onto...

    Incorrect

    • The process by which DNA fragments are separated by gel and transferred onto a membrane sheet is called:

      Your Answer:

      Correct Answer: Southern blotting

      Explanation:

      A Southern blot is a method used in molecular biology for detection of a specific DNA sequence in DNA samples. Southern blotting combines transfer of electrophoresis-separated DNA fragments to a filter membrane and subsequent fragment detection by probe hybridization. The other forms of blotting involve the use of RNA and proteins.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 28 - The chromosomes that principally encode for proteins or RNA molecules involved in mitochondrial...

    Incorrect

    • The chromosomes that principally encode for proteins or RNA molecules involved in mitochondrial function are found:

      Your Answer:

      Correct Answer: In the nucleus of each diploid cell

      Explanation:

      While mitochondria have their own small circular DNA (mtDNA) that encodes some of the proteins and RNAs required for mitochondrial function, the majority of proteins involved in mitochondrial function are encoded by nuclear DNA. These nuclear genes are transcribed in the nucleus and then translated into proteins in the cytoplasm. The proteins are subsequently imported into the mitochondria.

      Therefore, the correct answer is:

      • In the nucleus of each diploid cell

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 29 - Restriction Enzymes... ...

    Incorrect

    • Restriction Enzymes...

      Your Answer:

      Correct Answer: Cut DNA sequences at specific sites

      Explanation:

      Restriction endonucleases are enzymes that recognise short sequences of double stranded DNA and cut them at specific nucleotide points or sequences. These sequences differ for different restriction endonucleases.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 30 - Which statement about X linked dominant disorders is FALSE? ...

    Incorrect

    • Which statement about X linked dominant disorders is FALSE?

      Your Answer:

      Correct Answer: Heterozygous females tend to have the disease more severely than affected males.

      Explanation:

      Women who have the affected X chromosome will be affected, but the severity will be less than that in males as they have a normal X chromosome to counter the effect of the mutated X chromosome. Affected males will pass on the defect to their daughters 100% of the time but not to their sons.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 31 - With regards to P53, which statement is NOT true? ...

    Incorrect

    • With regards to P53, which statement is NOT true?

      Your Answer:

      Correct Answer: P53 is a RNA binding protein

      Explanation:

      P53 is a tumour suppressor gene. It is not an RNA binding protein. It has been implicated in almost all tumours. It regulates the progression from G1 to the S phase of the cell cycle and is activated in response to damaged DNA.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 32 - Near the transcription site of a gene, the site at which RNA polymerase...

    Incorrect

    • Near the transcription site of a gene, the site at which RNA polymerase and its cofactors bind is known as the:

      Your Answer:

      Correct Answer: Promotor

      Explanation:

      Transcription will begin when the RNA polymerase II binds to the promotor. The promotor is a sequence of 25 nucleotides found upstream from the start site of transcription. This promotor sequence is known as the TATA box. Transcription factors also bond along with RNA polymerase to this site to form a complex. However some may bind to regulatory elements proximal to the promotor site.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 33 - In which phase do chromosomes in the nucleus become completely condensed into well-defined...

    Incorrect

    • In which phase do chromosomes in the nucleus become completely condensed into well-defined chromosomes?

      Your Answer:

      Correct Answer: Metaphase

      Explanation:

      Prophase begins when the nucleus envelope disintegrates and the chromosomes start to condense. The chromosomes consist of two sister chromatids that are joined at a constriction known as centromere. When the cell reaches the metaphase the chromosomes are completely condensed and ready to align on the equatorial plate

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 34 - In DNA cloning and sequencing, the bases in nucleotides chains are bound together...

    Incorrect

    • In DNA cloning and sequencing, the bases in nucleotides chains are bound together by:

      Your Answer:

      Correct Answer: Hydrogen bonding.

      Explanation:

      Nucleotides will always bind together via hydrogen bonds. There are two hydrogen bonds present between thymine and adenine and three hydrogen bonds present between guanine and cytosine.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 35 - Normal parents have a child with a recessive condition, Tay Sachs. The chance...

    Incorrect

    • Normal parents have a child with a recessive condition, Tay Sachs. The chance of them having a normal child is?

      Your Answer:

      Correct Answer: 75%

      Explanation:

      The chance for normal parents having a child with a recessive disease is 1:4 or 25%. As both the parents are heterozygous for this condition. They have a 3:4 chance of having a normal child or 75%.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 36 - Which statement is correct regarding mRNA? ...

    Incorrect

    • Which statement is correct regarding mRNA?

      Your Answer:

      Correct Answer: mRNAs are mainly found in the nucleus and cytoplasm of a cell.

      Explanation:

      mRNA is transcribed from DNA and is carried to the cytosol to be translated. Hence it is mainly found in the cytosol and the nucleus of a cell. It is single stranded and contains the base uracil instead of thymine.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 37 - Regarding Polymerase Chain Reaction, all are true except: ...

    Incorrect

    • Regarding Polymerase Chain Reaction, all are true except:

      Your Answer:

      Correct Answer: There is a linear rise of DNA copies during amplification.

      Explanation:

      All are true except there is a linear rise of DNA copies during amplification. There is an exponential rise in amplification of DNA.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 38 - What is the structure of nucleosomes? ...

    Incorrect

    • What is the structure of nucleosomes?

      Your Answer:

      Correct Answer: Strands of double strand DNA + histones

      Explanation:

      DNA is packed and condensed by binding to histone proteins. The double stranded DNA forms a complex with histone proteins which is called a nucleosome. There are 8 histone proteins contained in one core of nucleosome.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 39 - The telomerase is capable of adding several more repeats of telomeres at which...

    Incorrect

    • The telomerase is capable of adding several more repeats of telomeres at which end of the guanosine rich region.

      Your Answer:

      Correct Answer: 3rd end

      Explanation:

      Telomerase is a reverse transcriptase that uses the RNA template to synthesize DNA in the 5th-3rd direction resulting in extension of the 3rd end and then translocates it to the newly synthesized end. The GT rich strand is thus elongated.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 40 - Telomerase is active in all of the following cells, except: ...

    Incorrect

    • Telomerase is active in all of the following cells, except:

      Your Answer:

      Correct Answer: Certain liver cells

      Explanation:

      Telomerase is an enzyme that adds repetitive nucleotide sequences to the ends of chromosomes (telomeres), preventing their shortening during cell division. Telomerase activity is crucial for cells that divide frequently and need to maintain their telomere length for continued proliferation. These include:

      • Stem cells: They have high telomerase activity to maintain their long-term proliferative capacity.
      • Germ cells: These cells also have active telomerase to ensure the stability of genetic material across generations.
      • Certain white blood cells: Some immune cells, particularly those that need to proliferate in response to infection, show telomerase activity.
      • Certain cancer cells: Many cancer cells reactivate telomerase, which contributes to their uncontrolled growth and immortality.

      However, most somatic cells, including certain liver cells, do not exhibit significant telomerase activity. While some liver cells might show low levels of telomerase activity during regeneration, it is not generally active in normal, differentiated liver cells.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 41 - Under normal conditions (where n represents the number of chromosome pairs), just before...

    Incorrect

    • Under normal conditions (where n represents the number of chromosome pairs), just before mitosis begins, how many chromosomes are contained in the nucleus of each somatic cell:

      Your Answer:

      Correct Answer: 4n

      Explanation:

      In a normal somatic cell there are 2n chromosome but in a replicating cell just before mitosis the chromosomes duplicate but are still joined via the centrosome. Thus there are 4n chromosomes. After completion of mitosis the number goes back to 2n.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 42 - The enzyme responsible for Telomeres to maintain their length after cell division is...

    Incorrect

    • The enzyme responsible for Telomeres to maintain their length after cell division is called:

      Your Answer:

      Correct Answer: Telomerase reverse transcriptase

      Explanation:

      Telomeres are non-coding DNA consisting of repetitive nucleotide sequences plus proteins that are found at the end of the linear chromosomes. They maintain the integrity of the chromosomes and prevent their shortening.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 43 - When 2 nucleotide chains of DNA bind together, thymine is bound to: ...

    Incorrect

    • When 2 nucleotide chains of DNA bind together, thymine is bound to:

      Your Answer:

      Correct Answer: Adenine

      Explanation:

      As a general rule in the structure of DNA, thymine always binds to adenine with two hydrogen bonds, cytosine always binds to guanine with three hydrogen bonds and vice versa. However In the structure of RNA the only difference is that adenine binds to uracil instead of thymine. But thymine will always bind to adenine.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 44 - Defects in chromosomal structure (and examples) include those mentioned below except: ...

    Incorrect

    • Defects in chromosomal structure (and examples) include those mentioned below except:

      Your Answer:

      Correct Answer: Lyonization (x-linked disorders)

      Explanation:

      All are true except for A) Lyonization which is the inactivation of the X chromosomes in a female. It is not a chromosomal abnormality.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 45 - The process of DNA amplification and quantification is called: ...

    Incorrect

    • The process of DNA amplification and quantification is called:

      Your Answer:

      Correct Answer: PCR

      Explanation:

      PCR/polymerase chain reaction is a procedure carried out in a test tube that can be used on the smallest amount of DNA to amplify it, allowing for millions of copies of specific nucleotides to be made.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 46 - When one of the two copies of the autosomes has a mutation and...

    Incorrect

    • When one of the two copies of the autosomes has a mutation and the protein produced by the normal form of the gene cannot compensate. The affected individual has an:

      Your Answer:

      Correct Answer: Autosomal dominant disorder

      Explanation:

      An autosomal dominant trait will be expressed no matter the consequence. If one chromosome has a mutation the other will not be able to compensate for the mutation hence the protein formed will be mutated and will not function properly.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 47 - The process whereby DNA fragments are separated by size and charge is called:...

    Incorrect

    • The process whereby DNA fragments are separated by size and charge is called:

      Your Answer:

      Correct Answer: Gel electrophoresis

      Explanation:

      Fragments of DNA of varying length can be separated on the basis of their charge and their size by a process called gel electrophoresis. Because DNA contains negatively charged phosphate groups, it will migrate in an electric field toward the positive electrode. Shorter chains migrate more rapidly through the pores of the gel, and thus separation depends on length. DNA bands in the gel can be visualized by various techniques including staining with dyes and autoradiography.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 48 - The process by which RNA fragments are separated by gel electrophoresis and transferred...

    Incorrect

    • The process by which RNA fragments are separated by gel electrophoresis and transferred onto a membrane sheet is called:

      Your Answer:

      Correct Answer: Northern blotting

      Explanation:

      Blots of the gel can be made from using nitrocellulose paper. Northern blots are produced when a fragment of radioactive DNA hybridize with RNA on a nitrocellulose blot of a gel and southern blots are produced when DNA hybrize with DNA on a nitrocellulose blot of the gel.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 49 - Which statement is correct? ...

    Incorrect

    • Which statement is correct?

      Your Answer:

      Correct Answer: MtDNA principally encodes for proteins that are involved in oxidative phosphorylation for the production of ATP in the cell.

      Explanation:

      Mitochondria have no nucleus instead they contain their own free floating circular genome (MtDNA), which encodes 13 different subunits of proteins involved in oxidative phosphorylation. The remainder of the mitochondrial proteins are nuclear encoded, synthesized in the cytoplasm, and transported into the mitochondria.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

  • Question 50 - When during the cell cycle does DNA replication occur? ...

    Incorrect

    • When during the cell cycle does DNA replication occur?

      Your Answer:

      Correct Answer: S phase

      Explanation:

      The S phase is known as the synthesis phase. During this phase DNA will begin to replicated, as well as the synthesis of the centrosomes and associated proteins.

    • This question is part of the following fields:

      • Genetics
      • Medicine
      0
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Genetics (7/21) 33%
Medicine (7/21) 33%
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