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  • Question 1 - You see a patient in antenatal clinic who is concerned that she has...

    Correct

    • You see a patient in antenatal clinic who is concerned that she has never had chicken pox and may catch it during pregnancy. You check her Varicella status and she is non-immune. She asks you about vaccination. What type of vaccine is the varicella vaccine?

      Your Answer: Attenuated

      Explanation:

      Varicella is a live vaccine. The recent RCOG green top guidelines suggest vaccine can be considered postpartum or pre pregnancy but NOT whilst pregnant. In the non-immune pregnant woman they should be advised to avoid contact with people with chickenpox or shingles and to contact a healthcare professional promptly if exposed. If they have a significant exposure VZIG should be offered as soon as possible.

    • This question is part of the following fields:

      • Immunology
      7.7
      Seconds

  • Question 2 - Which immunoglobulin provides passive immunity to the neonate? ...

    Correct

    • Which immunoglobulin provides passive immunity to the neonate?

      Your Answer: IgG

      Explanation:

      Passive immunity to the neonate is provided by immunoglobulin G (IgG) since it can be transferred through the placenta from mother to the foetus.
      IgA is transferred from mothers to offspring through breast milk.
      IgM molecular structure is too big to be filtered through the placental vasculature to the foetus. IgM is the first Ig to be synthesised by the neonate

    • This question is part of the following fields:

      • Immunology
      3.2
      Seconds

  • Question 3 - Which Immunoglobulin (or antibody) is secreted in large amounts in breast milk? ...

    Correct

    • Which Immunoglobulin (or antibody) is secreted in large amounts in breast milk?

      Your Answer: IgA

      Explanation:

      When considering immunoglobulins in neonates. There are only a few key points you are likely to be tested on. 1. IgA is resistant to stomach acid and found in large amounts in breast milk. 2. IgG is the only Ig that can cross the placenta so is key for passive neonatal immunity 3. When the neonate starts synthesising its own Ig it is IgM that is produced first.

    • This question is part of the following fields:

      • Immunology
      7
      Seconds

  • Question 4 - Which of the following will require Anti-D administration post partum? ...

    Correct

    • Which of the following will require Anti-D administration post partum?

      Your Answer: Rhesus negative mother, non-sensitised, fetal cord blood Rh positive

      Explanation:

      Rhesus positive mothers should not get anti-D. They have Rhesus antigens and the anti-D would result in maternal blood being bound and removed from her circulation. The danger is to children born to mothers who are rhesus negative. As the mother may develop antibodies against Rhesus positive fetal blood. Therefore if the baby is Rhesus negative then there is no risk of alloimmunisation (sensitisation)

    • This question is part of the following fields:

      • Immunology
      10.6
      Seconds

  • Question 5 - Rhesus D immunoglobin treatment utilises what class of antibody? ...

    Correct

    • Rhesus D immunoglobin treatment utilises what class of antibody?

      Your Answer: IgG

      Explanation:

      It utilizes the IgG class of the antibody.

    • This question is part of the following fields:

      • Immunology
      12.6
      Seconds

  • Question 6 - Which of the following is a tumour marker for ovarian cancer? ...

    Correct

    • Which of the following is a tumour marker for ovarian cancer?

      Your Answer: Ca 125

      Explanation:

      CA-125 is the tumour marker specific for ovarian carcinoma.

    • This question is part of the following fields:

      • Immunology
      3.5
      Seconds

  • Question 7 - Macrophages are derived from what type of white blood cell? ...

    Correct

    • Macrophages are derived from what type of white blood cell?

      Your Answer: Monocytes

      Explanation:

      Macrophages are derived from monocytes. When monocytes come across a pathogen they differentiate into macrophages for phagocytosis to occur.

    • This question is part of the following fields:

      • Immunology
      2.5
      Seconds

  • Question 8 - At what stage of gestation does maternal immunoglobulin G transfer to the foetus...

    Correct

    • At what stage of gestation does maternal immunoglobulin G transfer to the foetus start?

      Your Answer: 12 weeks

      Explanation:

      Transportation of the maternal IgG through the placenta starts around the 12 week of gestation.

    • This question is part of the following fields:

      • Immunology
      5.3
      Seconds

  • Question 9 - At what stage of gestation does fetal immunoglobulin M production begin? ...

    Correct

    • At what stage of gestation does fetal immunoglobulin M production begin?

      Your Answer: Week 10

      Explanation:

      Maternofetal IgG transfer starts around week 12. Fetal production IgM starts around week 10 to 11.

    • This question is part of the following fields:

      • Immunology
      7
      Seconds

  • Question 10 - The Mantoux test utilises what type of hypersensitivity reaction? ...

    Incorrect

    • The Mantoux test utilises what type of hypersensitivity reaction?

      Your Answer:

      Correct Answer: Type IV

      Explanation:

      The Mantoux test is based on type IV hypersensitivity reaction.

    • This question is part of the following fields:

      • Immunology
      0
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Immunology (9/9) 100%
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