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  • Question 1 - A typical sleep cycle from stage 1 to the end of REM sleep...

    Incorrect

    • A typical sleep cycle from stage 1 to the end of REM sleep in a normal adult is approximately how long?

      Your Answer: 120 min

      Correct Answer: 90 min

      Explanation:

      A single sleep cycle has stages 1, 2, 3, 4 and REM (Rapid eye movement). These stages progress cyclically from 1 through to REM and then begin again with stage 1. A complete sleep cycle takes an average of 90-110 minutes, with each stage lasting between 5 to 15 minutes.

    • This question is part of the following fields:

      • Neuro-anatomy
      17
      Seconds

  • Question 2 - Which statement is incorrect regarding nociceptor C fibers… ...

    Incorrect

    • Which statement is incorrect regarding nociceptor C fibers…

      Your Answer: Activity in the fiber activates a slow pain response

      Correct Answer: They are thinly myelinated

      Explanation:

      Group C nerve fibers are unmyelinated and have a small diameter, which means they conduct impulses at a low velocity. They carry sensory information and nociception.

    • This question is part of the following fields:

      • Neuro-anatomy
      16.7
      Seconds

  • Question 3 - The majority striatal neurons, called medium spiny neurons, utilizes which neurotransmitter? ...

    Incorrect

    • The majority striatal neurons, called medium spiny neurons, utilizes which neurotransmitter?

      Your Answer: Dopamine

      Correct Answer: GABA

      Explanation:

      Medium spiny neurons are inhibitory neurons which use GABA (gamma-aminobutyric acid) which exerts inhibitory actions. These cells represent 95% of neurones within the human striatum found in basal ganglia.

    • This question is part of the following fields:

      • Neuro-anatomy
      21.8
      Seconds

  • Question 4 - In which cell would you find a Nissl body? ...

    Correct

    • In which cell would you find a Nissl body?

      Your Answer: Bipolar neuron

      Explanation:

      Nissl bodies are the structures of protein synthesis in neurones. They are granular bodies of Rough Endoplasmic Reticulum and ribosomes. Astrocytes, Microglia, Schwann cell, oligodendrocytes are collectively known as glia or supporting cells of the nervous system.

    • This question is part of the following fields:

      • Neuro-anatomy
      40.9
      Seconds

  • Question 5 - Afferent A δ fibers from nociceptors terminate primarily on neurons in which lamina:...

    Incorrect

    • Afferent A δ fibers from nociceptors terminate primarily on neurons in which lamina:

      Your Answer: III and IV

      Correct Answer: I and V

      Explanation:

      Nociceptors are receptors of pain sensation. There are 2 primary afferent/sensory pain fibers which transmit impulses from the receptor to the CNS, specifically to the dorsal horn of the spinal cord. The two fibers are A δ and C fibers. The dorsal horn of the spinal cord is the relay centre for sensory information converging from the periphery. Grey matter of the dorsal horn is subdivided in to laminae based on cytoarchitecture. C fibers terminate in lamina II the substantia gelatinosa. A δ fibers terminate primarily in lamina I but some project more deeply to terminate in lamina V.

    • This question is part of the following fields:

      • Neuro-anatomy
      54.8
      Seconds

  • Question 6 - The tectum as part of the Midbrain contains which structure important in visual...

    Correct

    • The tectum as part of the Midbrain contains which structure important in visual reflexes.

      Your Answer: Superior colliculus

      Explanation:

      The tectum is a part of the midbrain, specifically, the dorsal part of the midbrain. The tectum consists of the superior and inferior colliculi. The superior colliculus is involved in preliminary visual processing and control of eye movement.

    • This question is part of the following fields:

      • Neuro-anatomy
      8.4
      Seconds

  • Question 7 - Which of the following forms the language areas of the cerebral cortex? ...

    Correct

    • Which of the following forms the language areas of the cerebral cortex?

      Your Answer: All of the above

      Explanation:

      Broca’s area, Wernicke’s area, the submarginal sulcus and the angular gyrus all form the language areas of the cerebral cortex.

    • This question is part of the following fields:

      • Neuro-anatomy
      6.6
      Seconds

  • Question 8 - What happens first during depolarisation of the membrane potential? ...

    Incorrect

    • What happens first during depolarisation of the membrane potential?

      Your Answer: Gated Na channels open allowing the efflux of Na

      Correct Answer: Gated Na channels open allowing the influx of Na

      Explanation:

      Generation of an action potential in response to a stimulus is a result of a previously maintained resting membrane potential (RMP). Generation of resting membrane potential is mediated mainly by potassium ions. Several membrane proteins maintain RMP by transport of ions in and out of cell. Na+/K+ ATPase pump maintains a concentration gradient of Na+ and K+ ions. Na+ concentration in extracellular fluid is higher compared to intracellular fluid and K+ ion concentration is higher intracellularly. Generation of an action potential facilitates opening of Na+ ion channels which allow for Na+ to diffuse inside the cell according to the concentration gradient.

    • This question is part of the following fields:

      • Neuro-anatomy
      140.6
      Seconds

  • Question 9 - Visceral afferent fibers are found in the following areas except the…? ...

    Correct

    • Visceral afferent fibers are found in the following areas except the…?

      Your Answer: Trigeminal nerve

      Explanation:

      The general visceral afferent (GVA) fibers carry impulses from viscera to the central nervous system. The cranial nerves that contain GVA fibers include the facial nerve, the glossopharyngeal nerve and the vagus nerve

    • This question is part of the following fields:

      • Neuro-anatomy
      35.1
      Seconds

  • Question 10 - Corticospinal tracts are located in the ___ of the white matter. ...

    Correct

    • Corticospinal tracts are located in the ___ of the white matter.

      Your Answer: Anterior and lateral funiculi

      Explanation:

      The corticospinal tract is a descending or a motor tract which projects nerve fibers from the cortex of the cerebrum down to different levels of the spinal cord. The descending corticospinal tract descends from the origin, through the corona radiata, posterior half of the lateral ventricle, and enters the midbrain through the cerebral peduncle. In the medulla they form the medullary pyramids on either side of midline as lateral and anterior fibers.

    • This question is part of the following fields:

      • Neuro-anatomy
      65.5
      Seconds

  • Question 11 - Which enzyme is responsible for the removal of acetylcholine from the synapse? ...

    Correct

    • Which enzyme is responsible for the removal of acetylcholine from the synapse?

      Your Answer: Acetylcholinesterase

      Explanation:

      Acetylcholinesterase is the enzyme that is responsible for breaking down acetylcholine into choline and acetate. Both of these molecules are transported back to the presynaptic neuron to be synthesized again. This enzyme is attached to the collagen fibers of the basement membrane in the synaptic cleft.

    • This question is part of the following fields:

      • Neuro-anatomy
      6.4
      Seconds

  • Question 12 - The majority of corticospinal tract fibers decussate in the: ...

    Correct

    • The majority of corticospinal tract fibers decussate in the:

      Your Answer: Medulla

      Explanation:

      The corticospinal tract is a descending motor path way that begins in the cerebral cortex and decussates in the pyramids of the medulla.

    • This question is part of the following fields:

      • Neuro-anatomy
      7.9
      Seconds

  • Question 13 - Visual pathways - Choose the true statement: ...

    Incorrect

    • Visual pathways - Choose the true statement:

      Your Answer: The temporal fibers from each optic nerve decussate at the optic chiasm

      Correct Answer: The lateral geniculate nucleus, magnocellular & parvocellular pathways project to the primary visual cortex

      Explanation:

      The optic chiasm is made by the decussation of optic fibers on the nasal side. The magnocellular pathway carries signals for detection of movement. The parvocellular pathway carries cells for detection of shape, size, colour and clarity. The lateral geniculate nucleus (LGN) is the relay centre in the thalamus for he visual pathway. It has layers of magnocellular cells and parvocellular cells that are interleaved with layers of koniocellular cells. The LGN is the main central connection for the optic nerve to the occipital lobe, particularly the primary visual cortex.

    • This question is part of the following fields:

      • Neuro-anatomy
      54
      Seconds

  • Question 14 - Where is the aqueous humor normally reabsorbed? ...

    Incorrect

    • Where is the aqueous humor normally reabsorbed?

      Your Answer: Ciliary body

      Correct Answer: Canal of schlemm

      Explanation:

      Aqueous humor is a clear protein free fluid secreted by the ciliary body, it travels to the anterior chamber through the pupil and is absorbed through a network of trabeculae into the canal of schlemm

    • This question is part of the following fields:

      • Neuro-anatomy
      4.9
      Seconds

  • Question 15 - The following is true about the carotid arterial supply to the brain: ...

    Correct

    • The following is true about the carotid arterial supply to the brain:

      Your Answer: Following carotid occlusion, precapillary anastomoses are unable to prevent infarction

      Explanation:

      The brain has two sources of blood supply; the internal carotid arteries which are the anterior segment or the main artery that supplies the anterior portion of the brain, and the vertebral arteries which is the posterior segment which supplies the posterior portion of the brain. The internal carotid arteries branch and form two major arteries anterior and middle cerebral arteries. The right and left vertebral arteries fuse together at the level of the pons on the anterior surface of the brainstem to form the midline basilar artery. The basilar artery joins the blood supply from the internal carotids in an arterial ring at the base of the brain called the circle of Willis. The anterior and posterior communicating arteries conjoin the two major sources of cerebral vascular supply via the circle of Willis improving the chances of any region of the brain continuing to receive blood if one of the major arteries becomes occluded.

    • This question is part of the following fields:

      • Neuro-anatomy
      70.8
      Seconds

  • Question 16 - Choose the correct answer: fibers in the superior cerebellar peduncle: ...

    Correct

    • Choose the correct answer: fibers in the superior cerebellar peduncle:

      Your Answer: Are mainly ventral spinocerebellar tracts from the cerebellar nuclei to the thalamus and red nucleus

      Explanation:

      There are three cerebellar peduncles with different connections and functions. The three are mainly, superior, middle and inferior. The superior cerebellar peduncle is also known as the “Brachium conjunctivum”. It predominantly contains efferent fibers from the cerebellar nuclei, as well as some afferents from the spinocerebellar tract. The efferent pathways include cerebellorubral, dentatothalamic, and fastigioreticular fibers. These are tracts projecting from the deep cerebellar nuclei to the thalamus and red nucleus. The middle cerebellar peduncle connects to the pontine nucleus and the dorsal spinocerebellar tracts run through the superior cerebellar peduncle.

    • This question is part of the following fields:

      • Neuro-anatomy
      31.1
      Seconds

  • Question 17 - Where do the spinothalamic axons decussate? ...

    Incorrect

    • Where do the spinothalamic axons decussate?

      Your Answer: Medulla

      Correct Answer: Spinal cord

      Explanation:

      The second order neurons from the spinothalamic tract cross obliquely to the opposite side in the anterior grey and white commissure within one segment of the spinal cord.

    • This question is part of the following fields:

      • Neuro-anatomy
      15.8
      Seconds

  • Question 18 - In the basal ganglia, the Lentiform nucleus is formed by which two nuclei?...

    Correct

    • In the basal ganglia, the Lentiform nucleus is formed by which two nuclei?

      Your Answer: Putamen and Globus pallidus

      Explanation:

      The Basal Ganglia are composed of the following structures: Caudate, putamen, Globus pallidus, subthalamic nucleus and substantia nigra. The lentiform nucleus comprises of the putamen and the Globus pallidus.

    • This question is part of the following fields:

      • Neuro-anatomy
      12.6
      Seconds

  • Question 19 - The spinothalamic tracts are particularly concerned with… ...

    Correct

    • The spinothalamic tracts are particularly concerned with…

      Your Answer: Pain and temperature sensations

      Explanation:

      The spinothalamic tracts are ascending or sensory tracts, responsible for transmission of pain and temperature.

    • This question is part of the following fields:

      • Neuro-anatomy
      19.8
      Seconds

  • Question 20 - An example of cholinergic autonomic neurons are: ...

    Correct

    • An example of cholinergic autonomic neurons are:

      Your Answer: Sympathetic postganglionic neurons that innervate sweat glands.

      Explanation:

      All preganglionic neurons in both the sympathetic and parasympathetic nervous system secrete acetylcholine. The postganglionic neurotransmitter of the parasympathetic nervous system in all neurons is acetylcholine. Postganglionic fibers of the sympathetic nervous system mainly secrete Noradrenalin and Adrenalin but at sweat glands and erector pili muscles the postganglionic neurotransmitter is acetylcholine.

    • This question is part of the following fields:

      • Neuro-anatomy
      16.9
      Seconds

  • Question 21 - Which dorsal (sensory) root is responsible for umbilical area sensation? ...

    Correct

    • Which dorsal (sensory) root is responsible for umbilical area sensation?

      Your Answer: T10

      Explanation:

      The area of skin supplied by one nerve is called a dermatome. T10 supplies sensory neurons to the area of the umbilicus. C3 and C4 supply the neck and the shoulder, T4 supplies the dermatome at the level of the nipple, S3 supplies the inguinal region and L5 supplies the lateral aspect of the leg and the medical aspect of the dorsum of the feet plus the first 3 toes.

    • This question is part of the following fields:

      • Neuro-anatomy
      69.9
      Seconds

  • Question 22 - Cranial nerves VI, VII, VIII enter/exit the base of the brain at the:...

    Correct

    • Cranial nerves VI, VII, VIII enter/exit the base of the brain at the:

      Your Answer: Ponto-medullary junction

      Explanation:

      Cranial nerves III, IV and V exit from the pons, VI, VII, VIII exit from the pontomedullary junction and cranial nerve IX, X, XI, XII exit from the medulla.

    • This question is part of the following fields:

      • Neuro-anatomy
      18.3
      Seconds

  • Question 23 - The nucleus tractus solitaries is medullary nucleus that processes the following inputs except:...

    Correct

    • The nucleus tractus solitaries is medullary nucleus that processes the following inputs except:

      Your Answer: Sensory input from the semi-circular canal (CN VIII)

      Explanation:

      Located in the brain stem is a series of purely sensory nuclei known as tractus solitaries. Inputs of the nucleus tractus solitaries include:
      Taste information from the facial nerve (anterior 2/3 of the tongue), glossopharyngeal nerve (posterior 1/3) and vagus nerve (small area on the epiglottis).
      Sensory information from the ear (auricular branch of the vagus nerve).
      Chemoreceptors and mechanoreceptors of the general visceral afferent pathway (GVA) in the carotid body via glossopharyngeal nerve, aortic bodies, and the sinoatrial node, via the vagus nerve.
      Chemically and mechanically sensitive neurons of the general visceral afferent pathway (GVA) with endings located in the heart, lungs, airways, gastrointestinal system, pharynx, and liver via the glossopharyngeal and vagus nerves.

    • This question is part of the following fields:

      • Neuro-anatomy
      20.4
      Seconds

  • Question 24 - What is found in the posterior cavity of the eye? ...

    Correct

    • What is found in the posterior cavity of the eye?

      Your Answer: Vitreous humor

      Explanation:

      The eye ball contains an anterior cavity and a posterior cavity. The anterior cavity once again is divided into the anterior chamber and posterior chamber. The anterior cavity is filled with aqueous humor whereas the posterior cavity contains vitreous humor.

    • This question is part of the following fields:

      • Neuro-anatomy
      19.4
      Seconds

  • Question 25 - The brainstem contains which of the following structures? ...

    Correct

    • The brainstem contains which of the following structures?

      Your Answer: The midbrain, pons and medulla

      Explanation:

      Brain stem is the base of the brain that connects the brain to the spinal cord. It consists of the mid brain, pons and medulla oblongata.

    • This question is part of the following fields:

      • Neuro-anatomy
      6.5
      Seconds

  • Question 26 - Transportation of proteins from the cell body to axonal terminals is known as:...

    Correct

    • Transportation of proteins from the cell body to axonal terminals is known as:

      Your Answer: Axoplasmic flow

      Explanation:

      Transportation of proteins from the cell body to axonal terminals is known as axoplasmic, axonal flow or Axonal transport.

    • This question is part of the following fields:

      • Neuro-anatomy
      6.3
      Seconds

  • Question 27 - Increase Gamma motor neuron activity produces what effect on the muscle spindle sensitivity?...

    Incorrect

    • Increase Gamma motor neuron activity produces what effect on the muscle spindle sensitivity?

      Your Answer: Significant decrease

      Correct Answer: Increase

      Explanation:

      The muscle spindle is supplied by both sensory and motor nerves. Sensory supply is Type Ia fibers whereas motor supply is via gamma motor neurons. These neurons also play a role in adjusting the sensitivity of muscle spindles. Increased neuron activity increases the muscle spindle sensitivity.

    • This question is part of the following fields:

      • Neuro-anatomy
      24.5
      Seconds

  • Question 28 - The thalamic nuclei that project over wide regions of the neocortex are: ...

    Correct

    • The thalamic nuclei that project over wide regions of the neocortex are:

      Your Answer: Specific relay nuclei

      Explanation:

      The thalamus is considered the relay station for sensory and motor stimuli. There are three basic types of thalamic nuclei: relay nuclei, association nuclei and non-specific nuclei. Relay nuclei receive very well defined inputs and project this signal to functionally distinct areas of the cerebral cortex. These include the nuclei that relay primary sensations and also the nuclei involved in feedback of cerebellar signals and basal gangliar output.

    • This question is part of the following fields:

      • Neuro-anatomy
      17.1
      Seconds

  • Question 29 - Which neurotransmitter is made from hydroxylation and decarboxylation of tryptophan? ...

    Correct

    • Which neurotransmitter is made from hydroxylation and decarboxylation of tryptophan?

      Your Answer: Serotonin

      Explanation:

      Serotonin is synthesized from the essential amino acid tryptophan. The rate-limiting step is the conversion of the amino acid to 5-hydroxytryptophan by tryptophan hydroxylase. This is then converted to serotonin by the aromatic L-amino acid decarboxylase.

    • This question is part of the following fields:

      • Neuro-anatomy
      9.4
      Seconds

  • Question 30 - Myelin sheath in the CNS is produced by? ...

    Correct

    • Myelin sheath in the CNS is produced by?

      Your Answer: Oligodendrocytes

      Explanation:

      CNS myelin is produced by special cells called oligodendrocytes. PNS myelin is produced by Schwann cells. The two types of myelin are chemically different, but they both perform the same function — to promote efficient transmission of a nerve impulse along the axon.

    • This question is part of the following fields:

      • Neuro-anatomy
      6.2
      Seconds

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