-
Question 1
Correct
-
The production of bile is increased by: Stimulation of the ____ nerve and the hormone ____.
Your Answer: Vagus, CCK
Explanation:Cholecystokinin is synthesized and secreted by enteroendocrine cells in the duodenum, the first segment of the small intestine, and causes the release of digestive enzymes and bile from the pancreas and gallbladder, respectively. It also acts as a hunger suppressant. Release of CCK is stimulated by monitor peptide released by pancreatic acinar cells as well as CCK-releasing protein, a paracrine factor secreted by enterocytes in the gastrointestinal mucosa. In addition, release of acetylcholine by the parasympathetic nerve fibers of the vagus nerve also stimulate its secretion.
-
This question is part of the following fields:
- Hepatobiliary
- Medicine
-
-
Question 2
Correct
-
Question 3
Correct
-
The functional unit of the liver is called?
Your Answer: Acini
Explanation:From a metabolic perspective, the functional unit is the hepatic acinus (terminal acinus), each of which is centred on the line connecting two portal triads and extends outwards to the two adjacent central veins. The periportal zone I is nearest to the entering vascular supply and receives the most oxygenated blood, making it least sensitive to ischemic injury while making it very susceptible to viral hepatitis. Conversely, the centrilobular zone III has the poorest oxygenation, and will be most affected during a time of ischemia.
-
This question is part of the following fields:
- Hepatobiliary
- Medicine
-
-
Question 4
Correct
-
The hepatic portal vein is a large vessel formed by which of the following veins?
Your Answer: All of the above
Explanation:The portal vein is usually formed by the confluence of the superior mesenteric and splenic veins and also receives blood from the inferior mesenteric, gastric, and cystic veins.
-
This question is part of the following fields:
- Hepatobiliary
- Medicine
-
-
Question 5
Correct
-
Cytochrome p450 enzymes expressed in hepatocytes serve to?
Your Answer: Facilitate oxidations or hydrolysis of drugs.
Explanation:Cytochrome p 450 are a family of proteins involved in drug metabolism which accounts for about 75% of the total metabolism. Most drugs are deactivated directly or by facilitated excretion from the body.
-
This question is part of the following fields:
- Hepatobiliary
- Medicine
-
-
Question 6
Correct
-
Question 7
Correct
-
Select the CORRECT statement regarding bile salts…
Your Answer: Are necessary for any bile acid secretion by hepatocytes.
Explanation:Bile salts stimulate bile secretion by the liver. Bile salts do not have an enzymatic action on digestion of fat but rather emulsify fat for the action of enzymes secreted mainly by the pancreas. Bile salts are polar cholesterol derivatives and are not derived from amino acids.
-
This question is part of the following fields:
- Hepatobiliary
- Medicine
-
-
Question 8
Correct
-
The main source of nutrients in the liver is via the
Your Answer: Portal vein
Explanation:The portal vein or hepatic portal vein is a blood vessel that carries blood from the gastrointestinal tract and spleen to the liver. This blood is rich in nutrients that have been extracted from food, and the liver processes these nutrients; it also filters toxins that may have been ingested with the food. 75% of total liver blood flow is through the portal vein, with the remainder coming from the hepatic artery proper.
-
This question is part of the following fields:
- Hepatobiliary
- Medicine
-
00
Correct
00
Incorrect
00
:
00
:
00
Session Time
00
:
00
Average Question Time (
Secs)