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  • Question 1 - Which neurotransmitter is made from hydroxylation and decarboxylation of tryptophan? ...

    Incorrect

    • Which neurotransmitter is made from hydroxylation and decarboxylation of tryptophan?

      Your Answer: Acetylcholine

      Correct Answer: Serotonin

      Explanation:

      Serotonin is synthesized from the essential amino acid tryptophan. The rate-limiting step is the conversion of the amino acid to 5-hydroxytryptophan by tryptophan hydroxylase. This is then converted to serotonin by the aromatic L-amino acid decarboxylase.

    • This question is part of the following fields:

      • Neuro-anatomy
      7.8
      Seconds

  • Question 2 - In a 60kg adult male with normal mean arterial pressure and oxygen consumption,...

    Incorrect

    • In a 60kg adult male with normal mean arterial pressure and oxygen consumption, what proportion of the cardiac output at rest goes to the brain?

      Your Answer: 15-20%

      Correct Answer: 10-15%

      Explanation:

      The rate of cerebral blood flow in the adult is typically 750 millilitres per minute, which is 10-15% of the cardiac output. On average around 13.9% of cardiac output is distributed to the brain.

    • This question is part of the following fields:

      • Neuro-anatomy
      11.1
      Seconds

  • Question 3 - The midbrain, medulla and pons, contain the following cranial nerve nuclei? ...

    Incorrect

    • The midbrain, medulla and pons, contain the following cranial nerve nuclei?

      Your Answer: CN 6 – 12

      Correct Answer: CN 3 - 12

      Explanation:

      The cranial nerves (with the exception of I and II) originate in the brainstem, which includes the midbrain, the pons, and the medulla.

    • This question is part of the following fields:

      • Neuro-anatomy
      1037.7
      Seconds

  • Question 4 - In response to tissue injury, which of these cannot sensitize and activate nociceptors?...

    Incorrect

    • In response to tissue injury, which of these cannot sensitize and activate nociceptors?

      Your Answer: Serotonin

      Correct Answer: Calcium

      Explanation:

      Histamine, serotonin, bradykinin and prostaglandin are all chemical mediators of inflammation with different distinct functions however all activate nociceptors. Calcium on the other hand cannot sensitize or activate nociceptors.

    • This question is part of the following fields:

      • Neuro-anatomy
      2.3
      Seconds

  • Question 5 - The primary visual cortex is located in the: ...

    Incorrect

    • The primary visual cortex is located in the:

      Your Answer: Parietal lobe

      Correct Answer: Occipital lobe

      Explanation:

      The primary visual cortex is located in the occipital lobe.

    • This question is part of the following fields:

      • Neuro-anatomy
      3.7
      Seconds

  • Question 6 - Myelin sheath in the CNS is produced by? ...

    Incorrect

    • Myelin sheath in the CNS is produced by?

      Your Answer: Microglial cells

      Correct Answer: Oligodendrocytes

      Explanation:

      CNS myelin is produced by special cells called oligodendrocytes. PNS myelin is produced by Schwann cells. The two types of myelin are chemically different, but they both perform the same function — to promote efficient transmission of a nerve impulse along the axon.

    • This question is part of the following fields:

      • Neuro-anatomy
      4.6
      Seconds

  • Question 7 - Cranial nerves VI, VII, VIII enter/exit the base of the brain at the:...

    Correct

    • Cranial nerves VI, VII, VIII enter/exit the base of the brain at the:

      Your Answer: Ponto-medullary junction

      Explanation:

      Cranial nerves III, IV and V exit from the pons, VI, VII, VIII exit from the pontomedullary junction and cranial nerve IX, X, XI, XII exit from the medulla.

    • This question is part of the following fields:

      • Neuro-anatomy
      12.6
      Seconds

  • Question 8 - Efferent innervation of the muscle spindle is supplied by which type of motor...

    Incorrect

    • Efferent innervation of the muscle spindle is supplied by which type of motor neuron?

      Your Answer: Alfa – motor neuron

      Correct Answer: Gama – motor neuron

      Explanation:

      The muscle spindle is supplied by both sensory and motor nerves. Sensory supply is via Type Ia fibers whereas the motor supply is via gamma motor neurons.

    • This question is part of the following fields:

      • Neuro-anatomy
      13.4
      Seconds

  • Question 9 - Activation of the cool receptor (CMR-1), causes: ...

    Incorrect

    • Activation of the cool receptor (CMR-1), causes:

      Your Answer: Influx of Ca++

      Correct Answer:

      Explanation:

      Cold and Menthol receptor 1 (CMR1) is a protein that in humans is encoded by TRPM8 gene. It is an ion channel which upon activation causes the influx of Na+ and Ca++ ions into the cell that leads to the depolarization and generation of an action potential.

    • This question is part of the following fields:

      • Neuro-anatomy
      12.7
      Seconds

  • Question 10 - Which statement is incorrect regarding nociceptor C fibers… ...

    Incorrect

    • Which statement is incorrect regarding nociceptor C fibers…

      Your Answer: Activity in the fiber activates a slow pain response

      Correct Answer: They are thinly myelinated

      Explanation:

      Group C nerve fibers are unmyelinated and have a small diameter, which means they conduct impulses at a low velocity. They carry sensory information and nociception.

    • This question is part of the following fields:

      • Neuro-anatomy
      6.2
      Seconds

  • Question 11 - Glucose transport in the brain is mediated by: ...

    Incorrect

    • Glucose transport in the brain is mediated by:

      Your Answer: GLUT 4

      Correct Answer: GLUT 1

      Explanation:

      The facilitative glucose transporter mediates the transport of glucose from blood into neurons and glia in the brain. The primary isoforms in the brain are GLUT1 detected at high concentrations.

    • This question is part of the following fields:

      • Neuro-anatomy
      26.4
      Seconds

  • Question 12 - The majority striatal neurons, called medium spiny neurons, utilizes which neurotransmitter? ...

    Incorrect

    • The majority striatal neurons, called medium spiny neurons, utilizes which neurotransmitter?

      Your Answer: Norepinephrine

      Correct Answer: GABA

      Explanation:

      Medium spiny neurons are inhibitory neurons which use GABA (gamma-aminobutyric acid) which exerts inhibitory actions. These cells represent 95% of neurones within the human striatum found in basal ganglia.

    • This question is part of the following fields:

      • Neuro-anatomy
      30.7
      Seconds

  • Question 13 - The nucleus tractus solitaries is medullary nucleus that processes the following inputs except:...

    Incorrect

    • The nucleus tractus solitaries is medullary nucleus that processes the following inputs except:

      Your Answer: Visceral sensation from the gut and thoracic organs

      Correct Answer: Sensory input from the semi-circular canal (CN VIII)

      Explanation:

      Located in the brain stem is a series of purely sensory nuclei known as tractus solitaries. Inputs of the nucleus tractus solitaries include:
      Taste information from the facial nerve (anterior 2/3 of the tongue), glossopharyngeal nerve (posterior 1/3) and vagus nerve (small area on the epiglottis).
      Sensory information from the ear (auricular branch of the vagus nerve).
      Chemoreceptors and mechanoreceptors of the general visceral afferent pathway (GVA) in the carotid body via glossopharyngeal nerve, aortic bodies, and the sinoatrial node, via the vagus nerve.
      Chemically and mechanically sensitive neurons of the general visceral afferent pathway (GVA) with endings located in the heart, lungs, airways, gastrointestinal system, pharynx, and liver via the glossopharyngeal and vagus nerves.

    • This question is part of the following fields:

      • Neuro-anatomy
      8.5
      Seconds

  • Question 14 - The brainstem contains which of the following structures? ...

    Incorrect

    • The brainstem contains which of the following structures?

      Your Answer: The midbrain, pons, medulla and cerebellum

      Correct Answer: The midbrain, pons and medulla

      Explanation:

      Brain stem is the base of the brain that connects the brain to the spinal cord. It consists of the mid brain, pons and medulla oblongata.

    • This question is part of the following fields:

      • Neuro-anatomy
      6.7
      Seconds

  • Question 15 - Where are the cell bodies to the preganglionic neurons located? ...

    Incorrect

    • Where are the cell bodies to the preganglionic neurons located?

      Your Answer: Forebrain

      Correct Answer: Midbrain

      Explanation:

      The cell bodies of the preganglionic neurons are located in the lateral grey column of the spinal cord and in the motor nuclei of the 3rd, 7th, 9th and 10th cranial nerves. These cranial nerves take origin from the midbrain.

    • This question is part of the following fields:

      • Neuro-anatomy
      3.8
      Seconds

  • Question 16 - The cerebellum consist of which three lobes? ...

    Incorrect

    • The cerebellum consist of which three lobes?

      Your Answer: Medial, lateral and flocculonodular

      Correct Answer: Anterior, posterior and flocculonodular

      Explanation:

      The cerebellum consists of 3 lobes; Anterior, Posterior and Flocculonodular lobe.

    • This question is part of the following fields:

      • Neuro-anatomy
      4.1
      Seconds

  • Question 17 - Cold receptors are likely to be active at the following temperatures except? ...

    Incorrect

    • Cold receptors are likely to be active at the following temperatures except?

      Your Answer: 15 °C

      Correct Answer: 39 °C

      Explanation:

      Cold and Menthol receptor 1 (CMR1) is a protein that in humans is encoded by TRPM8 gene. It is primarily responsible for the detection of temperatures ranging from 8-28 C. It is an ion channel which upon activation causes the influx of Na+ and Ca+ ions into the cell that leads to the depolarization and generation of an action potential.

    • This question is part of the following fields:

      • Neuro-anatomy
      12.7
      Seconds

  • Question 18 - Which receptor type is associated with the inhibition of pancreatic endocrine secretion? ...

    Incorrect

    • Which receptor type is associated with the inhibition of pancreatic endocrine secretion?

      Your Answer: Î’2

      Correct Answer: Α2

      Explanation:

      The activation of alpha 2-adrenergic receptors in pancreatic beta-cells works by inhibiting the secretion of insulin.

    • This question is part of the following fields:

      • Neuro-anatomy
      27.8
      Seconds

  • Question 19 - The axons of which neurons serve as the only output from the cerebellar...

    Incorrect

    • The axons of which neurons serve as the only output from the cerebellar cortex?

      Your Answer: Golgi

      Correct Answer: Purkinje

      Explanation:

      The cerebellar cortex consist of 3 layers. The molecular layer, the granule cell layer and the Purkinje cell layer in the middle. The Purkinje cells project into the deep cerebellar nuclei. They are the only output cells of the cerebellar cortex.

    • This question is part of the following fields:

      • Neuro-anatomy
      14
      Seconds

  • Question 20 - Which of the following forms the language areas of the cerebral cortex? ...

    Incorrect

    • Which of the following forms the language areas of the cerebral cortex?

      Your Answer: Wernicke’s area

      Correct Answer: All of the above

      Explanation:

      Broca’s area, Wernicke’s area, the submarginal sulcus and the angular gyrus all form the language areas of the cerebral cortex.

    • This question is part of the following fields:

      • Neuro-anatomy
      19.4
      Seconds

  • Question 21 - Visceral afferent fibers are found in the following areas except the…? ...

    Incorrect

    • Visceral afferent fibers are found in the following areas except the…?

      Your Answer: Glossopharyngeal nerve

      Correct Answer: Trigeminal nerve

      Explanation:

      The general visceral afferent (GVA) fibers carry impulses from viscera to the central nervous system. The cranial nerves that contain GVA fibers include the facial nerve, the glossopharyngeal nerve and the vagus nerve

    • This question is part of the following fields:

      • Neuro-anatomy
      9.6
      Seconds

  • Question 22 - The basic taste “umami” is mediated by glutamate acting on a metabotropic receptor...

    Incorrect

    • The basic taste “umami” is mediated by glutamate acting on a metabotropic receptor named:

      Your Answer: Gustducin

      Correct Answer: mGluR4

      Explanation:

      Umami taste or savoury taste is one of the five basic tastes described as meaty or brothy. The basic taste “umami” is mediated by glutamate acting on a metabotropic receptor named mGluR4 (metabotropic glutamate receptor 4). Additionally, umami taste is also mediated by the T1R1/T1R3 heterodimer, which is a combination of two G protein-coupled receptors. These receptors are responsible for detecting the presence of glutamate and other amino acids, contributing to the savory flavor characteristic of umami.

    • This question is part of the following fields:

      • Neuro-anatomy
      3.5
      Seconds

  • Question 23 - Into how many functional units can the cerebellum be divided? ...

    Incorrect

    • Into how many functional units can the cerebellum be divided?

      Your Answer: 2

      Correct Answer: 3

      Explanation:

      The functional division of the cerebellum are the: Vestibulocerebellum (floculonodular lobe), Spinocerebellum (vermis and associated areas in the midline) and cerebrocerebellum (lateral hemispheres).

    • This question is part of the following fields:

      • Neuro-anatomy
      15.2
      Seconds

  • Question 24 - Which part of the cerebellum is primarily responsible for equilibrium and eye movements?...

    Correct

    • Which part of the cerebellum is primarily responsible for equilibrium and eye movements?

      Your Answer: Vestibulocerebellum

      Explanation:

      The vestibulocerebellum develops at the same time as the vestibular apparatus in the inner ear. Its regulates balance between agonist and antagonist muscle contractions of the spine, hips, and shoulders during rapid movements.

    • This question is part of the following fields:

      • Neuro-anatomy
      10.8
      Seconds

  • Question 25 - Which of the following are exclusively innervated by parasympathetic nerves? ...

    Correct

    • Which of the following are exclusively innervated by parasympathetic nerves?

      Your Answer: Circular muscle of iris

      Explanation:

      Circular muscle of iris is exclusively supplied by the parasympathetic nerves.

    • This question is part of the following fields:

      • Neuro-anatomy
      7.7
      Seconds

  • Question 26 - In Argyll Robertson pupils… ...

    Incorrect

    • In Argyll Robertson pupils…

      Your Answer: It may occur in CNS syphilis

      Correct Answer: All of the above

      Explanation:

      Argyll Robertson pupils are bilaterally small pupils that accommodate or reduce in size near an object but do not react to light. They do not constrict when exposed to bright light. They are a highly specific sign of neurosyphilis but may be seen in diabetic neuropathy as well.

    • This question is part of the following fields:

      • Neuro-anatomy
      9
      Seconds

  • Question 27 - Which one of the following cells originates from a monocyte and resembles a...

    Incorrect

    • Which one of the following cells originates from a monocyte and resembles a macrophage?

      Your Answer: Astrocyte

      Correct Answer: Microglia

      Explanation:

      Microglia act as the macrophages of the central nervous system, and they contribute to innate and adaptive immune responses. Studies have shown that microglial cells recognize monocyte antigens, and there are similarities between them that demonstrate that they originate from these monocytes.

    • This question is part of the following fields:

      • Neuro-anatomy
      4.3
      Seconds

  • Question 28 - Which of the following is a form of synaptic plasticity? ...

    Incorrect

    • Which of the following is a form of synaptic plasticity?

      Your Answer: Confabulation

      Correct Answer: Working memory

      Explanation:

      Synaptic plasticity is an important neurochemical foundation of working memory and generation of memory. Synaptic plasticity is the ability of synapses to strengthen or weaken over time in response to increases or decreases in their activity.

    • This question is part of the following fields:

      • Neuro-anatomy
      7.2
      Seconds

  • Question 29 - The brainstem reticular formation, consists of which important control system responsible for consciousness...

    Incorrect

    • The brainstem reticular formation, consists of which important control system responsible for consciousness and sleep?

      Your Answer: Rs reticular system

      Correct Answer: RAS reticular activating system

      Explanation:

      The reticular formation is a set of interconnected nuclei that are located along the brainstem. Reticular activating system (RAS) is a set of connected nuclei in the brain that is responsible for regulating wakefulness and sleep wake transitions and is the most influential component in the reticular formation.

    • This question is part of the following fields:

      • Neuro-anatomy
      6.3
      Seconds

  • Question 30 - Regarding the innervation of the cerebral blood vessels, postganglionic sympathetic neurons have their...

    Incorrect

    • Regarding the innervation of the cerebral blood vessels, postganglionic sympathetic neurons have their cell bodies in the:

      Your Answer:

      Correct Answer: Superior cervical ganglia

      Explanation:

      The superior cervical ganglion (SCG) is a part of autonomic system which plays a major role in maintaining homeostasis of the body. This ganglion innervates structures in the head and neck and is the largest and the most superiorly located ganglion. The SCG provides sympathetic innervation to structures within the head, including the pineal gland, the blood vessels in the cranial muscles and the brain, the choroid plexus, the eyes, the lacrimal glands, the carotid body, the salivary glands, and the thyroid gland. The postganglionic axons of the SCG innervate the internal carotid artery and form the internal carotid plexus. The internal carotid plexus carries the postganglionic axons of the SCG to the eye, lacrimal gland, mucous membranes of the mouth, nose, and pharynx, and numerous blood-vessels in the head.

    • This question is part of the following fields:

      • Neuro-anatomy
      0
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Neuro-anatomy (24/29) 83%
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