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  • Question 1 - Which Immunoglobulin (or antibody) is secreted in large amounts in breast milk? ...

    Correct

    • Which Immunoglobulin (or antibody) is secreted in large amounts in breast milk?

      Your Answer: IgA

      Explanation:

      The major constituents of breast milk are lactose, protein, fat and water. However, the composition of breast milk is not constant; early lactation differs from late lactation, one feed differs from the next, and the composition can even change
      during a feed. Artificial infant formulas cannot therefore be identical to breast milk. In addition to IgA, breast milk contains small amounts of IgM and IgG and other factors such as lactoferrin, macrophages, complement and lysozymes

    • This question is part of the following fields:

      • Immunology
      3
      Seconds

  • Question 2 - Which immunoglobulin provides passive immunity to the neonate? ...

    Correct

    • Which immunoglobulin provides passive immunity to the neonate?

      Your Answer: IgG

      Explanation:

      Passive immunity to the neonate is provided by immunoglobulin G (IgG) since it can be transferred through the placenta from mother to the foetus.
      IgA is transferred from mothers to offspring through breast milk.
      IgM molecular structure is too big to be filtered through the placental vasculature to the foetus. IgM is the first Ig to be synthesised by the neonate

    • This question is part of the following fields:

      • Immunology
      3.9
      Seconds

  • Question 3 - You see a patient in antenatal clinic who is concerned that she has...

    Incorrect

    • You see a patient in antenatal clinic who is concerned that she has never had chicken pox and may catch it during pregnancy. You check her Varicella status and she is non-immune. She asks you about vaccination. What type of vaccine is the varicella vaccine?

      Your Answer:

      Correct Answer: Attenuated

      Explanation:

      Varicella is a live vaccine. The recent RCOG green top guidelines suggest vaccine can be considered postpartum or pre pregnancy but NOT whilst pregnant. In the non-immune pregnant woman they should be advised to avoid contact with people with chickenpox or shingles and to contact a healthcare professional promptly if exposed. If they have a significant exposure VZIG should be offered as soon as possible.

    • This question is part of the following fields:

      • Immunology
      0
      Seconds

  • Question 4 - Macrophages are derived from what type of white blood cell? ...

    Incorrect

    • Macrophages are derived from what type of white blood cell?

      Your Answer:

      Correct Answer: Monocytes

      Explanation:

      Macrophages are derived from monocytes. When monocytes come across a pathogen they differentiate into macrophages for phagocytosis to occur.

    • This question is part of the following fields:

      • Immunology
      0
      Seconds

  • Question 5 - Haemolytic Disease of the New-born falls into what type of hypersensitivity reaction? ...

    Incorrect

    • Haemolytic Disease of the New-born falls into what type of hypersensitivity reaction?

      Your Answer:

      Correct Answer: Type II

      Explanation:

      It is classified under type II hypersensitivity reaction. Antibodies are formed against the rhesus antigen i.e. D antigen. Hence when the Antibody reacts with the antigen on the RBC it results in activation of the complement cascade leading to lysis.

    • This question is part of the following fields:

      • Immunology
      0
      Seconds

  • Question 6 - The Mantoux test utilises what type of hypersensitivity reaction? ...

    Incorrect

    • The Mantoux test utilises what type of hypersensitivity reaction?

      Your Answer:

      Correct Answer: Type IV

      Explanation:

      The Mantoux test is based on type IV hypersensitivity reaction.

    • This question is part of the following fields:

      • Immunology
      0
      Seconds

  • Question 7 - Which immunoglobulin is the first to be synthesised by the neonate? ...

    Incorrect

    • Which immunoglobulin is the first to be synthesised by the neonate?

      Your Answer:

      Correct Answer: IgM

      Explanation:

      Fetal production of immunoglobulin begins early on at about 10 weeks gestation with the production of IgM antibodies. Maternal IgG, which is a key component of fetal immunity is passed on to the foetus through the placenta from 12 weeks of gestation. Secretory IgA is not produced until after birth, through breast milk.

    • This question is part of the following fields:

      • Immunology
      0
      Seconds

  • Question 8 - Rhesus D immunoglobin treatment utilises what class of antibody? ...

    Incorrect

    • Rhesus D immunoglobin treatment utilises what class of antibody?

      Your Answer:

      Correct Answer: IgG

      Explanation:

      It utilizes the IgG class of the antibody.

    • This question is part of the following fields:

      • Immunology
      0
      Seconds

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Immunology (2/2) 100%
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