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  • Question 1 - Which of the following cell types act as professional antigen presenter cells (APCs)...

    Incorrect

    • Which of the following cell types act as professional antigen presenter cells (APCs)

      Your Answer: Neutrophils

      Correct Answer: Macrophages

      Explanation:

      Macrophages are the antigen presenting cells, they phagocytose the pathogen and after breaking them down present their protein structure to the B and T cells for a specific immune reaction to take place.

    • This question is part of the following fields:

      • Immunology
      16.2
      Seconds

  • Question 2 - You have just clerked in a patient on the labour ward who has...

    Correct

    • You have just clerked in a patient on the labour ward who has SLE. What type of hypersensitivity reaction is SLE an example of?

      Your Answer: Type III

      Explanation:

      SLE is a type III hypersensitivity reaction

    • This question is part of the following fields:

      • Immunology
      2.8
      Seconds

  • Question 3 - Fetal immunoglobulin production begins at what gestation? ...

    Correct

    • Fetal immunoglobulin production begins at what gestation?

      Your Answer: Week 10

      Explanation:

      Fetal production of immunoglobulin begins early on, at about 10 weeks gestation with the production of IgM antibodies. Maternal IgG, which is a key component of fetal immunity, is passed on to the foetus through the placenta from 12 weeks of gestation. Secretory IgA is not produced until after birth.

    • This question is part of the following fields:

      • Immunology
      6.9
      Seconds

  • Question 4 - At what stage of gestation does fetal immunoglobulin M production begin? ...

    Correct

    • At what stage of gestation does fetal immunoglobulin M production begin?

      Your Answer: Week 10

      Explanation:

      Maternofetal IgG transfer starts around week 12. Fetal production IgM starts around week 10 to 11.

    • This question is part of the following fields:

      • Immunology
      4.6
      Seconds

  • Question 5 - Which of the following increases in pregnancy? ...

    Incorrect

    • Which of the following increases in pregnancy?

      Your Answer: IL-2

      Correct Answer: Th2

      Explanation:

      T-Helper cells type 2 increase during pregnancy. They secret cytokines IL-4,5,9,10 and 13.

    • This question is part of the following fields:

      • Immunology
      27.9
      Seconds

  • Question 6 - Which of the following is a tumour marker for ovarian cancer? ...

    Correct

    • Which of the following is a tumour marker for ovarian cancer?

      Your Answer: Ca 125

      Explanation:

      CA-125 is the tumour marker specific for ovarian carcinoma.

    • This question is part of the following fields:

      • Immunology
      4.5
      Seconds

  • Question 7 - To avoid potential haemolysis, Anti D immunoglobulin should be administered to which of...

    Correct

    • To avoid potential haemolysis, Anti D immunoglobulin should be administered to which of the following?

      Your Answer: Rhesus negative mother, non-sensitised, fetal cord blood Rh positive

      Explanation:

      The Rhesus status of a mother is important in pregnancy and even abortion. The exposure of an Rh-negative mother exposed to Rh antigens from a positive foetus, will influence the development of anti-Rh antibodies. This may cause problems in subsequent pregnancies leading to haemolysis in the newborn. Rh Anti RhD- globulin is therefore given to non-sensitised Rh-negative mothers who give birth to Rh-positive children to prevent the formation of anti-Rh antibodies. Anti RhD globulin is not useful for already sensitized, or RhD positive mothers; its administration could result in maternal blood being bound and taken out of circulation.

    • This question is part of the following fields:

      • Immunology
      33.5
      Seconds

  • Question 8 - At what stage of gestation does maternal immunoglobulin G transfer to the foetus...

    Correct

    • At what stage of gestation does maternal immunoglobulin G transfer to the foetus start?

      Your Answer: 12 weeks

      Explanation:

      Transportation of the maternal IgG through the placenta starts around the 12 week of gestation.

    • This question is part of the following fields:

      • Immunology
      2.5
      Seconds

  • Question 9 - Which Immunoglobulin (or antibody) is secreted in large amounts in breast milk? ...

    Correct

    • Which Immunoglobulin (or antibody) is secreted in large amounts in breast milk?

      Your Answer: IgA

      Explanation:

      When considering immunoglobulins in neonates. There are only a few key points you are likely to be tested on. 1. IgA is resistant to stomach acid and found in large amounts in breast milk. 2. IgG is the only Ig that can cross the placenta so is key for passive neonatal immunity 3. When the neonate starts synthesising its own Ig it is IgM that is produced first.

    • This question is part of the following fields:

      • Immunology
      2.3
      Seconds

  • Question 10 - Which of the following will require Anti-D administration post partum? ...

    Correct

    • Which of the following will require Anti-D administration post partum?

      Your Answer: Rhesus negative mother, non-sensitised, fetal cord blood Rh positive

      Explanation:

      Rhesus positive mothers should not get anti-D. They have Rhesus antigens and the anti-D would result in maternal blood being bound and removed from her circulation. The danger is to children born to mothers who are rhesus negative. As the mother may develop antibodies against Rhesus positive fetal blood. Therefore if the baby is Rhesus negative then there is no risk of alloimmunisation (sensitisation)

    • This question is part of the following fields:

      • Immunology
      6.7
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Immunology (8/10) 80%
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