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  • Question 1 - Endometriosis is an example of which of the following? ...

    Correct

    • Endometriosis is an example of which of the following?

      Your Answer: Pathological hyperplasia

      Explanation:

      Endometriosis is a condition in which the endometrial tissue lies outside the endometrial cavity. There are 4 theories which explain this. First is pathological hyperplasia resulting in menstrual regurgitation and implantation, second is the coelomic epithelium transformation, third is immunogical factors and the fourth is via the lymphatic or vascular spread.

    • This question is part of the following fields:

      • Clinical Management
      4.2
      Seconds
  • Question 2 - Which of the following dugs is a strong inducer of cytochrome P450? ...

    Correct

    • Which of the following dugs is a strong inducer of cytochrome P450?

      Your Answer: Phenytoin

      Explanation:

      It is important to be aware of which ant-epileptics induce cytochrome P450. Of the above Topiramate and Phenytoin are moderate and strong inducers respectively.

    • This question is part of the following fields:

      • Clinical Management
      5.5
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  • Question 3 - At what gestational age does the luteo-placental shift occur? ...

    Correct

    • At what gestational age does the luteo-placental shift occur?

      Your Answer: 6-8 weeks

      Explanation:

      Luteo-placental shifts occurs around 6-8 week when the placenta takes over from the corpus luteum as the main producer of oestrogen and progesterone.

    • This question is part of the following fields:

      • Clinical Management
      4.5
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  • Question 4 - Which of the following is associated with use of a tocolytic drug? ...

    Correct

    • Which of the following is associated with use of a tocolytic drug?

      Your Answer: Prolongation of pregnancy for up to 7 days

      Explanation:

      The WHO recommends that tocolytics can safely be used to prolong pregnancy for up to seven days. The tocolytic drugs are used to suppress contractions to allow for more favourable conditions in the case of preterm labour, such as transfer to a better-equipped health care facility with a neonatal intensive care unit, or for those who have not yet completed a full dose of corticosteroids. It is not however associated with better neonatal outcomes in the imminent delivery of preterms. Examples of tocolytics include calcium channel blockers, magnesium sulphate, and oxytocin antagonists.

    • This question is part of the following fields:

      • Clinical Management
      7
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  • Question 5 - Regarding Venous Thromboembolism (VTE) in pregnancy which of the following statements is TRUE?...

    Correct

    • Regarding Venous Thromboembolism (VTE) in pregnancy which of the following statements is TRUE?

      Your Answer: Relative risk of VTE in pregnancy is 4 to 6 fold

      Explanation:

      Venous thromboembolic disease (VTE) is the most common cause of direct maternal death in the UK. In the most recent triennium, there were 41 fatalities, giving a maternal mortality rate of 1.94 per 100 000 – more than twice that of the next most common cause, pre-eclampsia. As pregnancy is a hyper coagulable state. There are alterations in the fibrinolytics and thrombotic pathways. There is also an increased production of clotting factors during pregnancy.

    • This question is part of the following fields:

      • Clinical Management
      7
      Seconds
  • Question 6 - A 21 year old patient presents to the clinic with a 48 hour...

    Correct

    • A 21 year old patient presents to the clinic with a 48 hour history of unprotected sexual intercourse. She is not on any form of contraception. After discussion you prescribe a dose of Ulipristal 30 mg stat. Which of the following would be the appropriate advice regarding vomiting?

      Your Answer: If vomiting occurs within 3 hours a repeat dose should be taken

      Explanation:

      Ulipristal acetate is a selective progesterone receptor modulator which regulates the luteinizing hormone (LH) surge, preventing ovulation. This emergency contraceptive can be used up to five days after unprotected sexual intercourse and is given as a 30mg oral dose. If vomiting occurs within three hours, then a second tablet is needed to ensure its effects.

    • This question is part of the following fields:

      • Clinical Management
      18.2
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  • Question 7 - Stages of labour ...

    Correct

    • Stages of labour

      Your Answer: The third stage ends with the delivery of the placenta and membranes

      Explanation:

      First stage: The latent phase is generally defined as beginning at the point at which the woman perceives regular uterine contractions. A definition of active labour in a British journal was having contractions more frequent than every 5 minutes, in addition to either a cervical dilation of 3 cm or more or a cervical effacement of 80% or more.

      Second stage: fetal expulsion begins when the cervix is fully dilated, and ends when the baby is born.

      Third stage: placenta delivery – The period from just after the foetus is expelled until just after the placenta is expelled is called the third stage of labour or the involution stage.

    • This question is part of the following fields:

      • Clinical Management
      7.9
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  • Question 8 - A 55 year old patient with a who has tried unsuccessful conservative measures...

    Correct

    • A 55 year old patient with a who has tried unsuccessful conservative measures for her overactive bladder, would like to consider Oxybutynin. She wants to know how common dry mouth is as a side effect, as her sister suffered from it on while on the same drug.

      Your Answer: approximately 1 in 10 patients

      Explanation:

      Urinary incontinence can be divided into two main aetiologies, stress incontinence, or overactive bladder. Conservative management include lifestyle interventions, controlling fluid intake, or bladder exercises. If conservative management is no longer efficient, then medications may be indicated. Oxybutynin is an anticholinergic drug used in the treatment of urinary incontinence. As with other anticholinergic drugs, side effects include dry mouth, dry eyes, blurry vision and constipation. About 1 in 10 patients taking Oxybutynin will experience some of these side effects.

    • This question is part of the following fields:

      • Clinical Management
      734.5
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  • Question 9 - Which of the following fasting plasma glucose (FPG) values for OGTT (Oral glucose...

    Correct

    • Which of the following fasting plasma glucose (FPG) values for OGTT (Oral glucose tolerance test) is diagnostic of gestational diabetes according to the WHO criteria?

      Your Answer: FPG 6.1mmol/L; 2 hour 7.8mmol/L

      Explanation:

      There are several criteria that aid in the diagnosis of gestational diabetes in pregnancy including NICE, WHO and modified WHO:
      GDM Diagnostic Criteria:
      NICE: Immediate FBG >5.6, 2 hour glucose >7.8
      WHO: Immediate FBG >6.1, 2 hour glucose >7.8
      Modified WHO: Immediate FBG >7.1, 2 hour glucose >7.8

      Random glucose and OGTT 2 hour readings of >11.1 are diagnostic of diabetes in non-pregnant states but are not part of the gestational diabetes criteria.

    • This question is part of the following fields:

      • Clinical Management
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  • Question 10 - A patient undergoes medical abortion at 9 weeks gestation. What is the advice...

    Correct

    • A patient undergoes medical abortion at 9 weeks gestation. What is the advice regarding Rhesus Anti-D Immunoglobulin?

      Your Answer: All RhD-negative women who are not alloimmunized should receive Anti-D IgG

      Explanation:

      All non-sensitised RhD negative women should receive Anti-D IgG within 72 hours following abortion

    • This question is part of the following fields:

      • Clinical Management
      17.6
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  • Question 11 - A 46 year old lady presents to the gynaecology clinic with a one...

    Incorrect

    • A 46 year old lady presents to the gynaecology clinic with a one month history of vulval soreness and lumps. She smokes several packs of tobacco cigarettes a day. A biopsy confirms vulvar intraepithelial neoplasia. What is her risk of developing squamous cell carcinoma?

      Your Answer: <0.5%

      Correct Answer: 15%

      Explanation:

      Vulvar Intraepithelial Neoplasia (VIN) is a non-invasive squamous type lesion that carries a 15% chance of developing into squamous cell carcinoma of the vulva. Human Papillomavirus (HPV) infection, or chronic inflammatory conditions such as lichen sclerosis and lichen planus, can cause changes in the basal cells of the vulvar epithelium. Other risk factors of VIN include multiple sexual partners, cigarette smoking, and immunocompromised states. Diagnosis is by clinical examination and a biopsy confirms neoplasia.

    • This question is part of the following fields:

      • Clinical Management
      17.4
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  • Question 12 - What is the male infertility rate in CF patients? ...

    Correct

    • What is the male infertility rate in CF patients?

      Your Answer: 98%

      Explanation:

      Cystic fibrosis is the most common fetal genetic disease in Caucasians and has an autosomal recessive inheritance. It is caused by an abnormal chloride channel due to a defect in the CFTR gene. Complications range from haemoptysis, respiratory failure, biliary cirrhosis, diabetes and male infertility. Men with CF are infertile in 98% of the cases due to failure of development of the vas deference.

    • This question is part of the following fields:

      • Clinical Management
      3.5
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  • Question 13 - A patients MSU comes back showing heavy growth of E.coli that is resistant...

    Correct

    • A patients MSU comes back showing heavy growth of E.coli that is resistant to trimethoprim, amoxicillin and nitrofurantoin. You decide to prescribe a course of Cephalexin. What is the mechanism of action of Cephalexin?

      Your Answer: inhibit peptidoglycan cross-links in bacterial cell wall

      Explanation:

      Cephalosporins are beta lactum drugs, like penicillin. They act by inhibiting the cross linkage of the peptidoglycan wall in bacteria.

    • This question is part of the following fields:

      • Clinical Management
      25.9
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  • Question 14 - A 38 year old women attends clinic follow up. You note pelvic ultrasound...

    Correct

    • A 38 year old women attends clinic follow up. You note pelvic ultrasound shows a 36mm simple cyst. What is the most appropriate course of action regarding this cyst according to the RCOG green top guidelines?

      Your Answer: Discharge with no follow up

      Explanation:

      As this is a simple cyst less than 50mm in diameter the patient does not require further investigation or routine follow up

    • This question is part of the following fields:

      • Clinical Management
      9.2
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  • Question 15 - Which of the following hormones inhibits lactogenesis during pregnancy? ...

    Correct

    • Which of the following hormones inhibits lactogenesis during pregnancy?

      Your Answer: Oestrogen and Progesterone

      Explanation:

      Under the influence of prolactin, oestrogen and progesterone and human placental lactogen (hPL), the mammary epithelium proliferates but remains presecretory during mammogenesis. Lactogenesis is inhibited by high circulating levels of progesterone and oestrogen which block cortisol binding sites. Cortisol would have otherwise have worked synergistically with prolactin in milk production. A sharp decrease in progesterone levels after delivery allows prolactin and oxytocin to stimulate milk production and the milk ejection reflex in response to suckling. Prolactin continues to maintain milk production in galactopoiesis.

    • This question is part of the following fields:

      • Clinical Management
      3.9
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  • Question 16 - At what gestation does a mother typically first become aware of fetal movements?...

    Correct

    • At what gestation does a mother typically first become aware of fetal movements?

      Your Answer: 18-20 weeks

      Explanation:

      Typically fetal movements become apparent by 18-20 weeks

    • This question is part of the following fields:

      • Clinical Management
      5.4
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  • Question 17 - What percentage of pregnancies will be uncomplicated following a single episode of reduced...

    Correct

    • What percentage of pregnancies will be uncomplicated following a single episode of reduced fetal movements?

      Your Answer: 70%

      Explanation:

      Reduced fetal movements can be the first indication of possible fetal abnormalities. Movements are first perceived by the mother from about 18-20 weeks gestation, increase in size and frequency until 32 weeks gestation when they plateau at about 31 movements per hour. Investigations for reduced fetal heart rate include auscultation of the fetal heart rate using a handheld doppler device, and a cardiotocograph or ultrasound if the foetus is above 28 weeks gestation. About 70% of women who experience one episode of reduced fetal movement have uncomplicated pregnancies. They are advised to report to a maternal unit if another episode occurs.

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      • Clinical Management
      8.3
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  • Question 18 - Which one of the following aetiological factors causes a reduction in the risk...

    Correct

    • Which one of the following aetiological factors causes a reduction in the risk of fibroids?

      Your Answer: Pregnancy

      Explanation:

      Risk of fibroids is more common among African ethnicity and is also related to obesity and early puberty. The role of combined oral contraceptive pills is still debatable and its results are conflicting, whereas the risk of fibroids decreases with the increase in number of pregnancies. i.e. multiparous women have a lower risk of fibroids.

    • This question is part of the following fields:

      • Clinical Management
      7.1
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  • Question 19 - Which of the following hormones inhibits Galactopoiesis and Lactogenesis postpartum? ...

    Correct

    • Which of the following hormones inhibits Galactopoiesis and Lactogenesis postpartum?

      Your Answer: Dopamine

      Explanation:

      Galactopoiesis and Lactogenesis are stimulated by Prolactin. Dopamine released under hypothalamic control inhibits Prolactin production. Note oestrogen and progesterone inhibit lactogenesis up until term.

    • This question is part of the following fields:

      • Clinical Management
      5.3
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  • Question 20 - A 27 year old women presents with a history of vaginal spotting and...

    Correct

    • A 27 year old women presents with a history of vaginal spotting and cramping abdominal pain. She has an 8 week history of amenorrhoea. On examination urine pregnancy test is positive and the cervix is closed. What is the likely diagnosis?

      Your Answer: Threatened Miscarriage

      Explanation:

      Miscarriage is a pregnancy that ends spontaneously before the foetus reaches the age of viability i.e. before 24 weeks of gestation. In a threatened miscarriage the USG findings are of a foetus present in the uterus and on speculum examination the cervical OS is closed, in an inevitable miscarriage the cervical OS is opened. In an incomplete miscarriage the uterus contains the retained products of conception and the cervical OS is open. complete miscarriage contains no retained products of conception and the cervix is closed as the bleeding as resolved.

    • This question is part of the following fields:

      • Clinical Management
      56.8
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  • Question 21 - A patient asks you in clinic when she can start trying to conceive...

    Correct

    • A patient asks you in clinic when she can start trying to conceive again. She has just completed chemotherapy for gestational trophoblastic disease (GTD)?

      Your Answer: 1 year from completion of treatment

      Explanation:

      According to the RCOG greentop guidelines, a women who have underdone chemotherapy for GTD are advised not to conceive for 1 years after completion of the chemotherapy.

    • This question is part of the following fields:

      • Clinical Management
      12.8
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  • Question 22 - A 30 year old patient attends for non-invasive pre-natal screening for Down's syndrome....

    Correct

    • A 30 year old patient attends for non-invasive pre-natal screening for Down's syndrome. You advise her that the result will take the form of a risk score and higher risk results will be offered CVS or amniocentesis. What is the cut-off figure between low and high risk?

      Your Answer: 1 in 150

      Explanation:

      1 in 150 is the cut off. Where pre-natal screening shows a risk of 1 in 150 or greater invasive testing is typically offered.

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      • Clinical Management
      11.4
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  • Question 23 - You receive a swab result from a patient who had complained of odorous...

    Correct

    • You receive a swab result from a patient who had complained of odorous vaginal discharge. It confirms bacterial vaginosis (BV). Which pathogen is most commonly associated with BV?

      Your Answer: Gardnerella vaginalis

      Explanation:

      BV typically presents as an increase in vaginal discharge and vaginal malodour caused by a change in vaginal bacterial flora. PV discharge due to BV is typically grey fluid that adheres to the vaginal mucosa. BV is a polymicrobial infection. Gardnerella is the most commonly associated pathogen. Other associated bacteria include Lactobacillus species, Prevotella, Mobiluncus, Bacteroides, Peptostreptococcus, Fusobacterium, Veillonella, Eubacterium species, Mycoplasma hominis, Urea plasma urealyticum and Streptococcus viridans.

    • This question is part of the following fields:

      • Clinical Management
      8.8
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  • Question 24 - Regarding pelvic Gonorrhoea infection in women. What percentage of cases are asymptomatic? ...

    Correct

    • Regarding pelvic Gonorrhoea infection in women. What percentage of cases are asymptomatic?

      Your Answer: 50%

      Explanation:

      Gonorrhoea is a sexually transmitted disease that is caused by Neisseria gonorrhoea. It infects the mucous membrane of the genital tract epithelium in the endocervical and the urethral mucosa. Around 50% of the women are asymptomatic. However it presents as increase vaginal discharge, dysuria, proctitis and pelvic tenderness.

    • This question is part of the following fields:

      • Clinical Management
      6.8
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  • Question 25 - Regarding gestational diabetes which of the following statements is TRUE? ...

    Correct

    • Regarding gestational diabetes which of the following statements is TRUE?

      Your Answer: it occurs in 2-5% of pregnancies

      Explanation:

      Gestational Diabetes occurs in 2-9% of all the pregnancies.

    • This question is part of the following fields:

      • Clinical Management
      8.4
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  • Question 26 - A patient is being discharged following a termination of pregnancy at 14 weeks....

    Correct

    • A patient is being discharged following a termination of pregnancy at 14 weeks. She had been taking a combined oral contraceptive pill in the past but stopped taking this 6 months prior to falling pregnant as she wasn't in a serious relationship. When should she start again?

      Your Answer: Start immediately

      Explanation:

      Following an abortion or miscarriage, combined oral contraceptive pills should be started immediately.

    • This question is part of the following fields:

      • Clinical Management
      9.6
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  • Question 27 - The COCP (Combined Oral Contraceptive Pill) causes all of the following biochemical effects...

    Correct

    • The COCP (Combined Oral Contraceptive Pill) causes all of the following biochemical effects EXCEPT?

      Your Answer: Elevate FSH

      Explanation:

      COCP’s act both centrally and peripherally. They inhibit ovulation. Both oestrogen and progestogen supress the release of FSH and LH hence preventing ovulation. Peripherally it acts by making the endometrium atrophic and hostile towards implantation. It also alters the cervical mucus and prevents the sperm from ascending the uterine cavity.

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      • Clinical Management
      6.1
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  • Question 28 - What is the most common causative organism in Fitzhugh Curtis syndrome and ophthalmic...

    Correct

    • What is the most common causative organism in Fitzhugh Curtis syndrome and ophthalmic neonatorum?

      Your Answer: Chlamydia trachomatis

      Explanation:

      A rare complication of pelvic inflammatory disease is Fitz Hugh Curtis syndrome which is perihepatitis leading to the formation of adhesions between the liver and the peritoneal surface. It is most commonly caused by chlamydia and gonorrhoea. Ophthalmia neonatorum is conjunctivitis which is also caused by these pathogens.

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      • Clinical Management
      5.5
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  • Question 29 - A patient admitted to the medical ward complains of a mild fever and...

    Correct

    • A patient admitted to the medical ward complains of a mild fever and vaginal discharge. Clue cells are seen on microscopy from a vaginal swab. Which of the following infections feature clue cells?

      Your Answer: Bacterial Vaginosis

      Explanation:

      Bacterial vaginosis (BV) is a common infection of the vagina caused by the overgrowth of atypical bacteria, most commonly Gardnerella vaginalis, a gram-negative rod. In diagnosing BV, a swab is taken for microscopy, often revealing clue cells. Clue cells are cells of the vaginal epithelium which are covered by adherent Gardnerella, giving them a distinctive look under the microscope. Though many are asymptomatic, some infected women complain of a greyish, foul-smelling vaginal discharge. Their vaginal fluid pH may also become more alkaline. BV does not however present with pyrexia, so the lady’s fever could be attributed to another cause as she is still a patient on the medical ward.

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      • Clinical Management
      15.6
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  • Question 30 - You are called to see a patient in A&E who attended due to...

    Correct

    • You are called to see a patient in A&E who attended due to finger splinter that has been removed. The HCA took some routine obs that show her blood pressure to be 162/110. She is 32 weeks pregnant. According to the NICE guidelines which of the following is appropriate?

      Your Answer: Admit and start oral labetalol

      Explanation:

      BP over 159/109 is classed as Severe. NICE guidance advises admission and treatment with oral Labetalol as 1st Line. Patient should have BP checked QDS and shouldn’t be discharged until BP is below 159/109

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      • Clinical Management
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  • Question 31 - Mifepristone when used for management of abortion works via what mechanism? ...

    Correct

    • Mifepristone when used for management of abortion works via what mechanism?

      Your Answer: Anti-progestogen

      Explanation:

      Mifepristone is a prostaglandin antagonist. It acts as a competitive inhibitor of the receptor.

    • This question is part of the following fields:

      • Clinical Management
      11.9
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  • Question 32 - Regarding uterine fibroids, which of the following statements is false? ...

    Correct

    • Regarding uterine fibroids, which of the following statements is false?

      Your Answer: The risk of fibroids is increased by pregnancy

      Explanation:

      Fibroids are a common gynaecological condition found in many women above the age of 35. They are however uncommon before puberty. They are most common in black women vs white women, and its prevalence increases from puberty to menopause. Risk factors for fibroids include increasing age, obesity and infertility. Protective factors, on the other hand, include pregnancy, as the risk of fibroids decreases with increasing numbers of pregnancies.

    • This question is part of the following fields:

      • Clinical Management
      14.3
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  • Question 33 - Which species of candida is the most common cause of genital candida infection...

    Correct

    • Which species of candida is the most common cause of genital candida infection in pregnancy?

      Your Answer: Candida albicans

      Explanation:

      Vulvovaginal candidiasis is the most common genital infection and it is caused by candida albicans in 80-92% of the cases. Other non albicans species include C.tropicalis, C.glabrata, C.krusei and C.parapsilosis. 20% of women of childbearing age are asymptotic colonisers of Candida species as part of their normal vaginal flora. This increases to 40% in pregnancy.

    • This question is part of the following fields:

      • Clinical Management
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  • Question 34 - A 77 year old woman undergoes staging investigations for endometrial carcinoma. This shows...

    Incorrect

    • A 77 year old woman undergoes staging investigations for endometrial carcinoma. This shows invasion of the inguinal lymph nodes. What is this patients 5-year survival?

      Your Answer: 5%

      Correct Answer: 15%

      Explanation:

      Lymph node involvement means that the carcinoma is stage 4. The 5 year survival of stage 4 endometrial carcinoma is 16%.

    • This question is part of the following fields:

      • Clinical Management
      15.1
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  • Question 35 - A 32 year old women who is 25 weeks pregnant presents with vaginal...

    Incorrect

    • A 32 year old women who is 25 weeks pregnant presents with vaginal bleeding and cramping lower abdominal pain. On examination the cervix is closed. Fetal cardiac activity is noted on ultrasound. What is the likely diagnosis?

      Your Answer: Inevitable Miscarriage

      Correct Answer: Antepartum Haemorrhage

      Explanation:

      Antepartum haemorrhage (APH) is defined as bleeding from or in to the genital tract, occurring from 24+0 weeks of pregnancy and prior to the birth of the baby.

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      • Clinical Management
      3.1
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  • Question 36 - Renal cell carcinoma is associated with which type of metastasis? ...

    Incorrect

    • Renal cell carcinoma is associated with which type of metastasis?

      Your Answer: Lymphatic

      Correct Answer: Haematogenous

      Explanation:

      Most carcinomas spread primarily via lymphatic invasion. Renal cell is the exception spreading via the bloodstream.

    • This question is part of the following fields:

      • Clinical Management
      16.1
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  • Question 37 - A 32 year old woman who is 14 weeks pregnant presents to the...

    Incorrect

    • A 32 year old woman who is 14 weeks pregnant presents to the clinic with yellow, frothy vaginal discharge and vaginal soreness. Trichomoniasis is confirmed after microscopy on a wet smear. Which of the following is the most appropriate treatment?

      Your Answer: Amoxicillin 1g TDS 14 days

      Correct Answer: Metronidazole 400mg TDS 7 days

      Explanation:

      Trichomoniasis is considered a sexually transmitted infection found both in men and women caused by the flagellate protozoan Trichomonas vaginalis. The organism is mainly found in the vagina and the urethra. Though many infected women can be asymptomatic, they can also present with yellow frothy vaginal discharge, itching and vaginitis, dysuria or an offensive odour.

      For the diagnosis of t. vaginalis in women, a swab is taken from the posterior fornix during speculum examination and the flagellates are detected under light-field microscopy.

      The recommended treatment for t. vaginalis during pregnancy and breastfeeding is 400-500mg of metronidazole twice daily for 5 -7 days. High dose metronidazole as a 2g single dose tablet is not advised during pregnancy. All sexual partners should also be treated, and screening for other STIs should be carried out.

    • This question is part of the following fields:

      • Clinical Management
      4
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  • Question 38 - Which organism is the most common cause of puerperal sepsis? ...

    Incorrect

    • Which organism is the most common cause of puerperal sepsis?

      Your Answer: Gardnerella vaginalis

      Correct Answer: Group A Streptococcus

      Explanation:

      Puerperal sepsis is defined as sepsis occurring after birth until 6 weeks postnatal. The most common cause of puerperal sepsis is Group A streptococcus. Until 1937, puerperal sepsis was the major cause of maternal mortality. The discovery of sulphonamides in 1935 and the simultaneous reduction in the virulence of the haemolytic streptococcus resulted in a dramatic fall in maternal mortality.

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      • Clinical Management
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  • Question 39 - According to the RCOG Green-top guidelines on prevention and management of post-partum haemorrhage...

    Incorrect

    • According to the RCOG Green-top guidelines on prevention and management of post-partum haemorrhage (PPH) which of the following statements is true?

      Your Answer: Misoprostol is equally as effective as Oxytocin in PPH prevention

      Correct Answer: For women delivering by caesarean section, Oxytocin 5 iu by slow IV injection should be used

      Explanation:

      Misoprostol is not as effective as oxytocin but may be used if Oxytocin is not available e.g. home birth Recommended doses of Oxytocin For vaginal deliveries: 5 iu or 10 iu by intramuscular injection. For C-section: 5 iu by IV injection

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      • Clinical Management
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  • Question 40 - You are discussing a planned Caesarean Section (CS) with a patient. Which of...

    Incorrect

    • You are discussing a planned Caesarean Section (CS) with a patient. Which of the following risks is reduced with CS?

      Your Answer: Endometritis

      Correct Answer: Early postpartum haemorrhage

      Explanation:

      There are many different reasons for performing a delivery by Caesarean section. The four major indications accounting for greater than 70 per cent of operations are: 1. previous Caesarean section 2. dystocia 3. malpresentation 4. suspected acute fetal compromise. Other indications, such as multifetal pregnancy, abruptio placenta, placenta praevia, fetal disease and maternal disease are less common. The chances of early postpartum haemorrhage are greatly reduced in C-section deliveries.

    • This question is part of the following fields:

      • Clinical Management
      3.8
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  • Question 41 - Choriocarcinoma is associated with which type of metastasis? ...

    Correct

    • Choriocarcinoma is associated with which type of metastasis?

      Your Answer: Haematogenous

      Explanation:

      Choriocarcinoma spreads hematogenously.

    • This question is part of the following fields:

      • Clinical Management
      8.6
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  • Question 42 - What percentage of infants will have permanent neurological dysfunction as a result of...

    Incorrect

    • What percentage of infants will have permanent neurological dysfunction as a result of brachial plexus injury secondary to shoulder dystocia?

      Your Answer: 35%

      Correct Answer:

      Explanation:

      Shoulder dystocia occurs when the anterior or posterior fetal shoulder impacts on the maternal symphysis or sacrum and may require additional manevours to release the shoulders after gentle downward traction has failed. The most common injury that can occur, is to the brachial plexus due to lateral flexion of the head during traction. This may cause a neurological disability, Erb’s Palsy ( injury to C5 and C6 of the brachial plexus) in which there is a less than 10% chance that this injury would be permanent.

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      • Clinical Management
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  • Question 43 - The midwife asks for your advice about a 33 year old woman who...

    Incorrect

    • The midwife asks for your advice about a 33 year old woman who she has just seen at her booking appointment. The patient had an uncomplicated pregnancy 10 years ago. This is her second pregnancy. There is no significant personal or family history. On examination the patients blood pressure is 120/75, BMI 32.5kg/m2. The midwife asks your advice on testing for gestational diabetes. What would you advise?

      Your Answer: Fasting glucose at 16-18 weeks

      Correct Answer: OGTT at 24-28 weeks

      Explanation:

      Gestational diabetes (GDM) occurs in 2–9 per cent of all pregnancies. Screening for diabetes in pregnancy can be justify ed to diagnose previously unrecognized cases of pre-existing diabetes and to identify a group of women who are at risk of developing NIDDM later in life. No single screening test has been shown to be perfect in terms of high sensitivity and specific city for gestational diabetes. Urinary glucose is unreliable, and most screening tests now rely on blood glucose estimation, with an oral glucose tolerance test commonly used. The aim of glucose control is to keep fasting levels between 3.5 and 5.5 mmol/L and postprandial levels 7.1 mmol/L, with insulin treatment usually indicated outside these ranges.

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      • Clinical Management
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  • Question 44 - A 20 year old patient attends clinic for a medical abortion at 12...

    Correct

    • A 20 year old patient attends clinic for a medical abortion at 12 weeks gestation. She has no known drug allergies and her STI screen was negative. What drug should she be prescribed as antibiotic prophylaxis?

      Your Answer: Metronidazole 1g PR stat dose

      Explanation:

      According to the Royal College of Obstetrics and Gynaecology guidelines for abortion care it advises dual antibiotic regimes for antibiotic prophylaxis.
      Metronidazole 1g per rectum or 800 mg orally can be given before or at the time of the abortion in women who have tested negative for Chlamydia trachomatis infection.

      Alternatively, Doxycycline (100mg oral, twice daily for 7 days) or Azithromycin 1g stat doses should be given in addition to metronidazole to be effective against Chlamydia trachomatis anaerobes.

    • This question is part of the following fields:

      • Clinical Management
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  • Question 45 - A 36 year old women attends clinic following laparotomy and unilateral oophorectomy. The...

    Correct

    • A 36 year old women attends clinic following laparotomy and unilateral oophorectomy. The histology shows Psammoma bodies. What type of tumour would this be consistent with?

      Your Answer: Serous

      Explanation:

      Serous tumours of the ovaries are large, cystic and spherical to ovoid in shape. They can be benign or malignant. Malignant tumours are usually nodular with irregularities in the surface where the tumour penetrates into the serosa. Psammoma bodies are a histological identification for these tumours which appear in the tips of the papillae.

    • This question is part of the following fields:

      • Clinical Management
      6.7
      Seconds
  • Question 46 - Regarding menstruation, which of the following is the maximum normal blood loss? ...

    Incorrect

    • Regarding menstruation, which of the following is the maximum normal blood loss?

      Your Answer: 60-65ml

      Correct Answer: 80-85ml

      Explanation:

      Most women lose about 35-40 ml of blood on average during each menstrual cycle. The maximum amount of blood loss is 80 ml after which blood loss of more than 80 ml is defined as heavy menstrual bleeding, formerly known as menorrhagia.

    • This question is part of the following fields:

      • Clinical Management
      4.1
      Seconds
  • Question 47 - What is the most common cause of sepsis in the puerperium? ...

    Correct

    • What is the most common cause of sepsis in the puerperium?

      Your Answer: Endometritis

      Explanation:

      Significant puerperal pyrexia is defined as a temperature of 38ÂșC or higher on any two of the first 10 days postpartum, exclusive of the first 24 hours. A mixed flora normally colonizes the vagina with low virulence. Puerperal infection is usually polymicrobial and involves contaminants from the bowel that colonize the perineum and lower genital tract. Following delivery, natural barriers to infection are temporarily removed and therefore organisms with a pathogenic potential can ascend from the lower genital tract into the uterine cavity. Placental separation exposes a large raw area equivalent to an open wound, and retained products of conception and blood clots within the uterus can provide an excellent culture medium for infection.

    • This question is part of the following fields:

      • Clinical Management
      8.4
      Seconds
  • Question 48 - A baby with shoulder dystocia suffers a brachial plexus injury. The mother asks...

    Incorrect

    • A baby with shoulder dystocia suffers a brachial plexus injury. The mother asks you if this will be permanent. What percentage of babies will have permanent neurological dysfunction as a result of brachial plexus injury secondary to shoulder dystocia?

      Your Answer: <10%

      Correct Answer:

      Explanation:

      of cases there is no permanent neurological disability. Shoulder dystocia is the most common cause of Erb’s palsy (Erb-Duchenne palsy) where there is injury to C5 and C6 of the brachial plexus (C5 to T1)

    • This question is part of the following fields:

      • Clinical Management
      5
      Seconds
  • Question 49 - During pregnancy which hormone(s) inhibit lactogenesis? ...

    Incorrect

    • During pregnancy which hormone(s) inhibit lactogenesis?

      Your Answer: Prolactin and hPL (human Placental Lactogen)

      Correct Answer: Oestrogen and Progesterone

      Explanation:

      Prolactin levels rise steadily during pregnancy during which time it promotes mammary growth (along with the other hormones mentioned below). Oestrogen and progesterone inhibit lactogenesis and it is only with the loss of these placental steroid hormones at term that Prolactin exhibits its lactogenic effect.

    • This question is part of the following fields:

      • Clinical Management
      4.5
      Seconds
  • Question 50 - In patients with endometriosis what is the infertility rate? ...

    Incorrect

    • In patients with endometriosis what is the infertility rate?

      Your Answer:

      Correct Answer: 40%

      Explanation:

      Around 30-40% of women affected by this condition complain of difficulty in conceiving.

    • This question is part of the following fields:

      • Clinical Management
      0
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