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  • Question 1 - Regarding the formation of CSF, which of the following is true? ...

    Incorrect

    • Regarding the formation of CSF, which of the following is true?

      Your Answer: Brain interstitial fluid and CSF do not communicate freely

      Correct Answer: Its composition resembles that of brain ECF

      Explanation:

      In normal adults CSF volume is around 125ml to 150ml. Turnover of entire volume of cerebrospinal fluid a day is about 3 to 4 times a day. Composition of CSF is similar to that of plasma except that CSF is nearly protein-free compared with plasma and has a different electrolyte level. About 80% of CSF is produced by the choroid plexus. It is also produced by a single layer of column shaped ependymal cells. The composition and rate of CSF generation depends on several factors and is influenced by hormones and the content and pressure of blood and CSF.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      35.4
      Seconds

  • Question 2 - Which neuron secretes glutamate as its neurotransmitter? ...

    Incorrect

    • Which neuron secretes glutamate as its neurotransmitter?

      Your Answer: Golgi

      Correct Answer: A delta and C pain fibers

      Explanation:

      A delta and C fibers use glutamate as their primary neurotransmitter where it acts as a fast acting localized neurotransmitter.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      9.5
      Seconds

  • Question 3 - The superior orbital fissure is the site of entry/exit for which of the...

    Incorrect

    • The superior orbital fissure is the site of entry/exit for which of the following group of nerves?

      Your Answer: CN II, III, IV, VI

      Correct Answer: CN III, IV, V1, VI

      Explanation:

      The superior and inferior divisions of oculomotor nerve (III), trochlear nerve (IV), lacrimal, frontal and nasociliary branches of ophthalmic V1 and the abducens nerve (VI)

    • This question is part of the following fields:

      • Medicine
      • Neurology
      40.5
      Seconds

  • Question 4 - Which neurotransmitter is released from the postganglionic fibers in the sympathetic division? ...

    Incorrect

    • Which neurotransmitter is released from the postganglionic fibers in the sympathetic division?

      Your Answer: Acetylcholine

      Correct Answer: Noradrenalin

      Explanation:

      Noradrenalin Is the neurotransmitter that is released from the postganglionic fibers of the sympathetic division. It is stored in granules at the sympathetic knobs. It Is a methyl derivative.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      12.8
      Seconds

  • Question 5 - Where is the aqueous humor normally reabsorbed? ...

    Incorrect

    • Where is the aqueous humor normally reabsorbed?

      Your Answer:

      Correct Answer: Canal of schlemm

      Explanation:

      Aqueous humor is a clear protein free fluid secreted by the ciliary body, it travels to the anterior chamber through the pupil and is absorbed through a network of trabeculae into the canal of schlemm

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 6 - Cranial nerves VI, VII, VIII enter/exit the base of the brain at the:...

    Incorrect

    • Cranial nerves VI, VII, VIII enter/exit the base of the brain at the:

      Your Answer:

      Correct Answer: Ponto-medullary junction

      Explanation:

      Cranial nerves III, IV and V exit from the pons, VI, VII, VIII exit from the pontomedullary junction and cranial nerve IX, X, XI, XII exit from the medulla.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 7 - The thalamic main input from the cortex is via which tracts? ...

    Incorrect

    • The thalamic main input from the cortex is via which tracts?

      Your Answer:

      Correct Answer: Thalamocortical pathway

      Explanation:

      The thalamus is connected to cerebral cortex via the thalamocortical radiation.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 8 - The Afferent neuron that supplies all sensory elements of the muscle spindle is...

    Incorrect

    • The Afferent neuron that supplies all sensory elements of the muscle spindle is what type of sensory neuron?

      Your Answer:

      Correct Answer: Ia

      Explanation:

      Muscle spindle is supplied by both sensory and motor nerves. Sensory supply is Type Ia fibers whereas motor supply is gamma motor neurone.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 9 - Choose the correct answer: The cerebrocerebellum… ...

    Incorrect

    • Choose the correct answer: The cerebrocerebellum…

      Your Answer:

      Correct Answer: All options are correct

      Explanation:

      Cerebrocerebellum is comprised of two lateral regions, the cerebellar hemispheres and communicates with the cerebral cortex. It is principally responsible for controlling coordination of movement. Three fiber bundles carry the input and output of the cerebellum. There are three cerebellar peduncles with different connections and functions. The three are mainly, superior, middle and inferior. The superior cerebellar peduncle is also known as the “Brachium conjunctivum”. It predominantly contains efferent fibers from the cerebellar nuclei, as well as some afferents from the spinocerebellar tract. The efferent pathways include cerebellorubral, dentatothalamic, and fastigioreticular fibers. These are tracts projecting from the deep cerebellar nuclei to the thalamus and red nucleus. The middle cerebellar peduncle connects to the pontine nucleus and the dorsal spinocerebellar tracts run through the superior cerebellar peduncle

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 10 - Activation of the cool receptor (CMR-1), causes: ...

    Incorrect

    • Activation of the cool receptor (CMR-1), causes:

      Your Answer:

      Correct Answer: Influx of Ca++ & Na+

      Explanation:

      Cold and Menthol receptor 1 (CMR1) is a protein that in humans is encoded by TRPM8 gene. It is an ion channel which upon activation causes the influx of Na+ and Ca++ ions into the cell that leads to the depolarization and generation of an action potential.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 11 - In the olfactory pathway: Mitral cells project to five regions of the olfactory...

    Incorrect

    • In the olfactory pathway: Mitral cells project to five regions of the olfactory cortex. Which one of the following is not one of the five regions?

      Your Answer:

      Correct Answer: Posterior olfactory nucleus

      Explanation:

      The olfactory system contains peripheral and central divisions which are connected by transduction structures. Peripheral division consists mainly of the nostrils, ethmoid bone, nasal cavity, and the olfactory epithelium. Olfactory neurons are receptor cells in the epithelium that detect odour molecules dissolved in the mucus and transmit information about the odour to the brain in a process called sensory transduction. Olfactory nerves and fibers transmit information about odours from the peripheral olfactory system to the central olfactory system of the brain. The main olfactory bulb transmits pulses to both mitral and tufted cells, which help determine odour concentration. These cells also note differences between highly similar odours and use that data to aid in later recognition. The cells are different with the mitral having low firing-rates and being easily inhibited by neighbouring cells, while tufted have high rates of firing and are more difficult to inhibit. The uncus houses the olfactory cortex which includes the piriform cortex, amygdala, olfactory tubercle, and para-hippocampal gyrus. Entorhinal cortex is an area of middle temporal lobe that has connection with the para-hippocampal gyrus.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 12 - Which of the following is not innervated by the parasympathetic nerve supply? ...

    Incorrect

    • Which of the following is not innervated by the parasympathetic nerve supply?

      Your Answer:

      Correct Answer: Radial muscle of iris

      Explanation:

      The sphincter pupillae is supplied by the parasympathetic fibers from the Edinger Westphal nucleus of the oculomotor nerve. The dilator pupillae (radial muscle) is supplied by the postganglionic fibers of the superior cervical sympathetic ganglion. The parasympathetic nerve supply to the salivary glands originate in the parasympathetic nucleus of the facial nerve (superior salivatory nucleus) and the glossopharyngeal nerve (inferior salivatory nucleus). The parasympathetic preganglionic fibers originate in the dorsal nucleus of the vagus nerve and descend into the thorax in the vagus nerve. The fibers terminate by synapsing with postganglionic neurons in the cardiac plexuses. Postganglionic fibers terminate on the sinoatrial and atrioventricular nodes and on the coronary arteries Parasympathetic supply to the stomach is via the vagus nerve.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 13 - The brainstem reticular formation, consists of which important control system responsible for consciousness...

    Incorrect

    • The brainstem reticular formation, consists of which important control system responsible for consciousness and sleep?

      Your Answer:

      Correct Answer: RAS reticular activating system

      Explanation:

      The reticular formation is a set of interconnected nuclei that are located along the brainstem. Reticular activating system (RAS) is a set of connected nuclei in the brain that is responsible for regulating wakefulness and sleep wake transitions and is the most influential component in the reticular formation.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 14 - In the basal ganglia, the Lentiform nucleus is formed by which two nuclei?...

    Incorrect

    • In the basal ganglia, the Lentiform nucleus is formed by which two nuclei?

      Your Answer:

      Correct Answer: Putamen and Globus pallidus

      Explanation:

      The Basal Ganglia are composed of the following structures: Caudate, putamen, Globus pallidus, subthalamic nucleus and substantia nigra.

      The Lentiform nucleus is a biconvex structure located within the basal ganglia of the brain. It is composed of two nuclei:

      1. Putamen: This is the outer part of the Lentiform nucleus and is involved in regulating movements and various types of learning.
      2. Globus pallidus: This is the inner part of the Lentiform nucleus and is divided into two segments: the external segment (GPe) and the internal segment (GPi). It plays a key role in the regulation of voluntary movement.

      These two structures together form the Lentiform nucleus, which is an integral part of the basal ganglia system involved in motor control.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 15 - The thalamus is a large collection of neuronal groups within the diencephalons which...

    Incorrect

    • The thalamus is a large collection of neuronal groups within the diencephalons which participates in:

      Your Answer:

      Correct Answer: Sensory, motor and limbic

      Explanation:

      The thalamus has multiple functions. It is the relay station for every sensory system (except olfactory, regulates the sleep-wake cycle and consciousness and also relays motor information.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 16 - Where are the cell bodies of preganglionic neurons located? ...

    Incorrect

    • Where are the cell bodies of preganglionic neurons located?

      Your Answer:

      Correct Answer: Lateral column

      Explanation:

      The cell bodies of the preganglionic neurons are located in the lateral grey column of the spinal cord and in the motor nuclei of the 3rd, 7th, 9th and 10th cranial nerves.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 17 - Which serotonergic receptor is associated with vomiting? ...

    Incorrect

    • Which serotonergic receptor is associated with vomiting?

      Your Answer:

      Correct Answer: 5ht3

      Explanation:

      5ht3 is a receptor strongly associated with vomiting, present in vagal afferents, the solitary tract nucleus (STN), and the area posterior. For this reason, 5ht3 antagonists are commonly used as antiemetic drugs. They include ondansetron, tropisetron, and granisetron.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 18 - The brainstem contains which of the following structures? ...

    Incorrect

    • The brainstem contains which of the following structures?

      Your Answer:

      Correct Answer: The midbrain, pons and medulla

      Explanation:

      Brain stem is the base of the brain that connects the brain to the spinal cord. It consists of the mid brain, pons and medulla oblongata.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 19 - Which of the following receptors are found in the liver? ...

    Incorrect

    • Which of the following receptors are found in the liver?

      Your Answer:

      Correct Answer: α1, β2

      Explanation:

      Liver consists of the sympathetic Alpha 1 and beta 2 receptors.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 20 - What landmark divides the frontal and parietal lobes? ...

    Incorrect

    • What landmark divides the frontal and parietal lobes?

      Your Answer:

      Correct Answer: Central sulcus

      Explanation:

      The central sulcus divides the frontal lobe from the parietal lobe. It contains the motor cells for the movement function of the body.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 21 - The choroid plexus: ...

    Incorrect

    • The choroid plexus:

      Your Answer:

      Correct Answer: All are true

      Explanation:

      The choroid plexus is a vascular structure found in all cerebral ventricles. The functional unit of the choroid plexus, composed of a capillary, enveloped by a layer of differentiated ependymal epithelium. Unlike the capillaries that form the blood-brain barrier, choroid plexus capillaries are fenestrated and have no tight junctions. The endothelium, therefore, does not form a barrier to the movement of small molecules. Instead, the blood-CSF barrier at the choroid plexus is formed by the epithelial cells and the tight junctions that link them.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 22 - Visual pathways - Choose the true statement: ...

    Incorrect

    • Visual pathways - Choose the true statement:

      Your Answer:

      Correct Answer: The lateral geniculate nucleus, magnocellular & parvocellular pathways project to the primary visual cortex

      Explanation:

      The optic chiasm is made by the decussation of optic fibers on the nasal side. The magnocellular pathway carries signals for detection of movement. The parvocellular pathway carries cells for detection of shape, size, colour and clarity. The lateral geniculate nucleus (LGN) is the relay centre in the thalamus for he visual pathway. It has layers of magnocellular cells and parvocellular cells that are interleaved with layers of koniocellular cells. The LGN is the main central connection for the optic nerve to the occipital lobe, particularly the primary visual cortex.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 23 - Afferent A δ fibers from nociceptors terminate primarily on neurons in which lamina:...

    Incorrect

    • Afferent A δ fibers from nociceptors terminate primarily on neurons in which lamina:

      Your Answer:

      Correct Answer: I and V

      Explanation:

      Nociceptors are receptors of pain sensation. There are 2 primary afferent/sensory pain fibers which transmit impulses from the receptor to the CNS, specifically to the dorsal horn of the spinal cord. The two fibers are A δ and C fibers. The dorsal horn of the spinal cord is the relay centre for sensory information converging from the periphery. Grey matter of the dorsal horn is subdivided in to laminae based on cytoarchitecture. C fibers terminate in lamina II the substantia gelatinosa. A δ fibers terminate primarily in lamina I but some project more deeply to terminate in lamina V.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 24 - The reticular formation occupies which area of the brain? ...

    Incorrect

    • The reticular formation occupies which area of the brain?

      Your Answer:

      Correct Answer: Medulla and midbrain

      Explanation:

      The reticular formation is a set of interconnected nuclei that are located along the brainstem.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 25 - The pontine tegmentum as part of the midbrain, contains which cranial nerve nuclei?...

    Incorrect

    • The pontine tegmentum as part of the midbrain, contains which cranial nerve nuclei?

      Your Answer:

      Correct Answer: CN 5 to 8

      Explanation:

      The pontine tegmentum also known as dorsal pons is located within the brain stem. Several cranial nerve nuclei are located in the pontine tegmentum. The nuclei of CN V, CN VI, CN VII and CNVIII are located in the pontine tegmentum.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 26 - Cold receptors are likely to be active at the following temperatures except? ...

    Incorrect

    • Cold receptors are likely to be active at the following temperatures except?

      Your Answer:

      Correct Answer: 39 °C

      Explanation:

      Cold and Menthol receptor 1 (CMR1) is a protein that in humans is encoded by TRPM8 gene. It is primarily responsible for the detection of temperatures ranging from 8-28 C. It is an ion channel which upon activation causes the influx of Na+ and Ca+ ions into the cell that leads to the depolarization and generation of an action potential.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 27 - The parasympathetic function of the facial nerve is: ...

    Incorrect

    • The parasympathetic function of the facial nerve is:

      Your Answer:

      Correct Answer: Secretion of tears from lacrimal glands, secretion of saliva from the sublingual and submandibular salivary glands.

      Explanation:

      Facial nerve (Cranial Nerve VII) has both sensory and motor components so it is a mixed nerve. It carries axons of:General somatic afferent – to skin and the posterior earGeneral visceral efferent – which innervate sublingual, submandibular and lacrimal glands and the mucosa of the nasal cavity.General visceral afferent – provide sensation to soft palate and parts of the nasal cavity.Special visceral efferent – innervate muscles of facial expression and stapedius, the posterior belly of the digastric and the stylohyoid musclesSpecial visceral afferent – provide taste to the anterior two-thirds of the tongue via chorda tympani.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 28 - Concerning the sleep-wake cycle, Melatonin is secreted by which structure in the brain...

    Incorrect

    • Concerning the sleep-wake cycle, Melatonin is secreted by which structure in the brain following which environmental conditions?

      Your Answer:

      Correct Answer: Pineal gland, darkness

      Explanation:

      Melatonin is secreted by the pineal gland located in the midline attached to the posterior roof of the third ventricle in the brain. Melatonin affects circadian rhythm in the body or the sleep wake cycle. The precursor to melatonin is serotonin and the rate limiting enzyme that converts serotonin to melatonin is low during the day time and reaches its peak during the night.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 29 - In which cell would you find a Nissl body? ...

    Incorrect

    • In which cell would you find a Nissl body?

      Your Answer:

      Correct Answer: Bipolar neuron

      Explanation:

      Nissl bodies are the structures of protein synthesis in neurones. They are granular bodies of Rough Endoplasmic Reticulum and ribosomes. Astrocytes, Microglia, Schwann cell, oligodendrocytes are collectively known as glia or supporting cells of the nervous system.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

  • Question 30 - Which of the following tracts are involved in the control of vital functions?...

    Incorrect

    • Which of the following tracts are involved in the control of vital functions?

      Your Answer:

      Correct Answer: Reticulospinal

      Explanation:

      Reticulospinal tract pass down from the reticular formation of the mid brain, pons and medulla. It descends in the lateral white column. Both sets of fibers enter the anterior grey column and may facilitate or inhibit the gamma and alpha neurons. By this means the reticulospinal tract controls voluntary and reflex activities. It also contains the descending autonomic fiber, thus providing a pathway for the hypothalamus to control the sympathetic and parasympathetic pathways.

    • This question is part of the following fields:

      • Medicine
      • Neurology
      0
      Seconds

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