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  • Question 1 - You intend to suture a hand wound with plain 1 percent lidocaine.

    In 1...

    Incorrect

    • You intend to suture a hand wound with plain 1 percent lidocaine.

      In 1 mL of plain 1 percent lidocaine solution, how much lidocaine hydrochloride is there?

      Your Answer: 1 mg lidocaine hydrochloride

      Correct Answer: 10 mg lidocaine hydrochloride

      Explanation:

      10 mg of lidocaine hydrochloride is contained in each 1 mL of plain 1 percent lidocaine solution.

    • This question is part of the following fields:

      • Anaesthesia
      • Pharmacology
      22.9
      Seconds
  • Question 2 - As part of his angina treatment, a 68-year-old man is prescribed a beta...

    Correct

    • As part of his angina treatment, a 68-year-old man is prescribed a beta blocker. He starts having nightmares and has trouble sleeping soon after starting the beta-blocker.

      Which of the beta blockers listed below is the most likely to be in his system?

      Your Answer: Propranolol

      Explanation:

      The beta-adrenoceptors in the heart, peripheral vasculature, bronchi, pancreas, and liver are blocked by beta-adrenoceptor blocking drugs (beta blockers).

      Beta blockers come in a wide range of strengths, with the choice largely determined by the disease being treated and the patient’s unique circumstances. The intrinsic sympathomimetic activity, lipid solubility, duration of action, and cardioselectivity of beta blockers all differ.

      Some beta blockers are lipid (lipophilic) soluble, while others are water soluble (hydrophilic). Drugs that are more lipid-soluble are absorbed faster from the gut, undergo more first-pass metabolism, and are eliminated faster. They’re also more likely to get into the brain and cause central effects like insomnia and nightmares. Propranolol, pindolol, labetalol, and metoprolol are examples of lipid-soluble beta blockers. Beta blockers that are water-soluble are less likely to enter the brain and are more resistant to first-pass metabolism. They are excreted by the kidneys, and in renal impairment, dosage reduction is frequently required. Atenolol, nadolol, celiprolol, and sotalol are examples of water-soluble beta blockers.

    • This question is part of the following fields:

      • Cardiovascular Pharmacology
      • Pharmacology
      36.6
      Seconds
  • Question 3 - A 29 year old woman is unable to invert her foot after sustaining...

    Correct

    • A 29 year old woman is unable to invert her foot after sustaining an injury to her leg playing water-polo. Which of the following nerves are most likely damaged:

      Your Answer: Tibial and deep fibular nerve

      Explanation:

      Inversion of the foot is primarily produced by the tibialis anterior and the tibialis posterior muscles, innervated by the deep fibular nerve and the tibial nerve respectively.

    • This question is part of the following fields:

      • Anatomy
      • Lower Limb
      48.2
      Seconds
  • Question 4 - Regarding acute lymphoblastic leukaemia (ALL), which of the following statements is CORRECT: ...

    Incorrect

    • Regarding acute lymphoblastic leukaemia (ALL), which of the following statements is CORRECT:

      Your Answer: 85% of cases are of T-cell lineage.

      Correct Answer: ALL is the most common malignancy of childhood.

      Explanation:

      Acute lymphoblastic leukaemia (ALL) is caused by an accumulation of lymphoblasts in the bone marrow and is the most common malignancy of childhood. The incidence of ALL is highest at 3 – 7 years, with 75% of cases occurring before the age of 6. 85% of cases are of B-cell lineage. Haematological investigations reveal a normochromic normocytic anaemia with thrombocytopenia in most cases. The total white cell count may be decreased, normal or increased. The blood film typically shows a variable number of blast cells. The bone marrow is hypercellular with >20% blast cells.

    • This question is part of the following fields:

      • Haematology
      • Pathology
      40.1
      Seconds
  • Question 5 - Antidiuretic hormone (ADH) levels are found to be increased in a young lady with...

    Correct

    • Antidiuretic hormone (ADH) levels are found to be increased in a young lady with unexplained hyponatraemia.

      In a healthy patient under normal circumstances, in which of the following conditions would ADH not be released?

      Your Answer: Increased alcohol intake

      Explanation:

      Antidiuretic hormone (ADH) is produced in the hypothalamus’s supraoptic nucleus and then released into the blood via axonal projections from the hypothalamus to the posterior pituitary.

      It is carried down axonal extensions from the hypothalamus (the neurohypophysial capillaries) to the posterior pituitary, where it is kept until it is released, after being synthesized in the hypothalamus.
      The secretion of ADH from the posterior pituitary is regulated by numerous mechanisms:
      Increased plasma osmolality: Osmoreceptors in the hypothalamus detect an increase in osmolality and trigger ADH release.

      Hypovolaemia causes a drop in atrial pressure, which stretch receptors in the atrial walls and big veins detect (cardiopulmonary baroreceptors). ADH release is generally inhibited by atrial receptor firing, but when the atrial receptors are stretched, the firing reduces and ADH release is promoted.

      Hypotension causes baroreceptor firing to diminish, resulting in increased sympathetic activity and ADH release.
      An increase in angiotensin II stimulates angiotensin II receptors in the hypothalamus, causing ADH production to increase.

      Nicotine, Sleep, Fright, and Exercise are some of the other elements that might cause ADH to be released.
      Alcohol (which partly explains the diuretic impact of alcohol) and elevated levels of ANP/BNP limit ADH release.

    • This question is part of the following fields:

      • Physiology
      • Renal Physiology
      73
      Seconds
  • Question 6 - Which of the following is NOT an advantage of a case-control study used...

    Correct

    • Which of the following is NOT an advantage of a case-control study used to identify past exposure to a risk factor in patients with a disease:

      Your Answer: Can directly measure absolute and relative risk of a disease

      Explanation:

      Advantages:relatively quickrelatively cheap and easy to performparticularly suitable for studying associations between an exposure and an outcome when the outcome is uncommon or if the outcome occurs decades after exposurea wide range of risk factors can be investigated in each studyDisadvantages:subject to recall biasunlike in a whole population study, absolute risk cannot be quantifiedtemporal relationship between exposure and outcome can be difficult to establishunsuitable for rare risk factorsprone to confounding

    • This question is part of the following fields:

      • Evidence Based Medicine
      • Study Methodology
      119.6
      Seconds
  • Question 7 - Which of the following anatomical structures is most likely the cause of oedema...

    Correct

    • Which of the following anatomical structures is most likely the cause of oedema and erythema of the arm in a patient who underwent modified radical mastectomy and radiotherapy?

      Your Answer: Axillary lymph nodes

      Explanation:

      Arm oedema is one of the sequelae after breast cancer surgery and radiation therapy. Arm oedema in the breast cancer patient is caused by interruption of the axillary lymphatic system by surgery or radiation therapy, which results in the accumulation of fluid in subcutaneous tissue in the arm, with decreased distensibility of tissue around the joints and increased weight of the extremity. Chronic inflammatory changes result in both subcutaneous and lymph vessel fibrosis.

    • This question is part of the following fields:

      • Anatomy
      • Thorax
      60.8
      Seconds
  • Question 8 - Which of the following is considered the best source of information if a...

    Incorrect

    • Which of the following is considered the best source of information if a research on the national hospital MRSA rates is being done?

      Your Answer: Local Patient Administration System data

      Correct Answer: Hospital Episode Statistics

      Explanation:

      Hospital Episode Statistics (HES) is a data warehouse containing details of all admissions, outpatient appointments and A and E attendances at NHS hospitals in England.

      Each HES record contains a wide range of information about an individual patient admitted to an NHS hospital, including:
      – clinical information about diagnoses and operations
      – patient information, such as age group, gender and ethnicity
      – administrative information, such as dates and methods of admission and discharge
      – geographical information such as where patients are treated and the area where they live

      Some benefits of HES include:
      – monitor trends and patterns in NHS hospital activity
      – assess effective delivery of care
      – support local service planning
      – reveal health trends over time
      – determine fair access to health care

    • This question is part of the following fields:

      • Evidence Based Medicine
      40.2
      Seconds
  • Question 9 - A 63 year old lady presents to ED with a persistent cough and...

    Incorrect

    • A 63 year old lady presents to ED with a persistent cough and red currant jelly sputum. She has a history of chronic alcohol abuse and has an X-ray which demonstrates a cavitating pneumonia. The most likely causative pathogen is:

      Your Answer: Staphylococcus aureus

      Correct Answer: Klebsiella pneumoniae

      Explanation:

      One of the results of Klebsiella pneumoniae is pneumonia that is usually a very severe infection. It is characterised by thick, bloody sputum (red currant jelly sputum), and is associated with complications like lung abscess, cavitation, necrosis, empyema and pleural effusions.

    • This question is part of the following fields:

      • Infections
      • Microbiology
      22.4
      Seconds
  • Question 10 - An 82-year-old woman was brought in an ambulance to the Emergency Department with...

    Correct

    • An 82-year-old woman was brought in an ambulance to the Emergency Department with a 1-hour history of left-sided weakness and dysphasia.

      A CT scan is performed, and primary intracerebral haemorrhage is excluded as a possible cause. She is prepared for thrombolysis when her blood pressure is recorded at 200/115 mmHg.

      Out of the following, which step would be the most appropriate as the next step in her management?

      Your Answer: Labetalol 10 mg IV

      Explanation:

      A patient suffering from acute ischemic stroke can commonly present with hypertensive emergencies. Thrombolytic therapy is contraindicated in a patient with:
      1. Systolic blood pressure greater than 185 mmHg
      2. Diastolic blood pressure greater than 110 mmHg

      But delaying thrombolytic therapy is associated with increased morbidity in patients with acute ischemic stroke.

      Managing high blood pressure in acute ischemic stroke requires a slower and more controlled reduction in BP. In the presence of an ischaemic stroke, rapid reduction of MAP can compromise blood flow, causing further ischemia and worsening of the neurological deficit.

      Intravenous labetalol is the agent of choice. The dose is 10 mg IV over 1-2 minutes. This dose can be repeated, or an infusion can be set up that runs at 2-8 mg/minute. Thrombolysis can be performed once the blood pressure is brought down to less than 180/105 mmHg.

      A nitrate infusion (for example, Isoket) can be used as an alternative in patients with contraindications to the use of beta-blockers (e.g., asthma, heart block, cardiac failure).

    • This question is part of the following fields:

      • Cardiovascular Pharmacology
      • Pharmacology
      78.9
      Seconds
  • Question 11 - Gastric emptying is increased by all of the following EXCEPT for: ...

    Incorrect

    • Gastric emptying is increased by all of the following EXCEPT for:

      Your Answer: Parasympathetic stimulation

      Correct Answer: Secretin

      Explanation:

      Gastric emptying is increased by:
      Distension of the pyloric antrum
      A fall in the pH of chyme in the stomach
      Parasympathetic stimulation (via vagus)
      Gastrin
      The hormones secretin, cholecystokinin and gastric inhibitory polypeptide (GIP) inhibit gastric emptying.

    • This question is part of the following fields:

      • Gastrointestinal
      • Physiology
      21.1
      Seconds
  • Question 12 - A 60-year-old man presents with marked breathlessness. He has with a history of...

    Correct

    • A 60-year-old man presents with marked breathlessness. He has with a history of ischaemic heart disease. On examination, there is coarse bibasal crackles, marked peripheral oedema and chest X-ray taken is consistent with severe pulmonary oedema. RR is 28 per minute.

      Which receptor is responsible for detecting pulmonary oedema and the subsequent increase in respiratory rate?

      Your Answer: Juxtacapillary receptors

      Explanation:

      Pulmonary oedema causes stimulation of the Juxtacapillary receptors (J receptors) leading to a reflex increase in breathing rate. These receptors are also thought to be involved in the sensation of dyspnoea. The J receptors are sensory cells and are located within the alveolar walls in juxtaposition to the pulmonary capillaries.

      Aortic baroreceptor are involved in detecting blood pressure

      Central chemoreceptors detect changes in CO2 and hydrogen ion within the brain

      Atrial volume receptors regulate plasma volume

    • This question is part of the following fields:

      • Physiology
      • Respiratory Physiology
      18.8
      Seconds
  • Question 13 - Which of the following features of cell damage tends to be reversible: ...

    Correct

    • Which of the following features of cell damage tends to be reversible:

      Your Answer: Swelling of endoplasmic reticulum and some mitochondria

      Explanation:

      Features of cell damage that tend to be reversible include: swelling of endoplasmic reticulum and some mitochondrialoss of ribosomescell stress response
      Features of cell damage that tend to be irreversible include: loss of nucleolus, no ribosomes, swelling of all mitochondria, nuclear condensation, membrane blebs and holes, lysosome rupture, fragmentation of all inner membranes, nuclear breakup

    • This question is part of the following fields:

      • Inflammatory Responses
      • Pathology
      51.5
      Seconds
  • Question 14 - A 38-year-old taxi driver sustained blunt force trauma to his anterior chest from...

    Correct

    • A 38-year-old taxi driver sustained blunt force trauma to his anterior chest from the steering wheel of his car after falling asleep while driving headlong into an oncoming HGV lorry. Bruising around his sternum was observed, which appears to be the central point of impact.

      Which of the following structures is most likely injured by the blunt force trauma?

      Your Answer: Right ventricle

      Explanation:

      In its typical anatomical orientation, the heart has 5 surfaces formed by different internal divisions of the heart:

      Anterior (or sternocostal) – Right ventricle
      Posterior (or base) – Left atrium
      Inferior (or diaphragmatic) – Left and right ventricles
      Right pulmonary – Right atrium
      Left pulmonary – Left ventricle

    • This question is part of the following fields:

      • Anatomy
      • Thorax
      29.8
      Seconds
  • Question 15 - A 40-year-old woman was rushed to the Emergency Department due to an anaphylactic...

    Incorrect

    • A 40-year-old woman was rushed to the Emergency Department due to an anaphylactic reaction after being stung by a bee. She responded well to initial treatment but developed anaphylactic symptoms after 6 hours. Her symptoms were resolved after a further dose of adrenaline. Her family threatened legal action as they thought she had not received adequate treatment but withdrew their accusation after the attending physician explained that the woman had suffered a biphasic reaction.

      What is the approximate percentage of people who suffer this type of reaction?

      Your Answer: 10%

      Correct Answer: 20%

      Explanation:

      Anaphylactic reactions are Type 1 hypersensitivity reactions IgE-mediated and can be potentially life-threatening if not treated promptly. There are four well-recognized patterns of anaphylaxis:
      1) Uniphasic
      2) Biphasic
      3) Protracted
      4) Refractory

      Biphasic reactions occur in 20% of the population, although their mechanism is poorly understood. The symptoms of anaphylaxis recur within 4-6 hours, although they may also recur up to 72 hours later. All patients discharged from the hospital after an anaphylactic shock must:
      1) Be warned to return to the hospital immediately if symptoms recur
      2) Have a treatment plan in place
      3) Have a follow-up appointment
      4) Be considered for an adrenaline auto-injector
      5) Referred to an allergy clinic

    • This question is part of the following fields:

      • General Pathology
      • Pathology
      67.8
      Seconds
  • Question 16 - Beta cells of the endocrine pancreas produce which of the following hormones: ...

    Correct

    • Beta cells of the endocrine pancreas produce which of the following hormones:

      Your Answer: Insulin

      Explanation:

      Insulin is produced by beta cells, located centrally within the islets of Langerhans, in the endocrine tissues of the pancreas. Insulin is a polypeptide hormone consisting of two short chains (A and B) linked by disulphide bonds. Proinsulin is synthesised as a single-chain peptide. Within storage granules, a connecting peptide (C peptide) is removed by proteases to yield insulin. Insulin release is stimulated initially during eating by the parasympathetic nervous system and gut hormones such as secretin, but most output is driven by the rise in plasma glucose concentration that occurs after a meal. The effects of insulin are mediated by the receptor tyrosine kinase.

    • This question is part of the following fields:

      • Endocrine
      • Physiology
      5.1
      Seconds
  • Question 17 - When a child has mumps, how long should he or she be off...

    Incorrect

    • When a child has mumps, how long should he or she be off from school?

      Your Answer: 5 days after swelling has resolved

      Correct Answer: 5 days from onset of swelling

      Explanation:

      To avoid the spread of infection, infected patients should be isolated. Patients should avoid going to school, childcare, or job for five days after the swelling has occurred.

    • This question is part of the following fields:

      • Microbiology
      • Pathogens
      27.1
      Seconds
  • Question 18 - The most common site of ectopic pregnancy is? ...

    Correct

    • The most common site of ectopic pregnancy is?

      Your Answer: Ampulla of Fallopian tube

      Explanation:

      Nearly 95% of ectopic pregnancies are implanted in the various segments of the fallopian tube and give rise to fimbrial, ampullary, isthmic, or interstitial tubal pregnancies. The ampulla is the most frequent site, followed by the isthmus. The remaining 5% of non tubal ectopic pregnancies implant in the ovary, peritoneal cavity, cervix, or prior caesarean scar.

    • This question is part of the following fields:

      • Abdomen And Pelvis
      • Anatomy
      5.1
      Seconds
  • Question 19 - A 54-year-old man who is acutely unwell has his blood sent for test...

    Correct

    • A 54-year-old man who is acutely unwell has his blood sent for test and the results come back with a CRP of 115.

      Which of these statements about C-reactive protein is FALSE?

      Your Answer: It is produced in the bone marrow

      Explanation:

      C-reactive protein(CRP) is synthesized in the liver in response to increased interleukin-6 (IL-6) secretion by macrophages and T-cells.
      Some conditions that cause CRP levels to a rise include: bacterial infection, fungal infection, severe trauma, autoimmune disease, Organ tissue necrosis, malignancy and surgery.

      It is useful in the clinical setting as a marker of inflammatory activity and can be used to monitor infections.

      CRP levels start to rise 4-6 hours after an inflammatory trigger and reaches peak levels at 36-50 hours.

      In the absence of a disease process, the normal plasma concentration is less than 5 mg/l.

      CRP is useful for monitoring inflammatory conditions (e.g. rheumatoid arthritis and malignancy), can be used as a prognostic marker in acute pancreatitis, and serial measurement can be used to recognize the onset of nosocomial infections in the intensive care settling.

    • This question is part of the following fields:

      • General Pathology
      • Pathology
      57.3
      Seconds
  • Question 20 - A 79-year-old male had a humeral shaft fracture during a road traffic accident...

    Incorrect

    • A 79-year-old male had a humeral shaft fracture during a road traffic accident and is being followed up in a fracture clinic. He complains of inability to use the limb 6 months after the injury. X-rays of that arm shows non union of his fracture.

      All the following are responsible for this non-union EXCEPT?

      Your Answer: Tissue interposed between fracture ends

      Correct Answer: Osteoporosis

      Explanation:

      An imbalance between bone resorption and formation is Osteoporosis. In normal bone, formation and resorption are roughly equal, and the density of bone matrix remains constant but there is more resorption in osteoporosis and the matrix density reduces and bones become weaker. Fractures are more likely to occur but healing is unaffected.

      Non-union of a fracture occurs when the two sides of a fracture fail to unite after 6 months. Causes include: infection, movement at the fracture site, avascular necrosis, tissue interposed between the fracture and gross misalignment.

    • This question is part of the following fields:

      • General Pathology
      • Pathology
      25
      Seconds
  • Question 21 - A 60-year-old man diagnosed with chronic kidney disease has an elevated creatinine level...

    Incorrect

    • A 60-year-old man diagnosed with chronic kidney disease has an elevated creatinine level and a reduced glomerular filtration rate (GFR).

      Which statement concerning glomerular filtration is true?

      Your Answer: The Cockcroft and Gault formula underestimates creatinine in obese patients

      Correct Answer: Creatinine is freely filtered at the glomerulus

      Explanation:

      Glomerular filtration is a passive process. It depends on the net hydrostatic pressure across the glomerular capillaries, the oncotic pressure, and the intrinsic permeability of the glomerulus.

      The mean values for glomerular filtration rate (GFR) in young adults are 130 ml/min/1.73m2 in males and 120 ml/min/1.73m2in females.

      The GFR declines with age after the age of 40 at a rate of approximately 1 ml/min/year.

      The Cockcroft and Gault formula overestimates creatinine in obese patients. This is because their endogenous creatinine production is less than that predicted by overall body weight.

      Creatinine is used in the estimation of GFR because it is naturally produced by muscle breakdown, not toxic, not produced by the kidney, freely filtered at the glomerulus, not reabsorbed from the nephron, and does not alter GFR.

    • This question is part of the following fields:

      • Physiology
      • Renal Physiology
      40.7
      Seconds
  • Question 22 - A 26-year-old male presents to your clinic with the complaint of recurrent fevers...

    Incorrect

    • A 26-year-old male presents to your clinic with the complaint of recurrent fevers over the past three months. On documentation of the fever, it is noted that the fever increases and decreases in a cyclical pattern over a 1-2 week period. After the appropriate investigations, a diagnosis of Pel-Ebstein fever is made.

      Which ONE of the following conditions is most likely to cause this patient's fever?

      Your Answer: Non-Hodgkin lymphoma

      Correct Answer: Hodgkin lymphoma

      Explanation:

      The release of cytokines from Reed-Sternberg cells can cause fever in patients with Hodgkin lymphoma, which increases and decreases in a cyclical pattern of 1 to 2 weeks. This is called Pel-Ebstein or Ebstein-Cardarelli fever, specifically seen in Hodgkin lymphoma. The fever is always high grade and can reach 40 degrees or higher.

      Cyclical fever in other conditions is common but is not termed as Pel-Ebstein fever. This term is reserved only with Hodgkin lymphoma.

    • This question is part of the following fields:

      • Haematology
      • Pathology
      40.8
      Seconds
  • Question 23 - You are reviewing a patient with hypocalcaemia secondary to hypoparathyroidism. Parathyroid hormone (PTH)...

    Incorrect

    • You are reviewing a patient with hypocalcaemia secondary to hypoparathyroidism. Parathyroid hormone (PTH) acts to increased calcium reabsorption at which of the following sites in the nephron:

      Your Answer: Ascending loop of Henle

      Correct Answer: Distal convoluted tubule

      Explanation:

      Parathyroid hormone (PTH) is a peptide hormone synthesised by the chief cells of the parathyroid glands, located immediately behind the thyroid gland. PTH is primarily released in response to decreasing plasma [Ca2+] concentration. PTH acts to increase plasma calcium levels and decrease plasma phosphate levels.
      Parathyroid hormone (PTH) acts to increase calcium reabsorption in the distal tubule of the nephron (by activating Ca2+entry channels in the apical membrane and the Ca2+ATPase pump in the basolateral membrane) and increase phosphate excretion by inhibiting reabsorption in the proximal tubule of the nephron.

    • This question is part of the following fields:

      • Endocrine
      • Physiology
      14
      Seconds
  • Question 24 - Regarding Gaussian sample distribution, which of the following statements is false? ...

    Incorrect

    • Regarding Gaussian sample distribution, which of the following statements is false?

      Your Answer: The mean is the arithmetic average

      Correct Answer: It can be skewed left or right

      Explanation:

      Gaussian distribution, also known as normal distribution, is the most important probability distribution in statistics because it fits many natural phenomena. The normal distribution is a probability function that describes how the values of a variable are distributed. Below are its characteristics:

      (1) Bell-shaped and symmetrical about the mean
      (2) The mean, median, mode are all equal
      (3) The total area under the curve and above the x-axis is equal to 1
      (4) It has long tapering tails extending infinitely but never touching the x-axis
      (5) It is determined by its parameters: its mean and standard deviation
      (6) The standard deviation becomes a more meaningful quality than merely being a measure of dispersion

      The mean is the most common measure of central tendency. It is the sum of all observed values divided by the number of observation, and is also known as the ‘average’.

      The median is the value that falls in the middle position when the observations are ranked in order from the smallest to the largest. If the number of observations is odd, the median is the middle number. If it is even, the median is the average of the two middle numbers.

      The mode is the value that occurs with the greatest frequency in a set of observations, and is commonly used in public health statistics, such as the top 10 causes of mortality.

    • This question is part of the following fields:

      • Evidence Based Medicine
      8.6
      Seconds
  • Question 25 - What is the primary route of transmission of Neisseria Gonorrhoeae? ...

    Correct

    • What is the primary route of transmission of Neisseria Gonorrhoeae?

      Your Answer: Sexually transmitted

      Explanation:

      Neisseria gonorrhoeae is primarily spread by sexual contact or through transmission during childbirth. It causes gonorrhoea which is a purulent infection of the mucous membrane surfaces.

    • This question is part of the following fields:

      • Microbiology
      • Pathogens
      4.2
      Seconds
  • Question 26 - Regarding the abductor digiti minimi, which of the following statements is false? ...

    Incorrect

    • Regarding the abductor digiti minimi, which of the following statements is false?

      Your Answer: It is innervated by the deep branch of the ulnar nerve

      Correct Answer: It assists with flexion of the fifth finger at the middle phalanx

      Explanation:

      Abductor digiti minimi is a short intrinsic muscle of the hand. It belongs to the group of muscles collectively called hypothenar muscles due to their acting on the 5th finger. Besides abductor digiti minimi, other hypothenar muscles include flexor digiti minimi brevis and opponens digiti minimi.

      The main function of abductor digiti minimi involves abduction of the 5th finger, as well as flexion of its proximal phalanx. Along with other hypothenar muscles, this muscle forms the hypothenar eminence on the medial side of the palm.

      Like other hypothenar muscles, abductor digiti minimi receives nervous supply from the deep branch of the ulnar nerve, derived from root values C8 and T1.

      Abductor digiti minimi receives arterial blood supply from the palmar branch of ulnar artery, palmar digital artery, as well as branches of the ulnar side of the superficial palmar arch. The venous blood from the muscle is drained via the venous networks of the palm into the deep veins of the arm (vv. ulnares).

    • This question is part of the following fields:

      • Anatomy
      • Upper Limb
      64.9
      Seconds
  • Question 27 - Which of the following statements is not true regarding ion channels? ...

    Correct

    • Which of the following statements is not true regarding ion channels?

      Your Answer: Ion channels provide a charged, hydrophobic pore through which ions can diffuse across the lipid bilayer.

      Explanation:

      Ion channels are pore-forming protein complexes that facilitate the flow of ions across the hydrophobic core of cell membranes. They are present in the plasma membrane and membranes of intracellular organelles of all cells, and perform essential physiological functions. They provide a charged, hydrophilic pore through which ions can move across the lipid bilayer. They are selective for particular ions and their pores may be opened or closed. Because of this ability to open and close, ion channels allow the cell to have the ability to closely control the movement of ions across the membrane. Gating refers to the transition between an open and closed ion channel state, and is brought about by a conformationational change in the protein subunits that open or close the ion-permeable pore.
      Ion channels can be:
      1. voltage-gated these are regulated according to the potential difference across the cell membrane or
      2. ligand-gated – these are regulated by the presence of a specific signal molecule.

    • This question is part of the following fields:

      • Basic Cellular
      • Physiology
      39.3
      Seconds
  • Question 28 - A 68-year-old patient shows Low calcium levels and is on dialysis for chronic...

    Incorrect

    • A 68-year-old patient shows Low calcium levels and is on dialysis for chronic kidney disease.

      What percentage of total serum calcium is in the form of free or ionised Ca 2+?

      Your Answer: 10%

      Correct Answer: 50%

      Explanation:

      Approximately half of total serum calcium is in the free or ionised Ca2+ state, 40% is attached to plasma proteins (mostly albumin), and the remaining 10% is in complexes with organic ions like citrate and phosphate. The ionized form is the only one that works.

    • This question is part of the following fields:

      • Endocrine Physiology
      • Physiology
      18.7
      Seconds
  • Question 29 - What is the interquartile range for these numbers: 11, 4, 6, 8, 3,...

    Correct

    • What is the interquartile range for these numbers: 11, 4, 6, 8, 3, 10, 8, 10, 4, 12, 31?

      Your Answer: 7

      Explanation:

      We obtain 3, 4, 4, 6, 8, 8, 10, 11, 12, and 31, and sample size (n) = 11 when we order the data. [(n+1)/2] = median 6th value = (11+1)/2 = [(n+1)/4] represents the bottom (first) quartile. (3rd value = 4th value = (11 + 1)/4 3[(n+1)/4] for the top (third) quartile 3[(11 + 1)/4] = 9th value = 11th value = 11th value = 11th value = 11th value = 11th value = 11th value = 11th value = 11th The difference between the upper and lower quartiles is the interquartile range, which is equal to 11 minus 4 = 7.

    • This question is part of the following fields:

      • Evidence Based Medicine
      • Statistics
      138.3
      Seconds
  • Question 30 - A patient has a cardiac output of 4.8 L/min and a heart rate...

    Correct

    • A patient has a cardiac output of 4.8 L/min and a heart rate of 80 bpm, therefore their stroke volume is:

      Your Answer: 60 mL

      Explanation:

      Cardiac output (CO) = Stroke volume (SV) x Heart rate (HR).
      Therefore SV = CO/HR
      = 4.8/80
      = 0.06 L = 60 mL.

    • This question is part of the following fields:

      • Cardiovascular
      • Physiology
      29.3
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Anaesthesia (0/1) 0%
Pharmacology (2/3) 67%
Cardiovascular Pharmacology (2/2) 100%
Anatomy (4/5) 80%
Lower Limb (1/1) 100%
Haematology (0/2) 0%
Pathology (2/6) 33%
Physiology (5/9) 56%
Renal Physiology (1/2) 50%
Evidence Based Medicine (2/4) 50%
Study Methodology (1/1) 100%
Thorax (2/2) 100%
Infections (0/1) 0%
Microbiology (1/3) 33%
Gastrointestinal (0/1) 0%
Respiratory Physiology (1/1) 100%
Inflammatory Responses (1/1) 100%
General Pathology (1/3) 33%
Endocrine (1/2) 50%
Pathogens (1/2) 50%
Abdomen And Pelvis (1/1) 100%
Upper Limb (0/1) 0%
Basic Cellular (1/1) 100%
Endocrine Physiology (0/1) 0%
Statistics (1/1) 100%
Cardiovascular (1/1) 100%
Passmed