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  • Question 1 - Which tumour site is more commonly involved in adults than in children? ...

    Correct

    • Which tumour site is more commonly involved in adults than in children?

      Your Answer: Lung

      Explanation:

      In adults, the most common primary site of tumour is in the lungs, compared to children wherein the most common primary site is the blood.

    • This question is part of the following fields:

      • Neoplasia
      • Pathology
      99.2
      Seconds

  • Question 2 - Which type of thyroid tumour represents 75 - 80% of thyroid cancer cases?...

    Correct

    • Which type of thyroid tumour represents 75 - 80% of thyroid cancer cases? This type is predominant in children and in patients who have had a previous history of head or neck radiation.

      Your Answer: Papillary carcinoma

      Explanation:

      Papillary thyroid carcinoma is the most common thyroid cancer. This cancer has a high cure rate with 10-year survival rates for all patients with papillary thyroid cancer estimated at 80% to 90%.

    • This question is part of the following fields:

      • Neoplasia
      • Pathology
      3.8
      Seconds

  • Question 3 - A 40-year-old woman is suspected to have an ovarian cancer. Which tumour marker...

    Correct

    • A 40-year-old woman is suspected to have an ovarian cancer. Which tumour marker should be requested to confirm the diagnosis?

      Your Answer: CA-125

      Explanation:

      CA-125 is a protein that is used as a tumour marker. This substance is found in high concentration in patients with ovarian cancer. It is the only tumour marker recommended for clinical use in the diagnosis and management of ovarian cancer.

    • This question is part of the following fields:

      • Neoplasia
      • Pathology
      5.1
      Seconds

  • Question 4 - A 4-year-old child was brought to a paediatrician for consult due to a...

    Correct

    • A 4-year-old child was brought to a paediatrician for consult due to a palpable mass in his abdomen. The child has poor appetite and regularly complains of abdominal pain. The child was worked up and diagnosed with a tumour. What is the most likely diagnosis ?

      Your Answer: Nephroblastoma

      Explanation:

      Nephroblastoma is also known as Wilms’ tumour. It is a cancer of the kidneys that typically occurs in children. The median age of diagnose is approximately 3.5 years. With the current treatment, approximately 80-90% of children with Wilms’ tumour survive.

    • This question is part of the following fields:

      • Neoplasia
      • Pathology
      9.9
      Seconds

  • Question 5 - An excised lesion is found to be a premalignant during examination by the...

    Correct

    • An excised lesion is found to be a premalignant during examination by the pathologist. What is the most likely histopathology report of this lesion?

      Your Answer: Solar keratosis

      Explanation:

      Premalignant condition is a state of disordered morphology of cells that is associated with an increased risk of cancer. If this condition is left untreated, it may lead to the development of cancer. The following are examples of pre-malignant lesions: actinic keratosis, Barret’s oesophagitis, atrophic gastritis, ductal carcinoma in situ, dyskeratosis congenita, sideropenic dysphagia, lichen planus, oral submucous fibrosis, solar elastosis, cervical dysplasia, leucoplakia and erythroplakia.

    • This question is part of the following fields:

      • Neoplasia
      • Pathology
      9.3
      Seconds

  • Question 6 - The patient who is diagnosed with bladder cancer asked his physician, what could...

    Correct

    • The patient who is diagnosed with bladder cancer asked his physician, what could have been the contributing factor in the development of his bladder cancer?

      Your Answer: Smoking

      Explanation:

      Tobacco smoking is the main known contributor to urinary bladder cancer. In most populations, smoking is associated with over half of bladder cancer cases in men and one-third of cases among women.

    • This question is part of the following fields:

      • Neoplasia
      • Pathology
      4.7
      Seconds

  • Question 7 - An electronic manufacturing engineer had abdominal distension and underwent a CT scan of...

    Correct

    • An electronic manufacturing engineer had abdominal distension and underwent a CT scan of the abdomen. Thereafter he was diagnosed with hepatic angiosarcoma. Exposure to what agent is responsible for the development of this neoplasm?

      Your Answer: Arsenic

      Explanation:

      Hepatic angiosarcomas are associated with particular carcinogens which includes: arsenic , thorotrast, and polyvinyl chloride. With exposure to this three agents, there is a very long latent period of many years between exposure and the development of tumours.

    • This question is part of the following fields:

      • Neoplasia
      • Pathology
      10
      Seconds

  • Question 8 - A patient is suspected to have a chromosomal abnormality. Which tumour and chromosomal...

    Correct

    • A patient is suspected to have a chromosomal abnormality. Which tumour and chromosomal association is correct?

      Your Answer: Neuroblastoma – chromosome 1

      Explanation:

      Neuroblastoma is associated with a deletion on chromosome 1 and inactivation of a suppressor gene. Neurofibromas and osteogenic sarcoma are associated with an abnormality on chromosome 17. Retinoblastoma (Rb) is associated with an abnormality on chromosome 13. Wilms’ tumours of the kidney are associated with an abnormality on chromosome 11.

    • This question is part of the following fields:

      • Neoplasia
      • Pathology
      21.8
      Seconds

  • Question 9 - A 72-year-old male presents with dysuria and chronic haematuria. He was diagnosed with...

    Incorrect

    • A 72-year-old male presents with dysuria and chronic haematuria. He was diagnosed with bladder cancer and tumour invasion of the perivesical fat. What is the stage of the patient's bladder cancer?

      Your Answer: T4

      Correct Answer: T3

      Explanation:

      Bladder cancer is the growth of abnormal or cancerous cells on the inner lining of the bladder wall. The staging is as follows; stage 0is (Tis, N0, M0): Cancerous cells in the inner lining tissue of the bladder only, stage I (T1, N0, M0): tumour has spread onto the bladder wall, stage II (T2, N0, M0): tumour has penetrated the inner wall and is present in muscle of the bladder wall, stage III (T3, N0, M0): tumour has spread through the bladder to fat around the bladder and stage IV: (T4, N0, M0): tumour has grown through the bladder wall and into the pelvic or abdominal wall. The stage of cancer in the case presented is T3 because of the invasion of perivesical fat.

    • This question is part of the following fields:

      • Neoplasia
      • Pathology
      26.9
      Seconds

  • Question 10 - A patient with Paget's disease of the bone is predisposed to developing which...

    Correct

    • A patient with Paget's disease of the bone is predisposed to developing which type of cancer?

      Your Answer: Osteosarcoma

      Explanation:

      Paget’s disease of bone (PDB) is a focal disorder of bone. It is presumed benign in nature and mediated by abnormal osteoclast function. However osteosarcomas may occur in <1% of patients with Paget's disease of the bone. Osteosarcomas are osteogenic in origin, and consistently arise in sites of pagetic bone. This is not to be confused with Paget's disease of the breast.

    • This question is part of the following fields:

      • Neoplasia
      • Pathology
      5.5
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Neoplasia (9/10) 90%
Pathology (9/10) 90%
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