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Question 1
Correct
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Efferent innervation of the muscle spindle is supplied by which type of motor neuron?
Your Answer: Gama – motor neuron
Explanation:The muscle spindle is supplied by both sensory and motor nerves. Sensory supply is via Type Ia fibers whereas the motor supply is via gamma motor neurons.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 2
Correct
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Dynein proteins transmit polypeptides/proteins in which direction?
Your Answer: From axons terminals to cell body (retrograde)
Explanation:The majority of axonal proteins are synthesised in the cell body and transported along the axons. Microtubules run along the length of the axon and provide tracks for transportation. Kinesin and Dynein are motor proteins that transport proteins and other organelles. Kinesin moves forward or anterograde transport from cell body to axon, whereas Dynein moves retrograde from axon to cell body.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 3
Incorrect
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The pathway responsible for the discriminative aspect of pain, is called the:
Your Answer: Spinothalamic tractus
Correct Answer: Neospinothalamic tract
Explanation:The spinothalamic tract is an ascending or a sensory tract, responsible for transmission of pain and temperature. The neospinothalamic tract is responsible for fast pain or discriminative pain whereas the palaeospinothalamic tract is responsible for transmission of slow pain.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 4
Correct
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Which enzyme is responsible for the removal of acetylcholine from the synapse?
Your Answer: Acetylcholinesterase
Explanation:Acetylcholinesterase is the enzyme that is responsible for breaking down acetylcholine into choline and acetate. Both of these molecules are transported back to the presynaptic neuron to be synthesized again. This enzyme is attached to the collagen fibers of the basement membrane in the synaptic cleft.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 5
Correct
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The following is true about the carotid arterial supply to the brain:
Your Answer: Following carotid occlusion, precapillary anastomoses are unable to prevent infarction
Explanation:The brain has two sources of blood supply; the internal carotid arteries which are the anterior segment or the main artery that supplies the anterior portion of the brain, and the vertebral arteries which is the posterior segment which supplies the posterior portion of the brain. The internal carotid arteries branch and form two major arteries anterior and middle cerebral arteries. The right and left vertebral arteries fuse together at the level of the pons on the anterior surface of the brainstem to form the midline basilar artery. The basilar artery joins the blood supply from the internal carotids in an arterial ring at the base of the brain called the circle of Willis. The anterior and posterior communicating arteries conjoin the two major sources of cerebral vascular supply via the circle of Willis improving the chances of any region of the brain continuing to receive blood if one of the major arteries becomes occluded.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 6
Correct
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Select the correct pairing regarding the surface of the cerebral hemispheres.
Your Answer: Parietal lobe : primary somatosensory cortex
Explanation:Right homonymous hemianopia is due to a lesion or pressure on the left optic tract.Total blindness of the left eye is due to a complete occlusion of the left optic nerve.Bipolar hemianopia is due to a midline chiasmal lesion.Left nasal hemianopia due to a lesion involving the left perichiasmal area.Right homonymous inferior quadrantanopia is due to involvement of the lower left optic radiations.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 7
Incorrect
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Which one of the following neurotransmitters is considered a monoamine?
Your Answer: Gaba
Correct Answer: Acetylcholine
Explanation:Acetylcholine is a major neurotransmitter in the peripheral nervous system. Monoamine neurotransmitters contain only one amino group joined to an aromatic ring. Acetylcholine is produced from acetyl-CoA and choline.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 8
Correct
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Which neurotransmitter is made from hydroxylation and decarboxylation of tryptophan?
Your Answer: Serotonin
Explanation:Serotonin is synthesized from the essential amino acid tryptophan. The rate-limiting step is the conversion of the amino acid to 5-hydroxytryptophan by tryptophan hydroxylase. This is then converted to serotonin by the aromatic L-amino acid decarboxylase.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 9
Correct
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On which presynaptic receptor does noradrenalin act to inhibit noradrenalin secretion?
Your Answer: Α2 receptor
Explanation:Adregenic receptors are A1, A2, B1, B2, B3. Out of these, the function of the A2 receptor is inhibition of transmitter release including nor adrenalin and acetylcholine of the autonomic nervous system.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 10
Correct
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Transportation of proteins from the cell body to axonal terminals is known as:
Your Answer: Axoplasmic flow
Explanation:Transportation of proteins from the cell body to axonal terminals is known as axoplasmic, axonal flow or Axonal transport.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 11
Correct
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The hippocampus is involved in the memory of:
Your Answer: Facts
Explanation:The hippocampus plays an important role in forming new memories about experienced events. Some researchers say that hippocampus plays a major role in declarative memory for example memory of facts.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 12
Correct
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Of the daily production of CSF, the vast majority is produced in the:
Your Answer: Choroid plexus
Explanation:About 80% of CSF is produced by the choroid plexus. It is also produced by a single layer of column shaped ependymal cells.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 13
Correct
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Which of the following is a form of synaptic plasticity?
Your Answer: Working memory
Explanation:Synaptic plasticity is an important neurochemical foundation of working memory and generation of memory. Synaptic plasticity is the ability of synapses to strengthen or weaken over time in response to increases or decreases in their activity.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 14
Correct
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Functions of the glossopharyngeal nerve include the following except:
Your Answer: Proprioceptive input from muscles of the tongue and larynx
Explanation:The glossopharyngeal nerve is a mixed nerve consisting of both sensory and motor fibers. It has several branches and five distinct general functions:Branchial motor- Special visceral efferent- supplies the Stylopharyngeus muscle and superior constrictor muscle.Visceral motor- general visceral efferent- provides parasympathetic innervation of the parotid gland.Visceral sensory- general visceral afferent- carries visceral sensory information from the carotid sinus and carotid body.General sensory- general somatic afferent- provides general sensory information from the inner surface of the tympanic membrane, upper pharynx and posterior one third of the tongue.Visceral afferent- special visceral afferent- provides taste sensation from the posterior one third of the tongue including the circumvallate papillae.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 15
Incorrect
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The nucleus tractus solitaries is medullary nucleus that processes the following inputs except:
Your Answer: Afferent impulses from the carotid baro- and chemoreceptors
Correct Answer: Sensory input from the semi-circular canal (CN VIII)
Explanation:Located in the brain stem is a series of purely sensory nuclei known as tractus solitaries. Inputs of the nucleus tractus solitaries include:Taste information from the facial nerve (anterior 2/3 of the tongue), glossopharyngeal nerve (posterior 1/3) and vagus nerve (small area on the epiglottis).Sensory information from the ear (auricular branch of the vagus nerve).Chemoreceptors and mechanoreceptors of the general visceral afferent pathway (GVA) in the carotid body via glossopharyngeal nerve, aortic bodies, and the sinoatrial node, via the vagus nerve.Chemically and mechanically sensitive neurons of the general visceral afferent pathway (GVA) with endings located in the heart, lungs, airways, gastrointestinal system, pharynx, and liver via the glossopharyngeal and vagus nerves.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 16
Correct
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The cavernous sinus is?
Your Answer: Lateral to the body of the sphenoid
Explanation:It is a venous sinus which creates a cavity called the lateral sellar compartment bordered by the temporal bone and the sphenoid bone. There are 2 on either side. It is about 1cm wide and extends from the posterior aspect of the orbit to the petrous part of the temporal bone. They sit on either side or lateral to the sphenoid bone.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 17
Incorrect
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Corticospinal tracts are located in the ___ of the white matter.
Your Answer: Posterior and lateral funiculi
Correct Answer: Anterior and lateral funiculi
Explanation:The corticospinal tract is a descending or a motor tract which projects nerve fibers from the cortex of the cerebrum down to different levels of the spinal cord. The descending corticospinal tract descends from the origin, through the corona radiata, posterior half of the lateral ventricle, and enters the midbrain through the cerebral peduncle. In the medulla they form the medullary pyramids on either side of midline as lateral and anterior fibers.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 18
Correct
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In which cell would you find a Nissl body?
Your Answer: Bipolar neuron
Explanation:Nissl bodies are the structures of protein synthesis in neurones. They are granular bodies of Rough Endoplasmic Reticulum and ribosomes. Astrocytes, Microglia, Schwann cell, oligodendrocytes are collectively known as glia or supporting cells of the nervous system.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 19
Correct
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Choose the correct answer: fibers in the superior cerebellar peduncle:
Your Answer: Are mainly ventral spinocerebellar tracts from the cerebellar nuclei to the thalamus and red nucleus
Explanation:There are three cerebellar peduncles with different connections and functions. The three are mainly, superior, middle and inferior. The superior cerebellar peduncle is also known as the “Brachium conjunctivum”. It predominantly contains efferent fibers from the cerebellar nuclei, as well as some afferents from the spinocerebellar tract. The efferent pathways include cerebellorubral, dentatothalamic, and fastigioreticular fibers. These are tracts projecting from the deep cerebellar nuclei to the thalamus and red nucleus. The middle cerebellar peduncle connects to the pontine nucleus and the dorsal spinocerebellar tracts run through the superior cerebellar peduncle.
The superior cerebellar peduncle contains vital afferent and efferent fibers including cerebellothalamic, cerebellorubral and ventrospinocerebellar tracts.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 20
Incorrect
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Which statement is incorrect regarding nociceptor C fibers…
Your Answer: Activity in the fiber activates a slow pain response
Correct Answer: They are thinly myelinated
Explanation:Group C nerve fibers are unmyelinated and have a small diameter, which means they conduct impulses at a low velocity. They carry sensory information and nociception.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 21
Correct
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The brainstem reticular formation, consists of which important control system responsible for consciousness and sleep?
Your Answer: RAS reticular activating system
Explanation:The reticular formation is a set of interconnected nuclei that are located along the brainstem. Reticular activating system (RAS) is a set of connected nuclei in the brain that is responsible for regulating wakefulness and sleep wake transitions and is the most influential component in the reticular formation.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 22
Correct
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The spinothalamic tracts are particularly concerned with…
Your Answer: Pain and temperature sensations
Explanation:The spinothalamic tracts are ascending or sensory tracts, responsible for transmission of pain and temperature.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 23
Correct
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The midbrain, medulla and pons, contain the following cranial nerve nuclei?
Your Answer: CN 3 - 12
Explanation:The cranial nerves (with the exception of I and II) originate in the brainstem, which includes the midbrain, the pons, and the medulla.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 24
Correct
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Question 25
Correct
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Which part of the cerebellum is primarily responsible for interacting with the motor cortex and planning and programming movements?
Your Answer: Cerebrocerebellum
Explanation:The cerebrocerebellum is the largest functional subdivision of the cerebellum, comprising of the lateral hemispheres and the dentate nuclei. It is involved in the planning and timing of movements, and in the cognitive functions of the cerebellum.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 26
Correct
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Into how many functional units can the cerebellum be divided?
Your Answer: 3
Explanation:The functional division of the cerebellum are the: Vestibulocerebellum (floculonodular lobe), Spinocerebellum (vermis and associated areas in the midline) and cerebrocerebellum (lateral hemispheres).
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This question is part of the following fields:
- Medicine
- Neurology
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Question 27
Correct
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Glucose transport in the brain is mediated by:
Your Answer: GLUT 1
Explanation:The facilitative glucose transporter mediates the transport of glucose from blood into neurons and glia in the brain. The primary isoforms in the brain are GLUT1 detected at high concentrations.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 28
Correct
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What is the most abundant cell type in the central nervous system called?
Your Answer: Astrocyte
Explanation:Astrocytes are the supporting cells of the central nervous system. There are two types; the fibrous type is found in the white matter and the protoplasmic type in the grey matter. They are the most abundant cell type in the CNS.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 29
Correct
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Endolymph in the inner ear is rich in:
Your Answer: K
Explanation:Cochlear fluids namely endolymph and perilymph have different compositions. Perilymph is a typical extracellular fluid, with ionic composition comparable to plasma or cerebrospinal fluid. The main cation is sodium. Endolymph is a totally unique extracellular fluid, with an ion composition unlike that which is found anywhere else in the body. The major cation in the endolymph is potassium and there is virtually no sodium.
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This question is part of the following fields:
- Medicine
- Neurology
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Question 30
Correct
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The ependyma fuse with which of the following to from the choroid plexus?
Your Answer: Tela choroidea
Explanation:The choroid plexus produces the cerebrospinal fluid (CSF) in the ventricles of the brain. It consists of modified ependymal cells. Tela choroidea is a region of pia mater of the meninges and underlying ependyma that’s a part of the choroid plexus. It is a very thin layer of the connective tissue of pia mater that overlies and covers the ependyma.
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This question is part of the following fields:
- Medicine
- Neurology
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