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  • Question 1 - Which of the following groups are purines? ...

    Correct

    • Which of the following groups are purines?

      Your Answer: Adenine, guanine, hypoxanthine

      Explanation:

      There are many naturally occurring purines. They include the nucleobases, adenine and guanine. Other notable purines are hypoxanthine, xanthine), theobromine, caffeine, uric acid and isoguanine.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      22.2
      Seconds

  • Question 2 - What catalyses the conversion of adenosine to inosine? ...

    Correct

    • What catalyses the conversion of adenosine to inosine?

      Your Answer: Adenosine deaminase

      Explanation:

      Adenosine deaminase (ADA) is an enzyme involved in purine metabolism. It is needed for the breakdown of adenosine from food and for the turnover of nucleic acids in tissues. ADA irreversibly deaminates adenosine, converting it to the related nucleoside inosine by the substitution of the amino group for a keto group.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      14.4
      Seconds

  • Question 3 - Which enzyme is deficient in the inborn error of metabolism called galactosemia? ...

    Correct

    • Which enzyme is deficient in the inborn error of metabolism called galactosemia?

      Your Answer: Galactose-1-phosphate uridyl transferase

      Explanation:

      Galactosaemia is a rare genetic autosomal recessive metabolic disorder. Lactose is broken down by the enzyme lactase into glucose and galactose. In individuals with galactosemia, the enzymes needed for further metabolism of galactose (Galactose-1-phosphate uridyltransferase) are severely diminished or missing entirely, leading to toxic levels of galactose 1-phosphate in various tissues.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      5.7
      Seconds

  • Question 4 - Lipid- lowering drugs like Lovastatin reduce cholesterol synthesis by inhibiting which enzyme? ...

    Correct

    • Lipid- lowering drugs like Lovastatin reduce cholesterol synthesis by inhibiting which enzyme?

      Your Answer: HMG-CoA reductase

      Explanation:

      Statins, also known as HMG-CoA reductase inhibitors, are a class of lipid-lowering medications. Statins have been found to reduce cardiovascular disease (CVD) and mortality in those who are at high risk.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      4.4
      Seconds

  • Question 5 - A deficiency in Niacin leads to which clinical deficiency syndrome? ...

    Correct

    • A deficiency in Niacin leads to which clinical deficiency syndrome?

      Your Answer: Pellagra

      Explanation:

      Pellagra is a disease caused by a lack of the vitamin niacin (vitamin B3). Symptoms include inflamed skin, diarrhoea, dementia, and sores in the mouth. Areas of the skin exposed to either sunlight or friction are typically affected first. Over time affected skin may become darker, stiff, begin to peel, or bleed.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      2.7
      Seconds

  • Question 6 - The main breakdown of fatty acids (by B-oxidation) occurs in which part of...

    Correct

    • The main breakdown of fatty acids (by B-oxidation) occurs in which part of the cell?

      Your Answer: Mitochondria

      Explanation:

      Once inside the mitochondria, the β-oxidation of fatty acids occurs via five recurring steps:Activation by ATPOxidation by FAD,Hydration,Oxidation by NAD+,Thiolysis,The final product is acetyl-CoA, the entry molecule for the citric acid cycle.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      7.7
      Seconds

  • Question 7 - In the urea cycle, which substance is formed in the mitochondria? ...

    Correct

    • In the urea cycle, which substance is formed in the mitochondria?

      Your Answer: Carbamoyl phosphate

      Explanation:

      Before the urea cycle begins ammonia is converted to carbamoyl phosphate in the mitochondria.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      9.4
      Seconds

  • Question 8 - Phosphorylation of glucose once it enters the cell is catalysed by which enzyme?...

    Correct

    • Phosphorylation of glucose once it enters the cell is catalysed by which enzyme?

      Your Answer: Hexokinase

      Explanation:

      Glucose 6-phosphate is produced by phosphorylation of glucose on the sixth carbon. This is catalysed by the enzyme hexokinase in most cells. One molecule of ATP is consumed in this reaction.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      8.3
      Seconds

  • Question 9 - A deficiency in Cyanocobalamin leads to which clinical deficiency syndrome? ...

    Correct

    • A deficiency in Cyanocobalamin leads to which clinical deficiency syndrome?

      Your Answer: Pernicious anaemia

      Explanation:

      The main syndrome of vitamin B12 deficiency is pernicious anaemia. It is characterized by a triad of symptoms:Megaloblastic anaemiaGastrointestinal symptoms &Neurological symptoms

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      4.8
      Seconds

  • Question 10 - Translation usually begins at which codon? ...

    Correct

    • Translation usually begins at which codon?

      Your Answer: AUG

      Explanation:

      The start codon is the first codon of a messenger RNA (mRNA) transcript translated by a ribosome. The start codon always codes for methionine in eukaryotes and the most common start codon is AUG.

    • This question is part of the following fields:

      • Medicine
      • Metabolism
      16.7
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Medicine (10/10) 100%
Metabolism (10/10) 100%
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