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  • Question 1 - Which of the following is likely to result in hematocolpos in a 12-year...

    Incorrect

    • Which of the following is likely to result in hematocolpos in a 12-year old girl?

      Your Answer: Turner syndrome

      Correct Answer: Imperforate hymen

      Explanation:

      Hematocolpos means accumulation of blood in vagina and hematometra is accumulation of blood in the uterus. These are most likely seen with an imperforate hymen; which is seen I 1 in 2000 females. If spontaneous resolution does not occur, treatment involves making a hole in the hymen to allow discharge of menstrual blood.

    • This question is part of the following fields:

      • Pathology
      • Women's Health
      14
      Seconds
  • Question 2 - Biopsy of a neoplastic mass was performed. Histologic examination of the specimen showed...

    Correct

    • Biopsy of a neoplastic mass was performed. Histologic examination of the specimen showed spindle shaped cells with high nuclear/cytoplasm ratio on immunohisto chemical staining. These pleomorphic cells were vimentin positive, cytokeratin negative and cd45 negative. This type of neoplasm is most commonly found in which patient?

      Your Answer: A 15-year-old boy with a mass in the left femur and lung metastases

      Explanation:

      A histology report that describes spindle shaped cells which are vimentin positive suggests osteosarcoma and hematogenous spread to the lungs.

    • This question is part of the following fields:

      • Neoplasia; Orthopaedics
      • Pathology
      50.2
      Seconds
  • Question 3 - Which of the following proteins prevents red blood cells (RBCs) from bursting when...

    Correct

    • Which of the following proteins prevents red blood cells (RBCs) from bursting when they pass through capillaries?

      Your Answer: Spectrin

      Explanation:

      Spectrin is a structural protein found in the cytoskeleton that lines the intercellular side of the membrane of cells which include RBCs. They maintain the integrity and structure of the cell. It is arranged into a hexagonal arrangement formed from tetramers of spectrin and associated with short actin filaments that form junctions allowing the RBC to distort its shape.

    • This question is part of the following fields:

      • General
      • Physiology
      13.1
      Seconds
  • Question 4 - A 30-year-old woman known with Von Willebrand disease (vWD) has to undergo surgery....

    Correct

    • A 30-year-old woman known with Von Willebrand disease (vWD) has to undergo surgery. Which of these complications is most unlikely in this patient?

      Your Answer: Hemarthrosis

      Explanation:

      Von Willebrand disease (vWD) is an inherited haemorrhagic disorder characterised by the impairment of primary haemostasis. It is caused by the deficiency or dysfunction of a protein named von Willebrand factor. The most common manifestation due to the condition is abnormal bleeding. Complications include easy bruising, hematomas, epistaxis, menorrhagia, prolonged bleeding and severe haemorrhage. Hemarthrosis is a complication that is more commonly found in haemophilia.

    • This question is part of the following fields:

      • Haematology
      • Pathology
      19
      Seconds
  • Question 5 - Ventricular filling follows a delay caused by? ...

    Correct

    • Ventricular filling follows a delay caused by?

      Your Answer: AV node

      Explanation:

      The AV node is a conducting tissue found between the atria and the ventricles of the heart. It conducts electrical signal from the atria to the ventricles and acts a delaying mechanism preventing the atria and the ventricles from contracting at the same time. This decremental conduction prevents premature ventricular contraction in cases such as atrial fibrillation. A delay in the AV node is the reason for the PR segment seen on the ECG. In certain types of supraventricular tachycardia, a person could have two AV nodes; this will cause a loop in electrical current and uncontrollably rapid heart beat. When this electricity catches up with itself, it will dissipate and return to a normal heart rate.

    • This question is part of the following fields:

      • Cardiovascular
      • Physiology
      23.1
      Seconds
  • Question 6 - An old man presented with atrophy of the thenar eminence despite the sensation...

    Correct

    • An old man presented with atrophy of the thenar eminence despite the sensation over it still being intact. What is the injured nerve in this case?

      Your Answer: Median nerve

      Explanation:

      Atrophy of the thenar muscles means injury to the motor supply of these muscles. The nerve that sends innervation to it is the median nerve. But the median nerve does not provide sensory innervation to the overlying skin so sensation is spared.

    • This question is part of the following fields:

      • Anatomy
      • Upper Limb
      8.5
      Seconds
  • Question 7 - A 50 year old woman presented with excessive bleeding after an inguinal hernia...

    Incorrect

    • A 50 year old woman presented with excessive bleeding after an inguinal hernia repair. Labs are suggestive of a primary haemostasis defect. Deficiency of which of the following is most likely to cause it?

      Your Answer: Protein C

      Correct Answer: Platelets

      Explanation:

      Primary haemostatic control means the first line of defence against immediate bleeding. This is carried out by the platelets. They immediately form a haemostatic plug at the site of injury. Coagulation starts within 20s after an injury to the blood vessel which damage the endothelial cells. Secondary haemostasis follows which includes activation of the coagulation factors to form fibrin strands which mesh together forming the platelet plug. Platelets interact with platelet collagen receptor, glycoprotein Ia/IIa and to collagen fibres in the vascular endothelium. This adhesion is mediated by von Willebrand factor (vWF), which forms links between the platelet glycoprotein Ib/IX/V and collagen fibrils. The platelets are then activated and release the contents of their granules into the plasma, in turn activating other platelets and white blood cells.

    • This question is part of the following fields:

      • General
      • Physiology
      18.7
      Seconds
  • Question 8 - Decreased velocity of impulse conduction through the atrioventricular node (AV node) in the...

    Incorrect

    • Decreased velocity of impulse conduction through the atrioventricular node (AV node) in the heart will lead to:

      Your Answer: Decreased PR interval

      Correct Answer: Increased PR interval

      Explanation:

      AV node damage may lead to an increase in the PR interval to as high as 0.25 – 0.40 s (normal = 0.12 – 0.20 s). In the case of severe impairment, there might be a complete failure of passage of impulses leading to complete block. In this case, the atria and ventricles will beat independently of each other.

    • This question is part of the following fields:

      • Cardiovascular
      • Physiology
      45
      Seconds
  • Question 9 - A 30 year old female suffered from mismatched transfusion induced haemolysis. Which substance...

    Correct

    • A 30 year old female suffered from mismatched transfusion induced haemolysis. Which substance will be raised in the plasma of this patient?

      Your Answer: Bilirubin

      Explanation:

      Bilirubin is a yellow pigment that is formed due to the break down of RBCs. Haemolysis results in haemoglobin that is broken down into a haem portion and globin which is converted into amino acids and used again. Haem is converted into unconjugated bilirubin in the macrophages and shunted to the liver. In the liver it is conjugated with glucuronic acid making it water soluble and thus excreted in the urine. Its normal levels are from 0.2-1 mg/dl. Increased bilirubin causes jaundice and yellowish discoloration of the skin.

    • This question is part of the following fields:

      • General
      • Physiology
      13.8
      Seconds
  • Question 10 - What percentage of cardiac output is delivered to the skin? ...

    Correct

    • What percentage of cardiac output is delivered to the skin?

      Your Answer: 2%

      Explanation:

      Making up 4-5% of total body weight, the skin receives approximately 2% of cardiac output.

    • This question is part of the following fields:

      • Cardiovascular
      • Physiology
      6.4
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Pathology (2/3) 67%
Women's Health (0/1) 0%
Neoplasia; Orthopaedics (1/1) 100%
General (2/3) 67%
Physiology (4/6) 67%
Haematology (1/1) 100%
Cardiovascular (2/3) 67%
Anatomy (1/1) 100%
Upper Limb (1/1) 100%
Passmed