FCP2-675
A 52-year-old woman who is a known case of breast cancer is being reviewed six months after she had a mastectomy following the diagnosis.
Which of the following tumour markers is the most useful in monitoring her disease?
FCP2 Category: Haematology & Oncology
FCP2-692
A 65-year-old man known to have renal cell carcinoma, is currently undergoing treatment. He presents to the acute medical ward with one month history of worsening central lower back pain, which becomes worse at night and cannot be managed with an analgesia at home. He has no other new symptoms.
Out of the following, which investigation should be performed next?
FCP2-676
A 53-year-old woman presents with a painless lump in the left breast associated with nipple discharge. The skin over the lump has an orange peel skin appearance. According to the patient, the lump has increased in size, with time.
Diagnosis of breast cancer is strongly suspected. Which of the following would be most useful in monitoring the prognosis of breast cancer, in this case?
FCP2-693
A 66-year-old baker presents to the oncology clinic with six-month history of weight loss and anorexia. Tumour marker profile shows an elevated level of bombesin.
Out of the following, which is the most likely cancer to account for this result?
FCP2-677
A 54-year-old woman presents to the A&E department with a five-day history of back pain which is located in the lower thoracic region and is worsened by coughing and sneezing. There has been no change in bowel habit or urinary symptoms. Her past medical history includes breast cancer and osteoarthritis. On examination, there is diffuse tenderness in the lower thoracic region. Perianal sensation is normal and lower limb reflexes are brisk.
Which one of the following is the most appropriate management plan?
FCP2-678
A 55-year-old female, on warfarin for mitral valve replacement and atrial fibrillation (AF), is due for extensive abdominal surgery.
What is the most appropriate step in regards to her anticoagulation therapy?
FCP2-680
A 58-year-old female patient is being investigated for breathlessness, cough, and severe weight loss. On the medical ward round, her CXR is reviewed showing hilar lymphadenopathy and multiple peripheral lung metastases.
Which of the following tumours is least likely to be the underlying cause of this lung appearance?
FCP2-664
A 46-year-old nurse presents with a short history of epistaxis and bleeding gums. Her complete blood count, coagulation profile, and blood film are requested. The results are as follows:
Hb: 8.6 g/dL
WCC: 2.3 x 10^9/L
Plts: 18 x 10^9/L
Coagulation profile: deranged
Blood film: bilobed large mononuclear cells
What is the most likely diagnosis?
FCP2-665
A 48-year-old man is diagnosed with acute myeloid leukaemia. Cytogenetic testing is carried out.
Which one of the following is mostly associated with a poor prognosis?
FCP2-666
A 48-year-old man is diagnosed with diffuse large B-cell lymphoma and is started on chemotherapy. Two days following his first treatment session, he presents to the A&E with nausea, vomiting, and myalgia. On examination, he appears clinically dehydrated. A diagnosis of tumour lysis syndrome (TLS) is suspected.
Which of the following would be consistent with the diagnosis of TLS?