FCP2-704

According to the Ann Arbor staging system for Hodgkin lymphoma, which one of the following would be staged as IIIB?

FCP2-705

An 82-year-old man is reviewed in the haematology clinic. He has been referred due to weight loss, lethargy, and a significantly elevated IgM level.

His recent blood results show:
Hb: 13.8 g/dL
Plts: 127 x 10^9/L
ESR: 45 mm/hr
IgM: 2150 mg/dL (50-330 mg/dL)

Given the probable diagnosis, which one of the following complications is he most likely to develop?

FCP2-706

An 86-year-old male patient has been diagnosed with monoclonal gammopathy of undetermined significance. He is eager to know its relation to his future health.

Which of the following statements is correct?

FCP2-707

In chemotherapy, what is the rationale behind using combinations of chemotherapeutic agents rather than single agents?

FCP2-708

Out of the following, which condition is not associated with hyposplenism?

FCP2-709

Out of the following, which is not associated with polycythaemia vera?

FCP2-710

Out of the following, which malignant tumour has the highest predilection for dissemination to the bones?

FCP2-711

Out of the following, which tumour cells are found in patients with Hodgkin disease?

FCP2-712

What are the most common types of transformation seen in patients with polycythaemia vera?

FCP2-701

A 8-year-old boy who recently migrated from Nigeria was seen in A&E department with a six-week history of progressive swelling of his jaw, fever, night sweats, and weight loss. His mother reported an episode of sore throat in the past which was treated with antibiotics, but he developed a rash subsequently. Other than that, there was no other significant past medical history. On examination, a painless, nontender 4x3cm mass was found that was fixed and hard. The only other examination finding of note was rubbery symmetrical cervical lymphadenopathy.

Which of the following translocation would most likely be found on biopsy karyotyping?