A 32-year-old male who is a known case of sickle cell disease presents to the Accident and Emergency (A&E) department with fever, tachypnoea, and rib pain. On examination, he has a low-grade fever of 37.9°C, oxygen saturation of 95% on air, and bilateral vesicular breath sounds on chest auscultation. CXR shows opacification in the right middle zone.
Which of these statements most accurately describes the initial management of this patient?
An 18-year-old boy with a history of bloody diarrhoea and fever, presents with a skin rash and low urine output. Blood tests and urinalysis reveal increased levels of urea and creatinine and haematuria. What is the most probable diagnosis?
Regarding haemochromatosis, which of the following is true?
A 23-year-old man is being investigated for excessive bleeding following a tooth extraction.
His coagulation profile shows:
Plts: 173 x 10^9/L
PT: 12.9 secs
APTT: 84 secs
Which clotting factor is he most likely deficient in?
A 23-year-old woman presents with lethargy. Her bloods show:
Hb: 10.4 g/dL
Plts: 278 x 10^9/L
WCC: 6.3 x 10^9/L
MCV: 68 fL
Blood film: Microcytic hypochromic RBCs, marked anisocytosis and basophilic stippling noted
HbA2: 3.9%
What is the most likely diagnosis?
A 6-year-old boy has been taken to his local hospital for his third sore throat in one month. Doctors have discovered bleeding from his gums and nose. He is also presenting with pale conjunctiva. From the list of options, what is the single cell type most likely to be seen on microscopy?
A 41-year-old woman has been complaining of tiredness over the past few weeks. She has angular stomatitis but no koilonychia. What is the most probable cell type to be seen in her blood film?
A 42-year-old woman who has been a smoker since she was a teenager has the following blood result: Hgb=19. What hormone should you check?
A 44-year-old lady was admitted with complaints of diarrhoea, loss of weight, moderate fever and generalized pallor. Her complete blood profile showed a decreased Hb with a raised MCV. The most likely diagnosis would be?
A 5-year-old child was found to have orchidomegaly and splenomegaly. Blood tests show a WBC = 1.7 X 104/L, Hb = 7.1 g/dl and platelets = 44 X 104g/dl. His parents mention that he suffers from fatigue while at presentation he looks pale and has a fever. What is the most likely diagnosis?