FCP2-655
A 4-year-old girl is diagnosed with acute lymphoblastic leukaemia after presenting with lethargy and easy bruising. Which of the following is a marker of a bad prognosis in this disease?
FCP2 Category: Haematology & Oncology
FCP2-656
A 40-year-old female is receiving a course of chemotherapy for breast cancer. She is, however, experiencing troublesome vomiting which is not responding to domperidone.
Which of the following is the most appropriate next step of management?
FCP2-657
A 40-year-old man has had multiple blood transfusions for sideroblastic anaemia. However, this time, 15 minutes into the blood transfusion, he complains of severe breathlessness. CXR shows diffuse bilateral pulmonary infiltrates.
What is the most likely diagnosis?
FCP2-658
A 42-year-old male patient is admitted with recurrent pancreatitis. He also has a history of parotitis. CT scan is carried out revealing no pancreatic mass, but evidence of widespread lymphadenopathy is seen. Dedicated liver imaging reveals a stricture in the common bile duct but no stones.
What is the most likely diagnosis?
FCP2-644
A 32-year-old woman was diagnosed with Hodgkin disease 8 years ago. She was treated with radiotherapy which led to complete remission.
What is the most likely long-term risk of radiotherapy?
FCP2-645
A 32-year-old woman, with a history of infertility, presented with postoperative bleeding from her abdominal wound. Her full blood count (FBC) and blood film showed hyperleukocytosis and the presence of promyelocytes, along with the following:
Hb: 9.2g/dL
Plts: 932 x 10^9/L
INR: 1.4 (Coagulation profile)
What should be the next step of management?
FCP2-646
A 33-year-old male presents with a rash and low grade fever (37.6°C). Twenty-one days ago, he underwent allogeneic bone marrow transplant for high-risk acute myeloid leukaemia. The rash was initially maculopapular affecting his palms and soles but 24 hours later, general erythroderma is noted involving the trunk and limbs. Other than that, he remains asymptomatic. His total bilirubin was previously normal but is now noted to be 40 μmol/L (1-22).
How would you manage the patient at this stage?
FCP2-647
A 33-year-old man presents with recurrent episodes of abdominal pain associated with weakness of his arms and legs.
Which one of the following urine tests would best indicate lead toxicity?
FCP2-632
A 24-year-old smoker with testicular cancer presents with exertional dyspnoea, wheezing, and persistent non-productive cough. He completed a course of chemotherapy comprising of cisplatin, bleomycin, and etoposide three months ago. On examination, there are fine bilateral basal crackles.
Which of the following is the most likely diagnosis?
FCP2-633
A 25-year-old female patient presents with massive haemorrhage. After grouping, her blood sample comes out to be B RhD negative.
You work in the hospital’s blood bank and are asked to prepare two units each of red blood cells (RBCs) and fresh frozen plasma (FFP). You manage to obtain the RBCs but not the Group B FFP as it is unavailable. Therefore, out of the following, FFP from a donor of which blood group would be best to transfuse?