-
Question 1
Correct
-
Afferent A δ fibers from nociceptors terminate primarily on neurons in which lamina:
Your Answer: I and V
Explanation:Nociceptors are receptors of pain sensation. There are 2 primary afferent/sensory pain fibers which transmit impulses from the receptor to the CNS, specifically to the dorsal horn of the spinal cord. The two fibers are A δ and C fibers. The dorsal horn of the spinal cord is the relay centre for sensory information converging from the periphery. Grey matter of the dorsal horn is subdivided in to laminae based on cytoarchitecture. C fibers terminate in lamina II the substantia gelatinosa. A δ fibers terminate primarily in lamina I but some project more deeply to terminate in lamina V.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 2
Correct
-
Question 3
Correct
-
The majority striatal neurons, called medium spiny neurons, utilizes which neurotransmitter?
Your Answer: GABA
Explanation:Medium spiny neurons are inhibitory neurons which use GABA (gamma-aminobutyric acid) which exerts inhibitory actions. These cells represent 95% of neurones within the human striatum found in basal ganglia.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 4
Incorrect
-
The pathway responsible for the discriminative aspect of pain, is called the:
Your Answer: Palaeospinothalamic tract
Correct Answer: Neospinothalamic tract
Explanation:The spinothalamic tract is an ascending or a sensory tract, responsible for transmission of pain and temperature. The neospinothalamic tract is responsible for fast pain or discriminative pain whereas the palaeospinothalamic tract is responsible for transmission of slow pain.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 5
Correct
-
What happens first during depolarisation of the membrane potential?
Your Answer: Gated Na channels open allowing the influx of Na
Explanation:Generation of an action potential in response to a stimulus is a result of a previously maintained resting membrane potential (RMP). Generation of resting membrane potential is mediated mainly by potassium ions. Several membrane proteins maintain RMP by transport of ions in and out of cell. Na+/K+ ATPase pump maintains a concentration gradient of Na+ and K+ ions. Na+ concentration in extracellular fluid is higher compared to intracellular fluid and K+ ion concentration is higher intracellularly. Generation of an action potential facilitates opening of Na+ ion channels which allow for Na+ to diffuse inside the cell according to the concentration gradient.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 6
Correct
-
Question 7
Correct
-
Question 8
Incorrect
-
Neurogenesis occurs throughout life in the following two areas:
Your Answer: Olfactory bulb and hippocampus
Correct Answer: Hippocampus and striatum
Explanation:In humans, neurogenesis or new neurons are continually born during adulthood in two regions of the brain: The subgranular zone (SGZ), part of the dentate gyrus of the hippocampus and the striatum. In other species of mammals, adult-born neurons also appear in the olfactory bulb. In humans, however, few if any olfactory bulb neurons are generated after birth.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 9
Correct
-
Which of the following do not pass through the cavernous sinus?
Your Answer: CN 2
Explanation:Oculomotor nerve (N3), trochlear nerve (N4), ophthalmic and mandibular divisions of the trigeminal nerve (N5) pass along its lateral border. The abducent nerve (N6) passes through it along with the internal carotid artery.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 10
Incorrect
-
The consensual light reflex is co-ordinated mainly in the:
Your Answer: Pretectal nucleus
Correct Answer: Edinger-Westphal nucleus
Explanation:The consensual light reflex occurs when an individual’s right eye is shielded and light shines into the left eye, constriction of the right pupil will occur, as well as the left. This is because the afferent signal sent through one optic nerve connects to the Edinger-Westphal nucleus, whose axons run to both the right and the left oculomotor nerves.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 11
Correct
-
Which cranial nerve is responsible for the parasympathetic nerve supply of the thorax and upper abdomen?
Your Answer: CN X
Explanation:Cranial nerve X supplies the structures of the thorax and abdomen. All the rest of the cranial nerves supply the structures in the head and neck
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 12
Correct
-
Which part of the cerebellum is primarily responsible for equilibrium and eye movements?
Your Answer: Vestibulocerebellum
Explanation:The vestibulocerebellum develops at the same time as the vestibular apparatus in the inner ear. Its regulates balance between agonist and antagonist muscle contractions of the spine, hips, and shoulders during rapid movements.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 13
Incorrect
-
The brainstem contains which of the following structures?
Your Answer: The subthalamus, midbrain and pons
Correct Answer: The midbrain, pons and medulla
Explanation:Brain stem is the base of the brain that connects the brain to the spinal cord. It consists of the mid brain, pons and medulla oblongata.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 14
Correct
-
Where do the spinothalamic axons decussate?
Your Answer: Spinal cord
Explanation:The second order neurons from the spinothalamic tract cross obliquely to the opposite side in the anterior grey and white commissure within one segment of the spinal cord.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 15
Correct
-
Regarding the innervation of cerebral blood vessels, which of the following triggers a vasoconstrictor effect?
Your Answer: Neuropeptide-Y
Explanation:Substance P is a potent vasodilator, VIP or vasoactive intestinal peptide has vasodilator properties in the intestines. PHM 27 is a potent calcitonin receptor agonist; endogenous analogue of human VIP. CGRP or Calcitonin Gene-Related Peptide is a vasodilator which is found to play an important role in migraines. Neuropeptide Y is a strong vasoconstrictor.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 16
Incorrect
-
Which neurotransmitter is found in the postganglionic parasympathetic synaptic cleft?
Your Answer: Noradrenalin
Correct Answer: Acetylcholine
Explanation:Acetylcholine is the neurotransmitter released from the postganglionic parasympathetic neuron into the synaptic cleft and also by some postganglionic sympathetic neurons as well.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 17
Incorrect
-
Myelin sheath in the CNS is produced by?
Your Answer:
Correct Answer: Oligodendrocytes
Explanation:CNS myelin is produced by special cells called oligodendrocytes. PNS myelin is produced by Schwann cells. The two types of myelin are chemically different, but they both perform the same function — to promote efficient transmission of a nerve impulse along the axon.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 18
Incorrect
-
Select the correct pairing regarding the surface of the cerebral hemispheres.
Your Answer:
Correct Answer: Parietal lobe : primary somatosensory cortex
Explanation:Parietal lobe: The primary somatosensory cortex is located in the postcentral gyrus of the parietal lobe. It is responsible for processing sensory information from the body.
Frontal lobe: The primary motor cortex is located in the precentral gyrus of the frontal lobe. The frontal lobe also contains the premotor cortex, which is involved in planning movements. The primary visual cortex is located in the occipital lobe, not the frontal lobe.
Temporal lobe: The primary auditory cortex is located in the superior temporal gyrus of the temporal lobe. The primary motor and premotor cortices are located in the frontal lobe, not the temporal lobe.
Occipital lobe: The primary visual cortex is located in the occipital lobe. The primary auditory cortex is located in the temporal lobe, not the occipital lobe.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 19
Incorrect
-
What is the most abundant cell type in the central nervous system called?
Your Answer:
Correct Answer: Astrocyte
Explanation:Astrocytes are the supporting cells of the central nervous system. There are two types; the fibrous type is found in the white matter and the protoplasmic type in the grey matter. They are the most abundant cell type in the CNS.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 20
Incorrect
-
Glucose transport in the brain is mediated by:
Your Answer:
Correct Answer: GLUT 1
Explanation:The facilitative glucose transporter mediates the transport of glucose from blood into neurons and glia in the brain. The primary isoforms in the brain are GLUT1 detected at high concentrations.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 21
Incorrect
-
Visual pathways - Choose the true statement:
Your Answer:
Correct Answer: The lateral geniculate nucleus, magnocellular & parvocellular pathways project to the primary visual cortex
Explanation:The optic chiasm is made by the decussation of optic fibers on the nasal side. The magnocellular pathway carries signals for detection of movement. The parvocellular pathway carries cells for detection of shape, size, colour and clarity. The lateral geniculate nucleus (LGN) is the relay centre in the thalamus for he visual pathway. It has layers of magnocellular cells and parvocellular cells that are interleaved with layers of koniocellular cells. The LGN is the main central connection for the optic nerve to the occipital lobe, particularly the primary visual cortex.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 22
Incorrect
-
The ependyma fuse with which of the following to from the choroid plexus?
Your Answer:
Correct Answer: Tela choroidea
Explanation:The choroid plexus produces the cerebrospinal fluid (CSF) in the ventricles of the brain. It consists of modified ependymal cells. Tela choroidea is a region of pia mater of the meninges and underlying ependyma that’s a part of the choroid plexus. It is a very thin layer of the connective tissue of pia mater that overlies and covers the ependyma.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 23
Incorrect
-
The thalamus is a large collection of neuronal groups within the diencephalons which participates in:
Your Answer:
Correct Answer: Sensory, motor and limbic
Explanation:The thalamus has multiple functions. It is the relay station for every sensory system (except olfactory, regulates the sleep-wake cycle and consciousness and also relays motor information.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 24
Incorrect
-
Which of the following is a form of synaptic plasticity?
Your Answer:
Correct Answer: Working memory
Explanation:Synaptic plasticity is an important neurochemical foundation of working memory and generation of memory. Synaptic plasticity is the ability of synapses to strengthen or weaken over time in response to increases or decreases in their activity.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 25
Incorrect
-
Cold receptors are likely to be active at the following temperatures except?
Your Answer:
Correct Answer: 39 °C
Explanation:Cold and Menthol receptor 1 (CMR1) is a protein that in humans is encoded by TRPM8 gene. It is primarily responsible for the detection of temperatures ranging from 8-28 C. It is an ion channel which upon activation causes the influx of Na+ and Ca+ ions into the cell that leads to the depolarization and generation of an action potential.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 26
Incorrect
-
Habituation…
Your Answer:
Correct Answer: Is a simple form of learning in which a neutral stimulus is repeated many times
Explanation:It is a simple form of learning where an organism decreases or ceases it’s response to a certain stimuli after repeated presentation. The organisms learns to stop responding to a stimulus which is no longer biologically relevant.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 27
Incorrect
-
The nucleus tractus solitaries is medullary nucleus that processes the following inputs except:
Your Answer:
Correct Answer: Sensory input from the semi-circular canal (CN VIII)
Explanation:Located in the brain stem is a series of purely sensory nuclei known as tractus solitaries. Inputs of the nucleus tractus solitaries include:Taste information from the facial nerve (anterior 2/3 of the tongue), glossopharyngeal nerve (posterior 1/3) and vagus nerve (small area on the epiglottis).Sensory information from the ear (auricular branch of the vagus nerve).Chemoreceptors and mechanoreceptors of the general visceral afferent pathway (GVA) in the carotid body via glossopharyngeal nerve, aortic bodies, and the sinoatrial node, via the vagus nerve.Chemically and mechanically sensitive neurons of the general visceral afferent pathway (GVA) with endings located in the heart, lungs, airways, gastrointestinal system, pharynx, and liver via the glossopharyngeal and vagus nerves.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 28
Incorrect
-
Functions of the glossopharyngeal nerve include the following except:
Your Answer:
Correct Answer: Proprioceptive input from muscles of the tongue and larynx
Explanation:The glossopharyngeal nerve is a mixed nerve consisting of both sensory and motor fibers. It has several branches and five distinct general functions:Branchial motor- Special visceral efferent- supplies the Stylopharyngeus muscle and superior constrictor muscle.Visceral motor- general visceral efferent- provides parasympathetic innervation of the parotid gland.Visceral sensory- general visceral afferent- carries visceral sensory information from the carotid sinus and carotid body.General sensory- general somatic afferent- provides general sensory information from the inner surface of the tympanic membrane, upper pharynx and posterior one third of the tongue.Visceral afferent- special visceral afferent- provides taste sensation from the posterior one third of the tongue including the circumvallate papillae.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 29
Incorrect
-
The brainstem reticular formation, consists of which important control system responsible for consciousness and sleep?
Your Answer:
Correct Answer: RAS reticular activating system
Explanation:The reticular formation is a set of interconnected nuclei that are located along the brainstem. Reticular activating system (RAS) is a set of connected nuclei in the brain that is responsible for regulating wakefulness and sleep wake transitions and is the most influential component in the reticular formation.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 30
Incorrect
-
Where are the cell bodies of preganglionic neurons located?
Your Answer:
Correct Answer: Lateral column
Explanation:The cell bodies of the preganglionic neurons are located in the lateral grey column of the spinal cord and in the motor nuclei of the 3rd, 7th, 9th and 10th cranial nerves.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 31
Incorrect
-
The cavernous sinus is?
Your Answer:
Correct Answer: Lateral to the body of the sphenoid
Explanation:It is a venous sinus which creates a cavity called the lateral sellar compartment bordered by the temporal bone and the sphenoid bone. There are 2 on either side. It is about 1cm wide and extends from the posterior aspect of the orbit to the petrous part of the temporal bone. They sit on either side or lateral to the sphenoid bone.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 32
Incorrect
-
The primary auditory cortex is:
Your Answer:
Correct Answer: Brodmann area 41
Explanation:A Brodmann area in the brain is defined by cytoarchitecture, histology and organization of cells:Primary Sensory 3,1,2Primary Motor 4Premotor 6Primary Visual 17Primary Auditory 41Brocas 44
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 33
Incorrect
-
The spinal cord receive its blood supply from the following arteries except:
Your Answer:
Correct Answer: Lateral spinal artery
Explanation:The spinal cord (SC) is supplied by the single anterior spinal artery which supplies the anterior two thirds of the SC and paired posterior spinal arteries supplying the posterior one third. Anastomoses between the spinal arteries supply the lateral column. These arteries originate near the cervico-occipital junction and therefore have a smaller calibre and often discontinue. Thus, they require reinforcement by segmental/radicular arteries which are branches of the ascending cervical artery, deep cervical artery, intercostal arteries, lumbar arteries and lateral sacral arteries
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 34
Incorrect
-
Dynein proteins transmit polypeptides/proteins in which direction?
Your Answer:
Correct Answer: From axons terminals to cell body (retrograde)
Explanation:The majority of axonal proteins are synthesised in the cell body and transported along the axons. Microtubules run along the length of the axon and provide tracks for transportation. Kinesin and Dynein are motor proteins that transport proteins and other organelles. Kinesin moves forward or anterograde transport from cell body to axon, whereas Dynein moves retrograde from axon to cell body.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 35
Incorrect
-
Regarding the innervation of the cerebral blood vessels, postganglionic sympathetic neurons have their cell bodies in the:
Your Answer:
Correct Answer: Superior cervical ganglia
Explanation:The superior cervical ganglion (SCG) is a part of autonomic system which plays a major role in maintaining homeostasis of the body. This ganglion innervates structures in the head and neck and is the largest and the most superiorly located ganglion. The SCG provides sympathetic innervation to structures within the head, including the pineal gland, the blood vessels in the cranial muscles and the brain, the choroid plexus, the eyes, the lacrimal glands, the carotid body, the salivary glands, and the thyroid gland. The postganglionic axons of the SCG innervate the internal carotid artery and form the internal carotid plexus. The internal carotid plexus carries the postganglionic axons of the SCG to the eye, lacrimal gland, mucous membranes of the mouth, nose, and pharynx, and numerous blood-vessels in the head.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 36
Incorrect
-
What is found in the posterior cavity of the eye?
Your Answer:
Correct Answer: Vitreous humor
Explanation:The eye ball contains an anterior cavity and a posterior cavity. The anterior cavity once again is divided into the anterior chamber and posterior chamber. The anterior cavity is filled with aqueous humor whereas the posterior cavity contains vitreous humor.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 37
Incorrect
-
The nucleus ambiguus:
Your Answer:
Correct Answer: Regulates swallowing, phonation and parasympathetic supply to the heart via CN IX, X and XI
Explanation:Nucleus Ambiguus is a group of large motor neurons found deep in the medullary reticular formation. It contains cell bodies of nerves that are responsible for the innervation of muscles of speech and swallowing which are located in the soft palate, pharynx and larynx. Additionally, it contains cholinergic preganglionic parasympathetic neurons of the heart via CN X, IX and XI
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 38
Incorrect
-
An example of cholinergic autonomic neurons are:
Your Answer:
Correct Answer: Sympathetic postganglionic neurons that innervate sweat glands.
Explanation:All preganglionic neurons in both the sympathetic and parasympathetic nervous system secrete acetylcholine. The postganglionic neurotransmitter of the parasympathetic nervous system in all neurons is acetylcholine. Postganglionic fibers of the sympathetic nervous system mainly secrete Noradrenalin and Adrenalin but at sweat glands and erector pili muscles the postganglionic neurotransmitter is acetylcholine.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 39
Incorrect
-
Which neurotransmitter is made from hydroxylation and decarboxylation of tryptophan?
Your Answer:
Correct Answer: Serotonin
Explanation:Serotonin is synthesized from the essential amino acid tryptophan. The rate-limiting step is the conversion of the amino acid to 5-hydroxytryptophan by tryptophan hydroxylase. This is then converted to serotonin by the aromatic L-amino acid decarboxylase.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 40
Incorrect
-
What landmark divides the frontal and parietal lobes?
Your Answer:
Correct Answer: Central sulcus
Explanation:The central sulcus divides the frontal lobe from the parietal lobe. It contains the motor cells for the movement function of the body.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 41
Incorrect
-
Which of the following associations is false?
Your Answer:
Correct Answer: Mandibular nerve – foramen lacerum
Explanation:– The olfactory nerves pass through the cribriform plate- The maxillary division of the trigeminal nerve passes through the foramen rotundum- The facial nerve passes through the stylomastoid foramen- The mandibular division of the trigeminal nerve pass through the foramen ovale- The glossopharyngeal nerve passes through the jugular foramen.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 42
Incorrect
-
Which serotonergic receptor is associated with vomiting?
Your Answer:
Correct Answer: 5ht3
Explanation:5ht3 is a receptor strongly associated with vomiting, present in vagal afferents, the solitary tract nucleus (STN), and the area posterior. For this reason, 5ht3 antagonists are commonly used as antiemetic drugs. They include ondansetron, tropisetron, and granisetron.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 43
Incorrect
-
In Argyll Robertson pupils…
Your Answer:
Correct Answer: All of the options given
Explanation:Argyll Robertson pupils are bilaterally small pupils that accommodate or reduce in size near an object but do not react to light. They do not constrict when exposed to bright light. They are a highly specific sign of neurosyphilis but may be seen in diabetic neuropathy as well.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 44
Incorrect
-
Concerning the sleep-wake cycle, Melatonin is secreted by which structure in the brain following which environmental conditions?
Your Answer:
Correct Answer: Pineal gland, darkness
Explanation:Melatonin is secreted by the pineal gland located in the midline attached to the posterior roof of the third ventricle in the brain. Melatonin affects circadian rhythm in the body or the sleep wake cycle. The precursor to melatonin is serotonin and the rate limiting enzyme that converts serotonin to melatonin is low during the day time and reaches its peak during the night.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 45
Incorrect
-
In a 60kg adult male with normal mean arterial pressure and oxygen consumption, what proportion of the cardiac output at rest goes to the brain?
Your Answer:
Correct Answer: 10-15%
Explanation:The rate of cerebral blood flow in the adult is typically 750 millilitres per minute, which is 10-15% of the cardiac output. On average around 13.9% of cardiac output is distributed to the brain.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 46
Incorrect
-
Question 47
Incorrect
-
The axons of which neurons serve as the only output from the cerebellar cortex?
Your Answer:
Correct Answer: Purkinje
Explanation:The cerebellar cortex consist of 3 layers. The molecular layer, the granule cell layer and the Purkinje cell layer in the middle. The Purkinje cells project into the deep cerebellar nuclei. They are the only output cells of the cerebellar cortex.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 48
Incorrect
-
The Afferent neuron that supplies all sensory elements of the muscle spindle is what type of sensory neuron?
Your Answer:
Correct Answer: Ia
Explanation:Muscle spindle is supplied by both sensory and motor nerves. Sensory supply is Type Ia fibers whereas motor supply is gamma motor neurone.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 49
Incorrect
-
The pontine tegmentum as part of the midbrain, contains which cranial nerve nuclei?
Your Answer:
Correct Answer: CN 5 to 8
Explanation:The pontine tegmentum also known as dorsal pons is located within the brain stem. Several cranial nerve nuclei are located in the pontine tegmentum. The nuclei of CN V, CN VI, CN VII and CNVIII are located in the pontine tegmentum.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 50
Incorrect
-
The tectum as part of the Midbrain contains which structure important in visual reflexes.
Your Answer:
Correct Answer: Superior colliculus
Explanation:The tectum is a part of the midbrain, specifically, the dorsal part of the midbrain. The tectum consists of the superior and inferior colliculi. The superior colliculus is involved in preliminary visual processing and control of eye movement.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 51
Incorrect
-
Choose the correct answer: The interposed nuclei…
Your Answer:
Correct Answer: Are the emboliform and globose nuclei in the paravermis
Explanation:The interposed nuclei are a part of deep cerebellar complex and are composed of the globose nucleus and the emboliform nucleus. It receives afferent fibers from the anterior lobe of the cerebellum and sends output via the superior cerebellar peduncle to the red nucleus.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 52
Incorrect
-
Which of the following is the smallest cell of the nervous system?
Your Answer:
Correct Answer: Microglia
Explanation:Microglia are the smallest of the neuroglial cells in the nervous system. They are scattered throughout the central nervous system and have phagocytic properties.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 53
Incorrect
-
Which dorsal (sensory) root is responsible for umbilical area sensation?
Your Answer:
Correct Answer: T10
Explanation:The area of skin supplied by one nerve is called a dermatome. T10 supplies sensory neurons to the area of the umbilicus. C3 and C4 supply the neck and the shoulder, T4 supplies the dermatome at the level of the nipple, S3 supplies the inguinal region and L5 supplies the lateral aspect of the leg and the medical aspect of the dorsum of the feet plus the first 3 toes.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 54
Incorrect
-
Regarding the formation of CSF, which of the following is true?
Your Answer:
Correct Answer: Its composition resembles that of brain ECF
Explanation:In normal adults CSF volume is around 125ml to 150ml. Turnover of entire volume of cerebrospinal fluid a day is about 3 to 4 times a day. Composition of CSF is similar to that of plasma except that CSF is nearly protein-free compared with plasma and has a different electrolyte level. About 80% of CSF is produced by the choroid plexus. It is also produced by a single layer of column shaped ependymal cells. The composition and rate of CSF generation depends on several factors and is influenced by hormones and the content and pressure of blood and CSF.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 55
Incorrect
-
The superior orbital fissure is the site of entry/exit for which of the following group of nerves?
Your Answer:
Correct Answer: CN III, IV, V1, VI
Explanation:The superior and inferior divisions of oculomotor nerve (III), trochlear nerve (IV), lacrimal, frontal and nasociliary branches of ophthalmic V1 and the abducens nerve (VI)
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 56
Incorrect
-
Question 57
Incorrect
-
Which enzyme is responsible for the removal of acetylcholine from the synapse?
Your Answer:
Correct Answer: Acetylcholinesterase
Explanation:Acetylcholinesterase is the enzyme that is responsible for breaking down acetylcholine into choline and acetate. Both of these molecules are transported back to the presynaptic neuron to be synthesized again. This enzyme is attached to the collagen fibers of the basement membrane in the synaptic cleft.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 58
Incorrect
-
Regarding CSF:
Your Answer:
Correct Answer: Disruption of arachnoid villi function results in a communicating hydrocephalus
Explanation:In normal adults CSF volume is around 125ml to 150ml. Turnover of the entire volume of cerebrospinal fluid is about 3 to 4 times a day. Composition of CSF is similar to that of plasma except that CSF is nearly protein-free compared with plasma and has different electrolyte levels. Blockage of the foramina causes an obstructive or non-communicating hydrocephalus. Communicating hydrocephalus or non-obstructive hydrocephalus is caused by impaired CSF reabsorption in the absence of any CSF flow obstruction.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 59
Incorrect
-
Which receptor type is associated with uterine contracture in pregnancy?
Your Answer:
Correct Answer: Α1
Explanation:Alpha-1 adrenergic receptors cause uterine contraction during pregnancy. They are linked to Gq-proteins that activate smooth muscle contraction through the IP3 signal transduction pathway.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 60
Incorrect
-
The hippocampus is involved in the memory of:
Your Answer:
Correct Answer: Facts
Explanation:The hippocampus plays an important role in forming new memories about experienced events. Some researchers say that hippocampus plays a major role in declarative memory for example memory of facts.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 61
Incorrect
-
Which one of the following neurotransmitters is considered a monoamine?
Your Answer:
Correct Answer: Dopamine
Explanation:Monoamines are a class of neurotransmitters that include:
- Dopamine: A neurotransmitter involved in reward, motivation, and motor control.
- Norepinephrine: A neurotransmitter involved in arousal, attention, and stress responses.
- Serotonin: Although not listed in the options, it is another key monoamine involved in mood regulation.
The other neurotransmitters listed are not monoamines:
- Acetylcholine: This is a different type of neurotransmitter involved in muscle activation and various brain functions.
- GABA (gamma-aminobutyric acid): This is the main inhibitory neurotransmitter in the central nervous system.
- Glutamate: This is the main excitatory neurotransmitter in the central nervous system.
- Glycine: An inhibitory neurotransmitter in the central nervous system.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 62
Incorrect
-
During which stage of sleep is muscle tone in the limbs most reduced?
Your Answer:
Correct Answer: REM
Explanation:Rapid eye movement (REM) stage is marked by extensive physiological changes in the body, such as accelerated respiration, increased brain activity and muscle relaxation. People dream during REM sleep, perhaps as a result of excited brain activity and the paralysis of major voluntary muscles.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 63
Incorrect
-
Which receptor type is associated with bronchial muscle relaxation?
Your Answer:
Correct Answer: β2
Explanation:β2-adrenoceptors are widely distributed in the respiratory tract. When they are activated, an intracellular response induces the activation of cyclic AMP; this, in turn, produces airway relaxation through phosphorylation of muscle regulatory proteins and modification of cellular Ca2+concentrations.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 64
Incorrect
-
The motor speech area (Brocas Area) is:
Your Answer:
Correct Answer: Brodmann area 44
Explanation:A Brodmann area in the brain is defined by cytoarchitecture, histology and organization of cells:Primary Sensory 3,1,2Primary Motor 4Premotor 6Primary Visual 17Primary Auditory 41Brocas 44
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 65
Incorrect
-
Which substance has the lowest taste threshold concentration, in other words which substance can be present in the lowest concentration before taste buds will respond?
Your Answer:
Correct Answer: Strychnine hydrochloride (bitter)
Explanation:The lowest concentration of a gustatory stimulus to which the taste buds respond is considered to be the threshold concentration for that substance. The threshold concentration for strychnine is 0.0001 mm; this is because it allows the body to detect potentially dangerous substances (bitter plant components) at lower concentrations.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 66
Incorrect
-
Which afferent information is carried by the dorsal column?
Your Answer:
Correct Answer: Proprioception/ discriminative touch
Explanation:The posterior grey column (dorsal column) is responsible for carrying the sensation of proprioception, two-point discrimination, and vibration to the nucleus proprius, situated anterior to the substantia gelatinosa throughout the spinal cord.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 67
Incorrect
-
Of the daily production of CSF, the vast majority is produced in the:
Your Answer:
Correct Answer: Choroid plexus
Explanation:About 80% of CSF is produced by the choroid plexus. It is also produced by a single layer of column shaped ependymal cells.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 68
Incorrect
-
The primary sensory cortex is:
Your Answer:
Correct Answer: Brodmann area 3,1,2
Explanation:A Brodmann area in the brain is defined by cytoarchitecture, histology and organization of cells:Primary somatosensory cortex is areas 3,1, and 2Primary Motor 4Premotor 6Primary Visual 17Primary Auditory 41Brocas 44
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 69
Incorrect
-
Which of the following runs in the upper part of the falx cerebri?
Your Answer:
Correct Answer: Superior sagittal sinus
Explanation:Falx cerebri is a sickle cell fold of dura between the two hemispheres. Its posterior part blends with the superior part of the tentorium cerebelli. The superior sagittal sinus runs in its upper fixed margin, the inferior sagittal sinus in the free concave margin and the straight sinus along its attachment to the tentorium cerebelli.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 70
Incorrect
-
Which part of the cerebellum is primarily responsible for interacting with the motor cortex and planning and programming movements?
Your Answer:
Correct Answer: Cerebrocerebellum
Explanation:The cerebrocerebellum is the largest functional subdivision of the cerebellum, comprising of the lateral hemispheres and the dentate nuclei. It is involved in the planning and timing of movements, and in the cognitive functions of the cerebellum.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 71
Incorrect
-
In the basal ganglia, the Lentiform nucleus is formed by which two nuclei?
Your Answer:
Correct Answer: Putamen and Globus pallidus
Explanation:The Basal Ganglia are composed of the following structures: Caudate, putamen, Globus pallidus, subthalamic nucleus and substantia nigra.
The Lentiform nucleus is a biconvex structure located within the basal ganglia of the brain. It is composed of two nuclei:
- Putamen: This is the outer part of the Lentiform nucleus and is involved in regulating movements and various types of learning.
- Globus pallidus: This is the inner part of the Lentiform nucleus and is divided into two segments: the external segment (GPe) and the internal segment (GPi). It plays a key role in the regulation of voluntary movement.
These two structures together form the Lentiform nucleus, which is an integral part of the basal ganglia system involved in motor control.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 72
Incorrect
-
Which one of the following nerve fibers is involved in proprioception?
Your Answer:
Correct Answer: An α fiber
Explanation:Proprioception, also known as kinaesthesia, is the sense through which humans perceive their own position and movements. α nerve fibers are specifically involved in transmitting proprioception stimuli.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 73
Incorrect
-
Cranial nerves VI, VII, VIII enter/exit the base of the brain at the:
Your Answer:
Correct Answer: Ponto-medullary junction
Explanation:Cranial nerves III, IV and V exit from the pons, VI, VII, VIII exit from the pontomedullary junction and cranial nerve IX, X, XI, XII exit from the medulla.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 74
Incorrect
-
The main reason for the prolonged effect of the withdrawal reflex is:
Your Answer:
Correct Answer: Multiple connections between afferent and efferent neurons
Explanation:The withdrawal reflex is a spinal reflex that protects the body from harmful stimuli. Spinal reflexes are mostly monosynaptic and are mediated by a simple reflex arc. Withdrawal reflex is mediated by a polysynaptic reflex resulting in stimulation of many motor neurons in order to establish a quick and prolonged response.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 75
Incorrect
-
Visceral afferent fibers are found in the following areas except the…?
Your Answer:
Correct Answer: Trigeminal nerve
Explanation:The general visceral afferent (GVA) fibers carry impulses from viscera to the central nervous system. The cranial nerves that contain GVA fibers include the facial nerve, the glossopharyngeal nerve and the vagus nerve
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 76
Incorrect
-
Which part of the neuron has the highest concentration of sodium channels per square millimetre of the cell membrane?
Your Answer:
Correct Answer: Nodes of Ranvier
Explanation:The nodes of Ranvier contain Na+/K+ ATPases, Na+/Ca2+ exchangers and a high density of Na+ channels. The estimated concentration of sodium channels in the node is of ∼1500/μm2.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 77
Incorrect
-
Question 78
Incorrect
-
Interruption of the left optic tract will result in which visual field defect?
Your Answer:
Correct Answer: Right homonymous hemianopia
Explanation:Right homonymous hemianopia is due to a lesion or pressure on the left optic tract. Total blindness of the left eye is due to a complete occlusion of the left optic nerve. Bipolar hemianopia is due to a midline chiasmal lesion. Left nasal hemianopia due to a lesion involving the left perichiasmal area. Right homonymous inferior quadrantanopia is due to involvement of the lower left optic radiations.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 79
Incorrect
-
Where are the cell bodies to the preganglionic neurons located?
Your Answer:
Correct Answer: Midbrain
Explanation:The cell bodies of the preganglionic neurons are located in the lateral grey column of the spinal cord and in the motor nuclei of the 3rd, 7th, 9th and 10th cranial nerves. These cranial nerves take origin from the midbrain.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 80
Incorrect
-
The outer and inner surfaces of the arachnoid mater is covered with:
Your Answer:
Correct Answer: Mesothelial cells
Explanation:The arachnoid mater is one of the three meninges that covers the brain and spinal cord. It is interposed between the two other meninges, the more superficial and much thicker dura mater and the deeper pia mater, from which it is separated by the subarachnoid space. The arachnoid mater consists of a subdural mesothelial layer and a compact central layer
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 81
Incorrect
-
Choose the correct answer: The cerebrocerebellum…
Your Answer:
Correct Answer: All options are correct
Explanation:Cerebrocerebellum is comprised of two lateral regions, the cerebellar hemispheres and communicates with the cerebral cortex. It is principally responsible for controlling coordination of movement. Three fiber bundles carry the input and output of the cerebellum. There are three cerebellar peduncles with different connections and functions. The three are mainly, superior, middle and inferior. The superior cerebellar peduncle is also known as the “Brachium conjunctivum”. It predominantly contains efferent fibers from the cerebellar nuclei, as well as some afferents from the spinocerebellar tract. The efferent pathways include cerebellorubral, dentatothalamic, and fastigioreticular fibers. These are tracts projecting from the deep cerebellar nuclei to the thalamus and red nucleus. The middle cerebellar peduncle connects to the pontine nucleus and the dorsal spinocerebellar tracts run through the superior cerebellar peduncle
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 82
Incorrect
-
The majority of corticospinal tract fibers decussate in the:
Your Answer:
Correct Answer: Medulla
Explanation:The corticospinal tract is a descending motor path way that begins in the cerebral cortex and decussates in the pyramids of the medulla.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 83
Incorrect
-
Which one of the following nerve fibers has the fastest conduction velocity?
Your Answer:
Correct Answer: α fiber
Explanation:α nerve fibers are characterized by being highly myelinated, which confers them with fast conduction properties. They innervate extrafusal skeletal muscle fibers, and their conduction velocity is between 80-120 m/s.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 84
Incorrect
-
Which of the following tracts are involved in the control of vital functions?
Your Answer:
Correct Answer: Reticulospinal
Explanation:Reticulospinal tract pass down from the reticular formation of the mid brain, pons and medulla. It descends in the lateral white column. Both sets of fibers enter the anterior grey column and may facilitate or inhibit the gamma and alpha neurons. By this means the reticulospinal tract controls voluntary and reflex activities. It also contains the descending autonomic fiber, thus providing a pathway for the hypothalamus to control the sympathetic and parasympathetic pathways.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 85
Incorrect
-
Transportation of proteins from the cell body to axonal terminals is known as:
Your Answer:
Correct Answer: Axoplasmic flow
Explanation:Transportation of proteins from the cell body to axonal terminals is known as axoplasmic, axonal flow or Axonal transport.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 86
Incorrect
-
Question 87
Incorrect
-
Choose the correct answer: fibers in the superior cerebellar peduncle:
Your Answer:
Correct Answer: Are mainly ventral spinocerebellar tracts from the cerebellar nuclei to the thalamus and red nucleus
Explanation:There are three cerebellar peduncles with different connections and functions. The three are mainly, superior, middle and inferior. The superior cerebellar peduncle is also known as the “Brachium conjunctivum”. It predominantly contains efferent fibers from the cerebellar nuclei, as well as some afferents from the spinocerebellar tract. The efferent pathways include cerebellorubral, dentatothalamic, and fastigioreticular fibers. These are tracts projecting from the deep cerebellar nuclei to the thalamus and red nucleus. The middle cerebellar peduncle connects to the pontine nucleus and the dorsal spinocerebellar tracts run through the superior cerebellar peduncle.
The superior cerebellar peduncle contains vital afferent and efferent fibers including cerebellothalamic, cerebellorubral and ventrospinocerebellar tracts.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 88
Incorrect
-
The neurotransmitter utilised by the Purkinje cells is:
Your Answer:
Correct Answer: GABA
Explanation:The cerebellar cortex consist of 3 layers: the molecular layer, the granular cell layer and the Purkinje cell layer. Purkinje cells play a fundamental role in controlling motor movement. They release a neurotransmitter called GABA (gamma-aminobutyric acid) which exerts inhibitory actions thereby reducing transmission of impulses. These inhibitory functions enable purkinje cells to regulate and coordinate motor movements.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 89
Incorrect
-
Question 90
Incorrect
-
An exaggerated response to a noxious stimulus is called:
Your Answer:
Correct Answer: Hyperalgesia
Explanation:Allodynia is the sensation of pain following non-painful stimulation.
Hyperalgesia is enhanced intensity of pain sensation.
Causalgia is a constant burning pain resulting from peripheral nerve injury.
Hyperesthesia is the abnormal increase in sensitivity to stimuli of sense.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 91
Incorrect
-
Regarding taste threshold and intensity discrimination:
Your Answer:
Correct Answer: 30% change in concentration of substance tasted is necessary before an intensity difference can be detected
Explanation:The ability of humans to differentiate differences in intensity of taste is poor. A 30% change in the concentration of the substance being tasted is required before an intensity difference is perceived.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 92
Incorrect
-
Wernicke’s area:
Your Answer:
Correct Answer: Is concerned with comprehension of auditory and visual information
Explanation:Wernicke’s area is located in the categorical hemisphere or left hemisphere in about 95% of right handed individuals and 60% of left handed individuals. It is involved in the comprehension or understanding of written and spoken language. In contrast Broca’s area is involved in production of language.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 93
Incorrect
-
Which neurotransmitter is released from the postganglionic fibers in the sympathetic division?
Your Answer:
Correct Answer: Noradrenalin
Explanation:Noradrenalin Is the neurotransmitter that is released from the postganglionic fibers of the sympathetic division. It is stored in granules at the sympathetic knobs. It Is a methyl derivative.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 94
Incorrect
-
Endolymph in the inner ear is rich in:
Your Answer:
Correct Answer: K
Explanation:Cochlear fluids namely endolymph and perilymph have different compositions. Perilymph is a typical extracellular fluid, with ionic composition comparable to plasma or cerebrospinal fluid. The main cation is sodium. Endolymph is a totally unique extracellular fluid, with an ion composition unlike that which is found anywhere else in the body. The major cation in the endolymph is potassium and there is virtually no sodium.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 95
Incorrect
-
A lesion that interrupts one optic nerve causes blindness:
Your Answer:
Correct Answer: In the eye on the same side as the optic nerve
Explanation:The optic nerve on each side contains medial and lateral fibers originating from the retina. Medial fibers cross at the optic chiasm and become the optic tract ending in the visual cortex of the occipital lobe. If there is a lesion interrupting the “optic nerve” on one side, the same side eye will be completely blind.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 96
Incorrect
-
Which ventral (motor) root is responsible for triceps?
Your Answer:
Correct Answer: C7
Explanation:Of the nerve fibers that make up the brachial plexus, C7 mainly forms the radial nerve to innervate the triceps muscle, thus innervating the shoulders, elbow, wrist and hand. C7 is responsible for the triceps reflex.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 97
Incorrect
-
Question 98
Incorrect
-
Which one of the following cells originates from a monocyte and resembles a macrophage?
Your Answer:
Correct Answer: Microglia
Explanation:Microglia act as the macrophages of the central nervous system, and they contribute to innate and adaptive immune responses. Studies have shown that microglial cells recognize monocyte antigens, and there are similarities between them that demonstrate that they originate from these monocytes.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 99
Incorrect
-
Salty taste is triggered by:
Your Answer:
Correct Answer: Amiloride-sensitive sodium channel
Explanation:Amiloride-sensitive sodium channels also known as epithelial Na channels is a membrane bound ion channel that is selectively permeable to Na+ ions. These channels are located throughout different epithelial membranes in the body. It is found in taste receptor cells, where it plays an important role in salt taste perception. They are also located in the kidney, the lung and the colon. Hyperpolarization-activated, cyclic nucleotide-gated (HCN) voltage-gated ion channels are widely seen in the cortex, hippocampus, thalamus and brain regions that underlie the generation of both focal and generalized-onset seizures. The metabotropic glutamate receptor (mGluRs) perform a variety of functions in the central and peripheral nervous systems. They are involved in learning, memory, anxiety, and the perception of pain. Gustducin is a G protein associated with taste and gustatory system. It plays a major role in sensation of bitter, sweet and umami stimuli.
-
This question is part of the following fields:
- Medicine
- Neurology
-
-
Question 100
Incorrect
-
The thalamic nuclei that project over wide regions of the neocortex are:
Your Answer:
Correct Answer: Specific relay nuclei
Explanation:The thalamus is considered the relay station for sensory and motor stimuli. There are three basic types of thalamic nuclei: relay nuclei, association nuclei and non-specific nuclei. Relay nuclei receive very well defined inputs and project this signal to functionally distinct areas of the cerebral cortex. These include the nuclei that relay primary sensations and also the nuclei involved in feedback of cerebellar signals and basal gangliar output.
-
This question is part of the following fields:
- Medicine
- Neurology
-
00
Correct
00
Incorrect
00
:
00
:
00
Session Time
00
:
00
Average Question Time (
Mins)