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  • Question 1 - The Mantoux test utilises what type of hypersensitivity reaction? ...

    Correct

    • The Mantoux test utilises what type of hypersensitivity reaction?

      Your Answer: Type IV

      Explanation:

      The Mantoux test is based on type IV hypersensitivity reaction.

    • This question is part of the following fields:

      • Immunology
      16
      Seconds

  • Question 2 - Which immunoglobulin is the first to be synthesised by the neonate? ...

    Correct

    • Which immunoglobulin is the first to be synthesised by the neonate?

      Your Answer: IgM

      Explanation:

      Fetal production of immunoglobulin begins early on at about 10 weeks gestation with the production of IgM antibodies. Maternal IgG, which is a key component of fetal immunity is passed on to the foetus through the placenta from 12 weeks of gestation. Secretory IgA is not produced until after birth, through breast milk.

    • This question is part of the following fields:

      • Immunology
      2.5
      Seconds

  • Question 3 - Macrophages are derived from what type of white blood cell? ...

    Correct

    • Macrophages are derived from what type of white blood cell?

      Your Answer: Monocytes

      Explanation:

      Macrophages are derived from monocytes. When monocytes come across a pathogen they differentiate into macrophages for phagocytosis to occur.

    • This question is part of the following fields:

      • Immunology
      1.8
      Seconds

  • Question 4 - Which of the following increases in pregnancy? ...

    Incorrect

    • Which of the following increases in pregnancy?

      Your Answer: Th1

      Correct Answer: Th2

      Explanation:

      T-Helper cells type 2 increase during pregnancy. They secret cytokines IL-4,5,9,10 and 13.

    • This question is part of the following fields:

      • Immunology
      9
      Seconds

  • Question 5 - At what stage of gestation does maternal immunoglobulin G transfer to the foetus...

    Correct

    • At what stage of gestation does maternal immunoglobulin G transfer to the foetus start?

      Your Answer: 12 weeks

      Explanation:

      Transportation of the maternal IgG through the placenta starts around the 12 week of gestation.

    • This question is part of the following fields:

      • Immunology
      4.4
      Seconds

  • Question 6 - Haemolytic Disease of the New-born falls into what type of hypersensitivity reaction? ...

    Correct

    • Haemolytic Disease of the New-born falls into what type of hypersensitivity reaction?

      Your Answer: Type II

      Explanation:

      It is classified under type II hypersensitivity reaction. Antibodies are formed against the rhesus antigen i.e. D antigen. Hence when the Antibody reacts with the antigen on the RBC it results in activation of the complement cascade leading to lysis.

    • This question is part of the following fields:

      • Immunology
      3.5
      Seconds

  • Question 7 - Which immunoglobulin provides passive immunity to the neonate? ...

    Correct

    • Which immunoglobulin provides passive immunity to the neonate?

      Your Answer: IgG

      Explanation:

      Passive immunity to the neonate is provided by immunoglobulin G (IgG) since it can be transferred through the placenta from mother to the foetus.
      IgA is transferred from mothers to offspring through breast milk.
      IgM molecular structure is too big to be filtered through the placental vasculature to the foetus. IgM is the first Ig to be synthesised by the neonate

    • This question is part of the following fields:

      • Immunology
      0.7
      Seconds

  • Question 8 - Which of the following cell types act as professional antigen presenter cells (APCs)...

    Correct

    • Which of the following cell types act as professional antigen presenter cells (APCs)

      Your Answer: Macrophages

      Explanation:

      Macrophages are the antigen presenting cells, they phagocytose the pathogen and after breaking them down present their protein structure to the B and T cells for a specific immune reaction to take place.

    • This question is part of the following fields:

      • Immunology
      9.9
      Seconds

  • Question 9 - You see a patient in antenatal clinic who is concerned that she has...

    Correct

    • You see a patient in antenatal clinic who is concerned that she has never had chicken pox and may catch it during pregnancy. You check her Varicella status and she is non-immune. She asks you about vaccination. What type of vaccine is the varicella vaccine?

      Your Answer: Attenuated

      Explanation:

      Varicella is a live vaccine. The recent RCOG green top guidelines suggest vaccine can be considered postpartum or pre pregnancy but NOT whilst pregnant. In the non-immune pregnant woman they should be advised to avoid contact with people with chickenpox or shingles and to contact a healthcare professional promptly if exposed. If they have a significant exposure VZIG should be offered as soon as possible.

    • This question is part of the following fields:

      • Immunology
      24.7
      Seconds

  • Question 10 - Rhesus D immunoglobin treatment utilises what class of antibody? ...

    Correct

    • Rhesus D immunoglobin treatment utilises what class of antibody?

      Your Answer: IgG

      Explanation:

      It utilizes the IgG class of the antibody.

    • This question is part of the following fields:

      • Immunology
      5.4
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Immunology (9/10) 90%
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