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  • Question 1 - Rhesus D immunoglobin treatment utilises what class of antibody? ...

    Correct

    • Rhesus D immunoglobin treatment utilises what class of antibody?

      Your Answer: IgG

      Explanation:

      It utilizes the IgG class of the antibody.

    • This question is part of the following fields:

      • Immunology
      8.5
      Seconds

  • Question 2 - Which immunoglobulin provides passive immunity to the neonate? ...

    Incorrect

    • Which immunoglobulin provides passive immunity to the neonate?

      Your Answer: IgM

      Correct Answer: IgG

      Explanation:

      Passive immunity to the neonate is provided by immunoglobulin G (IgG) since it can be transferred through the placenta from mother to the foetus.
      IgA is transferred from mothers to offspring through breast milk.
      IgM molecular structure is too big to be filtered through the placental vasculature to the foetus. IgM is the first Ig to be synthesised by the neonate

    • This question is part of the following fields:

      • Immunology
      12.7
      Seconds

  • Question 3 - Which of the following increases in pregnancy? ...

    Incorrect

    • Which of the following increases in pregnancy?

      Your Answer: IL-2

      Correct Answer: Th2

      Explanation:

      T-Helper cells type 2 increase during pregnancy. They secret cytokines IL-4,5,9,10 and 13.

    • This question is part of the following fields:

      • Immunology
      13.1
      Seconds

  • Question 4 - Which of the following cell types act as professional antigen presenter cells (APCs)...

    Correct

    • Which of the following cell types act as professional antigen presenter cells (APCs)

      Your Answer: Macrophages

      Explanation:

      Macrophages are the antigen presenting cells, they phagocytose the pathogen and after breaking them down present their protein structure to the B and T cells for a specific immune reaction to take place.

    • This question is part of the following fields:

      • Immunology
      10
      Seconds

  • Question 5 - You have just clerked in a patient on the labour ward who has...

    Correct

    • You have just clerked in a patient on the labour ward who has SLE. What type of hypersensitivity reaction is SLE an example of?

      Your Answer: Type III

      Explanation:

      SLE is a type III hypersensitivity reaction

    • This question is part of the following fields:

      • Immunology
      8
      Seconds

  • Question 6 - To avoid potential haemolysis, Anti D immunoglobulin should be administered to which of...

    Incorrect

    • To avoid potential haemolysis, Anti D immunoglobulin should be administered to which of the following?

      Your Answer: Rhesus negative mother, non-sensitised, fetal cord blood Rh negative

      Correct Answer: Rhesus negative mother, non-sensitised, fetal cord blood Rh positive

      Explanation:

      The Rhesus status of a mother is important in pregnancy and even abortion. The exposure of an Rh-negative mother exposed to Rh antigens from a positive foetus, will influence the development of anti-Rh antibodies. This may cause problems in subsequent pregnancies leading to haemolysis in the newborn. Rh Anti RhD- globulin is therefore given to non-sensitised Rh-negative mothers who give birth to Rh-positive children to prevent the formation of anti-Rh antibodies. Anti RhD globulin is not useful for already sensitized, or RhD positive mothers; its administration could result in maternal blood being bound and taken out of circulation.

    • This question is part of the following fields:

      • Immunology
      35.1
      Seconds

  • Question 7 - Macrophages are derived from what type of white blood cell? ...

    Incorrect

    • Macrophages are derived from what type of white blood cell?

      Your Answer: Natural Killer Cells

      Correct Answer: Monocytes

      Explanation:

      Macrophages are derived from monocytes. When monocytes come across a pathogen they differentiate into macrophages for phagocytosis to occur.

    • This question is part of the following fields:

      • Immunology
      10.3
      Seconds

  • Question 8 - Which of the following is a tumour marker for ovarian cancer? ...

    Correct

    • Which of the following is a tumour marker for ovarian cancer?

      Your Answer: Ca 125

      Explanation:

      CA-125 is the tumour marker specific for ovarian carcinoma.

    • This question is part of the following fields:

      • Immunology
      4.3
      Seconds

  • Question 9 - The Mantoux test utilises what type of hypersensitivity reaction? ...

    Correct

    • The Mantoux test utilises what type of hypersensitivity reaction?

      Your Answer: Type IV

      Explanation:

      The Mantoux test is based on type IV hypersensitivity reaction.

    • This question is part of the following fields:

      • Immunology
      4.1
      Seconds

  • Question 10 - Which Immunoglobulin (or antibody) is secreted in large amounts in breast milk? ...

    Incorrect

    • Which Immunoglobulin (or antibody) is secreted in large amounts in breast milk?

      Your Answer: IgM

      Correct Answer: IgA

      Explanation:

      When considering immunoglobulins in neonates. There are only a few key points you are likely to be tested on. 1. IgA is resistant to stomach acid and found in large amounts in breast milk. 2. IgG is the only Ig that can cross the placenta so is key for passive neonatal immunity 3. When the neonate starts synthesising its own Ig it is IgM that is produced first.

    • This question is part of the following fields:

      • Immunology
      6.6
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Immunology (5/10) 50%
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