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  • Question 1 - Endolymph in the inner ear is rich in: ...

    Incorrect

    • Endolymph in the inner ear is rich in:

      Your Answer: Ca

      Correct Answer: K

      Explanation:

      Cochlear fluids namely endolymph and perilymph have different compositions. Perilymph is a typical extracellular fluid, with ionic composition comparable to plasma or cerebrospinal fluid. The main cation is sodium. Endolymph is a totally unique extracellular fluid, with an ion composition unlike that which is found anywhere else in the body. The major cation in the endolymph is potassium and there is virtually no sodium.

    • This question is part of the following fields:

      • Neuro-anatomy
      5.5
      Seconds

  • Question 2 - Which afferent information is carried by the dorsal column? ...

    Incorrect

    • Which afferent information is carried by the dorsal column?

      Your Answer: Pain

      Correct Answer: Proprioception/ discriminative touch

      Explanation:

      The posterior grey column (dorsal column) is responsible for carrying the sensation of proprioception, two-point discrimination, and vibration to the nucleus proprius, situated anterior to the substantia gelatinosa throughout the spinal cord.

    • This question is part of the following fields:

      • Neuro-anatomy
      7.4
      Seconds

  • Question 3 - What happens first during depolarisation of the membrane potential? ...

    Incorrect

    • What happens first during depolarisation of the membrane potential?

      Your Answer: Gated Ca channel opens allowing the influx of Ca

      Correct Answer: Gated Na channels open allowing the influx of Na

      Explanation:

      Generation of an action potential in response to a stimulus is a result of a previously maintained resting membrane potential (RMP). Generation of resting membrane potential is mediated mainly by potassium ions. Several membrane proteins maintain RMP by transport of ions in and out of cell. Na+/K+ ATPase pump maintains a concentration gradient of Na+ and K+ ions. Na+ concentration in extracellular fluid is higher compared to intracellular fluid and K+ ion concentration is higher intracellularly. Generation of an action potential facilitates opening of Na+ ion channels which allow for Na+ to diffuse inside the cell according to the concentration gradient.

    • This question is part of the following fields:

      • Neuro-anatomy
      12.6
      Seconds

  • Question 4 - The premotor cortex is: ...

    Incorrect

    • The premotor cortex is:

      Your Answer: Brodmann area 4

      Correct Answer: Brodmann area 6

      Explanation:

      A Brodmann area in the brain is defined by cytoarchitecture, histology and organization of cells:
      Primary Sensory 3,1,2
      Primary Motor 4
      Premotor 6
      Primary Visual 17
      Primary Auditory 41
      Brocas 44

    • This question is part of the following fields:

      • Neuro-anatomy
      7
      Seconds

  • Question 5 - The outer and inner surfaces of the arachnoid mater is covered with: ...

    Incorrect

    • The outer and inner surfaces of the arachnoid mater is covered with:

      Your Answer: Ectodermal cells

      Correct Answer: Mesothelial cells

      Explanation:

      The arachnoid mater is one of the three meninges that covers the brain and spinal cord. It is interposed between the two other meninges, the more superficial and much thicker dura mater and the deeper pia mater, from which it is separated by the subarachnoid space. The arachnoid mater consists of a subdural mesothelial layer and a compact central layer

    • This question is part of the following fields:

      • Neuro-anatomy
      8.7
      Seconds

  • Question 6 - The consensual light reflex is co-ordinated mainly in the: ...

    Incorrect

    • The consensual light reflex is co-ordinated mainly in the:

      Your Answer: Superior nucleus

      Correct Answer: Edinger-Westphal nucleus

      Explanation:

      The consensual light reflex occurs when an individual’s right eye is shielded and light shines into the left eye, constriction of the right pupil will occur, as well as the left. This is because the afferent signal sent through one optic nerve connects to the Edinger-Westphal nucleus, whose axons run to both the right and the left oculomotor nerves.

    • This question is part of the following fields:

      • Neuro-anatomy
      17.2
      Seconds

  • Question 7 - Where do the spinothalamic axons decussate? ...

    Correct

    • Where do the spinothalamic axons decussate?

      Your Answer: Spinal cord

      Explanation:

      The second order neurons from the spinothalamic tract cross obliquely to the opposite side in the anterior grey and white commissure within one segment of the spinal cord.

    • This question is part of the following fields:

      • Neuro-anatomy
      5.8
      Seconds

  • Question 8 - The Afferent neuron that supplies all sensory elements of the muscle spindle is...

    Incorrect

    • The Afferent neuron that supplies all sensory elements of the muscle spindle is what type of sensory neuron?

      Your Answer: IIb

      Correct Answer: Ia

      Explanation:

      Muscle spindle is supplied by both sensory and motor nerves. Sensory supply is Type Ia fibers whereas motor supply is gamma motor neurone.

    • This question is part of the following fields:

      • Neuro-anatomy
      6.9
      Seconds

  • Question 9 - During which stage of sleep is muscle tone in the limbs most reduced?...

    Correct

    • During which stage of sleep is muscle tone in the limbs most reduced?

      Your Answer: REM

      Explanation:

      Rapid eye movement (REM) stage is marked by extensive physiological changes in the body, such as accelerated respiration, increased brain activity and muscle relaxation. People dream during REM sleep, perhaps as a result of excited brain activity and the paralysis of major voluntary muscles.

    • This question is part of the following fields:

      • Neuro-anatomy
      4.2
      Seconds

  • Question 10 - Which enzyme is responsible for the removal of acetylcholine from the synapse? ...

    Correct

    • Which enzyme is responsible for the removal of acetylcholine from the synapse?

      Your Answer: Acetylcholinesterase

      Explanation:

      Acetylcholinesterase is the enzyme that is responsible for breaking down acetylcholine into choline and acetate. Both of these molecules are transported back to the presynaptic neuron to be synthesized again. This enzyme is attached to the collagen fibers of the basement membrane in the synaptic cleft.

    • This question is part of the following fields:

      • Neuro-anatomy
      8.7
      Seconds

  • Question 11 - Transportation of proteins from the cell body to axonal terminals is known as:...

    Correct

    • Transportation of proteins from the cell body to axonal terminals is known as:

      Your Answer: Axoplasmic flow

      Explanation:

      Transportation of proteins from the cell body to axonal terminals is known as axoplasmic, axonal flow or Axonal transport.

    • This question is part of the following fields:

      • Neuro-anatomy
      9.7
      Seconds

  • Question 12 - The nucleus ambiguus: ...

    Incorrect

    • The nucleus ambiguus:

      Your Answer: Receives sensory input from the anterior 2/3 of the tongue via CN VII

      Correct Answer: Regulates swallowing, phonation and parasympathetic supply to the heart via CN IX, X and XI

      Explanation:

      Nucleus Ambiguus is a group of large motor neurons found deep in the medullary reticular formation. It contains cell bodies of nerves that are responsible for the innervation of muscles of speech and swallowing which are located in the soft palate, pharynx and larynx. Additionally, it contains cholinergic preganglionic parasympathetic neurons of the heart via CN X, IX and XI

    • This question is part of the following fields:

      • Neuro-anatomy
      6.2
      Seconds

  • Question 13 - Efferent innervation of the muscle spindle is supplied by which type of motor...

    Incorrect

    • Efferent innervation of the muscle spindle is supplied by which type of motor neuron?

      Your Answer: Delta – motor neuron

      Correct Answer: Gama – motor neuron

      Explanation:

      The muscle spindle is supplied by both sensory and motor nerves. Sensory supply is via Type Ia fibers whereas the motor supply is via gamma motor neurons.

    • This question is part of the following fields:

      • Neuro-anatomy
      13.1
      Seconds

  • Question 14 - The midbrain, medulla and pons, contain the following cranial nerve nuclei? ...

    Correct

    • The midbrain, medulla and pons, contain the following cranial nerve nuclei?

      Your Answer: CN 3 - 12

      Explanation:

      The cranial nerves (with the exception of I and II) originate in the brainstem, which includes the midbrain, the pons, and the medulla.

    • This question is part of the following fields:

      • Neuro-anatomy
      8.2
      Seconds

  • Question 15 - The ependyma fuse with which of the following to from the choroid plexus?...

    Incorrect

    • The ependyma fuse with which of the following to from the choroid plexus?

      Your Answer: Tentorium cerebella

      Correct Answer: Tela choroidea

      Explanation:

      The choroid plexus produces the cerebrospinal fluid (CSF) in the ventricles of the brain. It consists of modified ependymal cells. Tela choroidea is a region of pia mater of the meninges and underlying ependyma that’s a part of the choroid plexus. It is a very thin layer of the connective tissue of pia mater that overlies and covers the ependyma.

    • This question is part of the following fields:

      • Neuro-anatomy
      15.5
      Seconds

  • Question 16 - Choose the correct answer: The interposed nuclei… ...

    Incorrect

    • Choose the correct answer: The interposed nuclei…

      Your Answer: Are nuclei of the spinocerebellar functional division of the cerebellum

      Correct Answer: Are the emboliform and globose nuclei in the paravermis

      Explanation:

      The interposed nuclei are a part of deep cerebellar complex and are composed of the globose nucleus and the emboliform nucleus. It receives afferent fibers from the anterior lobe of the cerebellum and sends output via the superior cerebellar peduncle to the red nucleus.

    • This question is part of the following fields:

      • Neuro-anatomy
      0.4
      Seconds

  • Question 17 - Which neurotransmitter is made from hydroxylation and decarboxylation of tryptophan? ...

    Correct

    • Which neurotransmitter is made from hydroxylation and decarboxylation of tryptophan?

      Your Answer: Serotonin

      Explanation:

      Serotonin is synthesized from the essential amino acid tryptophan. The rate-limiting step is the conversion of the amino acid to 5-hydroxytryptophan by tryptophan hydroxylase. This is then converted to serotonin by the aromatic L-amino acid decarboxylase.

    • This question is part of the following fields:

      • Neuro-anatomy
      4.3
      Seconds

  • Question 18 - Regarding taste threshold and intensity discrimination: ...

    Incorrect

    • Regarding taste threshold and intensity discrimination:

      Your Answer: 50% change in concentration of substance tasted is necessary before an intensity difference can be detected

      Correct Answer: 30% change in concentration of substance tasted is necessary before an intensity difference can be detected

      Explanation:

      The ability of humans to differentiate differences in intensity of taste is poor. A 30% change in the concentration of the substance being tasted is required before an intensity difference is perceived.

    • This question is part of the following fields:

      • Neuro-anatomy
      12.6
      Seconds

  • Question 19 - Which part of the cerebellum is primarily responsible for equilibrium and eye movements?...

    Correct

    • Which part of the cerebellum is primarily responsible for equilibrium and eye movements?

      Your Answer: Vestibulocerebellum

      Explanation:

      The vestibulocerebellum develops at the same time as the vestibular apparatus in the inner ear. Its regulates balance between agonist and antagonist muscle contractions of the spine, hips, and shoulders during rapid movements.

    • This question is part of the following fields:

      • Neuro-anatomy
      5.4
      Seconds

  • Question 20 - The thalamic main input from the cortex is via which tracts? ...

    Incorrect

    • The thalamic main input from the cortex is via which tracts?

      Your Answer: Corticostriatal tracts

      Correct Answer: Thalamocortical pathway

      Explanation:

      The thalamus is connected to cerebral cortex via the thalamocortical radiation.

    • This question is part of the following fields:

      • Neuro-anatomy
      8.7
      Seconds

  • Question 21 - Which neuron secretes glutamate as its neurotransmitter? ...

    Correct

    • Which neuron secretes glutamate as its neurotransmitter?

      Your Answer: A delta and C pain fibers

      Explanation:

      A delta and C fibers use glutamate as their primary neurotransmitter where it acts as a fast acting localized neurotransmitter.

    • This question is part of the following fields:

      • Neuro-anatomy
      9.9
      Seconds

  • Question 22 - The primary auditory cortex is: ...

    Incorrect

    • The primary auditory cortex is:

      Your Answer: Brodmann area 17

      Correct Answer: Brodmann area 41

      Explanation:

      A Brodmann area in the brain is defined by cytoarchitecture, histology and organization of cells:
      Primary Sensory 3,1,2
      Primary Motor 4
      Premotor 6
      Primary Visual 17
      Primary Auditory 41
      Brocas 44

    • This question is part of the following fields:

      • Neuro-anatomy
      2.7
      Seconds

  • Question 23 - In the basal ganglia, the Lentiform nucleus is formed by which two nuclei?...

    Incorrect

    • In the basal ganglia, the Lentiform nucleus is formed by which two nuclei?

      Your Answer: Globus pallidus and subthalamus

      Correct Answer: Putamen and Globus pallidus

      Explanation:

      The Basal Ganglia are composed of the following structures: Caudate, putamen, Globus pallidus, subthalamic nucleus and substantia nigra. The lentiform nucleus comprises of the putamen and the Globus pallidus.

    • This question is part of the following fields:

      • Neuro-anatomy
      12.6
      Seconds

  • Question 24 - Which one of the following cells originates from a monocyte and resembles a...

    Incorrect

    • Which one of the following cells originates from a monocyte and resembles a macrophage?

      Your Answer: Astrocyte

      Correct Answer: Microglia

      Explanation:

      Microglia act as the macrophages of the central nervous system, and they contribute to innate and adaptive immune responses. Studies have shown that microglial cells recognize monocyte antigens, and there are similarities between them that demonstrate that they originate from these monocytes.

    • This question is part of the following fields:

      • Neuro-anatomy
      4.7
      Seconds

  • Question 25 - Which of the following is the smallest cell of the nervous system? ...

    Incorrect

    • Which of the following is the smallest cell of the nervous system?

      Your Answer: Schwann cell

      Correct Answer: Microglia

      Explanation:

      Microglia are the smallest of the neuroglial cells in the nervous system. They are scattered throughout the central nervous system and have phagocytic properties.

    • This question is part of the following fields:

      • Neuro-anatomy
      9.8
      Seconds

  • Question 26 - Which one of the following neurotransmitters is considered a monoamine? ...

    Incorrect

    • Which one of the following neurotransmitters is considered a monoamine?

      Your Answer: Norepinephrine

      Correct Answer: Acetylcholine

      Explanation:

      Acetylcholine is a major neurotransmitter in the peripheral nervous system. Monoamine neurotransmitters contain only one amino group joined to an aromatic ring. Acetylcholine is produced from acetyl-CoA and choline.

    • This question is part of the following fields:

      • Neuro-anatomy
      5.9
      Seconds

  • Question 27 - What landmark divides the frontal and parietal lobes? ...

    Incorrect

    • What landmark divides the frontal and parietal lobes?

      Your Answer: Calcarine sulcus

      Correct Answer: Central sulcus

      Explanation:

      The central sulcus divides the frontal lobe from the parietal lobe. It contains the motor cells for the movement function of the body.

    • This question is part of the following fields:

      • Neuro-anatomy
      19.8
      Seconds

  • Question 28 - The cerebellum consist of which three lobes? ...

    Incorrect

    • The cerebellum consist of which three lobes?

      Your Answer: Medial, lateral and flocculonodular

      Correct Answer: Anterior, posterior and flocculonodular

      Explanation:

      The cerebellum consists of 3 lobes; Anterior, Posterior and Flocculonodular lobe.

    • This question is part of the following fields:

      • Neuro-anatomy
      5
      Seconds

  • Question 29 - Into how many functional units can the cerebellum be divided? ...

    Correct

    • Into how many functional units can the cerebellum be divided?

      Your Answer: 3

      Explanation:

      The functional division of the cerebellum are the: Vestibulocerebellum (floculonodular lobe), Spinocerebellum (vermis and associated areas in the midline) and cerebrocerebellum (lateral hemispheres).

    • This question is part of the following fields:

      • Neuro-anatomy
      3.6
      Seconds

  • Question 30 - Regarding the innervation of the cerebral blood vessels, postganglionic sympathetic neurons have their...

    Incorrect

    • Regarding the innervation of the cerebral blood vessels, postganglionic sympathetic neurons have their cell bodies in the:

      Your Answer: Large arteries

      Correct Answer: Superior cervical ganglia

      Explanation:

      The superior cervical ganglion (SCG) is a part of autonomic system which plays a major role in maintaining homeostasis of the body. This ganglion innervates structures in the head and neck and is the largest and the most superiorly located ganglion. The SCG provides sympathetic innervation to structures within the head, including the pineal gland, the blood vessels in the cranial muscles and the brain, the choroid plexus, the eyes, the lacrimal glands, the carotid body, the salivary glands, and the thyroid gland. The postganglionic axons of the SCG innervate the internal carotid artery and form the internal carotid plexus. The internal carotid plexus carries the postganglionic axons of the SCG to the eye, lacrimal gland, mucous membranes of the mouth, nose, and pharynx, and numerous blood-vessels in the head.

    • This question is part of the following fields:

      • Neuro-anatomy
      13.1
      Seconds

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