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Question 1
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Question 2
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Question 3
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Question 4
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Which immunoglobulin is the first to be synthesised by the neonate?
Your Answer: IgG
Correct Answer: IgM
Explanation:Fetal production of immunoglobulin begins early on at about 10 weeks gestation with the production of IgM antibodies. Maternal IgG, which is a key component of fetal immunity is passed on to the foetus through the placenta from 12 weeks of gestation. Secretory IgA is not produced until after birth, through breast milk.
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This question is part of the following fields:
- Immunology
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Question 5
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Question 6
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Which of the following cell types act as professional antigen presenter cells (APCs)
Your Answer: Macrophages
Explanation:Macrophages are the antigen presenting cells, they phagocytose the pathogen and after breaking them down present their protein structure to the B and T cells for a specific immune reaction to take place.
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This question is part of the following fields:
- Immunology
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Question 7
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Fetal immunoglobulin production begins at what gestation?
Your Answer: Week 10
Explanation:Fetal production of immunoglobulin begins early on, at about 10 weeks gestation with the production of IgM antibodies. Maternal IgG, which is a key component of fetal immunity, is passed on to the foetus through the placenta from 12 weeks of gestation. Secretory IgA is not produced until after birth.
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This question is part of the following fields:
- Immunology
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Question 8
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Question 9
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You see a patient in antenatal clinic who is concerned that she has never had chicken pox and may catch it during pregnancy. You check her Varicella status and she is non-immune. She asks you about vaccination. What type of vaccine is the varicella vaccine?
Your Answer: Attenuated
Explanation:Varicella is a live vaccine. The recent RCOG green top guidelines suggest vaccine can be considered postpartum or pre pregnancy but NOT whilst pregnant. In the non-immune pregnant woman they should be advised to avoid contact with people with chickenpox or shingles and to contact a healthcare professional promptly if exposed. If they have a significant exposure VZIG should be offered as soon as possible.
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This question is part of the following fields:
- Immunology
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Question 10
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Average Question Time (
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