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  • Question 1 - What is the function of Activated protein C? ...

    Correct

    • What is the function of Activated protein C?

      Your Answer: Inactivates factor Va

      Explanation:

      Activated Protein C (APC) is a crucial protein in the regulation of blood coagulation. Its primary functions include:

      1. Inactivating Factor Va: APC inactivates Factor Va, which is a cofactor for the conversion of prothrombin to thrombin by Factor Xa. By inactivating Factor Va, APC reduces thrombin formation, thereby acting as an anticoagulant.
      2. Inactivating Factor VIIIa: APC also inactivates Factor VIIIa, another cofactor that assists Factor IXa in the conversion of Factor X to Factor Xa. This further contributes to its anticoagulant effect.

      These actions help to regulate blood clotting and prevent excessive thrombosis.

    • This question is part of the following fields:

      • Haematology
      • Medicine
      11.3
      Seconds

  • Question 2 - Choose the correct statement regarding the protein C/S system? ...

    Correct

    • Choose the correct statement regarding the protein C/S system?

      Your Answer: The protein C/S complex inactivates factor Va and VIIIa

      Explanation:

      The best characterized function of Protein S is its role in the anti coagulation pathway, where it functions as a cofactor to Protein C in the inactivation of Factors Va and VIIIa.

    • This question is part of the following fields:

      • Haematology
      • Medicine
      9.2
      Seconds

  • Question 3 - In the normal adult, haematopoiesis is present ...

    Correct

    • In the normal adult, haematopoiesis is present

      Your Answer: Axial skeleton and proximal ends of long bones

      Explanation:

      In children, haematopoiesis occurs in the marrow of the long bones such as the femur and tibia. In adults, it occurs mainly in the pelvis, cranium, vertebrae, and sternum.

    • This question is part of the following fields:

      • Haematology
      • Medicine
      3.8
      Seconds

  • Question 4 - Which enzyme deficiency causes pellagra? ...

    Correct

    • Which enzyme deficiency causes pellagra?

      Your Answer: Niacin

      Explanation:

      Pellagra is a vitamin deficiency disease most frequently caused by a chronic lack of niacin (vitamin B3) in the diet.

    • This question is part of the following fields:

      • Haematology
      • Medicine
      3.5
      Seconds

  • Question 5 - Which of the following vitamin deficiencies is associated with xerophthalmia? ...

    Correct

    • Which of the following vitamin deficiencies is associated with xerophthalmia?

      Your Answer: Vitamin A

      Explanation:

      Xerophthalmia caused by a severe vitamin A deficiency is described by pathologic dryness of the conjunctiva and cornea. The conjunctiva becomes dry, thick and wrinkled. If untreated, it can lead to corneal ulceration and ultimately to blindness as a result of corneal damage.

    • This question is part of the following fields:

      • Haematology
      • Medicine
      3.4
      Seconds

  • Question 6 - Which vitamin plays a major role in the metabolism of many amino acids?...

    Correct

    • Which vitamin plays a major role in the metabolism of many amino acids?

      Your Answer: Vitamin B6

      Explanation:

      Vitamin B6 is part of the vitamin B group, and its active form, pyridoxal 5′-phosphate (PLP) serves as a coenzyme in many enzyme reactions in amino acid, glucose, and lipid metabolism.

    • This question is part of the following fields:

      • Haematology
      • Medicine
      2.9
      Seconds

  • Question 7 - Which vitamin is found in NAD and NADP? ...

    Correct

    • Which vitamin is found in NAD and NADP?

      Your Answer: Vitamin B3

      Explanation:

      In organisms, NAD can be synthesized from simple building-blocks (de novo) from the amino acids tryptophan or aspartic acid. In an alternative fashion, more complex components of the coenzymes are taken up from food as the vitamin called niacin (vitamin B3)

    • This question is part of the following fields:

      • Haematology
      • Medicine
      8.9
      Seconds

  • Question 8 - The following occurs as a result of 2,3 Bisphosphoglycerate binding to deoxyhaemoglobin ...

    Correct

    • The following occurs as a result of 2,3 Bisphosphoglycerate binding to deoxyhaemoglobin

      Your Answer: A reduction in deoxyhaemoglobin's affinity for oxygen

      Explanation:

      2,3-BPG acts as a heteroallosteric effector of haemoglobin, lowering haemoglobin’s affinity for oxygen by binding preferentially to deoxyhaemoglobin. An increased concentration of BPG in red blood cells favours formation of the T, low-affinity state of haemoglobin and so the oxygen-binding curve will shift to the right.

    • This question is part of the following fields:

      • Haematology
      • Medicine
      4.7
      Seconds

  • Question 9 - The spleen underlies which ribs? ...

    Correct

    • The spleen underlies which ribs?

      Your Answer: 9 through 11

      Explanation:

      The spleen lies between the 9th and 11th ribs on the left hand side.

    • This question is part of the following fields:

      • Haematology
      • Medicine
      2.3
      Seconds

  • Question 10 - Bone marrow barrier is important to: ...

    Correct

    • Bone marrow barrier is important to:

      Your Answer: Allow mature red blood cells to pass into circulation

      Explanation:

      The blood vessels of the bone marrow constitute a barrier, inhibiting immature blood cells from leaving the marrow. Only mature blood cells contain the membrane proteins, such as aquaporin and glycophorin, that are required to attach to and pass the blood vessel endothelium.

    • This question is part of the following fields:

      • Haematology
      • Medicine
      4.5
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Haematology (10/10) 100%
Medicine (10/10) 100%
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