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  • Question 1 - The collection of genes that are termed the major histocompatibility complex (MHC) are...

    Correct

    • The collection of genes that are termed the major histocompatibility complex (MHC) are found on:

      Your Answer: Short arm of chromosome 6

      Explanation:

      Histocompatibility, or tissue compatibility, is the property of having the same, or sufficiently similar, alleles of a set of genes called human leukocyte antigens (HLA). HLA is the human form of the major histocompatibility complex (MHC) genes found in all vertebrates. On a population level there is a great number of different alleles at each HLA locus on the short arm of chromosome 6

    • This question is part of the following fields:

      • Immunology
      • Medicine
      24.5
      Seconds

  • Question 2 - The immunoglobulin found in the highest concentration in humans is ...

    Correct

    • The immunoglobulin found in the highest concentration in humans is

      Your Answer: IgG

      Explanation:

      Representing approximately 75% of serum antibodies in humans, IgG is the most common type of antibody found in the circulation. IgG molecules are created and released by plasma B cells.

    • This question is part of the following fields:

      • Immunology
      • Medicine
      6.4
      Seconds

  • Question 3 - Arachidonic acid is converted to: ...

    Correct

    • Arachidonic acid is converted to:

      Your Answer: Prostaglandin H2

      Explanation:

      The enzymes cyclooxygenase-1 and -2 (i.e. prostaglandin G/H synthase 1 and 2 {PTGS1 and PTGS2}) metabolize arachidonic acid to Prostaglandin G2 and prostaglandin H2.

    • This question is part of the following fields:

      • Immunology
      • Medicine
      21.2
      Seconds

  • Question 4 - The predominant site in the lymph node where T lymphocytes are found is:...

    Correct

    • The predominant site in the lymph node where T lymphocytes are found is:

      Your Answer: Paracortex

      Explanation:

      Paracortex is found between the cortex and the medulla and it is composed of a non-nodular type of arrangement that is mostly made up of T cells.

    • This question is part of the following fields:

      • Immunology
      • Medicine
      10.2
      Seconds

  • Question 5 - Which of the following substances is involved in the respiratory burst by the...

    Correct

    • Which of the following substances is involved in the respiratory burst by the neutrophil?

      Your Answer: NADPh oxidase

      Explanation:

      The respiratory burst is a rapid release of reactive oxygen species (ROS) from neutrophils and other phagocytes. This process is crucial for the destruction of pathogens. The key components and enzymes involved in the respiratory burst include:

      1. NADPH oxidase: This enzyme complex plays a central role in the respiratory burst by converting oxygen (O2) into superoxide anion (O2•-), a reactive oxygen species. This is the initial step in the production of various ROS.
      2. Superoxide dismutase (SOD): This enzyme converts superoxide anion (O2•-) into hydrogen peroxide (H2O2). While SOD is involved in the pathway, the respiratory burst is initiated by NADPH oxidase.
      3. Myeloperoxidase (MPO): This enzyme uses hydrogen peroxide (H2O2) to produce hypochlorous acid (HOCl) from chloride ions (Cl-), which is a potent antimicrobial agent. Myeloperoxidase also produces other reactive species using halide ions.
      4. Catalase: This enzyme degrades hydrogen peroxide (H2O2) into water (H2O) and oxygen (O2). While catalase helps to protect the cell from oxidative damage by breaking down H2O2, it is not involved in the generation of ROS during the respiratory burst.
      5. Adenylate cyclase: This enzyme is involved in the production of cyclic AMP (cAMP) from ATP and is not directly related to the respiratory burst.

    • This question is part of the following fields:

      • Immunology
      • Medicine
      21.7
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Immunology (5/5) 100%
Medicine (5/5) 100%
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