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Question 1
Correct
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Which immunological cells are predominant in the lymph node (almost 98 % residence)?
Your Answer: Lymphocytes
Explanation:Lymph nodes are a lymphoid organ mostly consisting of lymphocytes: B cells in the cortex from where they mature and proliferate and T cells in the paracortex. The medulla is also composed of lymphocytes and macrophages.
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This question is part of the following fields:
- Immunology
- Medicine
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Question 2
Correct
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Arachidonic acid is converted to:
Your Answer: Prostaglandin H2
Explanation:The enzymes cyclooxygenase-1 and -2 (i.e. prostaglandin G/H synthase 1 and 2 {PTGS1 and PTGS2}) metabolize arachidonic acid to Prostaglandin G2 and prostaglandin H2.
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This question is part of the following fields:
- Immunology
- Medicine
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Question 3
Correct
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Question 4
Incorrect
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Which cells produce the immunoglobulin proteins involved in mediating humoral immunity?
Your Answer: Memory B cell
Correct Answer: Differentiated forms of B lymphocytes known as plasma cells
Explanation:After the B cells have been activated by a certain antigens, they transform into plasma cells. These plasma cells are responsible for the generation of antibodies (or immunoglobulins Ig) which are also known as regulators of humoral immunity. There are fives classes of Ig: IgA, IgG, IgM, IgE and IgD
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This question is part of the following fields:
- Immunology
- Medicine
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Question 5
Incorrect
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What is the name of the area that indicates the site of active B lymphocyte proliferation?
Your Answer: Cortex
Correct Answer: Germinal centre
Explanation:The cortex of the lymph node consists of the lymphoid nodules and sinusoids and posses a germinal centre from which B cells proliferate.
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This question is part of the following fields:
- Immunology
- Medicine
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Question 6
Correct
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The process whereby bacterial products interact with plasma factors and cells to produce agents that attract neutrophils to an infected area is called:
Your Answer: Chemotaxis
Explanation:During an inflammatory process many cytokines are produced that act as chemokines to attract neutrophils to the site of inflammation. These include bacterial products, IL-8, C5a and LTB4.
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This question is part of the following fields:
- Immunology
- Medicine
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Question 7
Correct
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Cells mediating innate immunity include:
Your Answer: Natural killer cells
Explanation:Natural killer cells have features of both innate and adaptive immunity. They play an important part in defence against tumours and viruses. They are non specific and do not generate immunological memory
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This question is part of the following fields:
- Immunology
- Medicine
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Question 8
Correct
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In both innate and humoral immunity, receptors involved recognize:
Your Answer: The shape of the antigen
Explanation:Antigen receptors recognize the shape of the antigen. They identify specific epitopes and are found on T cells.
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This question is part of the following fields:
- Immunology
- Medicine
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Question 9
Correct
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Question 10
Correct
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Tumour necrosis factor is a cytokine. What is its major function?
Your Answer: Promotion of inflammation
Explanation:Tumour necrosis factor (TNF) is a cytokine that has a wide variety of functions. It can cause cytolysis of certain tumour cell lines; it is involved in the induction of cachexia; it is a potent pyrogen, causing fever by direct action or by stimulation of interleukin-1 secretion; it can stimulate cell proliferation and induce cell differentiation under certain conditions.
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This question is part of the following fields:
- Immunology
- Medicine
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