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  • Question 1 - Eosinophils provide immunity against ...

    Correct

    • Eosinophils provide immunity against

      Your Answer: Multi cellular parasites

      Explanation:

      Eosinophils, are a variety of white blood cells and one of the immune system components responsible for combating multicellular parasites and certain infections in vertebrates.

    • This question is part of the following fields:

      • Immunology
      • Medicine
      4.5
      Seconds

  • Question 2 - Which of the following cells release histamines when they are activated by binding...

    Incorrect

    • Which of the following cells release histamines when they are activated by binding of specific antigens to cell fixed IgE molecules?

      Your Answer: Monocytes

      Correct Answer: Basophils

      Explanation:

      Mast cells and basophils both contain granules of vasoactive histamine in their cytosol. Both of them express IgE receptors on their cell surface and upon binding with a specific antigen they release their cytokines including histamine.

    • This question is part of the following fields:

      • Immunology
      • Medicine
      7.2
      Seconds

  • Question 3 - Cells mediating innate immunity include: ...

    Incorrect

    • Cells mediating innate immunity include:

      Your Answer: T lymphocytes

      Correct Answer: Natural killer cells

      Explanation:

      Natural killer cells have features of both innate and adaptive immunity. They play an important part in defence against tumours and viruses. They are non specific and do not generate immunological memory

    • This question is part of the following fields:

      • Immunology
      • Medicine
      14.8
      Seconds

  • Question 4 - Cell mediating innate immunity include: ...

    Correct

    • Cell mediating innate immunity include:

      Your Answer: Natural killer cells

      Explanation:

      Antigen receptors recognize the shape of the antigen. They identify specific epitopes and are found on T cells.

    • This question is part of the following fields:

      • Immunology
      • Medicine
      2.7
      Seconds

  • Question 5 - The predominant site in the lymph node where B lymphocytes are found is:...

    Incorrect

    • The predominant site in the lymph node where B lymphocytes are found is:

      Your Answer: Marginal sinus

      Correct Answer: Cortex

      Explanation:

      The cortex of the lymph node consists of the lymphoid nodules and sinusoids and posses a germinal centre from which B cells proliferate. The cortex of the lymph node predominately consists of B cells.

    • This question is part of the following fields:

      • Immunology
      • Medicine
      2.7
      Seconds

  • Question 6 - The cytoplasmic form of superoxide dismutase [SOD] contains: ...

    Incorrect

    • The cytoplasmic form of superoxide dismutase [SOD] contains:

      Your Answer: Cl

      Correct Answer: Zn and Cu

      Explanation:

      The cytoplasmic form of superoxide dismutase [SOD] contains zinc and copper

    • This question is part of the following fields:

      • Immunology
      • Medicine
      1.9
      Seconds

  • Question 7 - HLA class III genes encode for ...

    Incorrect

    • HLA class III genes encode for

      Your Answer: HLA-dr

      Correct Answer: Complement

      Explanation:

      HLAs corresponding to MHC class III encode components of the complement system.

    • This question is part of the following fields:

      • Immunology
      • Medicine
      3.8
      Seconds

  • Question 8 - What is the function of the acute phase protein, C-reactive protein? ...

    Incorrect

    • What is the function of the acute phase protein, C-reactive protein?

      Your Answer: Activates complement

      Correct Answer: Opsonises bacteria

      Explanation:

      There are various immune reactions that become activated once the barrier between the body and environment has been compromised. There are certain opsonins that bind to the bacteria and facilitate phagocytosis. One of them is the acute phase protein: C protein. others include antibodies and complement.

    • This question is part of the following fields:

      • Immunology
      • Medicine
      7
      Seconds

  • Question 9 - Which of the following substances is involved in the respiratory burst by the...

    Incorrect

    • Which of the following substances is involved in the respiratory burst by the neutrophil?

      Your Answer: Catalase degrades h2o2 to h20 and o2

      Correct Answer: NADPh oxidase

      Explanation:

      The respiratory burst is a rapid release of reactive oxygen species (ROS) from neutrophils and other phagocytes. This process is crucial for the destruction of pathogens. The key components and enzymes involved in the respiratory burst include:

      1. NADPH oxidase: This enzyme complex plays a central role in the respiratory burst by converting oxygen (O2) into superoxide anion (O2•-), a reactive oxygen species. This is the initial step in the production of various ROS.
      2. Superoxide dismutase (SOD): This enzyme converts superoxide anion (O2•-) into hydrogen peroxide (H2O2). While SOD is involved in the pathway, the respiratory burst is initiated by NADPH oxidase.
      3. Myeloperoxidase (MPO): This enzyme uses hydrogen peroxide (H2O2) to produce hypochlorous acid (HOCl) from chloride ions (Cl-), which is a potent antimicrobial agent. Myeloperoxidase also produces other reactive species using halide ions.
      4. Catalase: This enzyme degrades hydrogen peroxide (H2O2) into water (H2O) and oxygen (O2). While catalase helps to protect the cell from oxidative damage by breaking down H2O2, it is not involved in the generation of ROS during the respiratory burst.
      5. Adenylate cyclase: This enzyme is involved in the production of cyclic AMP (cAMP) from ATP and is not directly related to the respiratory burst.

    • This question is part of the following fields:

      • Immunology
      • Medicine
      4.5
      Seconds

  • Question 10 - Where does control of self-reactive T cells (self-tolerance) initially occur? ...

    Incorrect

    • Where does control of self-reactive T cells (self-tolerance) initially occur?

      Your Answer: Liver

      Correct Answer: Thymus

      Explanation:

      The thymus provides an inductive environment for development of T cells from hematopoietic progenitor cells. In addition, thymic stromal cells allow for the selection of a functional and self-tolerant T cell repertoire. Therefore, one of the most important roles of the thymus is the induction of central tolerance.

    • This question is part of the following fields:

      • Immunology
      • Medicine
      6.6
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Immunology (9/10) 90%
Medicine (9/10) 90%
Passmed
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