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Question 1
Correct
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The only APCs that can activate naive T lymphocytes are:
Your Answer: Dendric cells
Explanation:Only professional antigen-presenting cells (macrophages, B lymphocytes, and dendritic cells) are able to activate a resting helper T-cell when the matching antigen is presented. However, macrophages and B cells can only activate memory T cells whereas dendritic cells can activate both memory and naive T cells, and are the most potent of all the antigen-presenting cells.
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This question is part of the following fields:
- Immunology
- Medicine
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Question 2
Correct
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Question 3
Incorrect
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In both innate and humoral immunity, receptors involved recognize:
Your Answer: The specific chemical composition and the shape of the antigen
Correct Answer: The shape of the antigen
Explanation:Antigen receptors recognize the shape of the antigen. They identify specific epitopes and are found on T cells.
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This question is part of the following fields:
- Immunology
- Medicine
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Question 4
Correct
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Which immunological cells are predominant in the lymph node (almost 98 % residence)?
Your Answer: Lymphocytes
Explanation:Lymph nodes are a lymphoid organ mostly consisting of lymphocytes: B cells in the cortex from where they mature and proliferate and T cells in the paracortex. The medulla is also composed of lymphocytes and macrophages.
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This question is part of the following fields:
- Immunology
- Medicine
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Question 5
Correct
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What is the function of the acute phase protein, C-reactive protein?
Your Answer: Opsonises bacteria
Explanation:There are various immune reactions that become activated once the barrier between the body and environment has been compromised. There are certain opsonins that bind to the bacteria and facilitate phagocytosis. One of them is the acute phase protein: C protein. others include antibodies and complement.
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This question is part of the following fields:
- Immunology
- Medicine
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Question 6
Incorrect
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Eosinophils provide immunity against
Your Answer: Allergens
Correct Answer: Multi cellular parasites
Explanation:Eosinophils, are a variety of white blood cells and one of the immune system components responsible for combating multicellular parasites and certain infections in vertebrates.
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This question is part of the following fields:
- Immunology
- Medicine
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Question 7
Incorrect
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Neutrophils are key components of the innate immune system. They contain numerous primary and secondary granules involved in killing and digesting microorganisms. With regard to defensins, they are:
Your Answer: Involved in the breakdown of fibrous structures in the extracellular matrix
Correct Answer: Naturally occurring cysteine-rich antibacterial and antifungal polypeptides
Explanation:Cationic antimicrobial peptides, including defensins, cathelicidins, and thrombocidins, provide important initial defences against invading microbes. These peptides bind the bacterial membrane and form pores, killing the bacterium by hypo-osmotic lysis.
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This question is part of the following fields:
- Immunology
- Medicine
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Question 8
Correct
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Amongst the following cells, which is responsible for the secretion of defensins?
Your Answer: Neutrophils
Explanation:Eosinophils are phagocytic and they are directed against helminths. Basophils are involved in allergic reactions and contain histamine and vasoactive granules in their cytoplasm. Mast cells are similar to basophils. Monocytes differentiate into macrophages in the tissue, secret interleukins and are phagocytic. Neutrophils are phagocytic but are also responsible for secreting defensins.
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This question is part of the following fields:
- Immunology
- Medicine
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Question 9
Correct
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The predominant site in the lymph node where T lymphocytes are found is:
Your Answer: Paracortex
Explanation:Paracortex is found between the cortex and the medulla and it is composed of a non-nodular type of arrangement that is mostly made up of T cells.
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This question is part of the following fields:
- Immunology
- Medicine
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Question 10
Incorrect
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Neutrophils are attracted to an infected area by:
Your Answer: Cytokines
Correct Answer: Chemokines
Explanation:The major role of chemokines is to act as a chemoattractant to guide the migration of cells like neutrophils to the site of infection.
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This question is part of the following fields:
- Immunology
- Medicine
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