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  • Question 1 - An operation to remove a segment of the oesophagus through a right thoracotomy...

    Correct

    • An operation to remove a segment of the oesophagus through a right thoracotomy is complicated when a tear develops in a large venous structure in the posterior mediastinum that empties into the superior vena cava. Which of the following structures is likely to be injured?

      Your Answer: Azygos vein

      Explanation:

      The azygos vein is formed by the union of the right subcostal veins and the ascending lumbar veins at the level of the 12th thoracic vertebra. It enters the thorax through the aortic hiatus to ascend in the posterior mediastinum and arching over the right main bronchus posteriorly at the root of the right lung to join the superior vena cava before it pierces the pericardium.

      The basilic vein is a vein on the medial aspect of the arm that ascends to become the axillary vein.

      The cephalic vein is also a vein of the arm.

      The external jugular and brachiocephalic vein are not in the posterior mediastinum.

      The median cubital vein is found in the cubital fossa of the arm.

    • This question is part of the following fields:

      • Anatomy
      • Thorax
      182
      Seconds
  • Question 2 - Which of the following abnormalities can be seen in patients with hypermagnesemia? ...

    Incorrect

    • Which of the following abnormalities can be seen in patients with hypermagnesemia?

      Your Answer: Generalised seizures

      Correct Answer: Respiratory depression

      Explanation:

      Hypermagnesemia is an electrolyte disturbance in which there is a high level of magnesium in the blood. It is defined as a level greater than 1.1 mmol/L. Symptoms include weakness, confusion, decreased breathing rate, and cardiac arrest.

    • This question is part of the following fields:

      • Fluids & Electrolytes
      • Pathology
      40.7
      Seconds
  • Question 3 - A patient who following 20 years of working in the asbestos industry develops...

    Correct

    • A patient who following 20 years of working in the asbestos industry develops malignant mesothelioma and is scheduled for pleuropneumonectomy to remove the entire pleura and lung on the affected side. Which layer would provide a natural cleavage plane for surgical separation of the costal pleura from the thoracic wall?

      Your Answer: Endothoracic fascia

      Explanation:

      The endothoracic fascia is connective tissue that is between the costal parietal pleura and the inner aspect of the chest wall. Removing this layer of connective tissue would make it easy to separate the costal pleura from the thoracic wall.

      Deep fascia: is not found around the lungs. It is a layer of connective tissue that invests a muscle or a group of muscles.

      Parietal pleura: part of the pleura that lines the inner surface of the chest/thoracic cavity.

      Visceral pleura: is the serous membrane that lines the surface of the lungs.

      Transversus thoracis muscle fascia is associated only with the muscle transversus thoracis.

      Peritracheal fascia: a layer of connective tissue that invests the trachea. It is not associated with the thoracic wall or the costal pleura.

    • This question is part of the following fields:

      • Anatomy
      • Thorax
      381.8
      Seconds
  • Question 4 - Causes of metabolic acidosis with a normal anion gap include: ...

    Incorrect

    • Causes of metabolic acidosis with a normal anion gap include:

      Your Answer: Diabetic ketoacidosis

      Correct Answer: Diarrhoea

      Explanation:

      Excess acid intake and excess bicarbonate loss as in diarrhoea, are causes of metabolic acidosis with a normal anion gap. The other conditions all result in an increased anion gap.

    • This question is part of the following fields:

      • Fluids & Electrolytes
      • Physiology
      116.3
      Seconds
  • Question 5 - A 27-yeaar-old woman is diagnosed with candidiasis and prescribed fluconazole. What is the...

    Correct

    • A 27-yeaar-old woman is diagnosed with candidiasis and prescribed fluconazole. What is the mechanism of action of fluconazole?

      Your Answer: Inhibits cytochrome P450

      Explanation:

      Fluconazole is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections. Like other imidazole- and triazole-class antifungals, fluconazole inhibits the fungal cytochrome P450 enzyme, 14-demethylase. It is used to treat candidiasis, blastomycosis, coccidioidomycosis, cryptococcosis, histoplasmosis, dermatophytosis, and pityriasis versicolor.

    • This question is part of the following fields:

      • Pathology
      • Pharmacology
      25
      Seconds
  • Question 6 - Which of the following is NOT a Gram-negative rod? ...

    Incorrect

    • Which of the following is NOT a Gram-negative rod?

      Your Answer: Pseudomonas

      Correct Answer: Clostridium tetani

      Explanation:

      Gram-positive rods include Clostridia, Listeria and diphtheroids.

      Gram-negative rods include Escherichia coli, Klebsiella, Yersinia, Haemohilus, Pseudomonas, Shigella, Legionella, proteus and Salmonella

    • This question is part of the following fields:

      • Microbiology
      • Pathology
      95.5
      Seconds
  • Question 7 - Which muscle would be affected most following injury to the transverse cervical artery?...

    Incorrect

    • Which muscle would be affected most following injury to the transverse cervical artery?

      Your Answer: Levator scapulae

      Correct Answer: Trapezius

      Explanation:

      The latissimus dorsi receives blood from the thoracodorsal artery, the supraspinatus receives its blood from the suprascapular artery, the levator scapulae and the rhomboids are supplied by the dorsal scapular artery and the transverse cervical artery supplies blood to the trapezius.

    • This question is part of the following fields:

      • Anatomy
      • Upper Limb
      162.7
      Seconds
  • Question 8 - Vincristine is a chemotherapy agent used to treat a number of types of...

    Correct

    • Vincristine is a chemotherapy agent used to treat a number of types of cancer. Which of the following is a recognised major side-effect of vincristine?

      Your Answer: Peripheral neuropathy

      Explanation:

      Vincristine is an alkaloid chemotherapeutic agent. It is used to treat a number of types of cancer including acute lymphocytic leukaemia, acute myeloid leukaemia, Hodgkin’s disease, neuroblastoma, and small cell lung cancer among others. The main side-effects of vincristine are peripheral neuropathy and constipation.

    • This question is part of the following fields:

      • Pathology
      • Pharmacology
      17.6
      Seconds
  • Question 9 - Which of the following diseases affects young adults, causing pain in any bone...

    Incorrect

    • Which of the following diseases affects young adults, causing pain in any bone -particularly long bones- which worsens at night, and is typically relieved by common analgesics, such as aspirin?

      Your Answer: Ewing’s sarcoma

      Correct Answer: Osteoid osteoma

      Explanation:

      Osteoid osteoma, which tends to affect young adults, can occur in any bone but is most common in long bones. It can cause pain (usually worse at night) that is typically relieved by mild analgesics, such as non-steroidal anti-inflammatory drugs. X-ray findings include a small radiolucent zone surrounded by a larger sclerotic zone.

    • This question is part of the following fields:

      • Orthopaedics
      • Pathology
      105.9
      Seconds
  • Question 10 - What's the nodal stage of a testicular seminoma if several lymph nodes between...

    Incorrect

    • What's the nodal stage of a testicular seminoma if several lymph nodes between 2cm and 5cm are found?

      Your Answer: N3

      Correct Answer: N2

      Explanation:

      According to the American Joint Committee on Cancer (AJCC) 2002 guidelines, the nodal staging of testicular seminoma is the following:

      N0: no regional lymph node metastases

      N1: metastasis with lymph nodes 2 cm or less in their greatest dimension or multiple lymph nodes, none more than 2 cm

      N2: metastasis with lymph nodes greater than 2 cm but not greater than 5 cm in their greatest dimension, or multiple lymph nodes, any one mass greater than 2 cm, but not more than 5 cm

      N3: metastasis with lymph nodes greater than 5 cm in their greatest dimension.

      The patient in this case has N2 testicular seminoma. This TNM staging is extremely important because treatment options are decided depending on this classification.

    • This question is part of the following fields:

      • Pathology
      • Urology
      74.1
      Seconds
  • Question 11 - Intracellular shifting of hydrogen ions can generate a metabolic alkalosis. In which of...

    Correct

    • Intracellular shifting of hydrogen ions can generate a metabolic alkalosis. In which of the following conditions is metabolic alkalosis caused by this mechanism ?

      Your Answer: Hypokalaemia

      Explanation:

      Metabolic alkalosis is characterized by a primary increase in the concentration of serum bicarbonate ions. This may occur as a consequence of a loss of hydrogen ions or a gain in bicarbonate. Hydrogen ions may be lost through the kidneys or the GI tract, as for example during vomiting, nasogastric suction or use of diuretics. Intracellular shifting of hydrogen ions develops mainly during hypokalaemia to maintain neutrality. Gain in bicarbonate ions may develop during administration of sodium bicarbonate in high amounts or in amounts that exceed the capacity of excretion of the kidneys, as seen in renal failure. Fluid losses may be another cause of metabolic alkalosis, causing the reduction of extracellular fluid volume.

    • This question is part of the following fields:

      • Fluids & Electrolytes
      • Pathology
      267.7
      Seconds
  • Question 12 - A patient presents with loss of pain and temperature sensation in the left...

    Incorrect

    • A patient presents with loss of pain and temperature sensation in the left leg. He is likely to have a lesion involving:

      Your Answer: Left lateral spinothalamic tract

      Correct Answer: Right lateral spinothalamic tract

      Explanation:

      The spinothalamic tract is a sensory pathway originating in the spinal cord that transmits information to the thalamus. There are two main parts of the spinothalamic tract: the lateral spinothalamic tract transmits pain and temperature and the anterior spinothalamic tract transmits touch (crude touch). The decussation of this pathway occurs at the level of the spinal cord. Hence, a unilateral lesion of the lateral spinothalamic tract causes contralateral loss of pain and temperature.

    • This question is part of the following fields:

      • Neurology
      • Physiology
      69.9
      Seconds
  • Question 13 - Regarding innervation to the peroneus brevis muscle: ...

    Incorrect

    • Regarding innervation to the peroneus brevis muscle:

      Your Answer: Could be damaged by a fracture of the tibia

      Correct Answer: Could be damaged by a fracture of the neck of the fibula

      Explanation:

      The peroneus brevis is supplied by the fourth and fifth lumbar and first sacral nerves through the superficial peroneal nerve which is one of the two terminal branches of the common peroneal nerve. The common peroneal nerve winds around the neck of the fibula and can be injured in cases of fractured neck of fibula.

    • This question is part of the following fields:

      • Anatomy
      • Lower Limb
      128.9
      Seconds
  • Question 14 - The normal location of the major duodenal papilla: ...

    Correct

    • The normal location of the major duodenal papilla:

      Your Answer: Descending part of the duodenum

      Explanation:

      The major duodenal papilla is on the descending portion of the duodenum on the medial side, about 7-10cm from the pylorus. The pancreatic ducts and the common bile ducts unite and open by a common orifice on the summit of the duodenal papilla.

    • This question is part of the following fields:

      • Abdomen
      • Anatomy
      29.7
      Seconds
  • Question 15 - A 55 year-old construction worker is diagnosed with malignant mesothelioma. Exposure to which...

    Correct

    • A 55 year-old construction worker is diagnosed with malignant mesothelioma. Exposure to which substance increased his risk in developing mesothelioma?

      Your Answer: Asbestos

      Explanation:

      Mesothelioma is a rare, aggressive form of cancer that develops in the lining of the lungs, abdomen or heart. It is linked to inhalation of asbestos commonly used in ship building and the insulation industry. It has no known cure and has a very poor prognosis.

    • This question is part of the following fields:

      • Neoplasia
      • Pathology
      13
      Seconds
  • Question 16 - A patients sciatic nerve has been severed following a stab injury. What would...

    Incorrect

    • A patients sciatic nerve has been severed following a stab injury. What would be affected?

      Your Answer: The muscles in the anterior compartment of the leg would still be functional

      Correct Answer: There would still be cutaneous sensation over the anteromedial surface of the thigh

      Explanation:

      The sciatic nerve supplies nearly all of the sensation of the skin of the leg and the muscles of the back of the thigh, leg and foot. A transection of the sciatic nerve at its exit from the pelvis will affect all the above-mentioned functions except cutaneous sensation over the anteromedial surface of the thigh, which comes from the femoral nerve.

    • This question is part of the following fields:

      • Anatomy
      • Lower Limb
      85.7
      Seconds
  • Question 17 - Muscles and tendons in the planter region of the foot mainly take blood...

    Correct

    • Muscles and tendons in the planter region of the foot mainly take blood supply from:

      Your Answer: Posterior tibial artery

      Explanation:

      The posterior tibial artery is the main source of blood supply to the posterior compartment of the leg.

    • This question is part of the following fields:

      • Anatomy
      • Lower Limb
      41.4
      Seconds
  • Question 18 - A teenager presents with pain and swelling in a limb which increases after...

    Incorrect

    • A teenager presents with pain and swelling in a limb which increases after activity. X-rays reveal an expansible, eccentric, lytic lesion in the metaphysis distally in the affected bone surrounded by new bone. What is the most likely diagnosis?

      Your Answer: Osteosarcoma

      Correct Answer: Aneurysmal bone cyst

      Explanation:

      Aneurysmal bone cysts tend to develop in patients younger than 20 years old. They usually occur in the metaphyseal region of long bones, and are cystic lesions composed of numerous blood filled channels that grow slowly. In X-rays, they show up as circumscribed lesions, sometimes surrounded by new bone.

    • This question is part of the following fields:

      • Orthopaedics
      • Pathology
      77.3
      Seconds
  • Question 19 - A 20 year old is brought to the A&E after he fell from...

    Correct

    • A 20 year old is brought to the A&E after he fell from a moving cart. The boy has sustained blunt abdominal injury, and the there is a possibility of internal bleeding as the boy is in shock. An urgent exploratory laparotomy is done in the A&E theatre. On opening the peritoneal cavity, the operating surgeon notices a torn gastrosplenic ligament with a large clot around the spleen. Which artery is most likely to have been injured in this case?

      Your Answer: Short gastric

      Explanation:

      The short gastric arteries branch from the splenic artery near the splenic hilum to travel back in the gastrosplenic ligament to supply the fundus of the stomach. Therefore, these may be injured in this case.

      The splenic artery courses deep to the stomach to reach the hilum of the spleen. It doesn’t travel in the gastrosplenic ligament although it does give off branches that do.

      The middle colic artery is a branch of the superior mesenteric artery that supplies the transverse colon.

      Gastroepiploic artery is the largest branch of the splenic artery that courses between the layers of the greater omentum to anastomose with the right gastroepiploic.

      Left gastric artery, a branch of the coeliac trunk. It supplies the left half of the lesser curvature.

    • This question is part of the following fields:

      • Abdomen
      • Anatomy
      50.2
      Seconds
  • Question 20 - Where is the foramen ovale located? ...

    Correct

    • Where is the foramen ovale located?

      Your Answer: Sphenoid

      Explanation:

      The foramen ovale is an oval shaped opening in the middle cranial fossa located at the posterior base of the greater wing of the sphenoid bone, lateral to the lingula. It transmits the mandibular division of the trigeminal nerve (CN Vc), accessory meningeal artery, emissary veins between the cavernous sinuses and pterygoid plexus, otic ganglion, and occasionally the nervus spinosus and lesser petrosal nerve.

    • This question is part of the following fields:

      • Anatomy
      • Head & Neck
      34.2
      Seconds
  • Question 21 - A 76 year old man who presented with lower back pain is diagnosed...

    Correct

    • A 76 year old man who presented with lower back pain is diagnosed with prostatic carcinoma that has metastasized to his lumber spine. Which of the following markers is characteristically elevated?

      Your Answer: PSA

      Explanation:

      Spread of prostatic carcinoma is common to the lumbar spine and pelvis. This results in osteoblastic metastases that will present as lower back pain with increased alkaline phosphatase, prostatic acid phosphates and PSA. PSA is more specific and a PSA > 10 ng/ml for any age is worrisome.

    • This question is part of the following fields:

      • Neoplasia; Urology
      • Pathology
      12.4
      Seconds
  • Question 22 - An abdominal aortogram shows occlusion of the inferior mesenteric artery. Which of the...

    Incorrect

    • An abdominal aortogram shows occlusion of the inferior mesenteric artery. Which of the following segments of bowel is most likely to have preserved arterial supply?

      Your Answer: Descending colon

      Correct Answer: Caecum

      Explanation:

      The inferior mesenteric artery supplies blood to the end of the transverse colon and all distal structures in the gastrointestinal tract i.e. splenic flexure, descending colon, sigmoid colon and rectum would all be deprived of blood if it were occluded. The caecum receives blood from the superior mesenteric artery so it would not be affected.

    • This question is part of the following fields:

      • Abdomen
      • Anatomy
      152.1
      Seconds
  • Question 23 - A 55-year old lady underwent a major surgery for repair of an aortic...

    Incorrect

    • A 55-year old lady underwent a major surgery for repair of an aortic aneurysm. Her blood pressure was low throughout the intra-operative and the post-operative period, along with increasing serum creatinine and urea. Microscopic examination of her urine showed multiple granular and hyaline casts. What is the likely condition the patient is suffering from?

      Your Answer: Renal artery stenosis

      Correct Answer: Acute tubular necrosis

      Explanation:

      The most common predisposing factor leading to acute tubular necrosis is ischemia, typically seen in hospitalized patients with low blood pressure.

    • This question is part of the following fields:

      • Pathology
      • Renal
      133.6
      Seconds
  • Question 24 - If a catheter is placed in the main pulmonary artery of a healthy...

    Incorrect

    • If a catheter is placed in the main pulmonary artery of a healthy 30-year-old woman, which of the following will be its mean pulmonary arterial pressure?

      Your Answer: 110 mmHg

      Correct Answer: 15 mmHg

      Explanation:

      The pulmonary artery pressure (PA pressure) is a measure of the blood pressure found in the main pulmonary artery. The hydrostatic pressure of the pulmonary circulation refers to the actual pressure inside pulmonary vessels relative to atmospheric pressure. Hydrostatic (blood pressure) in the pulmonary vascular bed is low compared with that of similar systemic vessels. The mean pulmonary arterial pressure is about 15 mmHg (ranging from about 13 to 19 mmHg) and is much lower than the average systemic arterial pressure of 90 mmHg.

    • This question is part of the following fields:

      • Physiology
      • Respiratory
      67.5
      Seconds
  • Question 25 - During work up for a 29 year-old lady who complained of chest pain,...

    Incorrect

    • During work up for a 29 year-old lady who complained of chest pain, a computed tomography showed a large mass in the posterior mediastinum. Which among the following structures could be involved?

      Your Answer: Aortic arch

      Correct Answer: Lymph nodes

      Explanation:

      Boundaries of the posterior mediastinum include:

      Superior: a plane through the sternal angle and T4/5

      Inferior: the diaphragm

      Anterior: the middle mediastinal structures

      Posterior the spinal cord.

      Structures in the posterior mediastinum include the descending thoracic aorta, the azygos system, oesophagus, thoracic duct and lymph nodes. The great vessels and structures at the root of the lung are part of the middle mediastinum. In this case, the lymph nodes is the correct answer.

    • This question is part of the following fields:

      • Anatomy
      • Thorax
      215.9
      Seconds
  • Question 26 - The circle of Willis is one of the cerebrovascular safeguards comprised of the...

    Correct

    • The circle of Willis is one of the cerebrovascular safeguards comprised of the left and the right posterior communicating artery. Which of the following arteries in the brain is connected to the posterior cerebral artery by these posterior communicating arteries?

      Your Answer: Internal carotid artery

      Explanation:

      The Circle of Willis is an anastomosis of cerebral arteries that are located at the base of the brain. The Circle of Willis is one of the important safeguards that ensure back up of blood supply to parts of the brain in case of any cerebrovascular accident. The Circle of Willis is made up of an anterior portion of arteries including; the anterior cerebral arteries. The anterior cerebral arteries are connected to the posterior portion of the circle of Willis by the anterior communicating artery. The posterior portion is made up of the posterior cerebral artery which branch off from the basilar artery. The posterior cerebral artery are connected to the anterior portion of the circle of Willis by the posterior communicating artery. The posterior communicating artery connects the posterior cerebral artery to the internal carotid artery. The circle of Willis receives blood supply from the left and right internal carotid arteries that continues as the middle cerebral artery and posteriorly from the two vertebral arteries that join to form the basilar artery.

    • This question is part of the following fields:

      • Anatomy
      • Head & Neck
      63.9
      Seconds
  • Question 27 - Carbon dioxide is principally transported in the blood in which form? ...

    Incorrect

    • Carbon dioxide is principally transported in the blood in which form?

      Your Answer: Carboxyhaemoglobin

      Correct Answer: Bicarbonate

      Explanation:

      Carbon dioxide is transported in the blood in various forms:

      – Bicarbonate (80–90%)

      – Carbamino compounds (5–10%)

      – Physically dissolved in solution (5%).

      Carbon dioxide is carried on the haemoglobin molecule as carbamino-haemoglobin; carboxyhaemoglobin is the combination of haemoglobin with carbon monoxide.

    • This question is part of the following fields:

      • Physiology
      • Respiratory; Cardiovascular
      39
      Seconds
  • Question 28 - Normally, the O2 transfer in the lungs from alveolar to capillary is perfusion-limited....

    Correct

    • Normally, the O2 transfer in the lungs from alveolar to capillary is perfusion-limited. In which of the following situations does it become a diffusion-limited process?

      Your Answer: Pulmonary oedema

      Explanation:

      Normally, the transfer of oxygen from air spaces to blood takes place across the alveolar-capillary membrane by simple diffusion and depends entirely on the amount of blood flow (perfusion-limited process). Diseases that affect this diffusion will transform the normal process to a diffusion limited process. Thus, the diseases which cause a thickened barrier (such as pulmonary oedema due to increased extravascular lung water or asbestosis) will limit the diffusion of oxygen. Chronic obstructive lung diseases will have little effect on diffusion. Inhaling hyperbaric gas mixtures might overcome the diffusion limitation in patients with mild asbestosis or interstitial oedema, by increasing the driving force. Strenuous (not mild) exercise might also favour diffusion limitation and decrease passage time. Increasing the rate of ventilation will not have this affect but will only maintain a high oxygen gradient from air to blood.

    • This question is part of the following fields:

      • Physiology
      • Respiratory
      87.7
      Seconds
  • Question 29 - The following joint has an anastomotic circulation that is provided by branches of...

    Incorrect

    • The following joint has an anastomotic circulation that is provided by branches of the brachial artery:

      Your Answer: Head of the humerus

      Correct Answer: Elbow joint

      Explanation:

      The arterial anastomoses of the elbow joint is contributed by branches of the brachial artery and the Profunda brachii artery. The brachial artery gives off the superior ulnar collateral artery and the inferior collateral artery. On the other hand, the Profunda brachii gives off the radial and medial recurrent arteries.

    • This question is part of the following fields:

      • Anatomy
      • Upper Limb
      40.2
      Seconds
  • Question 30 - Which is a feature of the action of insulin? ...

    Correct

    • Which is a feature of the action of insulin?

      Your Answer: Promotes protein synthesis

      Explanation:

      Insulin is produced by the beta-cells of the islets of Langerhans in the pancreas. Its actions include:

      – promoting uptake of glucose into cells

      – glycogen synthesis (glycogenesis)

      – protein synthesis

      – stimulation of lipogenesis (fat formation).

      – driving potassium into cells – used to treat hyperkaelamia.

      Parathyroid hormone and activated vitamin D are the principal hormones involved in calcium/phosphate metabolism, rather than insulin.

    • This question is part of the following fields:

      • Endocrine
      • Physiology
      87.9
      Seconds
  • Question 31 - C5a (a complement component) is a potent? ...

    Correct

    • C5a (a complement component) is a potent?

      Your Answer: Anaphylotoxin

      Explanation:

      C5a is a strong chemoattractant as well as an anaphylotoxin and is involved in the recruitment of inflammatory cells such as neutrophils, eosinophils, monocytes, and T lymphocytes. It is also involved in activation of phagocytic cells, release of granule-based enzymes and generation of oxidants. All of which contribute to innate immune functions.

    • This question is part of the following fields:

      • General
      • Physiology
      23.3
      Seconds
  • Question 32 - From which of the following cells is heparin produced? ...

    Correct

    • From which of the following cells is heparin produced?

      Your Answer: Mast cells

      Explanation:

      Heparin is a natural highly-sulphated glycosaminoglycan that has anticoagulant functions. It is produced by the body basophils and mast cells.

    • This question is part of the following fields:

      • Haematology
      • Pathology
      5.7
      Seconds
  • Question 33 - A patient sustained an injury to the facial nerve after it emerges from...

    Correct

    • A patient sustained an injury to the facial nerve after it emerges from the stylomastoid foramen. What is the clinical impact of this injury?

      Your Answer: Facial expression

      Explanation:

      The facial nerve is the seventh of the twelve paired cranial nerves. It emerges from the brainstem between the pons and the medulla. It controls the muscles of facial expression and supplies taste fibres to the anterior two-thirds of the tongue. It also supplies preganglionic parasympathetic fibres to several head and neck ganglia. Its branches and distribution are as follows:

      Inside the facial canal (proximal to the stylomastoid foramen):

      – Greater petrosal nerve – provides parasympathetic innervation to the lacrimal gland, as well as special taste sensory fibres to the palate via the nerve of pterygoid canal

      – Nerve to stapedius – provides motor innervation for the stapedius muscle in the middle ear

      – Chord tympani – provides parasympathetic innervation to the submandibular and sublingual glands and special sensory taste fibres for the anterior two-thirds of the tongue

      Outside the skull (distal to the stylomastoid foramen):

      – Posterior auricular nerve – controls the movements of some of the scalp muscles around the ear

      – Five major facial branches (in the parotid gland), from top to bottom: temporal branch, zygomatic branch, buccal branch, marginal mandibular branch and cervical branch. From the description given above it is obvious that injury to the facial nerve distal to the stylomastoid foramen will affect facial expression.

    • This question is part of the following fields:

      • Anatomy
      • Head & Neck
      152.6
      Seconds
  • Question 34 - Injury to the supraspinatus muscle will affect: ...

    Incorrect

    • Injury to the supraspinatus muscle will affect:

      Your Answer: Lateral rotation of the humerus

      Correct Answer: Initiation of abduction of the humerus

      Explanation:

      This muscle arises from the medial two-thirds of the supraspinatus fossa and from the supraspinatus fascia. It is inserted into the highest impression on the greater tubercle of the humerus after passing over the upper part of the shoulder joint. It works with the deltoid to raise the arm from the side of the trunk and initiate abduction. It also assists in fixation of the head of the humerus in the glenoid cavity.

    • This question is part of the following fields:

      • Anatomy
      • Upper Limb
      30.9
      Seconds
  • Question 35 - Which tumour marker is associated with medullary carcinoma of thyroid? ...

    Incorrect

    • Which tumour marker is associated with medullary carcinoma of thyroid?

      Your Answer: CA-125

      Correct Answer: Calcitonin

      Explanation:

      Medullary carcinoma of thyroid accounts for 3% of thyroid cancers. It arises from the parafollicular cells (C cells) of the thyroid gland that produce calcitonin. It is often familial and caused by mutation of ret proto-oncogene, but can occasionally be sporadic. The familial cases can also occur as part of MEN syndromes IIA and IIB. The high calcitonin leads to down-regulation of the receptors, which does not affect the calcium levels significantly. Medullary carcinoma of thyroid shows characteristic amyloid deposits that stain positively with Congo red. The initial presentation consists of an asymptomatic thyroid nodule. Many cases are diagnosed due to routine screening of relatives of patients with MEN IIA and IIB. Medullary carcinoma can also cause ectopic production of other hormones/peptides such as adrenocorticotrophic hormone, vasoactive intestinal polypeptide, kallikreins and serotonin.

      Metastasis from medullary carcinoma spread via the lymphatics to cervical and mediastinal nodes, and can also affect the liver, lungs and bone. Diagnosis is by raised serum calcitonin levels. A provocative test with calcium (15 mg/kg intravenously over 4 hours) also aids in diagnosis by leading to excessive secretion of calcitonin. X-ray might also show dense, conglomerate calcification.

      CA-125 is frequently elevated in ovarian carcinomas. CA 15-3 is often associated with breast carcinomas. Alpha-fetoprotein is seen raised in hepatomas and gonadal tumours. Elevated HCG is associated with normal pregnancies, gonadal tumours, and choriocarcinomas. Thyroglobulin is used for surveillance in papillary carcinoma of thyroid. CA 19-9 is used in the management of pancreatic cancer.

    • This question is part of the following fields:

      • Endocrine
      • Pathology
      72.2
      Seconds
  • Question 36 - A cerebellar tremor can be differentiated from a Parkinsonian tremor in that: ...

    Incorrect

    • A cerebellar tremor can be differentiated from a Parkinsonian tremor in that:

      Your Answer: It is decreased during activity

      Correct Answer: It only occurs during voluntary movements

      Explanation:

      Cerebellar disease leads to intention tremors, which is absent at rest and appears at the onset of voluntary movements. In comparison, Parkinson’s tremor is present at rest. Frequency of tremor is a less reliable means to differentiate between the two as the oscillation amplitude of the tremor is not constant throughout a voluntary action.

    • This question is part of the following fields:

      • Neurology
      • Physiology
      330.3
      Seconds
  • Question 37 - A 10-year-old boy was sent for an x-ray of the leg because he...

    Correct

    • A 10-year-old boy was sent for an x-ray of the leg because he was complaining of pain and swelling. The x-ray showed the classic sign of Codman's triangle. What is the most likely diagnosis of this patient?

      Your Answer: Osteosarcoma

      Explanation:

      Codman’s triangle is the triangular area of new subperiosteal bone that is created when a lesion, often a tumour, raises the periosteum away from the bone. The main causes for this sign are osteosarcoma, Ewing’s sarcoma, eumycetoma, and a subperiosteal abscess.

    • This question is part of the following fields:

      • Neoplasia
      • Pathology
      54.7
      Seconds
  • Question 38 - To reach the oral vestibule, the parotid duct must pierce this muscle: ...

    Correct

    • To reach the oral vestibule, the parotid duct must pierce this muscle:

      Your Answer: Buccinator muscle

      Explanation:

      The parotid duct or Stensen duct is a duct and the route that saliva takes from the major salivary gland, the parotid gland into the mouth. The parotid duct is formed when several interlobular ducts—the largest ducts inside the parotid gland join. It emerges from the gland and runs forward along the lateral side of the masseter muscle. In this course, the duct is surrounded by the buccal fat pad. It takes a steep turn at the border of the masseter and passes through the buccinator muscle, opening into the vestibule of the mouth, between the cheek and the gums, at the parotid papilla, which lies across the second superior molar tooth.

    • This question is part of the following fields:

      • Anatomy
      • Head & Neck
      11
      Seconds
  • Question 39 - A mechanic sustained a deep laceration to his right cubital fossa which resulted...

    Correct

    • A mechanic sustained a deep laceration to his right cubital fossa which resulted in him unable to move the proximal radioulnar joint of his right arm. Which muscles was affected?

      Your Answer: Pronator teres

      Explanation:

      The correct answer is the pronator teres muscle. This muscle arises from 2 heads of origin: the humerus and ulnar. Between the 2 heads is the site of entrance of median nerve to the forearm. This muscle acts on the proximal radio-ulnar joint to rotate the radius on the ulna, otherwise known as pronation. It also assists in forearm flexion if the radius is fixed.

    • This question is part of the following fields:

      • Anatomy
      • Upper Limb
      132.3
      Seconds
  • Question 40 - After a severe asthma attack, a 26-year-old woman is left in a markedly...

    Correct

    • After a severe asthma attack, a 26-year-old woman is left in a markedly hypoxic state. In which of the following organs are the arterial beds most likely to be vasoconstricted due to the hypoxia?

      Your Answer: Lungs

      Explanation:

      Hypoxic pulmonary vasoconstriction is a local response to hypoxia resulting primarily from constriction of small muscular pulmonary arteries in response to reduced alveolar oxygen tension. This unique response of pulmonary arterioles results in a local adjustment of perfusion to ventilation. This means that if a bronchiole is obstructed, the lack of oxygen causes contraction of the pulmonary vascular smooth muscle in the corresponding area, shunting blood away from the hypoxic region to better-ventilated regions. The purpose of hypoxic pulmonary vasoconstriction is to distribute blood flow regionally to increase the overall efficiency of gas exchange between air and blood.

    • This question is part of the following fields:

      • Physiology
      • Respiratory
      37
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Anatomy (10/17) 59%
Thorax (2/3) 67%
Fluids & Electrolytes (1/3) 33%
Pathology (7/14) 50%
Physiology (4/9) 44%
Pharmacology (2/2) 100%
Microbiology (0/1) 0%
Upper Limb (1/4) 25%
Orthopaedics (0/2) 0%
Urology (0/1) 0%
Neurology (0/2) 0%
Lower Limb (1/3) 33%
Abdomen (2/3) 67%
Neoplasia (2/2) 100%
Head & Neck (4/4) 100%
Neoplasia; Urology (1/1) 100%
Renal (0/1) 0%
Respiratory (2/3) 67%
Respiratory; Cardiovascular (0/1) 0%
Endocrine (1/2) 50%
General (1/1) 100%
Haematology (1/1) 100%
Passmed