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  • Question 1 - What is the primary function of collagen in wound healing? ...

    Correct

    • What is the primary function of collagen in wound healing?

      Your Answer: Strength and support

      Explanation:

      Key elements of the maturation stage include collagen cross-linking, collagen remodelling, wound contraction, and repigmentation. The tensile strength of the wound is directly proportional to the amount of collagen present. Numerous types of collagen have been identified; types I and III predominate in the skin and aponeurotic layers. Initially, a triple helix (tropocollagen) is formed by three protein chains; two are identical alpha-1 protein chains, and the third is an alpha-2 protein.

    • This question is part of the following fields:

      • Pathology
      • Wound Healing
      113.2
      Seconds
  • Question 2 - A 56-year-old male with a 10-year history of Diabetes Mellitus and Hypertension was...

    Correct

    • A 56-year-old male with a 10-year history of Diabetes Mellitus and Hypertension was rushed to the Emergency Department due to sudden onset crushing chest pain. ECG showed an ST-elevation myocardial infarct in the left anterior descending artery territory. The patient's condition was stabilised and managed with angioplasty, but he sustained significant myocardial damage.

      Which one of the following statements best agrees with the myocardial healing process?

      Your Answer: The left ventricle will likely hypertrophy first to maintain cardiac output

      Explanation:

      Following a myocardial infarction scar tissue formation will take place at the site of the damaged muscle. This places increased load on the rest of the myocardium causing it to hypertrophy. The left ventricle will hypertrophy first as it is pumping blood against a greater afterload as compared to the right ventricle.

      There are three types of cells in the body with regards to the cell cycle: 1. permanent
      2. labile
      3. stable cells

      Permanent cells do not re-enter the cell cycle and remain in G0. If there is a pool of stem cells the stem cells will enter the cell cycle to form more cells. Myocardial cells are a type of permanent cell and there is no pool of stem cells in the heart muscle. The anterior wall will not hypertrophy as it is formed by the right atrium and ventricle and both of these hypertrophy after the left ventricle.

    • This question is part of the following fields:

      • General Pathology
      • Pathology
      89
      Seconds
  • Question 3 - The least likely feature of anaemia is: ...

    Correct

    • The least likely feature of anaemia is:

      Your Answer: Narrow pulse pressure

      Explanation:

      Non-specific signs of anaemia include:
      1. pallor of mucous membranes or nail beds (if Hb < 90 g/L),
      2. tachycardia
      3. bounding pulse
      4. wide pulse pressure
      5. flow murmurs
      6. cardiomegaly
      7. signs of congestive cardiac failure (in severe cases)

    • This question is part of the following fields:

      • Haematology
      • Pathology
      25.6
      Seconds
  • Question 4 - Which of the following statements about neutrophils is TRUE: ...

    Correct

    • Which of the following statements about neutrophils is TRUE:

      Your Answer: Neutrophils are typically the first immune cell to arrive to a site of injury.

      Explanation:

      Neutrophils are the most numerous peripheral blood leukocytes, accounting for 50-70 percent of all circulating white cells. Neutrophils have a compact nucleus with two to five lobes and a pale cytoplasm with an irregular shape containing numerous fine pink-blue or grey-blue granules. The granules are classified as primary, which emerges during the promyelocyte stage, and secondary, which develop at the myelocyte stage and predominate in the mature nucleus.

      The lifespan of neutrophils in the blood is only 6 – 10 hours. In response to tissue damage, cytokines and complement proteins, neutrophils migrate from the bloodstream to the site of insult within minutes, where they destroy pathogens by phagocytosis.

    • This question is part of the following fields:

      • Immune Responses
      • Pathology
      20.2
      Seconds
  • Question 5 - Given a patient with dislocation of the patella, which muscle is the most...

    Incorrect

    • Given a patient with dislocation of the patella, which muscle is the most important to address during rehabilitation to prevent recurrent dislocation?

      Your Answer: Rectus femoris

      Correct Answer: Vastus medialis

      Explanation:

      Patellar dislocation is a disabling musculoskeletal disorder which predominantly affects younger people who are engaged in multidirectional physically active pursuits. Conservative (non-operative) treatment is the treatment of choice for FTPD (first time patellar dislocation). Quadriceps strengthening exercises are considered one of the principal management aims for people following FTPD. A United Kingdom (UK) survey of physiotherapy practice has shown that quadriceps strengthening and specific-vastus medialis obliquus (VMO) or distal vastus medialis (VM) muscle strengthening or recruitment exercises were two of the most frequently used interventions for this population. Specific VM exercises are favoured in some quarters based on the assumption that the VM has an important role in preventing excessive lateral patellar translation.

    • This question is part of the following fields:

      • Anatomy
      • Lower Limb
      10.9
      Seconds
  • Question 6 - Which of the following is NOT mainly characterised by intravascular haemolysis: ...

    Incorrect

    • Which of the following is NOT mainly characterised by intravascular haemolysis:

      Your Answer: Paroxysmal nocturnal haemoglobinuria

      Correct Answer: Beta-Thalassaemia

      Explanation:

      Causes of intravascular haemolysis:
      Haemolytic transfusion reactions
      G6PD deficiency
      Red cell fragmentation syndromes
      Some severe autoimmune haemolytic anaemias
      Some drug-and infection-induced haemolytic anaemias
      Paroxysmal nocturnal haemoglobinuria

    • This question is part of the following fields:

      • Haematology
      • Pathology
      27.9
      Seconds
  • Question 7 - You're in resus with a 69-year-old woman who is very sick. You decide...

    Incorrect

    • You're in resus with a 69-year-old woman who is very sick. You decide to contact the intensive care outreach team because she appears to be in septic shock. They decide to start a dobutamine infusion as soon as they arrive.

      Which of the following statements about dobutamine is correct?

      Your Answer: It only acts at beta-adrenergic receptors

      Correct Answer: It may be infused via a peripheral line

      Explanation:

      Dobutamine is a synthetic isoprenaline derivative that is used to provide inotropic support to patients with low cardiac output caused by septic shock, myocardial infarction, or other cardiac conditions.

      Dobutamine is a sympathomimetic drug that stimulates beta-1 adrenergic receptors in the heart to produce its primary effect. As a result, it has inotropic properties that increase cardiac contractility and output. It also has a small amount of alpha1- and beta-2-adrenergic activity.

      It is infused intravenously after being diluted to a volume of at least 50 ml in a suitable crystalloid solution. The dose is titrated to response and ranges from 0.5 to 40 g/kg/min. Extravasation-induced skin necrosis is uncommon, and dobutamine can be administered through a peripheral line.

      At doses below 10 g/kg/min, side effects are rare, but at higher doses, they can include:
      Nausea and vomiting
      Tachycardia
      Dysrhythmias
      Angina
      Hypertension
      Headache

    • This question is part of the following fields:

      • Cardiovascular Pharmacology
      • Pharmacology
      88.2
      Seconds
  • Question 8 - An outbreak of acute pneumonia occurs in military recruits living in one barrack...

    Correct

    • An outbreak of acute pneumonia occurs in military recruits living in one barrack and only in those persons located near the air conditioner. Epidemiologic surveillance results in isolation of the causal organism from the patients and from the drip pans of the air conditioner. The organism is weakly Gram-negative. The most likely organism is:

      Your Answer: Legionella pneumophila

      Explanation:

      Legionella pneumophilais a Gram negative bacterium that is found in natural water supplies and in the soil, transmitted predominantly via inhalation of aerosols generated from contaminated water (direct person-to-person spread of infected patients does not occur). It is the cause of Legionnaires’ disease. Outbreaks of Legionnaires’ disease have been linked to poorly maintained air conditioning systems, whirlpool spas and hot tubs.

      The clinical features of the pneumonic form of Legionnaires’ disease include:
      Mild flu-like prodrome for 1-3 days
      Cough (usually non-productive and occurs in approximately 90%)
      Pleuritic chest pain
      Haemoptysis
      Headache
      Nausea, vomiting and diarrhoea
      Anorexia
      Legionella pneumophilainfections can be successfully treated with macrolide antibiotics, such as erythromycin, or quinolones, such as ciprofloxacin. Tetracyclines, such as doxycycline, can also be used.
      The syndrome of inappropriate antidiuretic hormone secretion (SIADH) can occur with Legionnaires’ disease and will result in hyponatraemia as is seen in this case.
      Legionella pneumophilainfections are resistant to amoxicillin but can be successfully treated with macrolide antibiotics, such as erythromycin, or quinolones, such as ciprofloxacin. Tetracyclines, such as doxycycline, can also be used. The majority of cases of Legionnaires’ disease are caused by Legionella pneumophila, however many other species of Legionella have been identified.
      Legionella longbeachae is another less commonly encountered species that has also been implicated in outbreaks. It is predominantly found in soil and potting compost, and has caused outbreaks of Pontiac fever, the non-respiratory and less severe variant of Legionnaires’ disease.

    • This question is part of the following fields:

      • Microbiology
      • Pathogens
      15.7
      Seconds
  • Question 9 - A 60-year-old man presents with marked breathlessness. He has with a history of...

    Incorrect

    • A 60-year-old man presents with marked breathlessness. He has with a history of ischaemic heart disease. On examination, there is coarse bibasal crackles, marked peripheral oedema and chest X-ray taken is consistent with severe pulmonary oedema. RR is 28 per minute.

      Which receptor is responsible for detecting pulmonary oedema and the subsequent increase in respiratory rate?

      Your Answer: Central chemoreceptors

      Correct Answer: Juxtacapillary receptors

      Explanation:

      Pulmonary oedema causes stimulation of the Juxtacapillary receptors (J receptors) leading to a reflex increase in breathing rate. These receptors are also thought to be involved in the sensation of dyspnoea. The J receptors are sensory cells and are located within the alveolar walls in juxtaposition to the pulmonary capillaries.

      Aortic baroreceptor are involved in detecting blood pressure

      Central chemoreceptors detect changes in CO2 and hydrogen ion within the brain

      Atrial volume receptors regulate plasma volume

    • This question is part of the following fields:

      • Physiology
      • Respiratory Physiology
      61.9
      Seconds
  • Question 10 - Caseous necrosis is typically seen in which of the following: ...

    Correct

    • Caseous necrosis is typically seen in which of the following:

      Your Answer: Tuberculosis

      Explanation:

      Caseous necrosis is most commonly seen in tuberculosis. Histologically, the complete loss of normal tissue architecture is replaced by amorphous, granular and eosinophilic tissue with a variable amount of fat and an appearance reminiscent of cottage cheese.

    • This question is part of the following fields:

      • Inflammatory Responses
      • Pathology
      17.6
      Seconds
  • Question 11 - A 20-year-old male patient lives in a travelling community and has never...

    Incorrect

    • A 20-year-old male patient lives in a travelling community and has never received any vaccinations. He presents to you with fever.

      Which of these statements concerning indications and contraindications for vaccination is TRUE?

      Your Answer: Premature infants should not be vaccinated according to the usual immunisation schedule

      Correct Answer: Inactivated vaccines are safe in pregnancy

      Explanation:

      All vaccines are contraindicated in individuals with: A confirmed anaphylactic reaction to a previous dose of the vaccine or a vaccine containing the same antigens.
      A confirmed anaphylactic reaction to a component in the vaccine e.g. neomycin

      There is no evidence that vaccinating pregnant women with inactivated vaccine or toxoids harms the woman or foetus.

      The current protocol is that a child with history of egg allergy can be safely vaccinated with Fluenz tetra. However, if they had a previous severe anaphylaxis to egg requiring intensive care, then Flenz tetra is contraindicated.

      BCG, yellow fever or oral typhoid vaccinations are not safe in HIV positive patients.

      The normal times recommended for immunization of full-term babies should also be applied to premature infants and correction for gestational age should not be implemented.

      Concurrent antibiotic therapy is not a contraindication to vaccination.

    • This question is part of the following fields:

      • Microbiology
      • Principles Of Microbiology
      58.5
      Seconds
  • Question 12 - A 42-year-old man presented to the emergency room after an incident of slipping...

    Incorrect

    • A 42-year-old man presented to the emergency room after an incident of slipping and falling onto his back and left hip. Upon physical examination, it was noted that he has pain on hip adduction, but normal hip flexion.

      Which of the following muscles was most likely injured in this case?

      Your Answer: Psoas major

      Correct Answer: Pectineus

      Explanation:

      The hip adductors are a group of five muscles located in the medial compartment of the thigh. These muscles are the adductor longus, adductor brevis, adductor magnus, gracilis, and pectineus.

      The hip flexors consist of 5 key muscles that contribute to hip flexion: iliacus, psoas, pectineus, rectus femoris, and sartorius.

    • This question is part of the following fields:

      • Anatomy
      • Lower Limb
      34.6
      Seconds
  • Question 13 - Which of the following statements concerning the facial nerve is INCORRECT? ...

    Incorrect

    • Which of the following statements concerning the facial nerve is INCORRECT?

      Your Answer: The facial nerve supplies taste to the anterior two-thirds of the tongue.

      Correct Answer: Forehead sparing in facial nerve palsy is indicative of a lower motor neuron lesion.

      Explanation:

      In facial nerve palsy, LMN damage will involve the forehead and there will be an inability to close the eyes due to paralysis of the orbicularis oculi or raise the eyebrows due to paralysis of the occipitofrontalis muscle.
      UMN damage causes sparing of the forehead as the occipitofrontalis and orbicularis oculi muscles have bilateral cortical representation.

    • This question is part of the following fields:

      • Anatomy
      • Cranial Nerve Lesions
      31.7
      Seconds
  • Question 14 - If the ejection fraction increases, there will be a decrease in: ...

    Incorrect

    • If the ejection fraction increases, there will be a decrease in:

      Your Answer: Cardiac output

      Correct Answer: End-systolic volume

      Explanation:

      An increase in ejection fraction means that a higher fraction of the end-diastolic volume is ejected in the stroke volume (e.g. because of the administration of a positive inotropic agent). When this situation occurs, the volume remaining in the ventricle after systole, the end-systolic volume, will be reduced. Cardiac output, stroke volume, and mean arterial pressure will be increased.

    • This question is part of the following fields:

      • Cardiovascular
      • Physiology
      21.5
      Seconds
  • Question 15 - A 10-year-old girl that appears systemically well presents with a honey-crusted scab close...

    Correct

    • A 10-year-old girl that appears systemically well presents with a honey-crusted scab close to the corner of her mouth and states that the area is slightly itchy but not painful. The diagnosis given was impetigo.

      What is most likely the mode of transmission of the causative agent of the said diagnosis?

      Your Answer: Direct contact

      Explanation:

      Impetigo is a common pyoderma that is most often seen in children. Historically, most cases were caused by group A streptococci (GAS; Streptococcus pyogenes), although S. aureus has become the predominant pathogen over the last 15 years.

      A bullous form of impetigo accounts for approximately 10% of cases. It is caused by strains of S. aureus that produce exfoliative toxins leading to the formation of bullae, which quickly rupture and form a transparent, light brown crust.

      Impetigo is spread mainly by person-to-person contact; it is rapidly spread through direct transmission. The diagnosis of impetigo can be made from a Gram stain and culture of the vesicular contents.

    • This question is part of the following fields:

      • Microbiology
      • Principles Of Microbiology
      24.2
      Seconds
  • Question 16 - Regarding the glomerular filtration barrier, which of the following statements is CORRECT: ...

    Correct

    • Regarding the glomerular filtration barrier, which of the following statements is CORRECT:

      Your Answer: The main factor determining whether a substance is filtered or not is molecular weight.

      Explanation:

      Molecular weight is the main factor in determining whether a substance is filtered or not – molecules < 7 kDa in molecular weight are filtered freely e.g. glucose, amino acids, urea, ions but larger molecules are increasingly restricted up to 70 kDa, above which filtration is insignificant. Negatively charged molecules are further restricted, as they are repelled by negative charges, particularly in the basement membrane. Albumin has a molecular weight of 69 kDa and is negatively charged, thus only very small amounts are filtered (and all of the filtered albumin is reabsorbed in the proximal tubule), whereas small molecules such as ions, glucose, amino acids and urea pass the filter without hindrance. This means that ultrafiltrate is virtually protein free, but otherwise has an identical composition of that of plasma. The epithelial lining of the Bowman's capsule consists of a single layer of cells called podocytes. The glomerular capillary endothelium is perforated by pores (fenestrations) which allow plasma components with a molecular weight of < 70 kDa to pass freely.

    • This question is part of the following fields:

      • Physiology
      • Renal
      44
      Seconds
  • Question 17 - Regarding inhaled corticosteroids, which of the following statements is INCORRECT: ...

    Correct

    • Regarding inhaled corticosteroids, which of the following statements is INCORRECT:

      Your Answer: Lower doses of inhaled corticosteroids may be required in smokers.

      Explanation:

      Current and previous smoking reduces the effectiveness of inhaled corticosteroids and higher doses may be necessary.

    • This question is part of the following fields:

      • Pharmacology
      • Respiratory
      61.4
      Seconds
  • Question 18 - You examine a 34-year-old lady with symptoms that are consistent with acute sinusitis. You're...

    Incorrect

    • You examine a 34-year-old lady with symptoms that are consistent with acute sinusitis. You're thinking about giving her doxycycline for treatment.

      What is doxycycline's mechanism of action?

      Your Answer: Inhibition of nucleic acid synthesis

      Correct Answer: Inhibition of protein synthesis

      Explanation:

      Doxycycline and other tetracycline antibiotics attach to the 30S subunit of the bacterial ribosome, preventing aminoacyl-tRNA binding and so protein synthesis beginning.

    • This question is part of the following fields:

      • Infections
      • Pharmacology
      36.9
      Seconds
  • Question 19 - A 29-year-old man has been complaining about his recent headaches. Detailed history was...

    Incorrect

    • A 29-year-old man has been complaining about his recent headaches. Detailed history was taken and a neurological examination was performed.

      Which of the following cranial nerves is correctly paired with its lesion?

      Your Answer: The abducens nerve: the eye is unable to look medially

      Correct Answer: The oculomotor nerve: the eye appears to look ‘down and out’

      Explanation:

      The following are the lesions of the cranial nerves:
      1. Olfactory nerve (I)
      Reduced taste and smell, but not to ammonia which stimulates the pain fibres carried in the trigeminal nerve

      2. Optic nerve (II)
      Manifested by visual field defects, pupillary abnormalities, optic neuritis, optic atrophy, papilledema

      3. Oculomotor nerve (III)
      A fixed, dilated pupil which doesn’t accommodate, ptosis, complete internal ophthalmoplegia (masked by ptosis), unopposed lateral rectus causes outward deviation of the eye. If the ocular sympathetic fibres are also affected behind the orbit, the pupil will be fixed but not dilated.

      4. Trochlear nerve (IV)
      Diplopia due to weakness of downward and inward eye movement. The most common cause of a pure vertical diplopia. The patient tends to compensate by tilting the head away from the affected side.

      5. Trigeminal nerve (V)
      Reduced sensation or dysesthesia over the affected area. Weakness of jaw clenching and side-to-side movement. If there is a lower motor neuron (LMN) lesion, the jaw deviates to the weak side when the mouth is opened. There may be fasciculation of temporalis and masseter.

      6. Abducens nerve (VI)
      Inability to look laterally. The eye is deviated medially because of unopposed action of the medial rectus muscle.

      7. Facial nerve (VII)
      Facial weakness. In an LMN lesion the forehead is paralysed – the final common pathway to the muscles is destroyed; whereas the upper facial muscles are partially spared in an upper motor neurone (UMN) lesion because of alternative pathways in the brainstem. There appear to be different pathways for voluntary and emotional movement. CVAs usually weaken voluntary movement, often sparing involuntary movements (e.g., spontaneous smiling). The much rarer selective loss of emotional movement is called mimic paralysis and is usually due to a frontal or thalamic lesion.

      8. Vestibulocochlear nerve (VIII)
      Unilateral sensorineural deafness, tinnitus. Slow-growing lesions seldom present with vestibular symptoms as compensation has time to occur.

      9. Glossopharyngeal nerve (IX)
      Unilateral lesions do not cause any deficit because of bilateral corticobulbar connections. Bilateral lesions result in pseudobulbar palsy. These nerves are closely interlinked.

      10. Vagus nerve (X)
      Palatal weakness can cause ‘nasal speech’ and nasal regurgitation of food. The palate moves asymmetrically when the patient says ‘ahh’. Recurrent nerve palsy results in hoarseness, loss of volume and ‘bovine cough’.

      11. Accessory nerve (XI)
      Weakness and wasting of sternocleidomastoid and trapezius muscles

      12.Hypoglossal nerve (XII)
      An LMN lesion produces wasting of the ipsilateral side of the tongue, with fasciculation; and on attempted protrusion the tongue deviates towards the affected side, but the tongue deviates away from the side of a central lesion.

    • This question is part of the following fields:

      • Anatomy
      • Central Nervous System
      114
      Seconds
  • Question 20 - A 25-year-old athlete suffers an injury to the nerve that innervates the gluteus...

    Correct

    • A 25-year-old athlete suffers an injury to the nerve that innervates the gluteus minimus muscle.

      Which of the following nerves innervates the gluteus minimus muscle?

      Your Answer: Superior gluteal nerve

      Explanation:

      Gluteus minimus is the smallest muscle of the glutei. It is located just beneath the gluteus medius muscle. Gluteus minimus predominantly acts as a hip stabilizer and abductor of the hip.
      The superior gluteal nerve innervates the gluteus minimus.

    • This question is part of the following fields:

      • Anatomy
      • Lower Limb
      10.3
      Seconds
  • Question 21 - A 30 year old man presents to ED after a road traffic accident....

    Correct

    • A 30 year old man presents to ED after a road traffic accident. Free intraperitoneal fluid is found on FAST (Focussed assessment for sonography in trauma) done in the supine position.

      Which of these is most likely to be affected?

      Your Answer: Hepatorenal recess

      Explanation:

      Fluid accumulates most often in the hepatorenal pouch (of Morrison) in a supine patient. The hepatorenal pouch is located behind the liver and anterior to the right kidney and is the lowest space in the peritoneal cavity in the supine position.

      Although the vesicouterine and rectouterine spaces are also potential spaces for fluid accumulation, fluid accumulation in them occur in the erect position.

    • This question is part of the following fields:

      • Abdomen
      • Anatomy
      35.6
      Seconds
  • Question 22 - A 29-year-old woman with a skin infection not responding to first-line antibiotics return...

    Incorrect

    • A 29-year-old woman with a skin infection not responding to first-line antibiotics return for a review clinic appointment. The result of her culture shows growth of methicillin-resistant Staphylococcus aureus (MRSA).

      Which among the following antibiotics is methicillin-resistant Staphylococcus aureus usually sensitive to?

      Your Answer: Imipenem

      Correct Answer: Linezolid

      Explanation:

      Historically, MRSA has been treated successfully with outpatient oral sulphonamides, clindamycin, rifampin, doxycycline, or a combination of these agents. With the development of increasing drug resistance of MRSA to these traditional antimicrobials, there has been a search for more effective antibiotics. One recent study demonstrated that vancomycin, linezolid, and quinupristin-dalfopristin were the most effective antibiotics against multiple strains of MRSA.

    • This question is part of the following fields:

      • Microbiology
      • Specific Pathogen Groups
      25.9
      Seconds
  • Question 23 - Which of the following is NOT a typical clinical feature of diabetic ketoacidosis:...

    Correct

    • Which of the following is NOT a typical clinical feature of diabetic ketoacidosis:

      Your Answer: Cheyne–Stokes respiration

      Explanation:

      Clinical features of DKA:
      Symptoms: Polyuria, polydipsia, thirst, lethargy, weight loss, nausea, vomiting, anorexia, abdominal pain, dehydration, headache, altered mental state
      Signs: Dry mucous membranes, ketotic breath, tachycardia, hypotension, Kussmaul breathing, focal signs of precipitant e.g. infection

    • This question is part of the following fields:

      • Endocrine
      • Physiology
      11.1
      Seconds
  • Question 24 - Regarding skeletal muscle, which of the following best describes the Z-line: ...

    Incorrect

    • Regarding skeletal muscle, which of the following best describes the Z-line:

      Your Answer: A line dividing the thick and the thin myofilaments

      Correct Answer: A line dividing muscle fibres into sarcomeres

      Explanation:

      Each muscle fibre is divided at regular intervals along its length into sarcomeres separated by Z-lines. The sarcomere is the functional unit of the muscle.

    • This question is part of the following fields:

      • Basic Cellular
      • Physiology
      23.7
      Seconds
  • Question 25 - An very unwell patient is receiving treatment in your hospital's HDU and is...

    Incorrect

    • An very unwell patient is receiving treatment in your hospital's HDU and is found to have an Escherichia coli O157 infection.

      Which one of these statements about Escherichia coli O157 is true?

      Your Answer: It is enteroaggregative

      Correct Answer: Haemolytic uraemic syndrome develops in approximately 6% of patients

      Explanation:

      Escherichia coli O157 is a serotype of Escherichia coli.
      The Escherichia coliO157 strain is ‘enterohaemorrhagic’ and causes severe forms of acute haemorrhagic diarrhoea. It can also cause non-haemorrhagic diarrhoea.

      Incubation period of Escherichia coli O157 is usually 3-4 days and bloody diarrhoea usually begins on the 3rd or 4th day of the infection.

      Infections with Escherichia coliO157 are more common during the warmer months than in winter.

      Haemolytic uraemic syndrome develops in approximately 6% of patients. It is commonly seen in children and in the elderly.

      Escherichia coli O157 can also cause:
      Haemorrhagic colitis
      Haemolytic uraemic syndrome
      Thrombotic thrombocytopenic purpura but not immune thrombocytopenic purpura.

    • This question is part of the following fields:

      • Microbiology
      • Specific Pathogen Groups
      17.3
      Seconds
  • Question 26 - A 38-year-old woman presented to the emergency room after an incident of slipping...

    Incorrect

    • A 38-year-old woman presented to the emergency room after an incident of slipping and falling onto her back and left hip. Upon physical examination, it was noted that she has pain on hip flexion, but normal hip adduction. Which of the following muscles was most likely injured in this case?

      Your Answer: Gracilis

      Correct Answer: Sartorius

      Explanation:

      The hip adductors are a group of five muscles located in the medial compartment of the thigh. These muscles are the adductor longus, adductor brevis, adductor magnus, gracilis, and pectineus.

      The hip flexors consist of 5 key muscles that contribute to hip flexion: iliacus, psoas, pectineus, rectus femoris, and sartorius.

    • This question is part of the following fields:

      • Anatomy
      • Lower Limb
      26.4
      Seconds
  • Question 27 - Which of the following nerves has been damaged when a patient presents with...

    Incorrect

    • Which of the following nerves has been damaged when a patient presents with a foot drop?

      Your Answer: Obturator nerve

      Correct Answer: Common peroneal nerve

      Explanation:

      The common peroneal nerve often referred to as the common fibular nerve, is a major nerve that innervates the lower extremity. It is one of the two major branches off the sciatic nerve and receives fibres from the posterior divisions of L4 through S2 nerve roots. The common peroneal nerve separates from the sciatic nerve in the distal posterior thigh proximal to the popliteal fossa. After branching off of the sciatic nerve, it continues down the thigh, running posteroinferior to the biceps femoris muscle, and crosses laterally to the head of the lateral gastrocnemius muscle through the posterior intermuscular septum. The nerve then curves around the fibular neck before dividing into two branches, the superficial peroneal nerve (SPN) and the deep peroneal nerve (DPN). The common peroneal nerve does not have any motor innervation before dividing; however, it provides sensory innervation to the lateral leg via the lateral sural nerve.

      The superficial peroneal nerve innervates the lateral compartment of the leg, and the deep peroneal nerve innervates the anterior compartment of the leg and the dorsum of the foot. These two nerves are essential in the eversion of the foot and dorsiflexion of the foot, respectively. The superficial and deep peroneal nerves provide both motor and sensory innervation.

      The most common presentation with common peroneal nerve injury or palsy is acute foot drop, although symptoms may be progressive and can include sensory loss or pain. Weakness in foot eversion may occur if the superficial peroneal nerve component is involved.

    • This question is part of the following fields:

      • Anatomy
      • Lower Limb
      42.3
      Seconds
  • Question 28 - Regarding the hard palate, which of the following statements is CORRECT: ...

    Incorrect

    • Regarding the hard palate, which of the following statements is CORRECT:

      Your Answer: The anterior three-quarters of the hard palate is formed by the palatine bones.

      Correct Answer: Lymphatic vessels from the palate usually drain into deep cervical lymph nodes.

      Explanation:

      Lymphatic vessels from the pharynx and palate drain into the deep cervical lymph nodes.

    • This question is part of the following fields:

      • Anatomy
      • Head And Neck
      88.7
      Seconds
  • Question 29 - Which patient group are most commonly associated with infection with Klebsiella spp: ...

    Incorrect

    • Which patient group are most commonly associated with infection with Klebsiella spp:

      Your Answer: University students

      Correct Answer: Hospitalised patients

      Explanation:

      Klebsiella spp. are facultatively anaerobic Gram-negative rods, found in the normal intestinal and respiratory flora. These organisms are usually opportunistic pathogens that cause nosocomial infections, most commonly pneumonia and UTI.

    • This question is part of the following fields:

      • Microbiology
      • Pathogens
      30
      Seconds
  • Question 30 - Which one these is an example of a cause of an exudate? ...

    Incorrect

    • Which one these is an example of a cause of an exudate?

      Your Answer:

      Correct Answer: Subphrenic abscess

      Explanation:

      An exudate is an inflammatory fluid emanating from the intravascular space due to changes in the permeability of the surrounding microcirculation.

      Some common causes of exudates are: pneumonia, empyema, lung cancer, breast cancer, cancer of the pleura, SLE, rheumatoid arthritis, pericarditis, subphrenic abscess, chylothorax.

      Myxoedema, nephrotic syndrome, congestive cardiac failure, and liver cirrhosis all cause TRANSUDATE.

    • This question is part of the following fields:

      • General Pathology
      • Pathology
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SESSION STATS - PERFORMANCE PER SPECIALTY

Pathology (5/7) 71%
Wound Healing (1/1) 100%
General Pathology (1/2) 50%
Haematology (1/2) 50%
Immune Responses (1/1) 100%
Anatomy (2/9) 22%
Lower Limb (1/5) 20%
Cardiovascular Pharmacology (0/1) 0%
Pharmacology (1/3) 33%
Microbiology (3/6) 50%
Pathogens (2/2) 100%
Physiology (2/4) 50%
Respiratory Physiology (0/1) 0%
Inflammatory Responses (1/1) 100%
Principles Of Microbiology (1/2) 50%
Cranial Nerve Lesions (0/1) 0%
Cardiovascular (0/1) 0%
Renal (1/1) 100%
Respiratory (1/1) 100%
Infections (0/1) 0%
Central Nervous System (0/1) 0%
Abdomen (1/1) 100%
Specific Pathogen Groups (0/2) 0%
Endocrine (1/1) 100%
Head And Neck (0/1) 0%
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