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Question 1
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Which of the following statements is true regarding Bell's palsy in childhood?
Your Answer: Commonly preceded by a viral infection
Explanation:While the cause for Bell’s palsy is still under debate, it is observed that Bell’s palsy is often preceded by a viral infection. Bell’s Palsy:Bell’s palsy (idiopathic facial palsy) is an acute unilateral lower motor neurone palsy. It typically occurs two weeks after viral infection such as Epstein–Barr, herpes simplex, herpes zoster or mumps. A careful assessment may suggest an alternative aetiology for the acute onset of weakness, e.g. acute otitis media, Lyme disease, hypertension. Causes:In childhood, Bell’s palsy is probably a post-infectious (i.e. immune-mediated) phenomenon, while in adults, there is increasing evidence that the majority of cases follow reactivation of previous HSV infection. Management:The prognosis is generally good in childhood with full recovery in the majority. However, permanent weakness is observed in around 5%. Steroids and acyclovir may have some benefit in adults with recent onset of weakness, but the evidence of the treatment benefit is much less convincing in childhood. Exposure keratitis is an important complication and children should be managed with eye drops and taping of the eyelid at night until recovery is complete.
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This question is part of the following fields:
- Neurology And Neurodisability
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Question 2
Incorrect
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Which of the following is true regarding the anterior pituitary gland?
Your Answer: Defects in the anterior pituitary gland can cause diabetes insipidus
Correct Answer: The majority of hormone production occurs in the pars distalis
Explanation:The pituitary gland synthesizes and releases various hormones that affect several organs throughout the body.The pituitary gland is entirely ectodermal in origin but is composed of 2 functionally distinct structures that differ in embryologic development and anatomy: the adenohypophysis (anterior pituitary) and the neurohypophysis (posterior pituitary).The anterior pituitary has three main regions:Pars distalis: Where the main hormone production occursPars tuberalis: Joins the pituitary stalk arising from the posterior pituitary glandPars intermedia: Divides the anterior and posterior parts of the pituitary gland. The pars distalis forms the majority of the adenohypophysis and resembles a typical endocrine gland.
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This question is part of the following fields:
- Endocrinology
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Question 3
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A 16-year-old girl was brought to the ED by her gym instructor after developing severe shortness of breath and chest pain at the gym. She has a history of asthma since childhood. Her skin colour looked normal| however, breath sounds were found to be diminished on auscultation of the right lung. Which investigation will you order first?
Your Answer: Chest x-ray
Explanation:Asthma patients have an increased risk of developing complications like pneumonia or collapsed lung. A clear visualization of the lungs through a CXR will define the management necessary for this patient.
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This question is part of the following fields:
- Respiratory
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Question 4
Correct
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Intussusception is characterized by which of the following statements?
Your Answer: It is associated with Meckel's diverticulum
Explanation:Intussusception is one of the common causes of intestinal obstruction in children, resulting from the invagination or telescoping of one segment of the bowel into the other distal segment. It may induce bowel ischemia and necrosis, as well. It can occur as a complication of Meckel’s diverticulum. It usually occurs proximal to the ileocecal valve, and the most common presentation is ileocecal. Early signs and symptoms include cramping abdominal pain, nausea, vomiting, and pulling legs up to chest area. First line treatment includes resuscitation with IV fluids and nasogastric tube. It responds well to air-enema, which is also diagnostic.
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This question is part of the following fields:
- Emergency Medicine
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Question 5
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A 15 year old girl presented to the emergency with a history of chronic cough, fever and weight loss. Her chest X-ray showed multiple nodules 1-4 cm in size and some of them with cavitation especially in the upper lobe. A sputum sample was positive for acid fast bacilli. Which of the following cells played a part in the development of the lung lesions?
Your Answer: Macrophage
Explanation:The characteristic cells in granulomatous inflammation are giant cells, formed from merging macrophages and epithelioid cells elongated with granular eosinophilic cytoplasm. Granulomatous reactions are seen in patients with tuberculosis. A tuberculous/caseating granuloma is characterised by a zone of central necrosis lined with giant multinucleated giant cells (Langhans cells) and surrounded by epithelioid cells, lymphocytes and fibroblasts. The caseous zone is present due to the damaged and dead giant cells and epithelioid cells.
Mast cells are only few in number and fibroblasts lay down collagen.
Basophils are not present.
The giant cell made up of macrophages are the most abundant cells in this inflammatory process. -
This question is part of the following fields:
- Respiratory
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Question 6
Incorrect
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A 10-year-old boy with faecal soiling secondary to constipation and overflow incontinence has not responded to over a year of medical management.A colonoscopy-guided biopsy has ruled out Hirschsprung's disease.Which of the following procedures would be appropriate in the surgical management of this child?
Your Answer: Left hemi-colectomy to increase transit time
Correct Answer: Appendicostomy for anterior continence enemas
Explanation:The most appropriate procedure in the surgical management of this child would be to perform an appendicostomy for anterior continence enemas (Malone procedure).Idiopathic constipation leading to faecal incontinence is managed in a stepwise progression, first with laxatives such as movicol, enemas and stronger laxatives and in younger children inter-sphincteric injection of botox may be performed. Following this either anal irrigation or antegrade continence enemas are performed. Appendicostomy for anterior continence enemas allow colonic washouts and thereby rapid achievement of continence.Other options:- Defunctioning Ileostomy: Although an option in extreme cases, an ACE stoma would be more appropriate in this child.- Laparotomy for resection of the megarectum is performed if ACE stoma fails due to megarectum.- Left hemicolectomy is a procedure reserved for slow-transit colons to increase transit time.- Bishop-Koop stoma: It is a procedure of historical significance. It is a way of washing out and managing meconium ileus.
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This question is part of the following fields:
- Paediatric Surgery
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Question 7
Incorrect
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This equation links lung function measurement to height: Lung function = 2.3 + (1.5 × height), R = 0.75Which of the following statements is true?
Your Answer: The average change in lung function for a unit change in height is significant
Correct Answer: Taller individuals have higher lung functions
Explanation:The equation, lung function = 3.2 + (1.7 x height) is linear, but this does not necessarily mean that the relationship itself is linear. The equation is able to predict that taller individuals are more likely to have greater lung functions. No information is given on whether the coefficients and the R value are statistically significant.
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This question is part of the following fields:
- Epidemiology And Statistics
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Question 8
Incorrect
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A child is admitted with a febrile illness. Which of the following is of concern?
Your Answer: A 2 year old boy with heart rate of 140
Correct Answer: A 6 month old with a systolic blood pressure of 60
Explanation:Age (years) Respiratory rate (per minute) Heart rate (per minute) Systolic blood pressure<1 30-40 110-160 70-901-2 25-35 100-150 80-952-5 25-30 95-140 80-1005-12 20-25 80-120 90-110>12 15-20 60-100 100-120Adapted from Advanced Paediatric Life Support Manual
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This question is part of the following fields:
- Emergency Medicine
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Question 9
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A mother attends the clinic with her 4-year-old. She has noticed a discharge from the his left ear over the past two weeks. He has a history of frequent episodes of ‘ear infection’ but has been otherwise well. There is no reported fever. On examination, the child is systemically well. The child is co-operative with otoscopy which shows an intact pink tympanic membrane on the right but a possible perforation on the left. What is the next best step in management?
Your Answer: Refer for ENT opinion
Explanation:The child has Chronic suppurative otitis media (CSOM) which is defined as a perforated tympanic membrane with persistent drainage from the middle ear for more than 2-6 weeks.CSOM differs from chronic serous otitis media in that chronic serous otitis media may be defined as a middle ear effusion without perforation that is reported to persist for more than 1-3 months. Patients with chronic suppurative otitis media (CSOM) present with a draining ear of some duration and a premorbid history of recurrent acute otitis media, traumatic perforation, or the placement of ventilation tubes. Typically, they deny pain or discomfort. A common presenting symptom is hearing loss in the affected ear. Reports of fever, vertigo, and pain should raise concerns about infratemporal or intracranial complications. A history of persistent CSOM after appropriate medical treatment should alert the physician to consider cholesteatoma.The external auditory canal may or may not be oedematous and is not typically tender. The discharge varies from fetid, purulent, and cheese like to clear and serous. Granulation tissue is often seen in the medial canal or middle ear space. The middle ear mucosa visualized through the perforation may be oedematous or even polypoid, pale, or erythematous.
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This question is part of the following fields:
- ENT
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Question 10
Correct
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A 6 year old child presents with clinical features of nephrotic syndrome and a history of hypertension. He has normal serum cholesterol levels, however, his urine microscopy reveals oval fat bodies. Which of the following most likely represents the cause of the nephrotic syndrome?
Your Answer: Minimal change glomerulonephritis
Explanation:Minimal change glomerulonephritis presents with mild or benign urinalysis findings. However, proteinuria together with the presence of oval fat bodies are typical.Minimal change glomerulonephritis (nephropathy) accounts for most cases of childhood nephrotic syndrome and 20–25% of adult nephrotic syndrome.
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This question is part of the following fields:
- Nephro-urology
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