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  • Question 1 - In a newly diagnosed acromegaly patient, which of the following would you not...

    Correct

    • In a newly diagnosed acromegaly patient, which of the following would you not expect to find?

      Your Answer: Hypohidrosis

      Explanation:

      Features of acromegaly may include:

      • Soft tissue swelling visibly resulting in enlargement of the hands, feet, nose, lips and ears, and a general thickening of the skin
      • Soft tissue swelling of internal organs, notably the heart with associated weakening of its muscularity, and the kidneys, vocal cords (resulting in a characteristic thick, deep voice and slowing of speech)
      • Generalized expansion of the skull at the fontanelle, frontal bossing, prognathism with associated macroglossia (enlargement of the tongue) and teeth spacing.
      • Hypertrichosis, hyperpigmentation and hyperhidrosis (not hypohidrosis) may occur in these patients as well as carpal tunnel syndrome and impotence.

    • This question is part of the following fields:

      • Endocrinology
      • Medicine
      15.8
      Seconds

  • Question 2 - Which of the following factors is most likely to lead to an increase...

    Correct

    • Which of the following factors is most likely to lead to an increase in serum cortisol levels?

      Your Answer: Severe emotional stress

      Explanation:

      Cortisol is widely known as the stress hormone. Alterations in cortisol levels have been found in relation to mood disorders, illness, trauma, pain, fear, exertion, and anxiety, amongst other stimuli.

    • This question is part of the following fields:

      • Endocrinology
      • Medicine
      153.5
      Seconds

  • Question 3 - Which of the following stimulates glucagon release? ...

    Incorrect

    • Which of the following stimulates glucagon release?

      Your Answer: Glucose

      Correct Answer: Exercise

      Explanation:

      Studies have shown a small increase in glucagon levels during stress tests and exercise. This occurs in response to the reduction of blood glucose levels during physical activity; epinephrine levels are also a stimulus for the release of glucagon during exercise, since it suppresses insulin, which accounts for its stimulatory effects on glucagon. The use of stored fats for energy during exercise also stimulates the release of glucagon.

    • This question is part of the following fields:

      • Endocrinology
      • Medicine
      89.3
      Seconds

  • Question 4 - Which one of the following will increase an individual’s appetite? ...

    Incorrect

    • Which one of the following will increase an individual’s appetite?

      Your Answer: Cholecystokinin

      Correct Answer: Ghrelin

      Explanation:

      Ghrelin is a hormone which exerts a strong influence on hunger and energy balance. It helps regulate appetite by being secreted when the stomach is empty, to stimulate hunger. When the stomach is filled, its secretion stops.

    • This question is part of the following fields:

      • Endocrinology
      • Medicine
      8.5
      Seconds

  • Question 5 - Which of the following hormones cause negative feedback on the CRH/ACTH axis? ...

    Correct

    • Which of the following hormones cause negative feedback on the CRH/ACTH axis?

      Your Answer: Cortisol

      Explanation:

      The hypothalamic–pituitary–adrenal axis, also known as HPA axis is a set of interactions that regulate the secretion of several hormones through negative feedback. Cortisol, for example, is produced by the adrenal cortex, binds to its receptors in the hypothalamus and adenohypophysis and inhibits secretion of corticotropin releasing hormone (CRH) and adrenocorticotropic hormone (ACTH). The drop in CRH secretion leads to a decrease in ACTH secretion, which in turn causes less cortisol to be secreted.

    • This question is part of the following fields:

      • Endocrinology
      • Medicine
      6.9
      Seconds

  • Question 6 - Which of the flowing plasma proteins has the greatest affinity for T4? ...

    Correct

    • Which of the flowing plasma proteins has the greatest affinity for T4?

      Your Answer: Thyroxin-binding globulin

      Explanation:

      There are three principal plasma thyroid hormone-binding proteins, thyroxine-binding globulin (TBG), transthyretin (TTR), and albumin. TBG is synthesized in the liver and due to its relatively high affinity for iodothyronines, binds and carries approximately 70–75% of circulating T4 and T3.

    • This question is part of the following fields:

      • Endocrinology
      • Medicine
      4.7
      Seconds

  • Question 7 - What is the most common cause of primary hyperaldosteronism? ...

    Correct

    • What is the most common cause of primary hyperaldosteronism?

      Your Answer: Bilateral idiopathic adrenal hyperplasia

      Explanation:

      Primary aldosteronism, also known as primary hyperaldosteronism or Conn’s syndrome, is excess production of the hormone aldosterone by the adrenal glands resulting in low renin levels. Primary hyperaldosteronism has a number of causes. About 66% of cases are due to enlargement of both adrenal glands and 33% of cases are due to an adrenal adenoma that produces aldosterone. Other uncommon causes include adrenal cancer and an inherited disorder called familial hyperaldosteronism

    • This question is part of the following fields:

      • Endocrinology
      • Medicine
      6.2
      Seconds

  • Question 8 - Which hormone is associated with the temperature surge in hot flushes? ...

    Correct

    • Which hormone is associated with the temperature surge in hot flushes?

      Your Answer: LH

      Explanation:

      Luteinizing hormone or LH is a hormone produced by the anterior pituitary gland. Studies have shown surges in LH levels during menopausal hot flushes, suggesting that a pulsatile release of LH is responsible for increased hypothalamic norepinephrine activity, causing the hot flushes.

    • This question is part of the following fields:

      • Endocrinology
      • Medicine
      4.2
      Seconds

  • Question 9 - Which of the following skin coloration abnormalities occurs due to adrenal insufficiency due...

    Correct

    • Which of the following skin coloration abnormalities occurs due to adrenal insufficiency due to primary adrenal disease?

      Your Answer: Hyperpigmentation

      Explanation:

      Addison’s disease, also known as primary adrenal insufficiency, or hypocortisolism is an endocrine disorder. Hyperpigmentation is one of its most common signs; it occurs as a result of an increase in pro-opiomelanocortin to produce more ACTH in response to the decreased levels of cortisol. Pro-opiomelanocortin is a precursor of melanocyte stimulating hormone (MSH), which stimulates melanocytes, causing darkening of the skin.

    • This question is part of the following fields:

      • Endocrinology
      • Medicine
      15.2
      Seconds

  • Question 10 - Growth hormone deficiency causes? ...

    Correct

    • Growth hormone deficiency causes?

      Your Answer: Decreased epiphyseal growth

      Explanation:

      Growth hormone deficiency is caused by conditions affecting the pituitary gland, such as tumours. Its effects depend on the age of the patient: in infancy and childhood, growth failure is most likely to occur. The epiphyseal plate is the area in long bones where growth occurs, and it is the area affected by growth hormone deficiency. Poor growth/shortness is the main symptom of GH deficiency in children, usually resulting in growth at about half the usual rate for age.

    • This question is part of the following fields:

      • Endocrinology
      • Medicine
      4
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Endocrinology (8/10) 80%
Medicine (8/10) 80%
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