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  • Question 1 - Regarding haemophilia A, which of the following statements is INCORRECT: ...

    Incorrect

    • Regarding haemophilia A, which of the following statements is INCORRECT:

      Your Answer: Haemophilia A is caused by a deficiency of factor VIII.

      Correct Answer: In haemophilia both the APTT and PT are prolonged.

      Explanation:

      Haemophilia A is the most common of the hereditary clotting factor deficiencies. The inheritance is sex-linked but up to one-third of patients have no family history and these cases result from recent mutation. The vast majority of cases are inherited in an X-linked recessive fashion, affecting males born to carrier mothers. Females born to affected fathers can also, rarely, be affected due to homozygosity for the gene, where there is marriage to close relatives.

      The defect is an absence or low level of plasma factor VIII. The APTT is prolonged but the PT is normal. Recurrent painful haemarthroses and muscle haematomas dominate the clinical course of severely affected patients and if inadequately treated, lead to progressive joint deformity and disability. Local pressure can cause entrapment neuropathy or ischaemic necrosis. Prolonged bleeding occurs after dental extractions or post-trauma. Spontaneous haematuria and gastrointestinal haemorrhage may occur. The clinical severity of the disease correlates inversely with the factor VIII level. Operative and post-traumatic haemorrhage are life-threatening both in severely and mildly affected patients.

    • This question is part of the following fields:

      • Haematology
      • Pathology
      19
      Seconds
  • Question 2 - What is the earliest physiological effect that causes postural hypotension: ...

    Incorrect

    • What is the earliest physiological effect that causes postural hypotension:

      Your Answer: A fall in stroke volume

      Correct Answer: A fall in central venous pressure

      Explanation:

      When autonomic reflexes are impaired or intravascular volume is markedly depleted, a significant reduction in blood pressure occurs upon standing, a phenomenon termed Postural Hypotension (orthostatic hypotension). Orthostatic hypotension can cause dizziness, syncope, and even angina or stroke. When autonomic reflexes are impaired, blood pressure falls progressively after standing because the gravitational pooling of blood in the legs cannot be compensated by sympathetic vasoconstriction.

    • This question is part of the following fields:

      • Cardiovascular
      • Physiology
      11.4
      Seconds
  • Question 3 - For the treatment of his atrial fibrillation, a 67-year-old man is about to...

    Incorrect

    • For the treatment of his atrial fibrillation, a 67-year-old man is about to begin taking warfarin. He also takes a number of other medications.

      Which of the following medications will prevent warfarin from working?

      Your Answer: Sodium valproate

      Correct Answer: Phenytoin

      Explanation:

      Many medications, including warfarin, require cytochrome P450 enzymes for their metabolism. When co-prescribing cytochrome p450 enzyme inducers and inhibitors with warfarin, it’s critical to be cautious.

      Inhibitors of the cytochrome p450 enzyme inhibit the effects of warfarin, resulting in a lower INR. To remember the most commonly encountered cytochrome p450 enzyme inducers, use the mnemonic PC BRASS:

      P– Phenytoin
      C– Carbamazepine
      B– Barbiturates
      R– Rifampicin
      A– Alcohol (chronic ingestion)
      S– Sulphonylureas
      S– Smoking

    • This question is part of the following fields:

      • Cardiovascular Pharmacology
      • Pharmacology
      21.1
      Seconds
  • Question 4 - A newborn baby is rushed to the neonatal ICU 4 hours after birth...

    Incorrect

    • A newborn baby is rushed to the neonatal ICU 4 hours after birth due to sudden onset severe jaundice and generalised oedema. Family history reveals that this is the second baby, while blood testing shows that the mother has an Rh-negative blood group while the baby is Rh-positive. A diagnosis of haemolytic disease of the newborn is established.

      Which one of the following hypersensitivity reactions have occurred in this case?

      Your Answer: Type I hypersensitivity reaction

      Correct Answer: Type II hypersensitivity reaction

      Explanation:

      Hepatitis A usually doesn’t pose a special risk to a pregnant woman or her baby. Maternal infection doesn’t result in birth defects, and a mother typically doesn’t transmit the infection to her baby. HAV is almost always transmitted by the faecal-oral route and is usually acquired through close personal contact or via contaminated food.

      When a woman has chickenpox in the first 20 weeks of pregnancy, there is a 1 in 50 chance for the baby to develop a set of birth defects. This is called the congenital varicella syndrome. It includes scars, defects of muscle and bone, malformed and paralyzed limbs, small head size, blindness, seizures, and intellectual disability.

      TORCH Syndrome refers to infection of a developing foetus or newborn by any of a group of infectious agents. “TORCH” is an acronym meaning (T)oxoplasmosis, (O)ther Agents, (R)ubella (also known as German Measles), (C)ytomegalovirus, and (H)erpes Simplex.
      Infection with any of these agents may cause a constellation of similar symptoms in affected newborns. These may include fever; difficulties feeding; small areas of bleeding under the skin, causing the appearance of small reddish or purplish spots; enlargement of the liver and spleen (hepatosplenomegaly); yellowish discoloration of the skin, whites of the eyes, and mucous membranes (jaundice); hearing impairment; abnormalities of the eyes; and other symptoms and findings.

    • This question is part of the following fields:

      • General Pathology
      • Pathology
      28.7
      Seconds
  • Question 5 - A 71-year-old patient has been diagnosed with a dopamine-secreting neuroendocrine tumour.

    Which of the...

    Incorrect

    • A 71-year-old patient has been diagnosed with a dopamine-secreting neuroendocrine tumour.

      Which of the following statements about dopamine is correct?

      Your Answer: It is a peptide hormone

      Correct Answer: It inhibits prolactin release from the anterior pituitary

      Explanation:

      Dopamine is a neurotransmitter and amine hormone that is derived from the amino acid tyrosine. It is made in a number of places throughout the human body, both inside and outside the central nervous system. The adrenal medulla, dopamine neurons in the arcuate nucleus of the hypothalamus, the substantia nigra, and other areas of the brain produce dopamine.

      The tuberoinfundibular pathway refers to the dopamine neurons in the arcuate nucleus of the hypothalamus’ tubeal region. Dopamine is discharged into the hypothalamo-hypophyseal portal system from these neurons’ neurosecretory terminals at the median eminence.

      The major function of dopamine produced from the hypothalamus is to suppress prolactin production from the anterior pituitary, and it is released in reaction to excessive levels of prolactin secretion. Modulation of motor-control centres and activation of reward centres are two more crucial activities of the brain.
      Dopamine-secreting cells can also be found in other areas of the body, where they perform mostly paracrine functions (acting on nearby cells).

    • This question is part of the following fields:

      • Endocrine Physiology
      • Physiology
      22.3
      Seconds
  • Question 6 - What is the main route of transmission of Mumps? ...

    Correct

    • What is the main route of transmission of Mumps?

      Your Answer: Respiratory droplet route

      Explanation:

      Mumps is primarily transmitted person to person via respiratory droplets.

    • This question is part of the following fields:

      • Microbiology
      • Pathogens
      12.3
      Seconds
  • Question 7 - Which of the following best describes the order in which blood passes through...

    Incorrect

    • Which of the following best describes the order in which blood passes through the nephron?

      Your Answer: Efferent arteriole→Glomerular capillary→Afferent arteriole→Peritubular capillary→Vasa recta

      Correct Answer: Afferent arteriole→Glomerular capillary→Efferent arteriole→Peritubular capillary→Vasa recta

      Explanation:

      The nephron’s blood flow is as follows:
      Afferent arteriole – Glomerular capillary – Efferent arteriole – Peritubular capillary – Vasa recta – Afferent arteriole – Glomerular capillary – Efferent arteriole – Peritubular capillary – Vasa recta

      The kidney is the only vascular network in the body with two capillary beds. With arterioles supplying and draining the glomerular capillaries, higher hydrostatic pressures at the glomerulus are maintained, allowing for better filtration. A second capillary network at the tubules enables for secretion and absorption in the tubules, as well as concentrating urine.

    • This question is part of the following fields:

      • Physiology
      • Renal Physiology
      14
      Seconds
  • Question 8 - The primary mechanism of action of ketamine is: ...

    Incorrect

    • The primary mechanism of action of ketamine is:

      Your Answer: Gamma-aminobutyric acid (GABA)-receptor antagonist

      Correct Answer: N-methyl-D-aspartate (NMDA)-receptor antagonist

      Explanation:

      Ketamine is a non-competitive antagonist of the calcium-ion channel in the NMDA (N-methyl-D-aspartate) receptor. It further inhibits the NMDA-receptor by binding to its phencyclidine binding site. Ketamine also acts at other receptors as an opioid receptor agonist (analgesic effects), as an muscarinic anticholinergic receptor antagonist (antimuscarinic effects) and by blocking fast sodium channels (local anaesthetic effect).

      Overdose may lead to panic attacks and aggressive behaviour; rarely seizures, increased ICP, and cardiac arrest

      Very similar in chemical makeup to PCP (phencyclidine), but it is shorter acting and less toxic

    • This question is part of the following fields:

      • Anaesthesia
      • Pharmacology
      13.2
      Seconds
  • Question 9 - A 25-year-old female arrives at the emergency room with a severe case of asthma....

    Incorrect

    • A 25-year-old female arrives at the emergency room with a severe case of asthma. When she doesn't seem to be improving after initial treatment, you decide to start an aminophylline infusion.

      From the options below, which is Aminophylline's main mechanism of action?

      Your Answer: Alpha receptor antagonism

      Correct Answer: Phosphodiesterase inhibition

      Explanation:

      Theophylline and Ethylenediamine are combined in a 2:1 ratio to form Aminophylline. Its solubility is improved by the addition of Ethylenediamine. It has a lower potency and a shorter duration of action than Theophylline.
      It is used to treat the following conditions:
      Heart failure
      It is used to treat the following conditions:
      COPD
      Bradycardias

      Aminophylline has the following properties:
      Phosphodiesterase inhibitor that increases intracellular cAMP and relaxes smooth muscle in the bronchial airways and pulmonary blood vessels.
      Mast cell stabilization is achieved by using a non-selective adenosine receptor antagonist.
      It has slight positive inotropic and chronotropic effects, increasing cardiac output and decreasing systemic vascular resistance, lowering arterial blood pressure. It has been used historically in the treatment of refractory heart failure and is indicated by the current ALS guidelines as a substitute treatment for bradycardia.

      The daily oral dose for adults is 900 mg, divided into 2-3 doses. For severe asthma or COPD, a loading dosage of 5 mg/kg over 10-20 minutes is given, followed by a continuous infusion of 0.5 mg/kg/hour. The therapeutic range is small (10-20 microgram/ml), hence assessments of aminophylline plasma concentrations are useful during long-term treatment.

    • This question is part of the following fields:

      • Pharmacology
      • Respiratory Pharmacology
      32.4
      Seconds
  • Question 10 - A 30-year old male is taken to the emergency room after suffering a...

    Incorrect

    • A 30-year old male is taken to the emergency room after suffering a blunt trauma to the abdomen. He is complaining of severe abdominal pain, however all his other vital signs remain stable. A FAST scan is performed to assess for hemoperitoneum.

      If hemoperitoneum is present, it is most likely to be observed in which of the following areas?

      Your Answer: Spleen

      Correct Answer: Liver

      Explanation:

      The Focused Assessment with Sonography in Trauma (FAST) is an ultrasound protocol developed to assess for hemoperitoneum and hemopericardium. Numerous studies have demonstrated sensitivities between 85% to 96% and specificities exceeding 98%.

      The FAST exam evaluates four regions for pathologic fluid: (1) the right upper quadrant, (2) the subxiphoid (or subcostal) view, (3) the left upper quadrant, and (4) the suprapubic region.

      The right upper quadrant (RUQ) visualizes the hepatorenal recess, also known as Morrison’s pouch, the right paracolic gutter, the hepato-diaphragmatic area, and the caudal edge of the left liver lobe. The probe is positioned in the sagittal orientation along the patient’s flank at the level of the 8 to 11 rib spaces. The hand is placed against the bed to ensure visualization of the retroperitoneal kidney. The RUQ view is the most likely to detect free fluid with an overall sensitivity of 66%. Recent retrospective evidence suggests the area along the caudal edge of the left lobe of the liver has the highest sensitivity, exceeding 93%.

    • This question is part of the following fields:

      • Abdomen And Pelvis
      • Anatomy
      28.6
      Seconds
  • Question 11 - Regarding dynamic compression of the airways, which of the following statements is CORRECT:...

    Correct

    • Regarding dynamic compression of the airways, which of the following statements is CORRECT:

      Your Answer: It occurs during forced expiration.

      Explanation:

      Dynamic compression occurs because as the expiratory muscles contract during forced expiration, all the structures within the lungs, including the airways, are compressed by the positive intrapleural pressure. Consequently the smaller airways collapse before the alveoli empty completely and some air remains within the lungs (the residual volume). Physiologically this is important as a completely deflated lung with collapsed alveoli requires significantly more energy to inflate. Dynamic compression does not occur in normal expiration because the intrapleural pressure is negative throughout the whole cycle.

    • This question is part of the following fields:

      • Physiology
      • Respiratory
      14.3
      Seconds
  • Question 12 - The last two segments of the nephrons are the distal convoluted tubule (DCT)...

    Incorrect

    • The last two segments of the nephrons are the distal convoluted tubule (DCT) and collecting duct (CD).

      Which cell reabsorbs sodium more in the late DCT and CD?

      Your Answer: Chief cells

      Correct Answer: Principal cells

      Explanation:

      The main Na+ reabsorbing cells in the late distal convoluted tubule and collecting duct are the principal cells. These make up the majority of the tubular cells.

      The exchange is driven by the Na.K.ATPase pumps on the basolateral membrane.

    • This question is part of the following fields:

      • Physiology
      • Renal Physiology
      21.1
      Seconds
  • Question 13 - What is the correct adrenaline dose for a patient with pulseless ventricular tachycardia?...

    Incorrect

    • What is the correct adrenaline dose for a patient with pulseless ventricular tachycardia?

      Your Answer: 0.5 ml of 1 in 10,000 adrenaline solution

      Correct Answer: 10 ml of 1 in 10,000 adrenaline solution

      Explanation:

      Ventricular fibrillation or pulseless ventricular tachycardia (VF/VT) are referred to as shockable rhythm.

      IV adrenaline 1 mg (10 mL of 1:10,000 solution) should be administered after 3 shocks and every 3 – 5 minutes/after alternate shocks thereafter for a shockable rhythm.

      For a non-shockable rhythm, 1 mg IV adrenaline should be administered as soon as IV access is obtained, and then every 3 – 5 minutes/after alternate shocks thereafter.

    • This question is part of the following fields:

      • Cardiovascular
      • Pharmacology
      9.1
      Seconds
  • Question 14 - Regarding the refractory period, which of the following statements is INCORRECT: ...

    Incorrect

    • Regarding the refractory period, which of the following statements is INCORRECT:

      Your Answer: Action potentials cannot occur in the absolute refractory period.

      Correct Answer: Action potentials can occur in the relative refractory period but the amplitude of the action potential is smaller.

      Explanation:

      Following the action potential, Na+channels remain inactive for a time in a period known as the absolute refractory period where they cannot be opened by any amount of depolarisation. Following this there is a relative refractory period where the temporary hyperpolarisation (due to delayed closure of rectifier K+channels) makes the cell more difficult to depolarise and an action potential can be generated only in response to a larger than normal stimulus. The refractory period limits the frequency at which action potentials can be generated, and ensures that, once initiated, an action potential can travel only in one direction. An action potential is an all or nothing response so the amplitude of the action potential cannot be smaller.

    • This question is part of the following fields:

      • Basic Cellular
      • Physiology
      12.3
      Seconds
  • Question 15 - Which of the following statements about lithium treatment is FALSE: ...

    Incorrect

    • Which of the following statements about lithium treatment is FALSE:

      Your Answer: A serum-lithium concentration of 0.4 – 1 mmol/litre is therapeutic.

      Correct Answer: Concomitant treatment with NSAIDs decreases serum-lithium concentration.

      Explanation:

      Lithium levels are raised by NSAIDs because renal clearance is reduced. Lithium is a small ion (74 Daltons) with no protein or tissue binding and is therefore amenable to haemodialysis. Lithium is freely distributed throughout total body water with a volume of distribution between 0.6 to 0.9 L/kg, although the volume may be smaller in the elderly, who have less lean body mass and less total body water. Steady-state serum levels are typically reached within five days at the usual oral dose of 1200 to 1800 mg/day. The half-life for lithium is approximately 18 hours in adults and 36 hours in the elderly.
      Lithium is excreted almost entirely by the kidneys and is handled in a manner similar to sodium. Lithium is freely filtered but over 60 percent is then reabsorbed by the proximal tubules.

    • This question is part of the following fields:

      • Central Nervous System
      • Pharmacology
      14.2
      Seconds
  • Question 16 - Which of the following ions is more abundant in extracellular fluid than in...

    Correct

    • Which of the following ions is more abundant in extracellular fluid than in intracellular fluid:

      Your Answer: Cl -

      Explanation:

      Protein and phosphate are the primary intracellular anions, while chloride (Cl-) and bicarbonate are the predominant extracellular anions (HCO3-).

    • This question is part of the following fields:

      • Basic Cellular
      • Physiology
      13.7
      Seconds
  • Question 17 - Which of the following is NOT one of insulin's actions: ...

    Incorrect

    • Which of the following is NOT one of insulin's actions:

      Your Answer: Increased cellular potassium uptake

      Correct Answer: Increased gluconeogenesis

      Explanation:

      Insulin has a number of effects on glucose metabolism, including:
      Inhibition of glycogenolysis and gluconeogenesis
      Increased glucose transport into fat and muscle
      Increased glycolysis in fat and muscle
      Stimulation of glycogen synthesis
      By inhibiting gluconeogenesis, insulin maintains the availability of amino acids as substrates for protein synthesis. Thus, insulin supports protein synthesis through direct and indirect mechanisms.

    • This question is part of the following fields:

      • Endocrine
      • Pharmacology
      20.2
      Seconds
  • Question 18 - Regarding Clostridium tetani, which of the following statements is CORRECT: ...

    Correct

    • Regarding Clostridium tetani, which of the following statements is CORRECT:

      Your Answer: Metronidazole is usually the antibiotic of choice for tetanus infection.

      Explanation:

      Clostridium tetani infection is predominantly derived from animal faeces and soil.  Clostridium tetani has exotoxin-mediated effects, predominantly by tetanospasmin which inhibits the release of GABA at the presynaptic membrane throughout the central and peripheral nervous system. Metronidazole has overtaken penicillin as the antibiotic of choice for treatment of tetanus (together with surgical debridement, tetanus toxoid immunisation, and human tetanus immunoglobulin).

    • This question is part of the following fields:

      • Microbiology
      • Pathogens
      9.4
      Seconds
  • Question 19 - Which of the following muscles are primarily involved in passive inspiration: ...

    Incorrect

    • Which of the following muscles are primarily involved in passive inspiration:

      Your Answer: Diaphragm and internal intercostal muscles

      Correct Answer: Diaphragm and external intercostal muscles

      Explanation:

      Passive inspiration is produced by contraction of the diaphragm (depressing the diaphragm) and the external intercostal muscles (elevating the ribs). In inspiration, elevation of the sternal ends of the ribs (‘pump handle’ movement), elevation of the lateral shafts of the ribs (‘bucket handle’ movement) and depression of the diaphragm result in expansion of the thorax in an anteroposterior, transverse and vertical direction respectively. This results in an increased intrathoracic volume and decreased intrathoracic pressure and thus air is drawn into the lungs.

    • This question is part of the following fields:

      • Anatomy
      • Thorax
      10.8
      Seconds
  • Question 20 - A 29-year-old female with a swollen red finger presents to your clinic and...

    Incorrect

    • A 29-year-old female with a swollen red finger presents to your clinic and you suspect that the underlying process is of acute inflammation. You request for some bloods investigations.

      Which statement about histamine as a chemical mediator of the acute inflammatory response is TRUE?

      Your Answer: It causes vasoconstriction

      Correct Answer: It increases vascular permeability

      Explanation:

      Histamine increases vascular permeability in the acute inflammatory response.

      Histamine causes vasodilation.

      It is released from Mast cells and basophils, eosinophils and platelets.

      Mast cells and basophils are its primary source

      Nitric oxide (not histamine) is a major factor in endotoxic shock

    • This question is part of the following fields:

      • General Pathology
      • Pathology
      18
      Seconds
  • Question 21 - Regarding tapeworm, which of the following statements is CORRECT: ...

    Incorrect

    • Regarding tapeworm, which of the following statements is CORRECT:

      Your Answer: Humans may be infected by pork tapeworm or poultry tapeworm.

      Correct Answer: Diagnosis is by direct visualisation of characteristic eggs in the stool.

      Explanation:

      Diagnosis of tapeworm is by direct visualisation of characteristic eggs in stool. Humans may be infected by pork or beef tapeworm. Treatment is with praziquantel or niclosamide. Specialist advice should be sought for the management of neurocysticercosis.Iron-deficiency anaemia is typically seen in hookworm infection. Threadworms migrate from the intestine at night to lay eggs on the perianal skin. Mebendazole is first line treatment for threadworms.

    • This question is part of the following fields:

      • Microbiology
      • Pathogens
      20.3
      Seconds
  • Question 22 - Glucagon is the main catabolic hormone of the body and raises the concentration...

    Correct

    • Glucagon is the main catabolic hormone of the body and raises the concentration of glucose and fat in the bloodstream.

      Which pancreatic islet cells secretes glucagon?

      Your Answer: Alpha

      Explanation:

      Glucagon, secreted from the pancreatic islet alpha cells, is considered to be the main catabolic hormone of the body. It raises the concentration of glucose and fat in the bloodstream

      There are five different pancreatic islet cells:
      Alpha cells (20%) – produce glucagon
      Beta cells (70%) – produce insulin and amylin
      Delta cells (<10%) – produce somatostatin
      Gamma cells (<5%) – produce pancreatic polypeptide
      Epsilon cells (<1%) – produce ghrelin

    • This question is part of the following fields:

      • Endocrine Physiology
      • Physiology
      4.7
      Seconds
  • Question 23 - A 30-year-old woman presents with a history of fever and sore throat. On...

    Correct

    • A 30-year-old woman presents with a history of fever and sore throat. On examination, there is tonsillar exudate and cervical lymphadenopathy and a diagnosis of tonsillitis is made. A course of penicillin is prescribed.

      What is the mechanism of action of penicillin?

      Your Answer: Inhibition of cell wall synthesis

      Explanation:

      Penicillin is bactericidal and produces its antimicrobial action by preventing cross-linkage between the linear peptidoglycan polymer chains that make up the bacterial cell wall. This action inhibits cell wall synthesis.

    • This question is part of the following fields:

      • Infections
      • Pharmacology
      13.7
      Seconds
  • Question 24 - A 67-year-old man with chronic breathlessness is sent for a lung function test.

    Which...

    Incorrect

    • A 67-year-old man with chronic breathlessness is sent for a lung function test.

      Which statement concerning lung function testing is true?

      Your Answer: In obstructive lung disease, FVC is usually increased

      Correct Answer: In restrictive lung disease, the FEV 1 /FVC ratio is usually >0.7

      Explanation:

      In restrictive lung disease, the FEV1/FVC ratio is usually >0.7%.

      In obstructive lung disease, FEV1 is reduced to <80% of normal and FVC is usually reduced. The FEV1/FVC ratio is reduced to <0.7. Airflow obstruction is defined in the NICE guidelines as:
      Mild airflow obstruction = an FEV 1 of >80% in the presence of symptoms
      Moderate airflow obstruction = FEV 1 of 50-79%
      Severe airflow obstruction = FEV 1 of 30-49%
      Very severe airflow obstruction = FEV1<30%. Spirometry is a poor predictor of quality of life in COPD. However, it can be used as part of the assessment of severity of COPD.

    • This question is part of the following fields:

      • Physiology
      • Respiratory Physiology
      19.8
      Seconds
  • Question 25 - The mechanism of action of abciximab is by: ...

    Incorrect

    • The mechanism of action of abciximab is by:

      Your Answer:

      Correct Answer: Blocking the binding of fibrinogen to GPIIb/IIIa receptor sites

      Explanation:

      Abciximab is a glycoprotein IIb/IIIa inhibitors and prevents platelet aggregation by blocking the binding of fibrinogen to receptors on platelets.

    • This question is part of the following fields:

      • Cardiovascular
      • Pharmacology
      0
      Seconds
  • Question 26 - Which of the following statements is correct about the extensor digitorum muscle? ...

    Incorrect

    • Which of the following statements is correct about the extensor digitorum muscle?

      Your Answer:

      Correct Answer: It extends the medial four digits at the metacarpophalangeal joints

      Explanation:

      Extensor digitorum is a long muscle located in the posterior compartment of the forearm. Together with the extensor carpi ulnaris and extensor digiti minimi, extensor carpi radialis longus and brevis as well as the brachioradialis, it belongs to the group of superficial extensors of the forearm. These muscles can be easily palpated in the lateral aspect of the posterior forearm, especially during the extension of hand when they are contracted.

      Extensor digitorum runs from the lateral epicondyle of humerus to the medial four phalanges of the hand. In this way, it generates the pull for the extension of the four medial fingers in their metacarpophalangeal and both interphalangeal joints. Extensor digitorum also participates in the extension of the wrist.

      Extensor digitorum is innervated by posterior interosseous nerve which is a continuation of a deep branch of radial nerve (root value C7 and C8).

      Extensor digitorum is vascularized by the branches of three different arteries: (1) posterior interosseous artery, (2) radial recurrent artery, and (3) anterior interosseous artery. Anterior and posterior interosseous arteries are the branches of the common interosseous artery that arises from the ulnar artery. The radial recurrent artery is a branch of the radial artery.

    • This question is part of the following fields:

      • Anatomy
      • Upper Limb
      0
      Seconds
  • Question 27 - In a 7-year-old child with chickenpox, which of the following would you advise...

    Incorrect

    • In a 7-year-old child with chickenpox, which of the following would you advise the mother NOT to do?

      Your Answer:

      Correct Answer: Give ibuprofen for the fever

      Explanation:

      Chickenpox (varicella zoster) is a highly contagious airborne disease and has an incubation period of between 7-21 days. It often has a prodromal phase when there is a fever, aches and headaches, dry cough, and sore throat before onset of rash.

      Some recognized complications of chickenpox are:
      Orchitis
      Hepatitis
      Pneumonia
      Encephalitis
      Infected spots
      Otitis media
      Myocarditis
      Glomerulonephritis
      Appendicitis
      Pancreatitis

      Treatment is symptomatic and includes using paracetamol to manage fever. There is a link between use of ibuprofen in patients with chicken-pox and necrotizing fasciitis so Ibuprofen should NOT be used.

      An emollient and antihistamine can be used to ease the itchy rash and oral hydration is encouraged.

    • This question is part of the following fields:

      • Microbiology
      • Specific Pathogen Groups
      0
      Seconds
  • Question 28 - A patient is sent in to ED by her GP with hyponatraemia and...

    Incorrect

    • A patient is sent in to ED by her GP with hyponatraemia and hyperkalaemia. There is most likely to be a deficiency in which of the following hormones:

      Your Answer:

      Correct Answer: Aldosterone

      Explanation:

      A deficiency of aldosterone, as seen in adrenal insufficiency, can result in hyponatraemia and hyperkalaemia.

    • This question is part of the following fields:

      • Endocrine
      • Physiology
      0
      Seconds
  • Question 29 - Which of the following statements is correct regarding the lymphatic system? ...

    Incorrect

    • Which of the following statements is correct regarding the lymphatic system?

      Your Answer:

      Correct Answer: Lymphatic vessels contain both smooth muscle and unidirectional valves.

      Explanation:

      Fluid filtration out of the capillaries is usually slightly greater than fluid absorption into the capillaries. About 8 L of fluid per day is filtered by the microcirculation and returns to the circulation by the lymphatic system. Lymphatic capillaries drain into collecting lymphatics, then into larger lymphatic vessels. Both of these containing smooth muscle and unidirectional valves. From this point, lymph is propelled by smooth muscle constriction and vessel compression by body movements into afferent lymphatics. It then goes to the lymph nodes where phagocytes remove bacteria and foreign materials. It is here that most fluid is reabsorbed by capillaries, and the remainder returns to the subclavian veins via efferent lymphatics and the thoracic duct. The lymphatic system has a major role to play in the body’s immune defence and also has a very important role in the absorption and transportation of fats.

    • This question is part of the following fields:

      • Cardiovascular
      • Physiology
      0
      Seconds
  • Question 30 - You're taking a history of a 59-year-old banker who has had heartburn in...

    Incorrect

    • You're taking a history of a 59-year-old banker who has had heartburn in the past.

      Which of the following information about antacids is correct?

      Your Answer:

      Correct Answer: Magnesium carbonate can reduce the absorption of drugs taken at the same time

      Explanation:

      Antacids such as aluminium hydroxide and magnesium carbonate are commonly used. They’re both water-insoluble and can reduce the absorption of drugs taken together. Allow at least 1-2 hours between taking these antacids and any other medications.

      Because it reduces gastrointestinal phosphate absorption, aluminium hydroxide can also be used to treat hyperphosphatemia in patients with renal failure.

      Magnesium carbonate has a laxative effect, whereas aluminium hydroxide has a constipating effect.

    • This question is part of the following fields:

      • Gastrointestinal Pharmacology
      • Pharmacology
      0
      Seconds

SESSION STATS - PERFORMANCE PER SPECIALTY

Haematology (0/1) 0%
Pathology (0/3) 0%
Cardiovascular (0/2) 0%
Physiology (3/9) 33%
Cardiovascular Pharmacology (0/1) 0%
Pharmacology (1/7) 14%
General Pathology (0/2) 0%
Endocrine Physiology (1/2) 50%
Microbiology (2/3) 67%
Pathogens (2/3) 67%
Renal Physiology (0/2) 0%
Anaesthesia (0/1) 0%
Respiratory Pharmacology (0/1) 0%
Abdomen And Pelvis (0/1) 0%
Anatomy (0/2) 0%
Respiratory (1/1) 100%
Basic Cellular (1/2) 50%
Central Nervous System (0/1) 0%
Endocrine (0/1) 0%
Thorax (0/1) 0%
Infections (1/1) 100%
Respiratory Physiology (0/1) 0%
Passmed