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Question 1
Correct
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From which germ cell layer does the GI tract initially develop?
Your Answer: Endoderm
Explanation:The GI tract forms from the endoderm. The endoderm grows laterally and then ventrally finally folding on its self to form the gut tube.
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This question is part of the following fields:
- Embryology
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Question 2
Correct
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Regarding fertilization & implantation:
Your Answer: The sperm head penetrates through the corona radiata & zona pellucida while the tail remains outside
Explanation:During fertilization, a sperm must first fuse with the plasma membrane and then penetrate the female egg cell to fertilize it. Fusing to the egg cell usually causes little problem, whereas penetrating through the egg’s hard shell or extracellular matrix can be more difficult. Therefore, sperm cells go through a process known as the acrosome reaction, which is the reaction that occurs in the acrosome of the sperm as it approaches the egg. The acrosome is a cap-like structure over the anterior half of the sperm’s head. Upon penetration, if all is normally occurring, the process of egg-activation occurs, and the oocyte is said to have become activated. This is thought to be induced by a specific protein phospholipase c zeta. It undergoes its secondary meiotic division, and the two haploid nuclei (paternal and maternal) fuse to form a zygote. To prevent polyspermy and minimize the possibility of producing a triploid zygote, several changes to the egg’s cell membranes render them impenetrable shortly after the first sperm enters the egg.
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This question is part of the following fields:
- Embryology
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Question 3
Correct
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The second meiotic division of the oocyte is normally completed:
Your Answer: After the sperm penetrates the secondary oocyte
Explanation:Upon penetration, if all is normally occurring, the process of egg-activation occurs, and the oocyte is said to have become activated. This is thought to be induced by a specific protein phospholipase c zeta. It undergoes its secondary meiotic division, and the two haploid nuclei (paternal and maternal) fuse to form a zygote.
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This question is part of the following fields:
- Embryology
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Question 4
Incorrect
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Ootidogenesis refers to which process during Oogenesis?
Your Answer: Growth and maturation
Correct Answer: 1st and 2nd Meiotic Divisions
Explanation:Oogonium become Primary Oocyte via Growth/Maturation. This process is called oocytogenesis Primary Oocyte undergoes 2 meiotic divisions to become Ootids. This process is called Ootidogenesis Ootids differentiate into Ovum
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This question is part of the following fields:
- Embryology
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Question 5
Correct
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All of the following are features of Turner's syndrome except:
Your Answer: The ovaries are usually well developed
Explanation:Turner syndrome patients have malfunctioning or streak ovaries due to which they can never conceive. It affects females, who will have a short stature, widely spaced nipples, webbed neck and karyotyping shows 45XO.
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This question is part of the following fields:
- Embryology
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Question 6
Correct
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Normal physiological gut herniation occurs at how many weeks gestation?
Your Answer: 8 weeks
Explanation:At about 8-12 weeks gestation, normal physiological herniation of the fetal bowel occurs. The midgut protrudes into the base of the umbilicus, and undergoes a 90-degree anticlockwise rotation. When the abdominal cavity enlarges enough to fit the developing midgut, the intestines undergo another 180-degree rotation before returning to the abdominal cavity.
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This question is part of the following fields:
- Embryology
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Question 7
Correct
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Turner's syndrome is characterised by :
Your Answer: Streak ovaries
Explanation:Turner syndrome, a condition that affects only females, results when one of the X chromosomes (sex chromosomes) is missing or partially missing. Turner syndrome can cause a variety of medical and developmental problems, including short height, failure of the ovaries to develop and heart defects. Streak ovaries are a form of ovarian dysgenesis and are associated with Turner syndrome. Occasionally they may be functional and secondary sexual characteristics may develop.
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This question is part of the following fields:
- Embryology
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Question 8
Correct
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Commonest cause of precocious puberty is:
Your Answer: Idiopathic
Explanation:Precocious puberty can be defined as secondary sexual characteristics that occur before the age of 8 years in females and 9 years in males. In 80-90% of individuals it is idiopathic. Other causes include CNS anomalies and tumours, increased exposure to sex hormones/steroids, pituitary gonadotrophin secreting tumours and ovarian tumours etc.
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This question is part of the following fields:
- Embryology
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Question 9
Incorrect
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Several mechanisms have been proposed as to what causes closure of the Ductus Arteriosus (DA) at Parturition. Which of the following is the most important in maintaining the patency of the DA during pregnancy?
Your Answer: PGE1
Correct Answer: PGE2
Explanation:Prostaglandin E1 and E2 help maintain the patency of the DA during pregnancy. PGE2 is by far the most potent and important. It is produced in large quantities by the placenta and the DA itself.
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This question is part of the following fields:
- Embryology
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Question 10
Incorrect
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Which one of the following statements is true regarding the development of external genitalia?
Your Answer: The genital smoothing forms the labia majora
Correct Answer: The genital fold forms the scrotum in males
Explanation:Genital folds lead to the formation of the scrotum in males while in females they form the posterior labial commissure. Genital tubercles form the labia majora whereas the tubercle itself becomes the mons pubis. The labia minora is formed by the urogenital folds.
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This question is part of the following fields:
- Embryology
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Question 11
Incorrect
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Regarding implantation, how many days after fertilisation does it typically occur?
Your Answer: 5
Correct Answer: 8
Explanation:Fertilization usually occurs in the fallopian tubes after ovulation. The zygote moves through the fallopian tube and implants in the endometrium about 7-9 days after fertilisation, or 6-12 days after ovulation.
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This question is part of the following fields:
- Embryology
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Question 12
Correct
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Question 13
Correct
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Question 14
Correct
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Branches V2 and V3 of the Trigeminal nerve develop from which pharyngeal arch?
Your Answer: 1st
Explanation:1st Arch = Trigeminal V2 & V3 (CN V) 2nd Arch = Facial (CN VII) 3rd Arch = Glossopharyngeal (CN IX) 4th and 6th Arches = Vagus (CN X)
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This question is part of the following fields:
- Embryology
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Question 15
Correct
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Which one of the following statements is true regarding androgen insensitivity syndrome?
Your Answer: They have no uterus
Explanation:Androgen insensitivity syndrome means that patients are phenotypically males but they are resistant or insensitive to male androgen hormones. They do not have a uterus. Due to insensitivity to androgens these patients often have female traits but their genetic makeup is of male, 46XY.
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This question is part of the following fields:
- Embryology
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Question 16
Incorrect
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How many days after fertilisation does the morula form?
Your Answer: 6
Correct Answer: 4
Explanation:When there are about 12-32 blastomeres, the developing human is referred to as morula. It enters the uterine cavity around the 4th day after fertilization.
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This question is part of the following fields:
- Embryology
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Question 17
Correct
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From which germ cell layer does the GI tract initially develop?
Your Answer: Endoderm
Explanation:GI Tract initially forms via gastrulation from the endoderm of the trilaminar embryo around week 3. It extends from the buccopharyngeal membrane to the cloacal membrane. Later in development there are contributions from all three germ cell layers.
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This question is part of the following fields:
- Embryology
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Question 18
Correct
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Androgen insensitivity syndrome is characterised by which one of the following karyotypes?
Your Answer: 46XY
Explanation:Genetically, patients suffering from androgen insensitivity syndrome are 46XY. They are males but insensitive to male hormones i.e. androgens.
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This question is part of the following fields:
- Embryology
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Question 19
Correct
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All of the following may result from a bicornuate uterus except:
Your Answer: Congenital anomalies of the baby
Explanation:Literature review shows that bicornuate uterus is associated with increase risk of spontaneous abortion in about 36% of patients. There is also an increased risk of preterm birth, malpresentation and fetal growth retardation.
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This question is part of the following fields:
- Embryology
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Question 20
Correct
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In a non-ovulating follicle, follicular growth is followed by:
Your Answer: Atresia
Explanation:During the ovulatory cycle, only one follicle will ovulate. The remaining non-ovulating follicles undergo disintegration. This process is known as atresia.
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This question is part of the following fields:
- Embryology
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